| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Caroline S Johnson, Andrew D Chapp, Erin B Lind, Mark J Thomas, Paul G Mermelstei. Sex differences in mouse infralimbic cortex projections to the nucleus accumbens shell. Biology of sex differences. vol 14. issue 1. 2023-12-12. PMID:38082417. |
the nucleus accumbens (nac) is an important region in motivation and reward. |
2023-12-12 |
2023-12-17 |
mouse |
| Albert J Qü, Lung-Hao Tai, Christopher D Hall, Emilie M Tu, Maria K Eckstein, Karyna Mishchanchuk, Wan Chen Lin, Juliana B Chase, Andrew F MacAskill, Anne G E Collins, Samuel J Gershman, Linda Wilbrech. Nucleus accumbens dopamine release reflects Bayesian inference during instrumental learning. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014354. |
dopamine release in the nucleus accumbens has been hypothesized to signal reward prediction error, the difference between observed and predicted reward, suggesting a biological implementation for reinforcement learning. |
2023-11-28 |
2023-11-29 |
Not clear |
| Kurt M Fraser, Val L Collins, Amy R Wolff, David J Ottenheimer, Kaisa N Bornhoft, Fiona Pat, Bridget J Chen, Patricia H Janak, Benjamin T Saunder. Contexts facilitate dynamic value encoding in the mesolimbic dopamine system. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961363. |
moreover, dopamine release in the nucleus accumbens following the conditioned stimulus only occurred when the occasion setter indicated it would predict reward. |
2023-11-14 |
2023-11-20 |
rat |
| Xiaohui Bai, Kun Zhang, Chaopeng Ou, Yanyu Mu, Dongmei Chi, Jianxing Zhang, Jingxiu Huang, Xile Li, Yingjun Zhang, Wan Huang, Handong Ouyan. AKAP150 from nucleus accumbens dopamine D1 and D2 receptor-expressing medium spiny neurons regulates morphine withdrawal. iScience. vol 26. issue 11. 2023-11-13. PMID:37953959. |
dopamine d1 receptor-expressing medium spiny neurons (d1r-msns) and dopamine d2 receptor-expressing msns (d2r-msns) in nucleus accumbens (nac) have been demonstrated to show different effects on reward and memory of abstinence. |
2023-11-13 |
2023-11-20 |
Not clear |
| Michał Sobstyl, Marek Prokopienko, Tadeusz Pietra. The ventral capsule and ventral striatum-Stereotactic targets for the management of treatment-resistant depression. A systematic literature review. Frontiers in psychiatry. vol 14. 2023-11-06. PMID:37928918. |
the main nucleus of the reward circuit is the nucleus accumbens (nac). |
2023-11-06 |
2023-11-08 |
Not clear |
| Maxi Becker, Yuhua Yu, Roberto Cabez. The influence of insight on risky decision making and nucleus accumbens activation. Scientific reports. vol 13. issue 1. 2023-10-11. PMID:37821507. |
reward in turn has been linked to dopaminergic signal transmission in the nucleus accumbens (nacc) and risky decision making. |
2023-10-11 |
2023-10-15 |
human |
| Chia-Yueh Chang, Yu-Chen Chan, Hsueh-Chih Che. The differential processing of verbal jokes by neural substrates in Indigenous and Han Chinese populations: An fMRI study. Behavioural brain research. 2023-10-09. PMID:37813282. |
ind participants when encountered with jokes displayed a greater activation of the mesolimbic dopaminergic reward system, including the amygdala, midbrain, and nucleus accumbens than han participants. |
2023-10-09 |
2023-10-15 |
human |
| Caleb J Browne, Philipp Mews, Xianxiao Zhou, Leanne M Holt, Molly Estill, Rita Futamura, Anne Schaefer, Paul J Kenny, Yasmin L Hurd, Li Shen, Bin Zhang, Eric J Nestle. Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine. bioRxiv : the preprint server for biology. 2023-10-02. PMID:37781621. |
substance use disorders (suds) induce widespread molecular dysregulation in the nucleus accumbens (nac), a brain region pivotal for coordinating motivation and reward. |
2023-10-02 |
2023-10-07 |
Not clear |
| Sarah M Barry, Gabriella M Barry, Dalia Martinez, Rachel D Penrod, Christopher W Cowa. The activity-regulated cytoskeleton-associated protein, Arc, functions in the nucleus accumbens shell to limit multiple triggers of cocaine-seeking behaviour. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753560. |
the activity-regulated cytoskeleton-associated protein (arc) is induced by cocaine in the nucleus accumbens (nac), an important brain reward region, but arc's nac function in sud-related behaviour remains unclear. |
2023-09-27 |
2023-10-07 |
rat |
| Romina Miranda-Olivos, Isabel Baenas, Trevor Steward, Roser Granero, Antoni Pastor, Isabel Sánchez, Asier Juaneda-Seguí, Amparo Del Pino-Gutiérrez, José A Fernández-Formoso, Nuria Vilarrasa, Fernando Guerrero-Pérez, Nuria Virgili, Rafael López-Urdiales, Susana Jiménez-Murcia, Rafael de la Torre, Carles Soriano-Mas, Fernando Fernández-Arand. Exploring the influence of circulating endocannabinoids and nucleus accumbens functional connectivity on anorexia nervosa severity. Molecular psychiatry. 2023-09-27. PMID:37759041. |
research suggests that alterations in the nucleus accumbens (nacc) and circulating endocannabinoids (ecbs), such as anandamide (aea) and 2-arachidonoylglycerol (2-ag), may contribute to increased severity and maladaptive behaviors in an, warranting an examination of the interplay between central reward circuitry and ecbs. |
2023-09-27 |
2023-10-07 |
Not clear |
| M Potega. How it ends: A review of behavioral and psychological phenomena, physiological processes and neural circuits in the termination of aggression in other animals and anger in people. Behavioural brain research. 2023-09-22. PMID:37739229. |
prolonged satiation of predatory behavior could involve habenula-regulated reduction of dopaminergic reward in nucleus accumbens. |
2023-09-22 |
2023-10-07 |
mouse |
| Amanda G Iglesias, Alvin S Chiu, Jason Wong, Paolo Campus, Fei Li, Zitong Nemo Liu, Jasmine K Bhatti, Shiv A Patel, Karl Deisseroth, Huda Akil, Christian R Burgess, Shelly B Flage. Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-09-14. PMID:37709540. |
prior work suggests that the behavior of sign-trackers is dopamine-dependent, and cue-elicited dopamine in the nucleus accumbens is believed to encode the incentive value of reward cues. |
2023-09-14 |
2023-10-07 |
rat |
| Stephanie Puig, Xiangning Xue, Ryan Salisbury, Micah A Shelton, Sam-Moon Kim, Mariah A Hildebrand, Jill R Glausier, Zachary Freyberg, George C Tseng, Anastasia K Yocum, David A Lewis, Marianne L Seney, Matthew L MacDonald, Ryan W Loga. Circadian rhythm disruptions associated with opioid use disorder in synaptic proteomes of human dorsolateral prefrontal cortex and nucleus accumbens. Molecular psychiatry. 2023-09-06. PMID:37674018. |
previous work indicated molecular rhythm disruptions in the human brain associated with oud, highlighting synaptic alterations in the dorsolateral prefrontal cortex (dlpfc) and nucleus accumbens (nac)-key brain regions involved in cognition and reward, and heavily implicated in the pathophysiology of oud. |
2023-09-06 |
2023-10-07 |
human |
| Pingping Zhao, Xing Chen, Arash Bellafard, Avaneesh Murugesan, Jonathan Quan, Daniel Aharoni, Peyman Golshan. Accelerated social representational drift in the nucleus accumbens in a model of autism. bioRxiv : the preprint server for biology. 2023-08-14. PMID:37577515. |
how the nucleus accumbens (nac), as a key hub of reward circuitry, encodes social interaction and whether these representations are altered in asd remain poorly understood. |
2023-08-14 |
2023-08-16 |
Not clear |
| Enrica Montalban, Albert Giralt, Lieng Taing, Yuki Nakamura, Assunta Pelosi, Mallory Brown, Benoit de Pins, Emmanuel Valjent, Miquel Martin, Angus C Nairn, Paul Greengard, Marc Flajolet, Denis Hervé, Nicolas Gambardella, Jean-Pierre Roussarie, Jean-Antoine Giraul. Operant training for highly palatable food alters translating mRNA in nucleus accumbens D2 neurons and reveals a modulatory role of Neurochondrin. Biological psychiatry. 2023-08-14. PMID:37579933. |
these effects involve the reward system and dopamine neurons, which modulate neurons in the nucleus accumbens (nac). |
2023-08-14 |
2023-09-07 |
Not clear |
| Simon Benoit, Mathilde Henry, Sara Fneich, Alexia Mathou, Lin Xia, Aline Foury, Mélanie Jouin, Claudine Junien, Lucile Capuron, Luc Jouneau, Marie-Pierre Moisan, Cyrille Delpierre, Anne Gabory, Muriel Darnaudér. Strain-specific changes in nucleus accumbens transcriptome and motivation for palatable food reward in mice exposed to maternal separation. Frontiers in nutrition. vol 10. 2023-08-11. PMID:37565037. |
strain-specific changes in nucleus accumbens transcriptome and motivation for palatable food reward in mice exposed to maternal separation. |
2023-08-11 |
2023-08-16 |
mouse |
| Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yak. N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice. Translational psychiatry. vol 13. issue 1. 2023-07-31. PMID:37524707. |
we first measured the ecbs and ecb-ls levels in different brain reward system regions following chronic alcohol self-administration using lc-ms. we have found that following chronic intermittent alcohol consumption, n-oleoyl glycine (olgly) levels were significantly elevated in the prefrontal cortex (pfc), and n-oleoyl alanine (olala) was significantly elevated in the pfc, nucleus accumbens (nac) and ventral tegmental area (vta) in a region-specific manner. |
2023-07-31 |
2023-08-14 |
mouse |
| Ioannis N Mavridis, Efstratios-Stylianos Pyrgeli. Nucleus accumbens changes in amyotrophic lateral sclerosis. American journal of neurodegenerative disease. vol 12. issue 3. 2023-07-17. PMID:37457842. |
the nucleus accumbens (na) is the ventral striatum's main part and is considered as a modulator of the human brain's reward network. |
2023-07-17 |
2023-08-14 |
human |
| Juan Enriquez-Traba, Hector E Yarur-Castillo, Rodolfo J Flores, Tenley Weil, Snehashis Roy, Ted B Usdin, Christina T LaGamma, Miguel Arenivar, Huikun Wang, Valerie S Tsai, Amy E Moritz, David R Sibley, Rosario Moratalla, Zachary Z Freyberg, Hugo A Tejed. Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors. bioRxiv : the preprint server for biology. 2023-07-10. PMID:37425766. |
dopamine release in striatal circuits, including the nucleus accumbens (nac), tracks separable features of reward such as motivation and reinforcement. |
2023-07-10 |
2023-08-14 |
Not clear |
| Daniela Neuhofer, Peter Kaliva. Differential modulation of GABAergic and glutamatergic neurons in the ventral pallidum by GABA and neuropeptides. eNeuro. 2023-07-06. PMID:37414552. |
the ventral pallidum (vp) is an integral locus in the reward circuitry and a major target of gabaergic innervation of both d1-medium spiny neurons (msns) and d2-msns from the nucleus accumbens (nac). |
2023-07-06 |
2023-08-14 |
mouse |