| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zahra Ebrahimi, Nazanin Kahvandi, Elahe Shahriari, Alireza Komaki, Seyed Asaad Karimi, Marzieh Naderishahab, Maryam Sharifi, Abdolrahman Sarih. VU0155041, a positive allosteric modulator of mGluR4, in the nucleus accumbens facilitates extinction and inhibits the reinstatement of morphine-induced conditioned place preference in male rats. Brain research bulletin. 2023-03-30. PMID:36997034. |
nucleus accumbens (nac) neurons appear to be at the hub of the reward circuit. |
2023-03-30 |
2023-08-14 |
rat |
| Enrica Montalban, Albert Giralt, Lieng Taing, Yuki Nakamura, Assunta Pelosi, Mallory Brown, Benoit de Pins, Emmanuel Valjent, Miquel Martin, Angus C Nairn, Paul Greengard, Marc Flajolet, Denis Herv, Nicolas Gambardella, Jean-Pierre Roussarie, Jean-Antoine Giraul. Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of bioRxiv : the preprint server for biology. 2023-03-22. PMID:36945487. |
these effects involve the reward system and dopamine neurons, which modulate neurons in the nucleus accumbens (nac). |
2023-03-22 |
2023-08-14 |
Not clear |
| Kyle D Ketchesin, Darius D Becker-Krail, Xiangning Xue, Rashaun S Wilson, TuKiet T Lam, Kenneth R Williams, Angus C Nairn, George C Tseng, Ryan W Loga. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. bioRxiv : the preprint server for biology. 2023-03-13. PMID:36909659. |
repeated use of substances such as psychostimulants and opioids may lead to significant alterations in molecular rhythms in the nucleus accumbens (nac), a brain region central to reward and motivation. |
2023-03-13 |
2023-08-14 |
mouse |
| Seiya Ishino, Taisuke Kamada, Gideon A Sarpong, Julia Kitano, Reo Tsukasa, Hisa Mukohira, Fangmiao Sun, Yulong Li, Kenta Kobayashi, Honda Naoki, Naoya Oishi, Masaaki Ogaw. Dopamine error signal to actively cope with lack of expected reward. Science advances. vol 9. issue 10. 2023-03-10. PMID:36897945. |
the dopamine increase reflected in the nucleus accumbens correlated with behavioral adjustment to actively overcome unexpected no reward. |
2023-03-10 |
2023-08-14 |
rat |
| Eric Y Choi, Daniela Franco, Catherine A Stapf, Madeleine Gordin, Amanda Chow, Kara K Cover, Ramesh Chandra, Mary Kay Lob. Inducible CRISPR Epigenome Systems Mimic Cocaine Induced Bidirectional Regulation of Nab2 and Egr3. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-02-27. PMID:36849419. |
the nucleus accumbens (nac) is a major brain hub mediating reward behavior. |
2023-02-27 |
2023-08-14 |
Not clear |
| Sara Guarino, Christopher Hagen, Quynh Nguyen, Mauricio R Papin. Frustrative nonreward and the basal ganglia: Chemogenetic inhibition and excitation of the nucleus accumbens and globus pallidus externus during reward downshift. Neurobiology of learning and memory. 2023-02-23. PMID:36822464. |
frustrative nonreward and the basal ganglia: chemogenetic inhibition and excitation of the nucleus accumbens and globus pallidus externus during reward downshift. |
2023-02-23 |
2023-08-14 |
Not clear |
| Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronström, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology. 2023-02-21. PMID:36802012. |
the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). |
2023-02-21 |
2023-08-14 |
mouse |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports. vol 42. issue 2. 2023-02-08. PMID:36753418. |
distinct reward processing by subregions of the nucleus accumbens. |
2023-02-08 |
2023-08-14 |
Not clear |
| Gaowei Chen, Shishi Lai, Guo Bao, Jincan Ke, Xiaogao Meng, Shanshan Lu, Xiaocong Wu, Hua Xu, Fengyi Wu, Yu Xu, Fang Xu, Guo-Qiang Bi, Guangdun Peng, Kuikui Zhou, Yingjie Zh. Distinct reward processing by subregions of the nucleus accumbens. Cell reports. vol 42. issue 2. 2023-02-08. PMID:36753418. |
the nucleus accumbens (nac) plays an important role in motivation and reward processing. |
2023-02-08 |
2023-08-14 |
Not clear |
| Qiang Lyu, Hecun Zou, Li Luo, Wei Liu, Xiang He, Fei-Fei Shan. The Role of eIF5A1 in LPS-Induced Neuronal Remodeling of the Nucleus Accumbens in the Depression. Journal of integrative neuroscience. vol 22. issue 1. 2023-02-01. PMID:36722231. |
the nucleus accumbens (nac) is a key region in the brain that integrates reward signals. |
2023-02-01 |
2023-08-14 |
Not clear |
| Mirjam Wolfschlag, Anders Håkansso. Drug-Induced Gambling Disorder: Epidemiology, Neurobiology, and Management. Pharmaceutical medicine. 2023-01-07. PMID:36611111. |
the neurobiology of gd involves the reward and reinforcement system, based mainly on mesocorticolimbic dopamine projections, with the nucleus accumbens being a crucial area for developing addictions to substances and behaviors. |
2023-01-07 |
2023-08-14 |
Not clear |
| Laura C Ornelas, Giorgia Boero, Kalynn Van Voorhies, Todd K O'Buckley, Joyce Besheer, A Leslie Morro. Pharmacological administration of 3α,5α-THP into nucleus accumbens core increases 3α,5α-THP expression and reduces alcohol self-administration. Alcoholism, clinical and experimental research. 2023-01-01. PMID:36587947. |
alcohol affects multiple circuits in the brain, mainly disrupting the delicate balance between inhibitory γ-aminobutyric acid (gaba) transmission and excitatory glutamate signaling in brain areas involved in reward circuits, such as amygdala, nucleus accumbens (acb) and ventral tegmental area (vta), causing loss of control in circuits that regulate behavioral control of craving, alcohol-seeking and intake. |
2023-01-01 |
2023-08-14 |
human |
| Zheng Gan, Vijayan Gangadharan, Sheng Liu, Christoph Körber, Linette Liqi Tan, Han Li, Manfred Josef Oswald, Juhyun Kang, Jesus Martin-Cortecero, Deepitha Männich, Alexander Groh, Thomas Kuner, Sebastian Wieland, Rohini Kune. Layer-specific pain relief pathways originating from primary motor cortex. Science (New York, N.Y.). vol 378. issue 6626. 2022-12-22. PMID:36548429. |
we unexpectedly unraveled a connection from the m1 to the nucleus accumbens reward circuitry through a m1 layer 6-mediodorsal thalamus pathway, which specifically suppresses negative emotional valence and associated coping behaviors in neuropathic pain. |
2022-12-22 |
2023-08-14 |
Not clear |
| Hong Zhou, Jiayu Zhu, Jie Jia, Wei Xiang, Hualing Peng, Yuejin Zhang, Bo Liu, Yangling Mu, Yisheng L. The antidepressant effect of nucleus accumbens deep brain stimulation is mediated by parvalbumin-positive interneurons in the dorsal dentate gyrus. Neurobiology of stress. vol 21. 2022-12-19. PMID:36532368. |
the nucleus accumbens (nac) is a crucial region in the reward circuit and is related to anhedonia, the pivotal symptom of major depression disorder (mdd). |
2022-12-19 |
2023-08-14 |
mouse |
| Kathryn R Hill, David T Hsu, Stephan F Taylor, R Todd Ogden, Ramin V Parsey, Christine DeLorenz. Mu Opioid Receptor Dynamics in Healthy Volunteers with a History of Childhood Maltreatment. Journal of child & adolescent trauma. vol 15. issue 4. 2022-11-28. PMID:36439668. |
the mu opioid receptor rich nucleus accumbens and amygdala are critical to reward and stress processing respectively. |
2022-11-28 |
2023-08-14 |
human |
| Shuichi Chiba, Tadahiro Numakawa, Takuya Murata, Mitsumori Kawaminami, Toshiyuki Him. Enhanced social reward response and anxiety-like behavior with downregulation of nucleus accumbens glucocorticoid receptor in BALB/c mice. The Journal of veterinary medical science. 2022-11-20. PMID:36403974. |
enhanced social reward response and anxiety-like behavior with downregulation of nucleus accumbens glucocorticoid receptor in balb/c mice. |
2022-11-20 |
2023-08-14 |
mouse |
| Wanqi Che. Neural circuits provide insights into reward and aversion. Frontiers in neural circuits. vol 16. 2022-11-17. PMID:36389177. |
the aim of this paper is to summarize the latest findings on the mechanisms of the neural circuits associated with reward and aversion in a review of previous studies with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), and basal forebrain (bf). |
2022-11-17 |
2023-08-14 |
Not clear |
| Xuansong Mao, Kolter B Grigsby, Taylor J Kelty, Nathan R Kerr, Thomas E Childs, Frank W Boot. Transcriptomic analysis reveals novel molecular signaling networks in response to nucleus accumbens AP-1 inhibition in rats selectively bred for low voluntary wheel running behavior. Neuroscience. 2022-11-17. PMID:36395916. |
transcriptome analysis of the nucleus accumbens (nac; a brain region critical for pa reward and motivation) was performed to further determine molecular responses to intra-nac ap-1 inhibition in these rat lines. |
2022-11-17 |
2023-08-14 |
rat |
| Hasan Alhaddad, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Edward Melenski, Richard L Bell, Youssef Sar. Effects of a Novel Beta Lactam Compound, MC-100093, on the Expression of Glutamate Transporters/Receptors and Ethanol Drinking Behavior of Alcohol-Preferring Rats. The Journal of pharmacology and experimental therapeutics. vol 383. issue 3. 2022-11-17. PMID:36153003. |
chronic ethanol exposure affects the glutamatergic system in several brain reward regions including the nucleus accumbens (nac). |
2022-11-17 |
2023-11-20 |
rat |
| Jinlan Zhao, Lihong Ye, Zuyi Liu, Yongfei Cui, Di Deng, Shasha Bai, Lei Yang, Yafei Shi, Zhongqiu Liu, Rong Zhan. Protective Effects of Resveratrol on Adolescent Social Isolation-Induced Anxiety-Like Behaviors via Modulating Nucleus Accumbens Spine Plasticity and Mitochondrial Function in Female Rats. Nutrients. vol 14. issue 21. 2022-11-11. PMID:36364807. |
the nucleus accumbens (nac) is an important reward center implicated in psychiatric disorders. |
2022-11-11 |
2023-08-14 |
rat |