| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caroline F Zink, Giuseppe Pagnoni, Megan E Martin, Mukeshwar Dhamala, Gregory S Bern. Human striatal response to salient nonrewarding stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 22. 2003-10-02. PMID:12954871. |
although one proposed function of both the striatum and its major dopamine inputs is related to coding rewards and reward-related stimuli, an alternative view suggests a more general role of the striatum in processing salient events, regardless of their reward value. |
2003-10-02 |
2023-08-12 |
human |
| S Potvin, E Stip, J-Y Ro. [Schizophrenia and addiction: An evaluation of the self-medication hypothesis]. L'Encephale. vol 29. issue 3 Pt 1. 2003-09-17. PMID:12876543. |
however, from a biological perspective, substance abuse among schizophrenic patients appears paradoxical: while the positive symptoms of schizophrenia might involve an hyperactivity of the reward system, the drugs of abuse all seem to increase dopamine release in that same system. |
2003-09-17 |
2023-08-12 |
Not clear |
| Richard Nass, Randy D Blakel. The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration. Annual review of pharmacology and toxicology. vol 43. 2003-09-09. PMID:12415122. |
the neurotransmitter dopamine (da) plays a central role in the coordination of movement, attention, and the recognition of reward. |
2003-09-09 |
2023-08-12 |
caenorhabditis_elegans |
| Charles A Dackis, Kevin G Lynch, Elmer Yu, Frederick F Samaha, Kyle M Kampman, James W Cornish, Amy Rowan, Sabrina Poole, Lenae White, Charles P O'Brie. Modafinil and cocaine: a double-blind, placebo-controlled drug interaction study. Drug and alcohol dependence. vol 70. issue 1. 2003-09-03. PMID:12681523. |
in addition, the neurotransmitter actions of modafinil are opposite to cocaine-induced neuroadaptations affecting dopamine and glutamate reward circuits. |
2003-09-03 |
2023-08-12 |
human |
| Michela Andreoli, Michela Tessari, Maria Pilla, Enzo Valerio, Jim J Hagan, Christian A Heidbrede. Selective antagonism at dopamine D3 receptors prevents nicotine-triggered relapse to nicotine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12700694. |
drugs of abuse, including, nicotine have been shown to enhance brain reward functions in the mesocortico-limbic dopamine (da) system in general, and the nucleus accumbens in particular. |
2003-09-02 |
2023-08-12 |
rat |
| Eliot L Gardne. Addictive potential of cannabinoids: the underlying neurobiology. Chemistry and physics of lipids. vol 121. issue 1-2. 2003-08-22. PMID:12505706. |
they enhance neural firing of a core dopamine (da) component of this meso-accumbens reward circuit; (3). |
2003-08-22 |
2023-08-12 |
Not clear |
| Erkki Tupala, Håkan Hall, Tuija Mantere, Pirkko Räsänen, Terttu Särkioja, Jari Tiihone. Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. NeuroImage. vol 19. issue 1. 2003-07-21. PMID:12781734. |
dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. |
2003-07-21 |
2023-08-12 |
human |
| Margery C Beinfel. What we know and what we need to know about the role of endogenous CCK in psychostimulant sensitization. Life sciences. vol 73. issue 6. 2003-07-17. PMID:12801586. |
the unique distribution of cck and its receptors and its co-localization with dopamine makes it ideally situated to pay a role in dopamine-mediated reward and psychostimulant sensitization. |
2003-07-17 |
2023-08-12 |
rat |
| Susan R Sesack, David B Car. Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiology & behavior. vol 77. issue 4-5. 2003-07-11. PMID:12526992. |
dopamine (da) neurons in the substantia nigra (sn) and ventral tegmental area (vta) form several projection systems with diverse functions, such as motor planning through the striatum, reward seeking via the nucleus accumbens (nac), and cognitive control through the prefrontal cortex (pfc). |
2003-07-11 |
2023-08-12 |
Not clear |
| Zhicheng Lin, Ping-Wu Zhang, Xuguang Zhu, Jean-Marc Melgari, Robin Huff, Rachel L Spieldoch, George R Uh. Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. The Journal of biological chemistry. vol 278. issue 22. 2003-07-10. PMID:12660249. |
the dopamine transporter (dat) modulates dopamine neurotransmission and is a primary target for psychostimulant influences on locomotion and reward. |
2003-07-10 |
2023-08-12 |
Not clear |
| Stephanie J Crag. Variable dopamine release probability and short-term plasticity between functional domains of the primate striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 10. 2003-06-25. PMID:12764127. |
release of the neuromodulator dopamine (da) is critical to the control of locomotion, motivation, and reward. |
2003-06-25 |
2023-08-12 |
marmoset |
| Valentina Bassareo, Maria Antonietta De Luca, Marzia Aresu, Alessandra Aste, Teresa Ariu, Gaetano Di Chiar. Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus. The European journal of neuroscience. vol 17. issue 7. 2003-06-20. PMID:12713649. |
these observations point to the existence of major differences in the adaptive regulation of nucleus accumbens dopamine transmission in the shell after drug as compared with taste reward. |
2003-06-20 |
2023-08-12 |
human |
| Paul Pentel, David Mali. A vaccine for nicotine dependence: targeting the drug rather than the brain. Respiration; international review of thoracic diseases. vol 69. issue 3. 2003-05-22. PMID:12097758. |
vaccination of rats against nicotine also reduces nicotine-induced dopamine release in the reward pathway of the brain and the reinstatement of nicotine responding, a model for relapse. |
2003-05-22 |
2023-08-12 |
rat |
| R A Rendon, L Shuster, N H Dodma. The effect of the NMDA receptor blocker, dextromethorphan, on cribbing in horses. Pharmacology, biochemistry, and behavior. vol 68. issue 1. 2003-05-20. PMID:11274707. |
dopamine in turn activates basal ganglia motor programs, reinforcing behavior via a reward mechanism. |
2003-05-20 |
2023-08-12 |
Not clear |
| István Gyertyán, Krisztina Gá. Dopamine D3 receptor ligands show place conditioning effect but do not influence cocaine-induced place preference. Neuroreport. vol 14. issue 1. 2003-04-25. PMID:12544838. |
the importance of dopamine d3 receptors in reward related processes, especially in cocaine addiction, has been investigated extensively. |
2003-04-25 |
2023-08-12 |
rat |
| William J A Eiler, Regat Seyoum, Katrina L Foster, Chaz Mailey, Harry L Jun. D1 dopamine receptor regulates alcohol-motivated behaviors in the bed nucleus of the stria terminalis in alcohol-preferring (P) rats. Synapse (New York, N.Y.). vol 48. issue 1. 2003-04-23. PMID:12557272. |
neuroanatomical studies have demonstrated that reciprocal projections exist from the bst to the ventral tegmental area (vta), a dopamine reward substrate proposed to play a role in alcohol abuse. |
2003-04-23 |
2023-08-12 |
rat |
| D P Figlewicz, S B Evans, J Murphy, M Hoen, D G Baski. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain research. vol 964. issue 1. 2003-04-18. PMID:12573518. |
we hypothesize that midbrain dopamine neurons, which have been implicated to be critical in the mediation of motivational and reward aspects of stimuli, contribute to these behavioral effects of insulin and leptin. |
2003-04-18 |
2023-08-12 |
rat |
| Christopher D Fiorillo, Philippe N Tobler, Wolfram Schult. Discrete coding of reward probability and uncertainty by dopamine neurons. Science (New York, N.Y.). vol 299. issue 5614. 2003-04-04. PMID:12649484. |
discrete coding of reward probability and uncertainty by dopamine neurons. |
2003-04-04 |
2023-08-12 |
Not clear |
| Christopher D Fiorillo, Philippe N Tobler, Wolfram Schult. Discrete coding of reward probability and uncertainty by dopamine neurons. Science (New York, N.Y.). vol 299. issue 5614. 2003-04-04. PMID:12649484. |
using distinct stimuli to indicate the probability of reward, we found that the phasic activation of dopamine neurons varied monotonically across the full range of probabilities, supporting past claims that this response codes the discrepancy between predicted and actual reward. |
2003-04-04 |
2023-08-12 |
Not clear |
| Jong Y Bahk, Shupeng Li, Moon S Park, Myeong O Ki. Dopamine D1 and D2 receptor mRNA up-regulation in the caudate-putamen and nucleus accumbens of rat brains by smoking. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452531. |
the neurotransmitter dopamine (da) is important in the reward and reinforcing properties of many addictive drugs: however, the effect of nicotine by cigarette smoking itself on the expression of da receptors in the caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (otu) has not been elucidated completely. |
2003-03-26 |
2023-08-12 |
rat |