| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Wiescholleck, Denise Manahan-Vaugha. Persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis. Frontiers in integrative neuroscience. vol 7. 2013-03-20. PMID:23508474. |
persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis. |
2013-03-20 |
2023-08-12 |
rat |
| Valentina Wiescholleck, Denise Manahan-Vaugha. Persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis. Frontiers in integrative neuroscience. vol 7. 2013-03-20. PMID:23508474. |
nmdar hypofunction is believed to play a central role in the pathophysiology of both disorders and in an animal model of psychosis, that is based on irreversible antagonism of nmdars, pronounced deficits in hippocampal synaptic plasticity have been reported shortly after antagonist treatment. |
2013-03-20 |
2023-08-12 |
rat |
| Anthony J Baucum, Abigail M Brown, Roger J Colbra. Differential association of postsynaptic signaling protein complexes in striatum and hippocampus. Journal of neurochemistry. vol 124. issue 4. 2013-03-18. PMID:23173822. |
distinct physiological stimuli are required for bidirectional synaptic plasticity in striatum and hippocampus, but differences in the underlying signaling mechanisms are poorly understood. |
2013-03-18 |
2023-08-12 |
Not clear |
| R Boada, C Hutaff-Lee, A Schrader, D Weitzenkamp, T A Benke, E J Goldson, A C S Cost. Antagonism of NMDA receptors as a potential treatment for Down syndrome: a pilot randomized controlled trial. Translational psychiatry. vol 2. 2013-03-14. PMID:22806212. |
the n-methyl-d-aspartate (nmda) receptor uncompetitive antagonist, memantine hydrochloride (memantine), has been shown to improve learning/memory and rescue one form of hippocampus synaptic plasticity dysfunction in the best-studied mouse model of ds available, the ts65dn mouse. |
2013-03-14 |
2023-08-12 |
mouse |
| Dong-Mei Wang, Ya-Jun Yang, Li Zhang, Xu Zhang, Fei-Fei Guan, Lian-Feng Zhan. Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 14. issue 3. 2013-03-14. PMID:23478434. |
the amyloid-β (aβ)-induced impairment of hippocampal synaptic plasticity is an underlying mechanism of memory loss in the early stages of alzheimer's disease (ad) in human and mouse models. |
2013-03-14 |
2023-08-12 |
mouse |
| Sehrazat Kavraal, Sena Kara Oncu, Soner Bitiktas, A Seda Artis, Nazan Dolu, Tamer Gunes, Cem Sue. Maternal intake of Omega-3 essential fatty acids improves long term potentiation in the dentate gyrus and Morris water maze performance in rats. Brain research. vol 1482. 2013-03-12. PMID:22981414. |
molecular studies are needed to explain omega-3 effect on hippocampal synaptic plasticity. |
2013-03-12 |
2023-08-12 |
rat |
| Snigdha Roy, Nick Watkins, Detlef Hec. Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits. PloS one. vol 7. issue 9. 2013-03-12. PMID:22984567. |
absence of fmrp in fragile x patients as well as in fmr1 knockout (ko) mice results, among other changes, in abnormal dendritic spine formation and altered synaptic plasticity in the neocortex and hippocampus. |
2013-03-12 |
2023-08-12 |
mouse |
| Cheryl M McCormick, Catherine M Thomas, Cheryl S Sheridan, Feather Nixon, Jennifer A Flynn, Iva Z Mathew. Social instability stress in adolescent male rats alters hippocampal neurogenesis and produces deficits in spatial location memory in adulthood. Hippocampus. vol 22. issue 6. 2013-03-11. PMID:21805526. |
additionally, in experiment 2, a separate group of ss and ctl rats was tested on either a spatial (hippocampal-dependent) or nonspatial (nonhippocampal dependent) version of an object memory test and also were used to investigate hippocampal expression of markers of synaptic plasticity. |
2013-03-11 |
2023-08-12 |
rat |
| Cheryl M McCormick, Catherine M Thomas, Cheryl S Sheridan, Feather Nixon, Jennifer A Flynn, Iva Z Mathew. Social instability stress in adolescent male rats alters hippocampal neurogenesis and produces deficits in spatial location memory in adulthood. Hippocampus. vol 22. issue 6. 2013-03-11. PMID:21805526. |
as adults, ss and ctl rats did not differ in hippocampal expression of synaptophysin, but compared to ctl rats, ss rats had higher expression of basal calcium/calmodulin-dependent kinase ii (camkii), and lower expression of the phosphorylated camkii subunit threonine 286, signaling molecules related to synaptic plasticity. |
2013-03-11 |
2023-08-12 |
rat |
| Maria C Monti, Laura A Gabach, Mariela F Perez, Oscar A Ramíre. Impact of contextual cues in the expression of the memory associated with diazepam withdrawal: involvement of hippocampal PKMζ in vivo, and Arc expression and LTP in vitro. The European journal of neuroscience. vol 36. issue 8. 2013-03-06. PMID:22759216. |
hippocampal synaptic plasticity has been related to learning and adaptive processes developed during chronic drug administration, suggesting the existence of a common neurobiological mechanism mediating drug addiction and memory. |
2013-03-06 |
2023-08-12 |
Not clear |
| Maria C Monti, Laura A Gabach, Mariela F Perez, Oscar A Ramíre. Impact of contextual cues in the expression of the memory associated with diazepam withdrawal: involvement of hippocampal PKMζ in vivo, and Arc expression and LTP in vitro. The European journal of neuroscience. vol 36. issue 8. 2013-03-06. PMID:22759216. |
these results support the relevance of the hippocampal synaptic plasticity in the maintenance of the memory trace during benzodiazepines withdrawal, adding new evidences for common mechanisms between memory and drug addiction that can be intervened for treatment or prevention of this pathology. |
2013-03-06 |
2023-08-12 |
Not clear |
| V Wiescholleck, D Manahan-Vaugha. PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis. Translational psychiatry. vol 2. 2013-03-04. PMID:22832854. |
pde4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues mk801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis. |
2013-03-04 |
2023-08-12 |
rat |
| Lenora J Volk, Julia L Bachman, Richard Johnson, Yilin Yu, Richard L Hugani. PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory. Nature. vol 493. issue 7432. 2013-03-04. PMID:23283174. |
pkm-ζ is not required for hippocampal synaptic plasticity, learning and memory. |
2013-03-04 |
2023-08-12 |
mouse |
| Yang Shen, Wing-Yu Fu, Elaine Y L Cheng, Amy K Y Fu, Nancy Y I. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 2. 2013-03-04. PMID:23303927. |
melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase a-dependent mechanism. |
2013-03-04 |
2023-08-12 |
mouse |
| Yang Shen, Wing-Yu Fu, Elaine Y L Cheng, Amy K Y Fu, Nancy Y I. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 2. 2013-03-04. PMID:23303927. |
learning and memory require orchestrated regulation of both structural and functional synaptic plasticity in the hippocampus. |
2013-03-04 |
2023-08-12 |
mouse |
| Petri Takkala, Melanie A Woodi. Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Frontiers in cellular neuroscience. vol 7. 2013-03-04. PMID:23450426. |
disinhibition-mediated long-term potentiation (ltp) in the ca1 region of the hippocampus involves gabaergic synaptic plasticity at feedforward inhibitory inputs, resulting in the reduced shunting of glutamatergic excitatory currents. |
2013-03-04 |
2023-08-12 |
Not clear |
| Robbert Havekes, David A Canton, Alan J Park, Ted Huang, Ting Nie, Jonathan P Day, Leonardo A Guercio, Quinn Grimes, Vincent Luczak, Irwin H Gelman, George S Baillie, John D Scott, Ted Abe. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238728. |
here, we show that mice lacking the α-isoform of gravin have deficits in pka-dependent long-lasting forms of hippocampal synaptic plasticity including β2-adrenergic receptor-mediated plasticity, and selective impairments of long-term memory storage. |
2013-02-27 |
2023-08-12 |
mouse |
| Robbert Havekes, David A Canton, Alan J Park, Ted Huang, Ting Nie, Jonathan P Day, Leonardo A Guercio, Quinn Grimes, Vincent Luczak, Irwin H Gelman, George S Baillie, John D Scott, Ted Abe. Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 50. 2013-02-27. PMID:23238728. |
we conclude that gravin compartmentalizes a significant pool of pka that regulates learning-induced β2-adrenergic receptor signaling and erk activation in the hippocampus in vivo, thereby organizing molecular interactions between glutamatergic and noradrenergic signaling pathways for long-lasting synaptic plasticity, and memory storage. |
2013-02-27 |
2023-08-12 |
mouse |
| Jing Zhu, Hai-Dong Guo, Shui-Jin Sha. [Progress of researches on mechanisms of acupuncture intervention of Alzheimer's disease]. Zhen ci yan jiu = Acupuncture research. vol 37. issue 5. 2013-02-26. PMID:23342786. |
in the present paper, the authors reviewed development of studies on acupuncture treatment of ad from: 1) regulating release of neurotransmitters (cholinergic, amino-acids and monoamine neurotransmitters), 2) protecting cerebral neurons from apoptosis (anti-oxidative stress, improving synaptic plasticity, and suppressing apoptosis), 3) improving levels of neurotrophic factors, 4) regulating hippocampal intracellular signaling, 5) inhibiting inflammatory reactions of the brain tissue, 6) adjusting the level of abnormal proteins (microtubule-associated protein, beta-amyloid), and 7) up-regulating the level of autophagy activity. |
2013-02-26 |
2023-08-12 |
Not clear |
| Tao Tan, Bao-Liang Zhang, Xin Tia. [Chronic effects of oligomeric Aβ(1-42) on hippocampal synaptic plasticity in vivo]. Sheng li xue bao : [Acta physiologica Sinica]. vol 63. issue 3. 2013-02-21. PMID:21681340. |
[chronic effects of oligomeric aβ(1-42) on hippocampal synaptic plasticity in vivo]. |
2013-02-21 |
2023-08-12 |
rat |