| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amanda G Iglesias, Shelly B Flage. The Paraventricular Thalamus as a Critical Node of Motivated Behavior Frontiers in integrative neuroscience. vol 15. 2021-07-06. PMID:34220458. |
based on data that has emerged in recent years, including that from our laboratory, we posit that orexinergic (ox) innervation from the lateral hypothalamus (lh) to the pvt encodes the incentive motivational value of reward cues and thereby alters the signaling of the glutamatergic neurons projecting from the pvt to the shell of the nucleus accumbens (nacsh). |
2021-07-06 |
2023-08-13 |
Not clear |
| David de Sa Nogueira, Romain Bourdy, Dominique Filliol, Gaëlle Awad, Virginie Andry, Yannick Goumon, Mary C Olmstead, Katia Befor. Binge sucrose-induced neuroadaptations: A focus on the endocannabinoid system. Appetite. vol 164. 2021-06-28. PMID:33864862. |
importantly, this group also exhibited alterations in ecs transcripts and endocannabinoid levels in brain reward regions, including an increase in cannabinoid receptor 1 (cb1r) mrna in the nucleus accumbens as well as changes in endocannabinoid levels in the prefrontal cortex and hippocampus. |
2021-06-28 |
2023-08-13 |
rat |
| T C Peixoto, E G Moura, P N Soares, V S T Rodrigues, S Claudio-Neto, E Oliveira, A C Manhães, P C Lisbo. Nicotine exposure during lactation causes disruption of hedonic eating behavior and alters dopaminergic system in adult female rats. Appetite. vol 160. 2021-06-24. PMID:33453337. |
nicotine is transferred through milk and alters the dopaminergic reward system of adult male rats, reducing dopamine action in the nucleus accumbens (nac) and hypothalamic arcuate nucleus. |
2021-06-24 |
2023-08-13 |
rat |
| S Gallegos, L San Martin, A Araya, D M Lovinger, G E Homanics, L G Aguay. Reduced sedation and increased ethanol consumption in knock-in mice expressing an ethanol insensitive alpha 2 subunit of the glycine receptor. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 3. 2021-06-23. PMID:32357359. |
previous studies have shown the presence of several subunits of the inhibitory glycine receptor (glyr) in the reward system, specifically in medium spiny neurons (msns) of the nucleus accumbens (nac). |
2021-06-23 |
2023-08-13 |
mouse |
| Milena Radoman, Natania A Crane, Stephanie M Gorka, Jessica Weafer, Scott A Langenecker, Harriet de Wit, K Luan Pha. Striatal activation to monetary reward is associated with alcohol reward sensitivity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32505126. |
participants who reported greater motivation (i.e., wanting) to consume more alcohol after a single moderate dose of alcohol also exhibited greater neural activation in the bilateral ventral caudate and the nucleus accumbens during reward receipt relative to loss. |
2021-06-23 |
2023-08-13 |
human |
| Ludivine Canchy, Paul Girardeau, Audrey Durand, Caroline Vouillac-Mendoza, Serge H Ahme. Pharmacokinetics trumps pharmacodynamics during cocaine choice: a reconciliation with the dopamine hypothesis of addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:32731253. |
first, a systematic literature analysis revealed that the delays of effects of intravenous cocaine on nucleus accumbens dopamine are of the order of tens of seconds and are considerably longer than those of nondrug reward. |
2021-06-23 |
2023-08-13 |
rat |
| Inge Volman, Abbie Pringle, Lennart Verhagen, Michael Browning, Phil J Cowen, Catherine J Harme. Lithium modulates striatal reward anticipation and prediction error coding in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:33127993. |
the monetary incentive delay task is a robust task with excellent test-retest reliability and is well suited to investigate different phases of reward processing within the caudate and nucleus accumbens. |
2021-06-23 |
2023-08-13 |
human |
| Inge Volman, Abbie Pringle, Lennart Verhagen, Michael Browning, Phil J Cowen, Catherine J Harme. Lithium modulates striatal reward anticipation and prediction error coding in healthy volunteers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 2. 2021-06-23. PMID:33127993. |
in contrast, lithium administration reduced caudate and nucleus accumbens activity during reward outcome. |
2021-06-23 |
2023-08-13 |
human |
| Adina S Fischer, Bailey Holt-Gosselin, Scott L Fleming, Laura M Hack, Tali M Ball, Alan F Schatzberg, Leanne M William. Intrinsic reward circuit connectivity profiles underlying symptom and quality of life outcomes following antidepressant medication: a report from the iSPOT-D trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 46. issue 4. 2021-06-23. PMID:33230268. |
we quantified functional connectivity (fc) of reward neurocircuitry using nucleus accumbens (nac) seed regions of interest, and then characterized how changes in fc relate to symptom response (primary outcome) and qol response (secondary outcome). |
2021-06-23 |
2023-08-13 |
Not clear |
| Kenneth D Car. Homeostatic regulation of reward via synaptic insertion of calcium-permeable AMPA receptors in nucleus accumbens. Physiology & behavior. vol 219. 2021-06-21. PMID:32092445. |
homeostatic regulation of reward via synaptic insertion of calcium-permeable ampa receptors in nucleus accumbens. |
2021-06-21 |
2023-08-13 |
human |
| Mayank Aggarwal, Yumiko Akamine, Andrew W Liu, Jeffery R Wicken. The nucleus accumbens and inhibition in the ventral tegmental area play a causal role in the Kamin blocking effect. The European journal of neuroscience. vol 52. issue 3. 2021-06-21. PMID:32250479. |
this indicates that learning in the nucleus accumbens is necessary for blocking and reward estimation. |
2021-06-21 |
2023-08-13 |
rat |
| Ella Gabitov, Ovidiu Lungu, Geneviève Albouy, Julien Doyo. Movement errors during skilled motor performance engage distinct prediction error mechanisms. Communications biology. vol 3. issue 1. 2021-06-21. PMID:33311566. |
here we demonstrate, with functional magnetic resonance imaging, that internal detection, i.e., without externally-provided feedback, of self-generated movement errors evokes instantaneous activity increases within the salience network and delayed lingering decreases within the nucleus accumbens - a key structure in the reward valuation pathway. |
2021-06-21 |
2023-08-13 |
Not clear |
| Leanna M Hernandez, Katherine E Lawrence, N Tanya Padgaonkar, Marisa Inada, Jackson N Hoekstra, Jennifer K Lowe, Jeffrey Eilbott, Allison Jack, Elizabeth Aylward, Nadine Gaab, John D Van Horn, Raphael A Bernier, James C McPartland, Sara J Webb, Kevin A Pelphrey, Shulamite A Green, Daniel H Geschwind, Susan Y Bookheimer, Mirella Daprett. Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32127526. |
females with asd who carried a greater number of asd-associated risk alleles in the oxtr gene showed greater functional connectivity between the nucleus accumbens (nacc; hub of the reward network) and subcortical brain areas important for motor learning. |
2021-06-18 |
2023-08-13 |
Not clear |
| Deepak Chouhan, Ankit Uniyal, Anagha Gadepalli, Akhilesh, Vineeta Tiwari, Somesh Agrawal, Tapas Kumar Roy, Sneha Shaw, Narendra Purohit, Vinod Tiwar. Probing the Manipulated Neurochemical Drive in Alcohol Addiction and Novel Therapeutic Advancements. ACS chemical neuroscience. vol 11. issue 9. 2021-06-18. PMID:32243128. |
these changes occur in various regions of the brain including reward circuit such as the ventral tegmental area (vta), nucleus accumbens (nac), and prefrontal cortex. |
2021-06-18 |
2023-08-13 |
Not clear |
| Vivien Csikós, Petra Varró, Veronika Bódi, Szilvia Oláh, Ildikó Világi, Arpád Doboly. The mycotoxin deoxynivalenol activates GABAergic neurons in the reward system and inhibits feeding and maternal behaviours. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32472169. |
don injection resulted in profound c-fos activation in only the elements of the reward system, such as the accumbens nucleus, the medial prefrontal cortex, and the ventral tegmental area. |
2021-06-16 |
2023-08-13 |
mouse |
| Tracy L Fetterly, Max F Oginsky, Allison M Nieto, Yanaira Alonso-Caraballo, Zuleirys Santana-Rodriguez, Carrie R Ferrari. Insulin Bidirectionally Alters NAc Glutamatergic Transmission: Interactions between Insulin Receptor Activation, Endogenous Opioids, and Glutamate Release. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 11. 2021-06-11. PMID:33514676. |
human fmri studies show that insulin influences brain activity in regions that mediate reward and motivation, including the nucleus accumbens (nac). |
2021-06-11 |
2023-08-13 |
human |
| Hassan Jorjani, Marzieh Joneidi, Abbas Ali Vafaei, Ali Rashidy-Pour, Hamidreza Sameni, Ahmad Reza Bandegi, Behpour Yousefi, Hossein Miladi-Gorj. Corrigendum to "Microinjection of the BDNF receptor antagonist ANA-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of BDNF levels and apoptotic cells in rats" [Pharmacol. Biochem. Behav. 201 (2021) 173111]. Pharmacology, biochemistry, and behavior. vol 203. 2021-06-11. PMID:33601109. |
corrigendum to "microinjection of the bdnf receptor antagonist ana-12 into the nucleus accumbens and medial-prefrontal cortex attenuates morphine-induced reward memory, and alterations of bdnf levels and apoptotic cells in rats" [pharmacol. |
2021-06-11 |
2023-08-13 |
rat |
| Elahe Khosrowabadi, Saeideh Karimi-Haghighi, Shole Jamali, Abbas Haghparas. Differential Roles of Intra-accumbal Orexin Receptors in Acquisition and Expression of Methamphetamine-Induced Conditioned Place Preference in the Rats. Neurochemical research. vol 45. issue 9. 2021-06-08. PMID:32643036. |
a large amount of document has revealed that the orexin system in the reward circuity, including the nucleus accumbens (nac), contributes to the modification of drug reinforcement. |
2021-06-08 |
2023-08-13 |
rat |
| Pamela DeRosse, Anita D Barbe. Overlapping Neurobiological Substrates for Early-Life Stress and Resilience to Psychosis. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 2. 2021-06-03. PMID:33097471. |
exposure to early-life stress disrupts the neurodevelopment of widespread brain systems, including key components of the hypothalamic-pituitary-adrenal axis stress response, such as the amygdala, hippocampus, and medial prefrontal cortex, as well as key components of the brain's reward system, such as the nucleus accumbens and orbitofrontal cortex. |
2021-06-03 |
2023-08-13 |
Not clear |
| Marlou P Lasschuijt, Kees de Graaf, Monica Mar. Effects of Oro-Sensory Exposure on Satiation and Underlying Neurophysiological Mechanisms-What Do We Know So Far? Nutrients. vol 13. issue 5. 2021-05-26. PMID:33919044. |
oro-sensory exposure to food affects satiation by direct signaling via the brainstem to higher cortical regions involved in taste and reward, including the nucleus accumbens and the insula. |
2021-05-26 |
2023-08-13 |
Not clear |