| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jean-Antoine Girault, Paul Greengar. The neurobiology of dopamine signaling. Archives of neurology. vol 61. issue 5. 2004-06-17. PMID:15148138. |
dopamine neurons are also a central element in the brain reward system that controls the learning of many behaviors. |
2004-06-17 |
2023-08-12 |
human |
| Jean-Martin Beaulieu, Tatyana D Sotnikova, Wei-Dong Yao, Lisa Kockeritz, James R Woodgett, Raul R Gainetdinov, Marc G Caro. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 14. 2004-06-10. PMID:15044694. |
dopamine (da) is a neurotransmitter involved in the control of locomotion, emotion, cognition, and reward. |
2004-06-10 |
2023-08-12 |
mouse |
| Hiroyuki Mizoguchi, Kiyofumi Yamada, Makoto Mizuno, Tomoko Mizuno, Atsumi Nitta, Yukihiro Noda, Toshitaka Nabeshim. Regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors. Molecular pharmacology. vol 65. issue 5. 2004-05-28. PMID:15102958. |
regulations of methamphetamine reward by extracellular signal-regulated kinase 1/2/ets-like gene-1 signaling pathway via the activation of dopamine receptors. |
2004-05-28 |
2023-08-12 |
rat |
| Ameneh Rezayof, Mohammad-Reza Zarrindast, Hedayat Sahraei, Ali Haeri-Rohan. Involvement of dopamine receptors of the dorsal hippocampus on the acquisition and expression of morphine-induced place preference in rats. Journal of psychopharmacology (Oxford, England). vol 17. issue 4. 2004-05-07. PMID:14870954. |
it is concluded that dorsal hippocampal dopamine receptors may play an active role in morphine reward. |
2004-05-07 |
2023-08-12 |
rat |
| P Read Montague, Samuel M McClure, P R Baldwin, Paul E M Phillips, Evgeny A Budygin, Garret D Stuber, Michaux R Kilpatrick, R Mark Wightma. Dynamic gain control of dopamine delivery in freely moving animals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 7. 2004-05-04. PMID:14973252. |
activity changes in a large subset of midbrain dopamine neurons fulfill numerous assumptions of learning theory by encoding a prediction error between actual and predicted reward. |
2004-05-04 |
2023-08-12 |
rat |
| Mark A Ungless, Peter J Magill, J Paul Bola. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science (New York, N.Y.). vol 303. issue 5666. 2004-04-22. PMID:15044807. |
reward coding theories predict that dopamine neurons will be inhibited by or will not respond to aversive stimuli. |
2004-04-22 |
2023-08-12 |
rat |
| Mark A Ungless, Peter J Magill, J Paul Bola. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science (New York, N.Y.). vol 303. issue 5666. 2004-04-22. PMID:15044807. |
these findings suggest that dopamine neurons are specifically excited by reward and that a population of nondopamine neurons is excited by aversive stimuli. |
2004-04-22 |
2023-08-12 |
rat |
| Mufida El-Ghundi, Brian F O'Dowd, Mary Erclik, Susan R Georg. Attenuation of sucrose reinforcement in dopamine D1 receptor deficient mice. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603275. |
these results suggest that the dopamine d1 receptor plays a role in the motivation to work for reward (palatable food) but not in reward perception and is critical in learning new but relevant information and discontinuing previously learned responses. |
2004-04-21 |
2023-08-12 |
mouse |
| Conan Kornetsk. Brain-stimulation reward, morphine-induced oral stereotypy, and sensitization: implications for abuse. Neuroscience and biobehavioral reviews. vol 27. issue 8. 2004-04-19. PMID:15019427. |
along this vein results will be shown in which opiate antagonist block the dopamine agonist activation of the brain reward system as well as the corollary. |
2004-04-19 |
2023-08-12 |
rat |
| Raúl de la Fuente-Fernández, A Jon Stoess. The biochemical bases of the placebo effect. Science and engineering ethics. vol 10. issue 1. 2004-04-06. PMID:14986780. |
the observation that placebo administration induces the release of dopamine in the ventral striatum of patients with parkinson's disease suggests a link between the placebo effect and reward mechanisms. |
2004-04-06 |
2023-08-12 |
human |
| Wei-Dong Yao, Raul R Gainetdinov, Margaret I Arbuckle, Tatyana D Sotnikova, Michel Cyr, Jean-Martin Beaulieu, Gonzalo E Torres, Seth G N Grant, Marc G Caro. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron. vol 41. issue 4. 2004-03-30. PMID:14980210. |
to identify the molecular mechanisms underlying psychostimulant-elicited plasticity in the brain reward system, we undertook a phenotype-driven approach using genome-wide microarray profiling of striatal transcripts from three genetic and one pharmacological mouse models of psychostimulant or dopamine supersensitivity. |
2004-03-30 |
2023-08-12 |
mouse |
| George R Uh. Dopamine transporter: basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism. Movement disorders : official journal of the Movement Disorder Society. vol 18 Suppl 7. 2004-03-29. PMID:14531049. |
we review the basic science of the dopamine transporter (dat), a key neurotransmitter for locomotor control and reward systems, including those lost or deranged in parkinson's disease (pd). |
2004-03-29 |
2023-08-12 |
human |
| Hajime A Tokuno, Charles W Bradberry, Brian Everill, Samuel K Agulian, Steven Wilkes, Ronald M Baldwin, Gilles D Tamagnan, Jeffery D Kocsi. Local anesthetic effects of cocaethylene and isopropylcocaine on rat peripheral nerves. Brain research. vol 996. issue 2. 2004-03-10. PMID:14697493. |
because it has been reported that local anesthetic properties may influence the reinforcing effects of dopamine uptake inhibitors, we investigated the local anesthetic properties of cocaethylene as well as isopropylcocaine, another potential pharmacological tool in studies of cocaine reward and agonist substitution therapy. |
2004-03-10 |
2023-08-12 |
rat |
| George F Koo. Neuroadaptive mechanisms of addiction: studies on the extended amygdala. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 13. issue 6. 2004-03-01. PMID:14636960. |
neuropharmacologic studies in animal models of addiction have provided evidence for the dysregulation of specific neurochemical mechanisms not only in specific brain reward circuits (opioid peptides, gamma-aminobutyric acid, glutamate and dopamine) but also recruitment of brain stress systems (corticotropin-releasing factor) that provide the negative motivational state that drives addiction, and also are localized in the extended amygdala. |
2004-03-01 |
2023-08-12 |
Not clear |
| Eliyahu Dremencov, Iris Gispan-Herman, Merav Rosenstein, Avivit Mendelman, David H Overstreet, Joseph Zohar, Gal Yadi. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687868. |
because of the central role of accumbal dopamine in the mediation of motivation and reward, our measurements were focused on dopaminergic neurotransmission in the nucleus accumbens (nac). |
2004-02-18 |
2023-08-12 |
rat |
| Zara M Fagen, Huibert D Mansvelder, J Russel Keath, Daniel S McGehe. Short- and long-term modulation of synaptic inputs to brain reward areas by nicotine. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684446. |
dopamine signaling in brain reward areas is a key element in the development of drug abuse and dependence. |
2004-02-13 |
2023-08-12 |
human |
| Roy A Wis. Dopamine and food reward: back to the elements. American journal of physiology. Regulatory, integrative and comparative physiology. vol 286. issue 1. 2004-02-10. PMID:14660469. |
dopamine and food reward: back to the elements. |
2004-02-10 |
2023-08-12 |
Not clear |
| John F Cryan, Fabrizio Gasparini, Gino van Heeke, Athina Marko. Non-nicotinic neuropharmacological strategies for nicotine dependence: beyond bupropion. Drug discovery today. vol 8. issue 22. 2004-02-10. PMID:14690633. |
these strategies focus on altering reward processes in the brain by modulating various neurotransmitter systems: the most promising include dopamine d(3) receptor antagonists, noradrenaline reuptake inhibitors, gaba(b) receptor agonists, metabotropic glutamate 5 (mglur5) receptor antagonists, cannabinoid cb1 receptor antagonists, and corticotropin releasing factor (crf) 1 receptor antagonists. |
2004-02-10 |
2023-08-12 |
Not clear |
| Ekrem Dere, Maria A De Souza-Silva, Bianca Topic, Richard E Spieler, Helmut L Haas, Joseph P Husto. Histidine-decarboxylase knockout mice show deficient nonreinforced episodic object memory, improved negatively reinforced water-maze performance, and increased neo- and ventro-striatal dopamine turnover. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 6. 2004-01-30. PMID:14657262. |
our past pharmacological and lesion studies indicated that the brain's histamine system exerts inhibitory effects on the brain's reinforcement respective reward system reciprocal to mesolimbic dopamine systems, thereby modulating learning and memory performance. |
2004-01-30 |
2023-08-12 |
mouse |
| Ekrem Dere, Maria A De Souza-Silva, Bianca Topic, Richard E Spieler, Helmut L Haas, Joseph P Husto. Histidine-decarboxylase knockout mice show deficient nonreinforced episodic object memory, improved negatively reinforced water-maze performance, and increased neo- and ventro-striatal dopamine turnover. Learning & memory (Cold Spring Harbor, N.Y.). vol 10. issue 6. 2004-01-30. PMID:14657262. |
here, we investigated the effects of an hdc gene disruption in the mouse in a nonreinforced object exploration task and a negatively reinforced water-maze task as well as on neo- and ventro-striatal dopamine systems known to be involved in brain reward and reinforcement. |
2004-01-30 |
2023-08-12 |
mouse |