| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Collin D Teague, Eric J Nestle. Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens. Molecular psychiatry. 2021-12-06. PMID:34079067. |
repeated cocaine use induces coordinated changes in gene expression that drive plasticity in the nucleus accumbens (nac), an important component of the brain's reward circuitry, and promote the development of maladaptive, addiction-like behaviors. |
2021-12-06 |
2023-08-13 |
Not clear |
| Asrin Sharifi, Saeideh Karimi-Haghighi, Ronak Shabani, Hamid Reza Asgari, Reza Ahadi, Abbas Haghparas. Cannabidiol impairs the rewarding effects of methamphetamine: Involvement of dopaminergic receptors in the nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 113. 2021-12-06. PMID:34662693. |
moreover, the nucleus accumbens (nac), as a key area in the reward circuit, extensively receives dopaminergic projections from the ventral tegmentum area. |
2021-12-06 |
2023-08-13 |
rat |
| Pinchun Wang, Jie Feng, Yajie Wang, Wenwei Zhu, Shiyu Wei, Hohjin Im, Qiang Wan. Sex-specific static and dynamic functional networks of sub-divisions of striatum linking to the greed personality trait. Neuropsychologia. vol 163. 2021-12-06. PMID:34678357. |
in this study, we explored the associations between gpt and static/dynamic reward circuit-specifically its sub-regions' functional networks including caudate, nucleus accumbens (nacc), and putamen. |
2021-12-06 |
2023-08-13 |
human |
| Jesus Pujol, Laura Blanco-Hinojo, Gerard Martínez-Vilavella, Joan Deus, Víctor Pérez-Sola, Jordi Sunye. Dysfunctional Brain Reward System in Child Obesity. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 9. 2021-12-01. PMID:33861860. |
the major components of the reward system were identified within the ventral striatum network defined on the basis of the nucleus accumbens connectivity pattern. |
2021-12-01 |
2023-08-13 |
Not clear |
| Zhiyuan Liu, Qiumin Le, Yanbo Lv, Xi Chen, Jian Cui, Yiming Zhou, Deqin Cheng, Chaonan Ma, Xiujuan Su, Lei Xiao, Ruyi Yang, Jiayi Zhang, Lan Ma, Xing Li. A distinct D1-MSN subpopulation down-regulates dopamine to promote negative emotional state. Cell research. 2021-12-01. PMID:34848869. |
dopamine (da) level in the nucleus accumbens (nac) is critical for reward and aversion encoding. |
2021-12-01 |
2023-08-13 |
Not clear |
| Alexander K Zinsmaier, Yan Dong, Yanhua H Huan. Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens. Molecular psychiatry. 2021-11-26. PMID:33963288. |
the nucleus accumbens (nac) integrates and prioritizes different emotional and motivational inputs to the reward system by processing convergent glutamatergic projections from the medial prefrontal cortex, basolateral amygdala, ventral hippocampus, and other limbic and paralimbic brain regions. |
2021-11-26 |
2023-08-13 |
Not clear |
| Philip Brandner, Berna Güroğlu, Suzanne van de Groep, Jochem P Spaans, Eveline A Cron. Happy for Us not Them: Differences in neural activation in a vicarious reward task between family and strangers during adolescent development. Developmental cognitive neuroscience. vol 51. 2021-11-25. PMID:34273748. |
a region-of-interest (roi) analysis of the nucleus accumbens revealed robust activation in this region for personal reward as well as vicarious rewards for both parents. |
2021-11-25 |
2023-08-13 |
human |
| Ryuhei Ueda, Nobuhito Ab. Neural Representations of the Committed Romantic Partner in the Nucleus Accumbens. Psychological science. 2021-11-25. PMID:34822306. |
dopamine-rich reward regions, including the nucleus accumbens (nacc), have been identified as neural correlates for both emotional bonding with the partner and interest in unfamiliar attractive nonpartners. |
2021-11-25 |
2023-08-13 |
human |
| Dirk De Ridder, Sven Vannest. The Bayesian brain in imbalance: Medial, lateral and descending pathways in tinnitus and pain: A perspective. Progress in brain research. vol 262. 2021-11-24. PMID:33931186. |
this reference resetting is confirmed by the nucleus accumbens as part of the reward system and maintained by connectivity changes between the nucleus accumbens and the pregenual anterior cingulate cortex. |
2021-11-24 |
2023-08-13 |
Not clear |
| Harrison M Fontaine, Phillip R Silva, Carlie Neiswanger, Rachelle Tran, Antony D Abraham, Benjamin B Land, John F Neumaier, Charles Chavki. Stress decreases serotonin tone in the nucleus accumbens in male mice to promote aversion and potentiate cocaine preference via decreased stimulation of 5-HT Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-24. PMID:34564712. |
stress decreases serotonin tone in the nucleus accumbens in male mice to promote aversion and potentiate cocaine preference via decreased stimulation of 5-ht stress-induced release of dynorphins (dyn) activates kappa opioid receptors (kor) in serotonergic neurons to produce dysphoria and potentiate drug reward; however, the circuit mechanisms responsible for this effect are not known. |
2021-11-24 |
2023-08-13 |
mouse |
| Carlee Toddes, Emilia M Lefevre, Dieter D Brandner, Lauryn Zugschwert, Patrick E Rothwel. μ-Opioid Receptor (Oprm1) Copy Number Influences Nucleus Accumbens Microcircuitry and Reciprocal Social Behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 38. 2021-11-23. PMID:34301826. |
the μ-opioid receptor regulates reward derived from both drug use and natural experiences, including social interaction, through actions in the nucleus accumbens. |
2021-11-23 |
2023-08-13 |
mouse |
| Marta Casquero-Veiga, Clara Bueno-Fernandez, Diego Romero-Miguel, Nicolás Lamanna-Rama, Juan Nacher, Manuel Desco, María Luisa Soto-Montenegr. Exploratory study of the long-term footprint of deep brain stimulation on brain metabolism and neuroplasticity in an animal model of obesity. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33692388. |
preclinical studies in obesity showed that the stimulation of the lateral hypothalamus (lh) and nucleus accumbens (nacc), brain centers involved in satiety and reward circuits, are able to modulate the activity of brain structures impaired in this pathology. |
2021-11-22 |
2023-08-13 |
Not clear |
| Javier Orihuel, Roberto Capellán, David Roura-Martínez, Marcos Ucha, Emilio Ambrosio, Alejandro Higuera-Mata. Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner. The international journal of neuropsychopharmacology. vol 24. issue 11. 2021-11-22. PMID:34436576. |
Δ 9-tetrahydrocannabinol during adolescence reprograms the nucleus accumbens transcriptome, affecting reward processing, impulsivity, and specific aspects of cocaine addiction-like behavior in a sex-dependent manner. |
2021-11-22 |
2023-08-13 |
Not clear |
| Yue-Ying Liu, Le Liu, Lei Zhu, Xiu Yang, Kun Tong, Yue You, Li Yang, Yin Gao, Xu Li, Di-Shi Chen, Jing-Ru Hao, Nan Sun, Can Ga. dCA1-NAc shell glutamatergic projection mediates context-induced memory recall of morphine. Pharmacological research. vol 172. 2021-11-16. PMID:34461223. |
one of the key regions of the reward is the nucleus accumbens (nac) which receives glutamatergic projections from the dorsal hippocampus ca1 (dca1). |
2021-11-16 |
2023-08-13 |
mouse |
| XiangFei Liu, JiaLing Zhou, Tian Zhang, Ken Chen, Min Xu, Lei Wu, Jin Liu, YunKe Huang, BinBin Nie, Xu Shen, Ping Ren, Xi Huan. Meranzin hydrate elicits antidepressant effects and restores reward circuitry. Behavioural brain research. vol 398. 2021-11-15. PMID:32905810. |
a literature search shown that nucleus accumbens (nac) and hypothalamus of the reward system might reveal multiple effects of mh on mdd-fd-cvd comorbidity. |
2021-11-15 |
2023-08-13 |
rat |
| Shani Gendelis, Dorrit Inbar, Yonatan M Kupchi. The role of the nucleus accumbens and ventral pallidum in feeding and obesity. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-12. PMID:34242717. |
in this review we focus on the contribution of two major interconnected structures central to reward processing, the nucleus accumbens and the ventral pallidum, to obesity. |
2021-11-12 |
2023-08-13 |
Not clear |
| S Lannoy, E V Sulliva. Trajectories of brain development reveal times of risk and factors promoting resilience to alcohol use during adolescence. International review of neurobiology. vol 160. 2021-11-11. PMID:34696880. |
for example, concurrent high dorsolateral prefrontal activation serving inhibitory control and low nucleus accumbens activation serving reward functions engender positive adaptation and low alcohol use. |
2021-11-11 |
2023-08-13 |
Not clear |
| Suchan Chang, Yu Fan, Soo Min Lee, Yeonhee Ryu, Bong Hyo Lee, Sang Chan Kim, Kyle B Bills, Scott C Steffensen, Chae Ha Yang, Hee Young Ki. Acupuncture reduces cocaine psychomotor responses by activating the rostromedial tegmental nucleus. Addiction biology. vol 26. issue 6. 2021-11-10. PMID:33969586. |
while previous studies have demonstrated that acupuncture modulates da transmission in the mesolimbic reward system originating in the ventral tegmental area (vta) and projecting to the nucleus accumbens (nac) and can reduce drug self-administration, the central links between peripheral acupuncture signals and brain reward systems are not well-characterized. |
2021-11-10 |
2023-08-13 |
Not clear |
| Xian Zhang, Wuqiang Guan, Tao Yang, Alessandro Furlan, Xiong Xiao, Kai Yu, Xu An, William Galbavy, Charu Ramakrishnan, Karl Deisseroth, Kimberly Ritola, Adam Hantman, Miao He, Z Josh Huang, Bo L. Genetically identified amygdala-striatal circuits for valence-specific behaviors. Nature neuroscience. vol 24. issue 11. 2021-11-10. PMID:34663958. |
notably, these two classes of neurons receive inputs from separate sets of sensory and limbic areas, and convey punishment and reward information through projections to the nucleus accumbens and olfactory tubercle, respectively, to drive negative and positive reinforcement. |
2021-11-10 |
2023-08-13 |
mouse |
| Loreto S San Martin, Lorena Armijo-Weingart, Anibal Araya, Gonzalo E Yévenes, Robert J Harvey, Luis G Aguay. Contribution of GlyR α3 Subunits to the Sensitivity and Effect of Ethanol in the Nucleus Accumbens. Frontiers in molecular neuroscience. vol 14. 2021-11-10. PMID:34744627. |
recent data from several laboratories have shown that glyrs are expressed in the brain reward circuitry and that α1 and α2 are the principal subunits expressed in the nucleus accumbens (nac). |
2021-11-10 |
2023-08-13 |
Not clear |