| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Zhu, Feifei Wu, Zhilan Yan, Lijun He, Shufei Wang, Haohao Hu, Eyleen L K Goh, Yingjie Zhu, Fanglin Guan, Teng Che. A novel microRNA, novel-m009C, regulates methamphetamine rewarding effects. Molecular psychiatry. 2022-06-17. PMID:35715487. |
our findings demonstrate an important role for nac novel-m009c in regulating meth reward, reveal a novel molecular regulator of the actions of meth on brain reward circuitries and provide a new strategy for treating meth addiction based on the modulation of small non-coding rnas. |
2022-06-17 |
2023-08-14 |
mouse |
| Sophia C Levis, Matthew T Birnie, Jessica L Bolton, Christina R Perrone, Johanna S Montesinos, Tallie Z Baram, Stephen V Mahle. Enduring disruption of reward and stress circuit activities by early-life adversity in male rats. Translational psychiatry. vol 12. issue 1. 2022-06-15. PMID:35705547. |
we probe potential circuit mechanisms in males by assessing opioid-associated neuronal activation in stress and reward circuit nodes including nucleus accumbens (nac), amygdala, medial prefrontal cortex (mpfc), and paraventricular thalamus. |
2022-06-15 |
2023-08-14 |
rat |
| Yu-Dan Ding, Xiao Chen, Zuo-Bing Chen, Le Li, Xue-Ying Li, Francisco Xavier Castellanos, Tong-Jian Bai, Qi-Jing Bo, Jun Cao, Zhi-Kai Chang, Guan-Mao Chen, Ning-Xuan Chen, Wei Chen, Chang Cheng, Yu-Qi Cheng, Xi-Long Cui, Jia Duan, Yi-Ru Fang, Qi-Yong Gong, Zheng-Hua Hou, Lan Hu, Li Kuang, Feng Li, Hui-Xian Li, Kai-Ming Li, Tao Li, Yan-Song Liu, Zhe-Ning Liu, Yi-Cheng Long, Bin Lu, Qing-Hua Luo, Hua-Qing Meng, Dai-Hui Peng, Hai-Tang Qiu, Jiang Qiu, Yue-Di Shen, Yu-Shu Shi, Tian-Mei Si, Yan-Qing Tang, Chuan-Yue Wang, Fei Wang, Kai Wang, Li Wang, Xiang Wang, Ying Wang, Yu-Wei Wang, Xiao-Ping Wu, Xin-Ran Wu, Chun-Ming Xie, Guang-Rong Xie, Hai-Yan Xie, Peng Xie, Xiu-Feng Xu, Hong Yang, Jian Yang, Jia-Shu Yao, Shu-Qiao Yao, Ying-Ying Yin, Yong-Gui Yuan, Yu-Feng Zang, Ai-Xia Zhang, Hong Zhang, Ke-Rang Zhang, Lei Zhang, Zhi-Jun Zhang, Jing-Ping Zhao, Ru-Bai Zhou, Yi-Ting Zhou, Jun-Juan Zhu, Zhi-Chen Zhu, Chao-Jie Zou, Xi-Nian Zuo, Chao-Gan Yan, Wen-Bin Gu. Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder. Translational psychiatry. vol 12. issue 1. 2022-06-06. PMID:35668086. |
the nucleus accumbens (nac) is considered a hub of reward processing and a growing body of evidence has suggested its crucial role in the pathophysiology of major depressive disorder (mdd). |
2022-06-06 |
2023-08-14 |
Not clear |
| Yu-Dan Ding, Xiao Chen, Zuo-Bing Chen, Le Li, Xue-Ying Li, Francisco Xavier Castellanos, Tong-Jian Bai, Qi-Jing Bo, Jun Cao, Zhi-Kai Chang, Guan-Mao Chen, Ning-Xuan Chen, Wei Chen, Chang Cheng, Yu-Qi Cheng, Xi-Long Cui, Jia Duan, Yi-Ru Fang, Qi-Yong Gong, Zheng-Hua Hou, Lan Hu, Li Kuang, Feng Li, Hui-Xian Li, Kai-Ming Li, Tao Li, Yan-Song Liu, Zhe-Ning Liu, Yi-Cheng Long, Bin Lu, Qing-Hua Luo, Hua-Qing Meng, Dai-Hui Peng, Hai-Tang Qiu, Jiang Qiu, Yue-Di Shen, Yu-Shu Shi, Tian-Mei Si, Yan-Qing Tang, Chuan-Yue Wang, Fei Wang, Kai Wang, Li Wang, Xiang Wang, Ying Wang, Yu-Wei Wang, Xiao-Ping Wu, Xin-Ran Wu, Chun-Ming Xie, Guang-Rong Xie, Hai-Yan Xie, Peng Xie, Xiu-Feng Xu, Hong Yang, Jian Yang, Jia-Shu Yao, Shu-Qiao Yao, Ying-Ying Yin, Yong-Gui Yuan, Yu-Feng Zang, Ai-Xia Zhang, Hong Zhang, Ke-Rang Zhang, Lei Zhang, Zhi-Jun Zhang, Jing-Ping Zhao, Ru-Bai Zhou, Yi-Ting Zhou, Jun-Juan Zhu, Zhi-Chen Zhu, Chao-Jie Zou, Xi-Nian Zuo, Chao-Gan Yan, Wen-Bin Gu. Reduced nucleus accumbens functional connectivity in reward network and default mode network in patients with recurrent major depressive disorder. Translational psychiatry. vol 12. issue 1. 2022-06-06. PMID:35668086. |
specifically, the combination of disrupted nac fcs within the reward network could discriminate patients with recurrent mdd from healthy controls with an optimal accuracy of 74.7%. |
2022-06-06 |
2023-08-14 |
Not clear |
| Xin Wang, Fei Li, Jun Zhu, Dayun Feng, Yingwu Shi, Liang Qu, Yang Li, Kang Guo, Yue Zhang, Qiang Wang, Naigeng Wang, Xuelian Wang, Shunnan G. Upregulation of Cell Division Cycle 20 Expression Alters the Morphology of Neuronal Dendritic Spines in the Nucleus Accumbens by Promoting FMRP Ubiquitination. Journal of neurochemistry. 2022-05-27. PMID:35621027. |
the nucleus accumbens (nac) is the key area of the reward circuit, but its heterogeneity has been poorly studied. |
2022-05-27 |
2023-08-13 |
rat |
| Bingqian Zhou, Yuan Chen, Ruiping Zheng, Yu Jiang, Shuying Li, Yarui Wei, MengZhe Zhang, XinYu Gao, Baohong Wen, Shaoqiang Han, Jingliang Chen. Alterations of Static and Dynamic Functional Connectivity of the Nucleus Accumbens in Patients With Major Depressive Disorder. Frontiers in psychiatry. vol 13. 2022-05-26. PMID:35615457. |
as an important node in the reward system, the resting-state functional connectivity of the nucleus accumbens (nac) is related to the etiology of mdd. |
2022-05-26 |
2023-08-13 |
Not clear |
| Tomasz Gos, Johann Steiner, Kurt Trübner, Marta Krzyżanowska, Michał Kalisza. Ribosomal DNA transcription is increased in the left nucleus accumbens of heroin-dependent males. European archives of psychiatry and clinical neuroscience. 2022-05-14. PMID:35567616. |
the nucleus accumbens (nac) plays an outstanding neurobiological role in opioid addiction as a part of the striatum and key component of brain reward system. |
2022-05-14 |
2023-08-13 |
human |
| Chelsea Brown, Jackie Beltran, Elissa Fultz, Tori Tran, Brooke Barger, Nyssa Williams, Waylon Yen, Asher Park, Tod Kippin, Karen Szumlinsk. Investigating the Role of Corticostriatal Glutamate Signaling in Methamphetamine Reward and Reinforcement. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554032. |
while the majority of addiction research has implicated the dopamine system, the long-term neuroplasticity that maintains ma use disorder also involves drug-induced changes in glutamate signaling in reward regions of the brain like the nucleus accumbens (nac) and prefrontal cortex (pfc). |
2022-05-13 |
2023-08-13 |
Not clear |
| Chelsea Brown, Jackie Beltran, Elissa Fultz, Tori Tran, Brooke Barger, Nyssa Williams, Waylon Yen, Asher Park, Tod Kippin, Karen Szumlinsk. Investigating the Role of Corticostriatal Glutamate Signaling in Methamphetamine Reward and Reinforcement. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554032. |
in order to further characterize the role of glutamate in ma reward and reinforcement, glutamate receptor scaffolding protein homer2 expression in the nac and activity in the glutamatergic projection pfc-nac were manipulated prior to place- and operant-conditioning procedures. |
2022-05-13 |
2023-08-13 |
Not clear |
| Kimberly Thibeault, Alberto Lopez, Joseph Dryer, Veronika Kondev, Sachin Patel, Cody Siciliano, Erin Calipar. Characterizing the transcriptionally-activated ensembles recruited by cocaine in the nucleus accumbens. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554570. |
here we aimed to determine if ensembles transcriptionally activated by cocaine in the nucleus accumbens (nac) - a brain region central to reward encoding - were capable of driving motivated behaviors in isolation. |
2022-05-13 |
2023-08-13 |
mouse |
| Dennis A Burke, Veronica A Alvare. Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports. vol 39. issue 6. 2022-05-11. PMID:35545050. |
dopamine modulation of nucleus accumbens (nac) circuitry is central to theories of reward seeking and reinforcement learning. |
2022-05-11 |
2023-08-13 |
mouse |
| Hannah M Baumgartner, Madeliene Granillo, Jay Schulkin, Kent C Berridg. Corticotropin releasing factor (CRF) systems: Promoting cocaine pursuit without distress via incentive motivation. PloS one. vol 17. issue 5. 2022-05-03. PMID:35503756. |
here we tested whether optogenetic excitation of crf-containing neurons in either nac medial shell, lateral cea, or dorsolateral bnst of transgenic crh-cre+ rats would spur preference and pursuit of a particular laser-paired cocaine reward over an alternative cocaine reward, and whether excitation served as a positively-valenced incentive itself, through laser self-stimulation tests. |
2022-05-03 |
2023-08-13 |
rat |
| Hannah M Baumgartner, Madeliene Granillo, Jay Schulkin, Kent C Berridg. Corticotropin releasing factor (CRF) systems: Promoting cocaine pursuit without distress via incentive motivation. PloS one. vol 17. issue 5. 2022-05-03. PMID:35503756. |
we report that excitation of crf-containing neurons in either nac or cea recruited mesocorticolimbic circuitry to amplify incentive motivation to pursue the laser-paired cocaine: focusing preference on the laser-paired cocaine reward in a two-choice task, and spurred pursuit as doubled breakpoint in a progressive ratio task. |
2022-05-03 |
2023-08-13 |
rat |
| Joshua P Stamos, Sisi Ma, Anthony P Pawlak, Nofar Engelhard, Jon C Horvitz, Mark O Wes. Reward vs. motoric activations in Nucleus Accumbens Core of rats during pavlovian conditioning. The European journal of neuroscience. 2022-05-01. PMID:35491443. |
the nucleus accumbens (nac) core plays an important role in processing of events related to food reward, such as conditioned cues, approach, or consumption. |
2022-05-01 |
2023-08-13 |
rat |
| Jimmie M Gmaz, Matthijs A A van der Mee. Context coding in the mouse nucleus accumbens modulates motivationally relevant information. PLoS biology. vol 20. issue 4. 2022-04-29. PMID:35486662. |
neural activity in the nucleus accumbens (nac) is thought to track fundamentally value-centric quantities linked to reward and effort. |
2022-04-29 |
2023-08-13 |
mouse |
| Rui Chang, Jionghong Peng, Yunfan Chen, Hailin Liao, Size Zhao, Ju Zou, Sijie Ta. Deep Brain Stimulation in Drug Addiction Treatment: Research Progress and Perspective. Frontiers in psychiatry. vol 13. 2022-04-25. PMID:35463506. |
addiction is characterized by neuroplastic changes in the nucleus accumbens (nac), a key structure in the brain reward system, and dbs in this region has shown promising treatment effects. |
2022-04-25 |
2023-08-13 |
Not clear |
| Darius D Becker-Krail, Kyle D Ketchesin, Jennifer N Burns, Wei Zong, Mariah A Hildebrand, Lauren M DePoy, Chelsea A Vadnie, George C Tseng, Ryan W Logan, Yanhua H Huang, Colleen A McClun. Astrocyte Molecular Clock Function in the Nucleus Accumbens Is Important for Reward-Related Behavior. Biological psychiatry. 2022-04-24. PMID:35461698. |
however, no studies to date have identified the role of circadian astrocyte function in the nucleus accumbens (nac), a hub for reward regulation, or determined the importance of these rhythms for reward-related behavior. |
2022-04-24 |
2023-08-13 |
human |
| Beatriz de la Puente, Daniel Zamanillo, Luz Romero, Alicia Carceller, José Miguel Vela, Manuel Merlos, Enrique Portillo-Salid. Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma-1 Receptor. ACS pharmacology & translational science. vol 5. issue 4. 2022-04-18. PMID:35434530. |
we explored a putative chronic pain-induced dysregulation of monoamine function by measuring monoamine levels in the nucleus accumbens (nac), a well-known brain reward area. |
2022-04-18 |
2023-08-13 |
mouse |
| Shi Yu Chan, Zi Yan Ong, Zhen Ming Ngoh, Yap Seng Chong, Juan H Zhou, Marielle V Fortier, Lourdes M Daniel, Anqi Qiu, Michael J Meaney, Ai Peng Ta. Structure-function coupling within the reward network in preschool children predicts executive functioning in later childhood. Developmental cognitive neuroscience. vol 55. 2022-04-12. PMID:35413663. |
the nucleus accumbens (nac) and orbitofrontal cortex (ofc) are activated by reward-related tasks and identified as key nodes of the brain circuit that underlie reward processing. |
2022-04-12 |
2023-08-13 |
Not clear |
| Xiaohua Cao, Qiang Li, Sha Liu, Zexuan Li, Yanfang Wang, Long Cheng, Chengxiang Yang, Yong X. Enhanced Resting-State Functional Connectivity of the Nucleus Accumbens in First-Episode, Medication-Naïve Patients With Early Onset Schizophrenia. Frontiers in neuroscience. vol 16. 2022-04-11. PMID:35401094. |
the results suggest disturbed relationships between regions subserving reward, salience processing, and regions subserving sensory processing as well as cognitive functions, which may deepen our understanding of the role of nac in the pathology of eos. |
2022-04-11 |
2023-08-13 |
Not clear |