| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gregory Fricchione, George B Stefan. Placebo neural systems: nitric oxide, morphine and the dopamine brain reward and motivation circuitries. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 5. 2005-07-11. PMID:15874901. |
placebo neural systems: nitric oxide, morphine and the dopamine brain reward and motivation circuitries. |
2005-07-11 |
2023-08-12 |
Not clear |
| Gregory Fricchione, George B Stefan. Placebo neural systems: nitric oxide, morphine and the dopamine brain reward and motivation circuitries. Medical science monitor : international medical journal of experimental and clinical research. vol 11. issue 5. 2005-07-11. PMID:15874901. |
constitutive nitric oxide levels play a role in the modulation of dopamine outflow in the nigrostriatal movement and the mesolimbic and mesocortical reward and motivation circuitries. |
2005-07-11 |
2023-08-12 |
Not clear |
| B J Hoplight, E S Vincow, J F Neumaie. The effects of SB 224289 on anxiety and cocaine-related behaviors in a novel object task. Physiology & behavior. vol 84. issue 5. 2005-06-24. PMID:15885246. |
specifically, activation of 5-ht1b receptors in vta during cocaine exposure increases dopamine release in nacc and enhances cocaine-induced locomotor activity, reward, and reinforcement. |
2005-06-24 |
2023-08-12 |
Not clear |
| Nicolas Maurice, Jeff Mercer, C Savio Chan, Salvador Hernandez-Lopez, Joshua Held, Tatiana Tkatch, D James Surmeie. D2 dopamine receptor-mediated modulation of voltage-dependent Na+ channels reduces autonomous activity in striatal cholinergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 46. 2005-06-21. PMID:15548642. |
intrastriatal release of dopamine and inhibition of interneuron activity is thought to be a critical link between behaviorally relevant events, such as reward, and alterations in striatal function. |
2005-06-21 |
2023-08-12 |
Not clear |
| Shin Hye Kim, Yu Mi Choi, Sungkwon Chung, Dae Yong Uhm, Myoung Kyu Par. Two different Ca2+-dependent inhibitory mechanisms of spontaneous firing by glutamate in dopamine neurons. Journal of neurochemistry. vol 91. issue 4. 2005-05-25. PMID:15525352. |
the excitatory neurotransmitter, glutamate, generates a characteristic burst-pause type of firing in midbrain dopamine neurons in association with the reward behavior, but the cellular mechanism by which glutamate generates these bursts is unknown. |
2005-05-25 |
2023-08-12 |
Not clear |
| Anna Molander, Bo Söderpal. Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654288. |
ethanol (etoh), like other drugs of abuse, increases extracellular dopamine (da) levels in the nucleus accumbens (nac) of the brain reward system, an effect that may be of importance for alcohol addiction. |
2005-05-25 |
2023-08-12 |
Not clear |
| Abdalla Bowirrat, Marlene Oscar-Berma. Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 132B. issue 1. 2005-05-12. PMID:15457501. |
when the mesocorticolimbic dopamine reward system dysfunctions (perhaps caused by certain genetic variants), the end result is reward deficiency syndrome and subsequent drug-seeking behaviors. |
2005-05-12 |
2023-08-12 |
Not clear |
| Mark A Ungles. Dopamine: the salient issue. Trends in neurosciences. vol 27. issue 12. 2005-05-12. PMID:15541509. |
there is general agreement that midbrain dopamine neurons play key roles in reward processing. |
2005-05-12 |
2023-08-12 |
Not clear |
| J D Salamone, M Correa, S M Mingote, S M Webe. Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. Current opinion in pharmacology. vol 5. issue 1. 2005-05-04. PMID:15661623. |
beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. |
2005-05-04 |
2023-08-12 |
Not clear |
| J D Salamone, M Correa, S M Mingote, S M Webe. Beyond the reward hypothesis: alternative functions of nucleus accumbens dopamine. Current opinion in pharmacology. vol 5. issue 1. 2005-05-04. PMID:15661623. |
according to the dopamine (da) hypothesis of reward, da systems in the brain, particularly in the nucleus accumbens, are thought to directly mediate the rewarding or primary motivational characteristics of natural stimuli such as food, water and sex, as well as various drugs of abuse. |
2005-05-04 |
2023-08-12 |
Not clear |
| Eliyahu Dremencov, Michael E Newman, Noa Kinor, Gitit Blatman-Jan, Cheryl J Schindler, David H Overstreet, Gal Yadi. Hyperfunctionality of serotonin-2C receptor-mediated inhibition of accumbal dopamine release in an animal model of depression is reversed by antidepressant treatment. Neuropharmacology. vol 48. issue 1. 2005-04-28. PMID:15617725. |
dopamine release in the nucleus accumbens mediates motivation and reward, making it a likely candidate to be involved in anhedonia, one of the major symptoms of depression. |
2005-04-28 |
2023-08-12 |
rat |
| Kwang-Ho Choi, Robert L H Clements, Andrew J Greensha. Simultaneous AMPA/kainate receptor blockade and dopamine D(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats. Behavioural brain research. vol 158. issue 1. 2005-04-25. PMID:15680196. |
simultaneous ampa/kainate receptor blockade and dopamine d(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats. |
2005-04-25 |
2023-08-12 |
rat |
| Kwang-Ho Choi, Robert L H Clements, Andrew J Greensha. Simultaneous AMPA/kainate receptor blockade and dopamine D(2/3) receptor stimulation in the nucleus accumbens decreases brain stimulation reward in rats. Behavioural brain research. vol 158. issue 1. 2005-04-25. PMID:15680196. |
interactions between dopamine (da) and glutamate (glu) in the mesocorticolimbic pathway of the brain may influence motivation and reward. |
2005-04-25 |
2023-08-12 |
rat |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Taketoshi On. Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 6. 2005-04-22. PMID:15684065. |
dopamine d1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place. |
2005-04-22 |
2023-08-12 |
mouse |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Taketoshi On. Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 6. 2005-04-22. PMID:15684065. |
the present study investigated the specific contribution of dopamine d1 receptor (d1r) in mediating reward, locomotor activity, and spatial associative processes and in regulating nac neural responses. |
2005-04-22 |
2023-08-12 |
mouse |
| Ruth Sharf, David Y Lee, Robert Ranald. Microinjections of SCH 23390 in the ventral tegmental area reduce operant responding under a progressive ratio schedule of food reinforcement in rats. Brain research. vol 1033. issue 2. 2005-04-13. PMID:15694922. |
we recently demonstrated that dopamine d1 receptors in the ventral tegmental area (vta) are involved in intravenous cocaine reward. |
2005-04-13 |
2023-08-12 |
rat |
| Ruth Sharf, David Y Lee, Robert Ranald. Microinjections of SCH 23390 in the ventral tegmental area reduce operant responding under a progressive ratio schedule of food reinforcement in rats. Brain research. vol 1033. issue 2. 2005-04-13. PMID:15694922. |
here, we investigated whether vta d1 receptors also are involved in food reward by testing the hypothesis that blockade of dopamine d1 receptors in the vta attenuates the rewarding effects of food. |
2005-04-13 |
2023-08-12 |
rat |
| Ruth Sharf, David Y Lee, Robert Ranald. Microinjections of SCH 23390 in the ventral tegmental area reduce operant responding under a progressive ratio schedule of food reinforcement in rats. Brain research. vol 1033. issue 2. 2005-04-13. PMID:15694922. |
these data suggest that dendritically released dopamine in the vta plays a significant role in food reward. |
2005-04-13 |
2023-08-12 |
rat |
| Kristopher M Kahlig, Francesca Binda, Habibeh Khoshbouei, Randy D Blakely, Douglas G McMahon, Jonathan A Javitch, Aurelio Gall. Amphetamine induces dopamine efflux through a dopamine transporter channel. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 9. 2005-04-13. PMID:15728379. |
drugs of abuse, including cocaine, amphetamine (amph), and heroin, elevate extracellular dopamine (da) levels in the brain, thereby altering the activity/plasticity of reward circuits and precipitating addiction. |
2005-04-13 |
2023-08-12 |
Not clear |
| M E Walton, P L Croxson, M F S Rushworth, D M Bannerma. The mesocortical dopamine projection to anterior cingulate cortex plays no role in guiding effort-related decisions. Behavioral neuroscience. vol 119. issue 1. 2005-04-12. PMID:15727537. |
both mesolimbic dopamine (da) and the anterior cingulate cortex (acc) have been implicated in enabling animals to expend effort to obtain greater reward. |
2005-04-12 |
2023-08-12 |
rat |