| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolette Driscoll, Marc-Joseph Antonini, Taylor M Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, Jill Venton, Polina Anikeev. Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In Vivo. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895451. |
their utility is demonstrated in studies of the mesolimbic reward pathway by simultaneously interfacing with the ventral tegmental area and nucleus accumbens in mice and characterizing the neurophysiological effects of a stimulant drug. |
2024-06-19 |
2024-06-21 |
mouse |
| Avril Gagnon-Chauvin, Mathieu Fornasier-Bélanger, Sandra W Jacobson, Joseph L Jacobson, Yohann Courtemanche, Pierre Ayotte, Richard E Bélanger, Gina Muckle, Dave Saint-Amou. Brain gray matter volume of reward-related structures in Inuit adolescents pre- and postnatally exposed to lead, mercury and polychlorinated biphenyls. Neurotoxicology. 2024-06-16. PMID:38880197. |
this study aimed to assess associations between prenatal and postnatal exposure to lead (pb), mercury (hg) and polychlorinated biphenyls (pcbs) and gray matter volume of key regions of the brain reward circuit, namely the caudate nucleus, putamen, nucleus accumbens (nacc), the amygdala, the orbitofrontal cortex (ofc) and the anterior cingulate cortex (acc). |
2024-06-16 |
2024-06-19 |
Not clear |
| Justin P Yuan, Emma L Jaeger, Saché M Coury, Jessica P Uy, Jessica L Buthmann, Tiffany C Ho, Ian H Gotli. Socioeconomic Disadvantage Moderates the Association of Systemic Inflammation with Amygdala Volume in Adolescents Over a Two-Year Interval: An Exploratory Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2024-06-11. PMID:38815859. |
affective areas of the brain involved in processing threat (e.g., amygdala) and reward (e.g., nucleus accumbens [nacc]) appear to be sensitive to inflammation. |
2024-06-11 |
2024-06-14 |
Not clear |
| Isabel C Duarte, Ana Dionísio, Joana Oliveira, Marco Simões, Rita Correia, Joana A Dias, Salomé Caldeira, João Redondo, Miguel Castelo-Branc. Neural underpinnings of ethical decisions in life and death dilemmas in naïve and expert firefighters. Scientific reports. vol 14. issue 1. 2024-06-08. PMID:38851794. |
these realistic life-saving dilemmas activate the same core reward and affective processing network, in particular the ventromedial prefrontal cortex, nucleus accumbens and amygdala, irrespective of prior expertise, thereby supporting general domain theories of ethical decision-making. |
2024-06-08 |
2024-06-11 |
Not clear |
| Alexis F League, Barkha J Yadav-Samudrala, Ramya Kolagani, Calista A Cline, Ian R Jacobs, Jonathan Manke, Micah J Niphakis, Benjamin F Cravatt, Aron H Lichtman, Bogna M Ignatowska-Jankowska, Sylvia Fittin. A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation. Frontiers in immunology. vol 15. 2024-06-05. PMID:38835765. |
cannabinoid anti-inflammatory effects are well documented, but therapeutic utility of cannabis remains limited due to its psychotropic effects, including alterations within brain regions encoding reward processing and motivation, such as the nucleus accumbens. |
2024-06-05 |
2024-06-07 |
human |
| Young-Jung Kim, Su Jeong Choi, Sa-Ik Hong, Jung-Cheol Park, Youyoung Lee, Shi-Xun Ma, Kwang-Hyun Hur, Young Lee, Kyeong-Man Kim, Hyung Kyu Kim, Hee Young Kim, Seok-Yong Lee, Se-Young Choi, Choon-Gon Jan. The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens. Molecular psychiatry. 2024-05-31. PMID:38822069. |
the ion channel trpa1 is a modulator of the cocaine reward circuit in the nucleus accumbens. |
2024-05-31 |
2024-06-02 |
mouse |
| Young-Jung Kim, Su Jeong Choi, Sa-Ik Hong, Jung-Cheol Park, Youyoung Lee, Shi-Xun Ma, Kwang-Hyun Hur, Young Lee, Kyeong-Man Kim, Hyung Kyu Kim, Hee Young Kim, Seok-Yong Lee, Se-Young Choi, Choon-Gon Jan. The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens. Molecular psychiatry. 2024-05-31. PMID:38822069. |
because the connection between pleasure and drug use becomes hard-wired in the nucleus accumbens (nac), which interfaces motivation, effective therapies need to modulate this mesolimbic reward system. |
2024-05-31 |
2024-06-02 |
mouse |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-28 |
2024-05-31 |
rat |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-26 |
2024-05-31 |
rat |
| Sanae Inokuchi-Sakata, Ryo Narita, Yukari Takahashi, Yozo Ishiuji, Akihiko Asahina, Fusao Kat. Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice - a model-free multivariate analysis. Molecular brain. vol 17. issue 1. 2024-05-24. PMID:38783364. |
to address this issue, we targeted the "reward center" of the brain, the nucleus accumbens (nac), in which itch-responsive neurons have been found in rodents. |
2024-05-24 |
2024-05-27 |
mouse |
| Shervin Assari, Payam Sheikhattar. Sex Differences in the Relationship Between Nucleus Accumbens Volume and Youth Tobacco or Marijuana Use Following Stressful Life Events. Journal of mental health & clinical psychology. vol 8. issue 2. 2024-05-18. PMID:38751734. |
these events may influence substance use by altering brain reward systems, especially the nucleus accumbens (nac), which plays a key role in motivated behaviors and reward processing. |
2024-05-18 |
2024-05-27 |
Not clear |
| Young-Jung Kim, Kyungin Kim, Youyoung Lee, Hee-Won Min, Yong-Hyun Ko, Bo-Ram Lee, Kwang-Hyun Hur, Seon-Kyung Kim, Seok-Yong Lee, Choon-Gon Jan. The mutated cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2 S968F) regulates cocaine-induced reward behaviour and plasticity in the nucleus accumbens. British journal of pharmacology. 2024-05-16. PMID:38751203. |
the mutated cytoplasmic fragile x mental retardation 1 (fmr1)-interacting protein 2 (cyfip2 s968f) regulates cocaine-induced reward behaviour and plasticity in the nucleus accumbens. |
2024-05-16 |
2024-05-27 |
mouse |
| Lorena Armijo Weingart, Loreto San Martin, Scarlet Gallegos, Anibal Araya, Macarena Konar Nie, Eduardo Fernandez-Pérez, Luis G Aguay. Loss of glycine receptors in the nucleus accumbens and ethanol reward in an Alzheimer´s Disease mouse model. Progress in neurobiology. 2024-05-09. PMID:38723884. |
loss of glycine receptors in the nucleus accumbens and ethanol reward in an alzheimer´s disease mouse model. |
2024-05-09 |
2024-05-27 |
mouse |
| Xiaolong Peng, Dillon J Connolly, Falon Sutton, John Robinson, Brenna Baker-Vogel, Edward B Short, Bashar W Badra. Non-invasive suppression of the human nucleus accumbens (NAc) with transcranial focused ultrasound (tFUS) modulates the reward network: a pilot study. Frontiers in human neuroscience. vol 18. 2024-04-17. PMID:38628972. |
non-invasive suppression of the human nucleus accumbens (nac) with transcranial focused ultrasound (tfus) modulates the reward network: a pilot study. |
2024-04-17 |
2024-04-19 |
human |
| Xiaolong Peng, Dillon J Connolly, Falon Sutton, John Robinson, Brenna Baker-Vogel, Edward B Short, Bashar W Badra. Non-invasive suppression of the human nucleus accumbens (NAc) with transcranial focused ultrasound (tFUS) modulates the reward network: a pilot study. Frontiers in human neuroscience. vol 18. 2024-04-17. PMID:38628972. |
the nucleus accumbens (nac) is a key node of the brain reward circuit driving reward-related behavior. |
2024-04-17 |
2024-04-19 |
human |
| Philipp Mews, Lucas Sosnick, Ashik Gurung, Simone Sidoli, Eric J Nestle. Decoding cocaine-induced proteomic adaptations in the mouse nucleus accumbens. Science signaling. vol 17. issue 832. 2024-04-16. PMID:38626009. |
the nucleus accumbens (nac), a region that is integral to the brain's reward circuitry, plays a crucial role in the initiation and continuation of maladaptive behaviors that are intrinsic to cud. |
2024-04-16 |
2024-04-19 |
mouse |
| Hannah F Waguespack, Jessica T Jacobs, Janis Park, Carolina Campos-Rodriguez, Rafael S Maior, Patrick A Forcelli, Ludise Malkov. Pharmacological inhibition of the nucleus accumbens increases dyadic social interaction in macaques. eNeuro. 2024-04-04. PMID:38575350. |
the nucleus accumbens (nac) is a central component of the brain circuitry that mediates motivated behavior, including reward processing. |
2024-04-04 |
2024-04-07 |
Not clear |
| Shelby Travaglianti, Ahmed Alotaibi, Woonyen Wong, Magid Abou-Gharbia, Wayne Childers, Youssef Sar. Effects of novel GLT-1 modulator, MC-100093, on neuroinflammatory and neurotrophic biomarkers in mesocorticolimbic brain regions of male alcohol preferring rats exposed chronically to ethanol. Brain research bulletin. 2024-04-03. PMID:38570076. |
chronic ethanol consumption can lead to increased extracellular glutamate concentrations in key reward brain regions, such as medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and consequently leading to oxidative stress and neuroinflammation. |
2024-04-03 |
2024-04-06 |
rat |
| Florian Schoukroun, Katia Befort, Romain Bourd. The rostromedial tegmental nucleus gates fat overconsumption through ventral tegmental area output in male rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2024-04-03. PMID:38570645. |
similar to addictive drugs, such foods activate the brain's reward circuit, involving mesolimbic dopaminergic projections from the ventral tegmental area (vta) to the nucleus accumbens (nac) and the prefrontal cortex. |
2024-04-03 |
2024-04-06 |
rat |
| Freddyson J Martínez-Rivera, Leanne M Holt, Angélica Minier-Toribio, Molly Estill, Szu-Ying Yeh, Solange Tofani, Rita Futamura, Caleb J Browne, Philipp Mews, Li Shen, Eric J Nestle. Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559084. |
cocaine use disorder (cud) exemplifies this phenomenon in which neurobiological modifications hijack brain reward regions such as the nucleus accumbens (nac) to manifest craving and withdrawal-like symptoms. |
2024-04-01 |
2024-04-04 |
rat |