| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Brunetti, G Orlando, B Michelotto, L Recinella, M Vacc. Cocaine- and amphetamine-regulated transcript peptide-(55-102) and thyrotropin releasing hormone inhibit hypothalamic dopamine release. European journal of pharmacology. vol 409. issue 2. 2001-02-15. PMID:11104823. |
considering the role played by dopamine in the central mechanisms of reward, these findings suggest that the inhibition of dopamine release could underlie the decreased appetitive behaviour induced by cart peptide-(55-102) and trh. |
2001-02-15 |
2023-08-12 |
rat |
| K D Carr, G Y Kim, S Cabeza de Vac. Chronic food restriction in rats augments the central rewarding effect of cocaine and the delta1 opioid agonist, DPDPE, but not the delta2 agonist, deltorphin-II. Psychopharmacology. vol 152. issue 2. 2001-02-08. PMID:11057524. |
the increased expression of c-fos in nucleus accumbens (nac) shell, in particular, suggests that food restriction may augment drug reward by modulating dopamine (da) synaptic function in this area. |
2001-02-08 |
2023-08-12 |
rat |
| J S Yeomans, J Takeuchi, M Baptista, D D Flynn, K Lepik, J Nobrega, J Fulton, M R Ralp. Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102495. |
brain-stimulation reward thresholds raised by an antisense oligonucleotide for the m5 muscarinic receptor infused near dopamine cells. |
2001-02-08 |
2023-08-12 |
rat |
| J S Yeomans, J Takeuchi, M Baptista, D D Flynn, K Lepik, J Nobrega, J Fulton, M R Ralp. Brain-stimulation reward thresholds raised by an antisense oligonucleotide for the M5 muscarinic receptor infused near dopamine cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 23. 2001-02-08. PMID:11102495. |
therefore, m5 muscarinic receptors associated with mesolimbic dopamine neurons seem to be important in brain-stimulation reward. |
2001-02-08 |
2023-08-12 |
rat |
| R N Cardinal, T W Robbins, B J Everit. The effects of d-amphetamine, chlordiazepoxide, alpha-flupenthixol and behavioural manipulations on choice of signalled and unsignalled delayed reinforcement in rats. Psychopharmacology. vol 152. issue 4. 2001-02-08. PMID:11140328. |
inability to tolerate delays to reward is an important component of impulsive behaviour, and has been suggested to reflect dysfunction of dopamine systems. |
2001-02-08 |
2023-08-12 |
rat |
| Y Fu, S G Matta, W Gao, B M Shar. Local alpha-bungarotoxin-sensitive nicotinic receptors in the nucleus accumbens modulate nicotine-stimulated dopamine secretion in vivo. Neuroscience. vol 101. issue 2. 2001-02-01. PMID:11074160. |
this fine tuning of the dopamine reward pathway through alpha7 nicotinic cholinergic receptors in the nucleus accumbens may amplify the secretion of dopamine, allowing a subthreshold brain concentration of nicotine to become an effective stimulus for dopamine secretion. |
2001-02-01 |
2023-08-12 |
Not clear |
| M G Feenstr. Dopamine and noradrenaline release in the prefrontal cortex in relation to unconditioned and conditioned stress and reward. Progress in brain research. vol 126. 2001-01-18. PMID:11105645. |
dopamine and noradrenaline release in the prefrontal cortex in relation to unconditioned and conditioned stress and reward. |
2001-01-18 |
2023-08-12 |
Not clear |
| J R Hollerman, L Tremblay, W Schult. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior. Progress in brain research. vol 126. 2001-01-18. PMID:11105648. |
dopamine neuron responses to both rewards and conditioned stimuli are not contingent on the behavior executed to obtain the reward and thus appear to reflect a relatively pure signal of a reward prediction error. |
2001-01-18 |
2023-08-12 |
Not clear |
| J R Hollerman, L Tremblay, W Schult. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior. Progress in brain research. vol 126. 2001-01-18. PMID:11105648. |
these activations observed in the striatum were often contingent on the behavioral act associated with obtaining reward, reflecting an integration of information not observed in dopamine neurons. |
2001-01-18 |
2023-08-12 |
Not clear |
| J R Hollerman, L Tremblay, W Schult. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior. Progress in brain research. vol 126. 2001-01-18. PMID:11105648. |
another difference between reward processing in striatal neurons and dopamine neurons is the influence of predictability on neuronal responsiveness. |
2001-01-18 |
2023-08-12 |
Not clear |
| J R Hollerman, L Tremblay, W Schult. Involvement of basal ganglia and orbitofrontal cortex in goal-directed behavior. Progress in brain research. vol 126. 2001-01-18. PMID:11105648. |
unlike dopamine neurons, many striatal neurons respond to predicted rewards, although at least some may reflect the relative degree of predictability in the magnitude of the responses to reward. |
2001-01-18 |
2023-08-12 |
Not clear |
| S Dehaene, J P Changeu. Reward-dependent learning in neuronal networks for planning and decision making. Progress in brain research. vol 126. 2001-01-18. PMID:11105649. |
at the molecular level, the reward signal is postulated to be a neurotransmitter such as dopamine, which exerts a global modulatory action on prefrontal synaptic efficacies, either via volume transmission or via targeted synaptic triads. |
2001-01-18 |
2023-08-12 |
human |
| D E Comings, K Blu. Reward deficiency syndrome: genetic aspects of behavioral disorders. Progress in brain research. vol 126. 2001-01-18. PMID:11105655. |
the dopaminergic and opioidergic reward pathways of the brain are critical for survival since they provide the pleasure drives for eating, love and reproduction; these are called 'natural rewards' and involve the release of dopamine in the nucleus accumbens and frontal lobes. |
2001-01-18 |
2023-08-12 |
human |
| D E Comings, K Blu. Reward deficiency syndrome: genetic aspects of behavioral disorders. Progress in brain research. vol 126. 2001-01-18. PMID:11105655. |
since the primary neurotransmitter of the reward pathway is dopamine, genes for dopamine synthesis, degradation, receptors, and transporters are reasonable candidates. |
2001-01-18 |
2023-08-12 |
human |
| J N Oak, J Oldenhof, H H Van To. The dopamine D(4) receptor: one decade of research. European journal of pharmacology. vol 405. issue 1-3. 2001-01-08. PMID:11033337. |
dopamine is an important neurotransmitter involved in motor control, endocrine function, reward, cognition and emotion. |
2001-01-08 |
2023-08-12 |
mouse |
| B Söderpalm, M Ericson, P Olausson, O Blomqvist, J A Enge. Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942035. |
ethanol shares with all major dependence producing drugs the ability to activate brain mesocorticolimbic dopamine neurons, an important part of the brain reward systems. |
2001-01-03 |
2023-08-12 |
mouse |
| E Hollander, A J Buchalter, C M DeCari. Pathological gambling. The Psychiatric clinics of North America. vol 23. issue 3. 2000-12-27. PMID:10986732. |
dopamine is linked to positive and negative reward, the addictive component of this disorder. |
2000-12-27 |
2023-08-12 |
Not clear |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
in addition, multiple lines of evidence suggest that the mesoaccumbens dopamine reward system is critically involved in the rewarding and reinforcing effects of ethanol. |
2000-12-22 |
2023-08-12 |
mouse |
| J M Boyce, F O Risinge. Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11033008. |
enhancement of ethanol reward by dopamine d3 receptor blockade. |
2000-12-21 |
2023-08-12 |
mouse |
| J M Boyce, F O Risinge. Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11033008. |
the results are consistent with the notion that dopamine d3 systems are important in the response to ethanol and further suggest that d3 receptor blockade increases ethanol reward. |
2000-12-21 |
2023-08-12 |
mouse |