| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
altered accumbens neural response to prediction of reward associated with place in dopamine d2 receptor knockout mice. |
2002-07-19 |
2023-08-12 |
mouse |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
the nucleus accumbens (nac) plays an important role in the integration of reward with motor function, and it receives dense dopamine innervation and extensive limbic and cortical afferents. |
2002-07-19 |
2023-08-12 |
mouse |
| Vincent David, Thomas P Durkin, Pierre Cazal. Differential effects of the dopamine D2/D3 receptor antagonist sulpiride on self-administration of morphine into the ventral tegmental area or the nucleus accumbens. Psychopharmacology. vol 160. issue 3. 2002-07-08. PMID:11889500. |
the involvement of dopamine neurotransmission in opiate reward remains controversial. |
2002-07-08 |
2023-08-12 |
Not clear |
| Nora D Volkow, Gene-Jack Wang, Joanna S Fowler, Jean Logan, Millard Jayne, Dinko Franceschi, Cristopher Wong, Samuel J Gatley, Andrew N Gifford, Yu-Shin Ding, Naomi Pappa. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse (New York, N.Y.). vol 44. issue 3. 2002-06-20. PMID:11954049. |
dopamine, a neurotransmitter involved with motivation and reward, its believed to regulate food intake in laboratory animals by modulating its rewarding effects through the nucleus accumbens (na). |
2002-06-20 |
2023-08-12 |
human |
| Nora D Volkow, Gene-Jack Wang, Joanna S Fowler, Jean Logan, Millard Jayne, Dinko Franceschi, Cristopher Wong, Samuel J Gatley, Andrew N Gifford, Yu-Shin Ding, Naomi Pappa. "Nonhedonic" food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect. Synapse (New York, N.Y.). vol 44. issue 3. 2002-06-20. PMID:11954049. |
these results provide the first evidence that dopamine in the dorsal striatum is involved in food motivation in humans that is distinct from its role in regulating reward through the na. |
2002-06-20 |
2023-08-12 |
human |
| Michael H Baumann, Mario A Ayestas, Lawrence G Sharpe, David B Lewis, Kenner C Rice, Richard B Rothma. Persistent antagonism of methamphetamine-induced dopamine release in rats pretreated with GBR12909 decanoate. The Journal of pharmacology and experimental therapeutics. vol 301. issue 3. 2002-06-19. PMID:12023554. |
in animals, the addictive properties of methamphetamine are mediated via release of dopamine (da) from nerve terminals in mesolimbic reward circuits. |
2002-06-19 |
2023-08-12 |
rat |
| Nelson Lezcano, Clare Bergso. D1/D5 dopamine receptors stimulate intracellular calcium release in primary cultures of neocortical and hippocampal neurons. Journal of neurophysiology. vol 87. issue 4. 2002-06-12. PMID:11929934. |
d1/d5 dopamine receptors in basal ganglia, hippocampus, and cerebral cortex modulate motor, reward, and cognitive behavior. |
2002-06-12 |
2023-08-12 |
Not clear |
| Venetia Zachariou, Marianne Benoit-Marand, Patrick B Allen, Peter Ingrassia, Allen A Fienberg, Francois Gonon, Paul Greengard, Marina R Picciott. Reduction of cocaine place preference in mice lacking the protein phosphatase 1 inhibitors DARPP 32 or Inhibitor 1. Biological psychiatry. vol 51. issue 8. 2002-06-06. PMID:11955461. |
modulation of protein phosphorylation by dopamine is thought to play an important role in drug reward. |
2002-06-06 |
2023-08-12 |
mouse |
| Lescia K Tremblay, Claudio A Naranjo, Laura Cardenas, Nathan Herrmann, Usoa E Bust. Probing brain reward system function in major depressive disorder: altered response to dextroamphetamine. Archives of general psychiatry. vol 59. issue 5. 2002-06-06. PMID:11982444. |
the state of the brain reward system in major depressive disorder was assessed with dextroamphetamine, which probes the release of dopamine within the mesocorticolimbic system, a major component of the brain reward system, and produces measurable behavioral changes, including rewarding effects (eg, euphoria). |
2002-06-06 |
2023-08-12 |
Not clear |
| Rafael Maldonado, Fernando Rodríguez de Fonsec. Cannabinoid addiction: behavioral models and neural correlates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 9. 2002-05-20. PMID:11978807. |
we review these models and the role of the cb1 cannabinoid receptor, the main target of natural cannabinoids, and its interaction with opioid and dopamine transmission in reward circuits. |
2002-05-20 |
2023-08-12 |
Not clear |
| Edmund J S Sonuga-Bark. Psychological heterogeneity in AD/HD--a dual pathway model of behaviour and cognition. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864715. |
in the other ad/hd is a motivational style characterised by an altered delay of reward gradient linked to the meso-limbic dopamine branch associated with the reward circuits (e.g. |
2002-05-16 |
2023-08-12 |
Not clear |
| Pernilla Grillner, Nicola B Mercur. Intrinsic membrane properties and synaptic inputs regulating the firing activity of the dopamine neurons. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864731. |
dopamine (da) neurones of the ventral mesencephalon are involved in the control of reward related behaviour, cognitive functions and motor performances, and provide a critical site of action for major categories of neuropsychiatric drugs, such as antipsychotic agents, dependence producing drugs and anti-parkinson medication. |
2002-05-16 |
2023-08-12 |
Not clear |
| Davide Viggiano, Gerasimos Grammatikopoulos, Adolfo G Sadil. A morphometric evidence for a hyperfunctioning mesolimbic system in an animal model of ADHD. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864733. |
the larger neuron size in both nhe and nle rats as compared with control rats, along with higher th expression mainly in the nhe, in absence of any relevant alteration in the sn, reveals an unbalance between the two dopamine systems and a subsequent alteration in limbic (reward, motivation, sustained attention) functions. |
2002-05-16 |
2023-08-12 |
rat |
| J K Melichar, M R Daglish, D J Nut. Addiction and withdrawal--current views. Current opinion in pharmacology. vol 1. issue 1. 2002-05-06. PMID:11712541. |
the final common pathway of addiction (the dopamine hypothesis of reward) has recently been evolving, with the mesocorticolimbic dopaminergic system now seen as key to natural rewards and drug-seeking behaviour, though perhaps having less of a role in the maintenance of such behaviour. |
2002-05-06 |
2023-08-12 |
Not clear |
| M Foster Olive, Michelle A Nannini, Christine J Ou, Heather N Koenig, Clyde W Hodg. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology. vol 437. issue 1-2. 2002-04-24. PMID:11864639. |
these compounds also delayed or suppressed ethanol-stimulated increases in nucleus accumbens dopamine release, suggesting that acamprosate and homotaurine may reduce ethanol intake by interfering with the ability of ethanol to activate the mesolimbic dopamine reward system. |
2002-04-24 |
2023-08-12 |
rat |
| Michele Hummel, Ellen M Unterwal. D1 dopamine receptor: a putative neurochemical and behavioral link to cocaine action. Journal of cellular physiology. vol 191. issue 1. 2002-04-15. PMID:11920678. |
in light of cocaine's multifarious effects on numerous neuronal systems, its effect on dopaminergic neurotransmission has attracted the most attention, particularly because of the implicated role of dopamine in brain reward. |
2002-04-15 |
2023-08-12 |
Not clear |
| Steven R Laviolette, Karim Nader, Derek van der Koo. Motivational state determines the functional role of the mesolimbic dopamine system in the mediation of opiate reward processes. Behavioural brain research. vol 129. issue 1-2. 2002-04-11. PMID:11809491. |
in opiate-withdrawn animals, but not in opiate-naive animals, suggesting that accumbal dopamine receptors are required for opiate reward signaling in drug-deprived motivational states. |
2002-04-11 |
2023-08-12 |
Not clear |
| Zhicheng Lin, George R Uh. Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism. Molecular pharmacology. vol 61. issue 4. 2002-04-11. PMID:11901228. |
cocaine's blockade of dopamine reuptake by brain dopamine transporters (dat) is a central feature of current understanding of cocaine reward and addiction. |
2002-04-11 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, J Russel Keath, Daniel S McGehe. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron. vol 33. issue 6. 2002-04-08. PMID:11906697. |
a single nicotine exposure increases dopamine levels in the mesolimbic reward system for hours, but nicotine concentrations experienced by smokers desensitize nachrs on dopamine neurons in seconds to minutes. |
2002-04-08 |
2023-08-12 |
Not clear |
| Huibert D Mansvelder, J Russel Keath, Daniel S McGehe. Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron. vol 33. issue 6. 2002-04-08. PMID:11906697. |
the net effect is a shift toward excitation of the dopamine reward system. |
2002-04-08 |
2023-08-12 |
Not clear |