| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel A Abrams, Percy K Mistry, Amanda E Baker, Aarthi Padmanabhan, Vinod Meno. A neurodevelopmental shift in reward circuitry from mother's to nonfamilial voices in adolescence. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-04-28. PMID:35483917. |
using functional brain imaging of human voice processing in children and adolescents (ages 7-16), we demonstrate distinct neural signatures for mother's voice and nonfamilial voices across child and adolescent development in reward and social valuation systems, instantiated in nucleus accumbens and ventromedial prefrontal cortex. |
2022-04-28 |
2023-08-13 |
human |
| Rui Chang, Jionghong Peng, Yunfan Chen, Hailin Liao, Size Zhao, Ju Zou, Sijie Ta. Deep Brain Stimulation in Drug Addiction Treatment: Research Progress and Perspective. Frontiers in psychiatry. vol 13. 2022-04-25. PMID:35463506. |
addiction is characterized by neuroplastic changes in the nucleus accumbens (nac), a key structure in the brain reward system, and dbs in this region has shown promising treatment effects. |
2022-04-25 |
2023-08-13 |
Not clear |
| Darius D Becker-Krail, Kyle D Ketchesin, Jennifer N Burns, Wei Zong, Mariah A Hildebrand, Lauren M DePoy, Chelsea A Vadnie, George C Tseng, Ryan W Logan, Yanhua H Huang, Colleen A McClun. Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior. Biological psychiatry. 2022-04-24. PMID:35461698. |
however, no studies to date have identified the role of circadian astrocyte function in the nucleus accumbens (nac), a hub for reward regulation, or determined the importance of these rhythms for reward-related behavior. |
2022-04-24 |
2023-08-13 |
human |
| Beatriz de la Puente, Daniel Zamanillo, Luz Romero, Alicia Carceller, José Miguel Vela, Manuel Merlos, Enrique Portillo-Salid. Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma-1 Receptor. ACS pharmacology & translational science. vol 5. issue 4. 2022-04-18. PMID:35434530. |
we explored a putative chronic pain-induced dysregulation of monoamine function by measuring monoamine levels in the nucleus accumbens (nac), a well-known brain reward area. |
2022-04-18 |
2023-08-13 |
mouse |
| Shi Yu Chan, Zi Yan Ong, Zhen Ming Ngoh, Yap Seng Chong, Juan H Zhou, Marielle V Fortier, Lourdes M Daniel, Anqi Qiu, Michael J Meaney, Ai Peng Ta. Structure-function coupling within the reward network in preschool children predicts executive functioning in later childhood. Developmental cognitive neuroscience. vol 55. 2022-04-12. PMID:35413663. |
the nucleus accumbens (nac) and orbitofrontal cortex (ofc) are activated by reward-related tasks and identified as key nodes of the brain circuit that underlie reward processing. |
2022-04-12 |
2023-08-13 |
Not clear |
| Inês M Amaral, Alex Hofer, Rana El Rawa. Implication of Extracellular Signal-Regulated Kinase in the Expression of Natural Reward: Evidence Not Found. Frontiers in behavioral neuroscience. vol 16. 2022-04-04. PMID:35368299. |
in this study, we compared erk activation in the nucleus accumbens (nac) after cocaine reward and after positive social interaction (si) with a partner-reward in male rats. |
2022-04-04 |
2023-08-13 |
rat |
| Peng Liu, Jialong Liang, Fengze Jiang, Wanshi Cai, Fang Shen, Jing Liang, Jianjun Zhang, Zhongsheng Sun, Nan Su. Genes. vol 13. issue 3. 2022-03-25. PMID:35328106. |
the basolateral amygdala (bla) is involved in the drug-cue association, while the nucleus accumbens (nac) responds to the drug reward. |
2022-03-25 |
2023-08-13 |
Not clear |
| Yasmin Olsson, Helga Lidö, Mia Ericson, Bo Söderpal. The glycine-containing dipeptide leucine-glycine raises accumbal dopamine levels in a subpopulation of rats presenting a lower endogenous dopamine tone. Journal of neural transmission (Vienna, Austria : 1996). 2022-03-24. PMID:35322277. |
interventions that elevate glycine levels and target the glycine receptor (glyr) in the nucleus accumbens (nac) reduce ethanol intake in rats, supposedly by acting on the brain reward system via increased basal and attenuated ethanol-induced nac dopamine release. |
2022-03-24 |
2023-08-13 |
mouse |
| Pawel K Olszewski, Emily E Noble, Luis Paiva, Yoichi Ueta, James E Blevin. Oxytocin as a potential pharmacological tool to combat obesity. Journal of neuroendocrinology. 2022-02-22. PMID:35192207. |
its effects on feeding have largely been attributed to limiting meal size through interactions in key regulatory brain regions governing the homeostatic control of food intake such as the hypothalamus and hindbrain in addition to key feeding reward areas such as the nucleus accumbens and ventral tegmental area. |
2022-02-22 |
2023-08-13 |
mouse |
| Ito Kawakami, Shuji Iritani, Yuichi Riku, Kentaro Umeda, Mina Takase, Kenji Ikeda, Kazuhiro Niizato, Tomio Arai, Mari Yoshida, Kenichi Oshima, Masato Hasegaw. Neuropathological investigation of patients with prolonged anorexia nervosa. Psychiatry and clinical neurosciences. 2022-02-15. PMID:35167165. |
this study aims to identify alterations of the reward circuitry regions, especially in the nucleus accumbens (nacc), using an brain tissues. |
2022-02-15 |
2023-08-13 |
Not clear |
| Hong-Ju Yang, Briana J Hempel, Guo-Hua Bi, Yi He, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. Elevation of extracellular glutamate by blockade of astrocyte glutamate transporters inhibits cocaine reinforcement in rats via a NMDA-GluN2B receptor mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-01-29. PMID:35091501. |
in this study, we systemically evaluated the effects of multiple glutamate transporter (glt) inhibitors on extracellular glutamate and dopamine (da) in the nucleus accumbens (nac), intravenous cocaine self-administration, intracranial brain-stimulation reward, and reinstatement of cocaine seeking in male and female rats. |
2022-01-29 |
2023-08-13 |
rat |
| Jianfeng Liu, Ruyan Wu, Robert Seaman, Kevin M Manz, Bernard Johnson, Jimmy Vu, Yufei Huang, Yanan Zhang, Alfred J Robison, Rachael Neve, Brad A Grueter, David Dietz, Jun-Xu L. TAAR1 regulates drug-induced reinstatement of cocaine-seeking via negatively modulating CaMKIIα activity in the NAc. Molecular psychiatry. 2022-01-26. PMID:35079125. |
we focused on the shell subregion of nucleus accumbens (nac), a key brain region of the brain reward system. |
2022-01-26 |
2023-08-13 |
rat |
| Imre Kalló, Azar Omrani, Frank J Meye, Han de Jong, Zsolt Liposits, Roger A H Ada. Characterization of orexin input to dopamine neurons of the ventral tegmental area projecting to the medial prefrontal cortex and shell of nucleus accumbens. Brain structure & function. 2022-01-14. PMID:35029758. |
vta neurons are a central hub processing reward and motivation and target the medial prefrontal cortex (mpfc) and the shell part of nucleus accumbens (nacs). |
2022-01-14 |
2023-08-13 |
Not clear |
| Darius D Becker-Krail, Puja K Parekh, Kyle D Ketchesin, Shintaro Yamaguchi, Jun Yoshino, Mariah A Hildebrand, Brandon Dunham, Madhavi K Ganapathiraiu, Ryan W Logan, Colleen A McClun. Circadian Transcription Factor NPAS2 and the NAD+-Dependent Deacetylase SIRT1 Interact in the Mouse Nucleus Accumbens and Regulate Reward. The European journal of neuroscience. 2022-01-10. PMID:35001440. |
circadian transcription factor npas2 and the nad+-dependent deacetylase sirt1 interact in the mouse nucleus accumbens and regulate reward. |
2022-01-10 |
2023-08-13 |
mouse |
| Darius D Becker-Krail, Puja K Parekh, Kyle D Ketchesin, Shintaro Yamaguchi, Jun Yoshino, Mariah A Hildebrand, Brandon Dunham, Madhavi K Ganapathiraiu, Ryan W Logan, Colleen A McClun. Circadian Transcription Factor NPAS2 and the NAD+-Dependent Deacetylase SIRT1 Interact in the Mouse Nucleus Accumbens and Regulate Reward. The European journal of neuroscience. 2022-01-10. PMID:35001440. |
in the nucleus accumbens (nac), a region important for reward, both sirt1 and the circadian transcription factor neuronal pas domain protein 2 (npas2) are highly enriched, and both are regulated by the metabolic cofactor nad+. |
2022-01-10 |
2023-08-13 |
mouse |
| Salar Vaseghi, Shahram Zarrabian, Abbas Haghparas. Reviewing the role of the orexinergic system and stressors in modulating mood and reward-related behaviors. Neuroscience and biobehavioral reviews. 2022-01-01. PMID:34973302. |
cross-talk between the reward system and orexinergic signaling was also investigated, especially orexinergic signaling in the ventral tegmental area (vta), the nucleus accumbens (nac), and the hippocampus. |
2022-01-01 |
2023-08-13 |
Not clear |
| Hidenari Nomura, Cheol Son, Daisuke Aotani, Yoshiyuki Shimizu, Goro Katsuura, Michio Noguchi, Toru Kusakabe, Tomohiro Tanaka, Takashi Miyazawa, Kiminori Hosoda, Kazuwa Naka. Impaired leptin responsiveness in the nucleus accumbens of leptin-overexpressing transgenic mice with dysregulated sucrose and lipid preference independent of obesity. Neuroscience research. 2021-12-31. PMID:34971637. |
however, compared to wt-cd1w mice, leptg-hfd1w mice exhibited attenuated leptin-induced anorexia, decreased leptin-induced c-fos immunostaining in nucleus accumbens (nac), one of important site of reward system, decreased leptin-stimulated pstat3 immunostaining in hypothalamus. |
2021-12-31 |
2023-08-13 |
mouse |
| Katrina Y Choe, Richard A I Bethlehem, Martin Safrin, Hongmei Dong, Elena Salman, Ying Li, Valery Grinevich, Peyman Golshani, Laura A DeNardo, Olga Peñagarikano, Neil G Harris, Daniel H Geschwin. Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse. Neuron. 2021-12-21. PMID:34932941. |
notably, chemogenetically triggered release of endogenous oxytocin strongly stimulated the nucleus accumbens (nac), a forebrain nucleus implicated in social reward. |
2021-12-21 |
2023-08-13 |
mouse |
| Maria Schöne, Stephanie Seidenbecher, Jörn Kaufmann, Linda Antonella Antonucci, Thomas Frodl, Nikolaos Koutsouleris, Kolja Schiltz, Bernhard Bogert. Appetitive aggression is associated with lateralized activation in nucleus accumbens. Psychiatry research. Neuroimaging. vol 319. 2021-12-10. PMID:34891023. |
applying functional magnet resonance imaging (fmri), we tested whether 20 martial artists compared to 26 controls had a higher activation in the nucleus accumbens (nacc), a central part of the dopaminergic, mesolimbic reward system. |
2021-12-10 |
2023-08-13 |
human |
| Brandon J Polzin, Sarah A Heimovics, Lauren V Riter. Immunolabeling provides evidence for subregions in the songbird nucleus accumbens and suggests a context-dependent role in song in male European starlings (Sturnus vulgaris). Brain, behavior and evolution. 2021-12-08. PMID:34879382. |
the nucleus accumbens (nac) is a brain region well-known to mediate reward and motivation, which suggests it is an ideal candidate to regulate reward associated with gregarious song. |
2021-12-08 |
2023-08-13 |
Not clear |