| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernard Le Foll, Steven R Goldber. Cannabinoid CB1 receptor antagonists as promising new medications for drug dependence. The Journal of pharmacology and experimental therapeutics. vol 312. issue 3. 2005-04-05. PMID:15525797. |
in particular, they share the common property of activating mesolimbic dopamine brain reward systems, and virtually all abused drugs elevate dopamine levels in the nucleus accumbens. |
2005-04-05 |
2023-08-12 |
Not clear |
| Philippe N Tobler, Christopher D Fiorillo, Wolfram Schult. Adaptive coding of reward value by dopamine neurons. Science (New York, N.Y.). vol 307. issue 5715. 2005-03-24. PMID:15761155. |
adaptive coding of reward value by dopamine neurons. |
2005-03-24 |
2023-08-12 |
Not clear |
| Philippe N Tobler, Christopher D Fiorillo, Wolfram Schult. Adaptive coding of reward value by dopamine neurons. Science (New York, N.Y.). vol 307. issue 5715. 2005-03-24. PMID:15761155. |
in this way, dopamine neurons maintained their reward sensitivity over a large range of reward values. |
2005-03-24 |
2023-08-12 |
Not clear |
| Eric B Keverne, James P Curle. Vasopressin, oxytocin and social behaviour. Current opinion in neurobiology. vol 14. issue 6. 2005-03-23. PMID:15582383. |
male affiliative bonding depends upon release of both vasopressin and dopamine in the ventral striatum enhancing the reward value of odour cues that signal identity. |
2005-03-23 |
2023-08-12 |
Not clear |
| Andrew James Smith, Suzanna Becker, Shitij Kapu. A computational model of the functional role of the ventral-striatal D2 receptor in the expression of previously acquired behaviors. Neural computation. vol 17. issue 2. 2005-03-22. PMID:15720772. |
whether an internal model or the td approach (or a mixture) is better suited to a comprehensive exposition of tonic and phasic dopamine will have important implications for our understanding of reward, motivation, schizophrenia, and impulsivity. |
2005-03-22 |
2023-08-12 |
Not clear |
| Xingguang Luo, Henry Kranzler, Jaakko Lappalainen, Robert Rosenheck, Dennis Charney, Lingjun Zuo, Joseph Erdos, Daniel P van Kammen, Joel Gelernte. CALCYON gene variation, schizophrenia, and cocaine dependence. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 125B. issue 1. 2005-03-21. PMID:14755439. |
calcyon is a brain-specific d1 dopamine receptor-interacting protein, with a potential role in d1-mediated physiological processes, including motor control, reward mechanisms, and cognitive processes. |
2005-03-21 |
2023-08-12 |
human |
| Erkki Tupala, Jari Tiihone. Striatal dopamine D1 receptors in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography. Brain research. vol 1031. issue 1. 2005-03-18. PMID:15621009. |
in addition, considering the facts that dopamine d(1) receptors were more abundant in the mesolimbic nucleus accumbens than in the caudate or putamen and that there was a strong tendency towards lower binding among type 1 alcoholics may suggest the importance of dopamine d(1) receptors in reward and/or alcoholism. |
2005-03-18 |
2023-08-12 |
human |
| James K Rilling, Alan G Sanfey, Jessica A Aronson, Leigh E Nystrom, Jonathan D Cohe. Opposing BOLD responses to reciprocated and unreciprocated altruism in putative reward pathways. Neuroreport. vol 15. issue 16. 2005-03-14. PMID:15538191. |
mesencephalic dopamine neurons are believed to facilitate reward-dependent learning by computing errors in reward predictions. |
2005-03-14 |
2023-08-12 |
human |
| Niall P Murph. Nociceptin/orphanin FQ, hedonic state and the response to abused drugs. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 5. 2005-03-10. PMID:15658507. |
the mesolimbic dopamine and endogenous opioid systems are foremost in our understanding of the neurochemical systems implicated in the control of motivation and reward. |
2005-03-10 |
2023-08-12 |
Not clear |
| Erkki Tupala, Jari Tiihone. Dopamine and alcoholism: neurobiological basis of ethanol abuse. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 8. 2005-03-07. PMID:15588749. |
the role of the dopamine (da) system in brain reward mechanisms and the development of substance abuse has been well established. |
2005-03-07 |
2023-08-12 |
human |
| Kimber L Price, Lawrence D Middaug. The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice. Alcoholism, clinical and experimental research. vol 28. issue 11. 2005-03-01. PMID:15547453. |
the dopamine d1 antagonist reduces ethanol reward for c57bl/6 mice. |
2005-03-01 |
2023-08-12 |
mouse |
| P F Foley, E W Loh, D J Innes, S M Williams, A E G Tannenberg, C G Harper, P R Dod. Association studies of neurotransmitter gene polymorphisms in alcoholic Caucasians. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542698. |
ethanol enhances mesolimbic/cortical dopamine activity in reward and reinforcement circuits. |
2005-02-18 |
2023-08-12 |
Not clear |
| P F Foley, E W Loh, D J Innes, S M Williams, A E G Tannenberg, C G Harper, P R Dod. Association studies of neurotransmitter gene polymorphisms in alcoholic Caucasians. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542698. |
we investigated the hypothesis that risk for alcoholism may be mediated by genes for neurotransmitters associated with the dopamine reward system as well as genes for enzymes involved in ethanol metabolism. |
2005-02-18 |
2023-08-12 |
Not clear |
| F Scott Hall, Ichiro Sora, Jana Drgonova, Xiao-Fei Li, Michelle Goeb, George R Uh. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542699. |
the initially surprising observation that cocaine retains its rewarding effects in dopamine transporter (dat) knockout (ko) mice led our laboratory to examine the effects of deletion of other monoaminergic genes on cocaine reward. |
2005-02-18 |
2023-08-12 |
mouse |
| F Scott Hall, Ichiro Sora, Jana Drgonova, Xiao-Fei Li, Michelle Goeb, George R Uh. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542699. |
overall, these studies indicate important requirements for several monoaminergic system genes to fully explain cocaine reward, in particular those expressed by dopamine and serotonin systems. |
2005-02-18 |
2023-08-12 |
mouse |
| Naoyuki Hironaka, Kazutaka Ikeda, Ichiro Sora, George R Uhl, Hiroaki Nik. Food-reinforced operant behavior in dopamine transporter knockout mice: enhanced resistance to extinction. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542711. |
dopamine (da) plays roles in circuits that are important for brain reward and in striatal brain regions that are important for certain types of habit learning. |
2005-02-18 |
2023-08-12 |
mouse |
| Chana K Akins, Neil Levens, Robert Prather, Brad Cooper, Tim Frit. Dose-dependent cocaine place conditioning and D1 dopamine antagonist effects in male Japanese quail. Physiology & behavior. vol 82. issue 2-3. 2005-02-17. PMID:15276793. |
the dopamine d1 receptor subtype has been implicated in drug reward processes in mammals. |
2005-02-17 |
2023-08-12 |
Not clear |
| Lavina J Faleiro, Susan Jones, Julie A Kaue. Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15150533. |
drugs of abuse activate the reward circuitry of the mesocorticolimbic system, and it has been hypothesized that drug exposure triggers synaptic plasticity of glutamatergic synapses onto dopamine (da) neurons of the ventral tegmental area. |
2005-02-14 |
2023-08-12 |
Not clear |
| Haoran Wang, Karen Ng, David Hayes, Xiangrong Gao, Gina Forster, Charles Blaha, John Yeoman. Decreased amphetamine-induced locomotion and improved latent inhibition in mice mutant for the M5 muscarinic receptor gene found in the human 15q schizophrenia region. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 12. 2005-02-14. PMID:15213703. |
m5 muscarinic receptors are coexpressed with d2 dopamine receptors in the ventral tegmentum and striatum, and are important for reward in rodents. |
2005-02-14 |
2023-08-12 |
mouse |
| Stuart M White, Cheryl J T Lamb. The pathophysiology of cocaine abuse. Journal of clinical forensic medicine. vol 10. issue 1. 2005-02-10. PMID:15275044. |
cocaine is a naturally occurring alkaloid that increases dopamine concentrations in the reward centers of the brain. |
2005-02-10 |
2023-08-12 |
Not clear |