| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jamie L Hanson, Alexia V Williams, Debra A Bangasser, Catherine J Peñ. Impact of Early Life Stress on Reward Circuit Function and Regulation. Frontiers in psychiatry. vol 12. 2021-11-10. PMID:34744836. |
a major component of this risk may be early life stress-induced alterations in motivation and reward processing, mediated by changes in the nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-11-10 |
2023-08-13 |
human |
| Kara M Wendel, Annabel K Short, Brenda P Noarbe, Elizabeth Haddad, Anton M Palma, Michael A Yassa, Tallie Z Baram, Andre Obenau. Early life adversity in male mice sculpts reward circuits. Neurobiology of stress. vol 15. 2021-11-10. PMID:34746338. |
in this study, we focused on the projections from the dorsal raphe (dr) to the ventral tegmental area (vta) and on to the nucleus accumbens (nacc), an important pathway within the reward circuit. |
2021-11-10 |
2023-08-13 |
mouse |
| Michał Sobstyl, Anna Kupryjaniuk, Paweł Mierzejewsk. Nucleus accumbens as a stereotactic target for the treatment of addictions in humans: a literature review. Neurologia i neurochirurgia polska. vol 55. issue 5. 2021-11-09. PMID:34633060. |
more recently, a limited number of basic and clinical studies have indicated that dbs of the nucleus accumbens (nac) and other neighbouring structures of the reward circuit may be an effective intervention for patients with treatment-refractory addiction. |
2021-11-09 |
2023-08-13 |
Not clear |
| Akira Mizoguchi, Ryoichi Banno, Runan Sun, Hiroshi Yaginuma, Keigo Taki, Tomoko Kobayashi, Mariko Sugiyama, Taku Tsunekawa, Takeshi Onoue, Hiroshi Takagi, Daisuke Hagiwara, Yoshihiro Ito, Shintaro Iwama, Hidetaka Suga, Taku Nagai, Kiyofumi Yamada, Hiroshi Arim. Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice. Scientific reports. vol 11. issue 1. 2021-11-05. PMID:34145364. |
the reward system, which consists of dopaminergic neurons projecting from the ventral tegmental area (vta) to the nucleus accumbens and caudate-putamen in the striatum, has an important role in the pathogenesis of not only drug addiction but also diet-induced obesity. |
2021-11-05 |
2023-08-13 |
mouse |
| Richard Quansah Amissah, Diellor Basha, Olga Bukhtiyarova, Elena Timofeeva, Igor Timofee. Neuronal activities during palatable food consumption in the reward system of binge-like eating female rats. Physiology & behavior. vol 242. 2021-11-03. PMID:34563545. |
in humans, bed is associated with desensitization of the reward system, specifically, the medial prefrontal cortex (mpfc), nucleus accumbens (acb), and ventral tegmental area (vta). |
2021-11-03 |
2023-08-13 |
rat |
| Nanette Y Schneider, Sylvie Chaudy, Alberto L Epstein, Cécile Viollet, Alexandre Benani, Luc Pénicaud, Xavier Grosmaître, Frédérique Datiche, Jean Gascue. Centrifugal projections to the main olfactory bulb revealed by transsynaptic retrograde tracing in mice. The Journal of comparative neurology. vol 528. issue 11. 2021-11-02. PMID:31872441. |
other indirect projections have been evidenced in areas of the reward circuit such as vta and accumbens nucleus. |
2021-11-02 |
2023-08-13 |
mouse |
| Casey K Lardner, Yentl van der Zee, Molly S Estill, Hope G Kronman, Marine Salery, Ashley M Cunningham, Arthur Godino, Eric M Parise, Jee Hyun Kim, Rachael L Neve, Li Shen, Peter J Hamilton, Eric J Nestle. Gene-Targeted, CREB-Mediated Induction of ΔFosB Controls Distinct Downstream Transcriptional Patterns Within D1 and D2 Medium Spiny Neurons. Biological psychiatry. vol 90. issue 8. 2021-11-01. PMID:34425966. |
Δfosb is a transcription factor that accumulates in the nucleus accumbens (nac)-a brain region responsible for coordinating reward and motivation-after exposure to virtually every known rewarding substance, including cocaine and opioids. |
2021-11-01 |
2023-08-13 |
Not clear |
| Tiago Bortolini, Bruno Melo, Rodrigo Basilio, Ronald Fischer, Roland Zahn, Ricardo de Oliveira-Souza, Brian Knutson, Jorge Mol. Striatal and septo-hypothalamic responses to anticipation and outcome of affiliative rewards. NeuroImage. vol 243. 2021-10-29. PMID:34407439. |
here, we interrogate the role of the critical reward circuitry, especially the nucleus accumbens (nacc) and the septo-hypothalamic region, in the anticipation of and response to affiliative rewards using a novel incentive delay task. |
2021-10-29 |
2023-08-13 |
human |
| Bowen Geng, Ming Gao, Jiayu Wu, Chengxiang Liu, Ruiqing Piao, Guang Yang, Xiao Zeng, Peng Li. Functional Connectivity of Nucleus Accumbens Is Associated with Lifelong Premature Ejaculation in Male Adults : A Resting-state fMRI Study. Clinical neuroradiology. 2021-10-29. PMID:34714363. |
ejaculation represents a crucial component of sexual behavior in men, which is involved in reward functions of certain brain areas including the nucleus accumbens (nacc). |
2021-10-29 |
2023-08-13 |
Not clear |
| Rahmi Elibol, Neslihan Serap Şengö. Modeling nucleus accumbens : A Computational Model from Single Cell to Circuit Level. Journal of computational neuroscience. vol 49. issue 1. 2021-10-28. PMID:33165797. |
nucleus accumbens is part of the neural structures required for reward based learning and cognitive processing of motivation. |
2021-10-28 |
2023-08-13 |
Not clear |
| Felix P Mayer, Hideki Iwamoto, Maureen K Hahn, Gregory J Grumbar, Adele Stewart, Yulong Li, Randy D Blakel. There's no place like home? Return to the home cage triggers dopamine release in the mouse nucleus accumbens. Neurochemistry international. vol 142. 2021-10-27. PMID:33161093. |
various stimuli have been employed as reinforcers in preclinical rodent models to elucidate the underpinnings of reward at a molecular and circuit level, with the release of dopamine (da) in the nucleus accumbens (nac) as a well-replicated, physiological correlate. |
2021-10-27 |
2023-08-13 |
mouse |
| Molly Estill, Efrain Ribeiro, Nancy J Francoeur, Melissa L Smith, Robert Sebra, Szu-Ying Yeh, Ashley M Cunningham, Eric J Nestler, Li She. Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment. Scientific reports. vol 11. issue 1. 2021-10-25. PMID:33762610. |
to better understand the full-length transcriptome of the nucleus accumbens (nac)-a key brain reward region-in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the iso-seq method to detect 42,114 unique transcripts from mouse nac polyadenylated rna. |
2021-10-25 |
2023-08-13 |
mouse |
| Martyna Bayassi-Jakowicka, Grazyna Lietzau, Ewelina Czuba, Aleksandra Steliga, Monika Waśkow, Przemysław Kowiańsk. Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System. International journal of molecular sciences. vol 22. issue 18. 2021-10-22. PMID:34575969. |
neuroplasticity and multilevel system of connections determine the integrative role of nucleus accumbens in the brain reward system. |
2021-10-22 |
2023-08-13 |
Not clear |
| Martyna Bayassi-Jakowicka, Grazyna Lietzau, Ewelina Czuba, Aleksandra Steliga, Monika Waśkow, Przemysław Kowiańsk. Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System. International journal of molecular sciences. vol 22. issue 18. 2021-10-22. PMID:34575969. |
a growing body of evidence suggests that nucleus accumbens (nac) plays a significant role not only in the physiological processes associated with reward and satisfaction but also in many diseases of the central nervous system. |
2021-10-22 |
2023-08-13 |
Not clear |
| Y Sar. Potential therapeutic role of glutamate transporter 1 for the treatment of alcohol dependence. OA alcohol. vol 1. issue 1. 2021-10-21. PMID:24409344. |
alcohol-seeking behaviour is promoted by increased glutamate transmission in key regions of the mesocorticolimbic reward circuit, including the nucleus accumbens and prefrontal cortex. |
2021-10-21 |
2023-08-12 |
human |
| Alyse N Maksimoski, Brandon J Polzin, Sharon A Stevenson, Changjiu Zhao, Lauren V Riter. μ-Opioid Receptor Stimulation in the Nucleus Accumbens Increases Vocal-Social Interactions in Flocking European Starlings, eNeuro. vol 8. issue 5. 2021-10-20. PMID:34475266. |
the μ-opioid receptors (mors) in the nucleus accumbens (nac) are well known for their role in both reward and the reduction of negative affective states, suggesting that mor stimulation in nac may play a critical role in flock cohesion. |
2021-10-20 |
2023-08-13 |
Not clear |
| Ann F Haynos, Jazmin Camchong, Carolyn M Pearson, Jason M Lavender, Bryon A Mueller, Carol B Peterson, Sheila Specker, Nancy Raymond, Kelvin O Li. Resting State Hypoconnectivity of Reward Networks in Binge Eating Disorder. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 5. 2021-10-15. PMID:33415334. |
a seed-based approach was employed to examine the resting state functional connectivity (rsfc) of the striatum (nucleus accumbens [nacc] and ventral and dorsal caudate), a collection of regions implicated in reward processing. |
2021-10-15 |
2023-08-13 |
Not clear |
| L M Molina-Martínez, J Juáre. Deficit of β-endorphin neurons in the hypothalamus and high expression of MOR in mesolimbic structures are related to high alcohol consumption in outbred rats. Alcohol (Fayetteville, N.Y.). vol 95. 2021-10-15. PMID:34022405. |
we analyzed the number of β-endorphin-positive neurons in the arcuate nucleus (arn) and the expression of μ-opioid receptors (mor) in regions of the reward system, such as the nucleus accumbens (nac), amygdala (amy), and ventral tegmental area (vta) in outbred rats with low (lc) or high (hc) voluntary alcohol consumption. |
2021-10-15 |
2023-08-13 |
rat |
| Shole Jamali, Shahram Zarrabian, Abbas Haghparas. Similar role of mPFC orexin-1 receptors in the acquisition and expression of morphine- and food-induced conditioned place preference in male rats. Neuropharmacology. vol 198. 2021-10-14. PMID:34450116. |
different brain areas are involved in natural and drug reward processing including the mesolimbic pathway, amygdala, nucleus accumbens (nac), and prefrontal cortex. |
2021-10-14 |
2023-08-13 |
rat |
| Sarah J Alger, Sharon A Stevenson, Ana Armenta Vega, Cynthia A Kelm-Nelson, Charity Vilchez Juang, Lauren V Riter. Differences in dopamine and opioid receptor ratios in the nucleus accumbens relate to physical contact and undirected song in pair-bonded zebra finches. Behavioral neuroscience. 2021-10-11. PMID:34618494. |
dopamine and opioids in the nucleus accumbens (nac) alter motivational state and reward by binding to receptor subtypes that engage distinct and opposing second messenger systems, and there is evidence that receptor ratios may influence social behavior. |
2021-10-11 |
2023-08-13 |
Not clear |