| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert T Matthews, Olusegun Coker, Danny G Winde. A novel mouse brain slice preparation of the hippocampo-accumbens pathway. Journal of neuroscience methods. vol 137. issue 1. 2004-09-16. PMID:15196826. |
the nucleus accumbens (nac) is an important component of circuitry that underlies reward related behaviors and the rewarding properties of drugs of abuse. |
2004-09-16 |
2023-08-12 |
mouse |
| C Giertler, I Bohn, W Haube. Transient inactivation of the rat nucleus accumbens does not impair guidance of instrumental behaviour by stimuli predicting reward magnitude. Behavioural pharmacology. vol 15. issue 1. 2004-08-02. PMID:15075627. |
the involvement of the nucleus accumbens (nac) in the determination of reaction times (rts) of instrumental responses by the expectancy of future reward was investigated. |
2004-08-02 |
2023-08-12 |
rat |
| C Giertler, I Bohn, W Haube. Transient inactivation of the rat nucleus accumbens does not impair guidance of instrumental behaviour by stimuli predicting reward magnitude. Behavioural pharmacology. vol 15. issue 1. 2004-08-02. PMID:15075627. |
inactivation of the nac by lidocaine had no effect on rts and their determination by cue-associated reward magnitudes, and did not affect the rate of correct responses. |
2004-08-02 |
2023-08-12 |
rat |
| Irene A Yun, Ken T Wakabayashi, Howard L Fields, Saleem M Nicol. The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 12. 2004-06-10. PMID:15044531. |
rats trained to perform an operant response to a cue to obtain a sucrose reward were implanted with both multiunit recording electrodes in the nac and microinjection cannulas in the vta. |
2004-06-10 |
2023-08-12 |
rat |
| Irene A Yun, Ken T Wakabayashi, Howard L Fields, Saleem M Nicol. The ventral tegmental area is required for the behavioral and nucleus accumbens neuronal firing responses to incentive cues. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 12. 2004-06-10. PMID:15044531. |
like vta baclofen injection, injection of dopamine receptor antagonists into the nac profoundly reduced cue-elicited reward seeking. |
2004-06-10 |
2023-08-12 |
rat |
| Saleem M Nicola, Irene A Yun, Ken T Wakabayashi, Howard L Field. Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues. Journal of neurophysiology. vol 91. issue 4. 2004-05-17. PMID:14645378. |
to examine how nac neurons encode information during reward consumption, we recorded the firing activity of rat nac neurons during the performance of a discriminative stimulus task. |
2004-05-17 |
2023-08-12 |
rat |
| Saleem M Nicola, Irene A Yun, Ken T Wakabayashi, Howard L Field. Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues. Journal of neurophysiology. vol 91. issue 4. 2004-05-17. PMID:14645378. |
another population of nac neurons was excited on exit from the reward receptacle. |
2004-05-17 |
2023-08-12 |
rat |
| Saleem M Nicola, Irene A Yun, Ken T Wakabayashi, Howard L Field. Firing of nucleus accumbens neurons during the consummatory phase of a discriminative stimulus task depends on previous reward predictive cues. Journal of neurophysiology. vol 91. issue 4. 2004-05-17. PMID:14645378. |
these findings are consistent with a contribution of nac neurons to both reward consummatory and reward seeking behavior. |
2004-05-17 |
2023-08-12 |
rat |
| Eliyahu Dremencov, Iris Gispan-Herman, Merav Rosenstein, Avivit Mendelman, David H Overstreet, Joseph Zohar, Gal Yadi. The serotonin-dopamine interaction is critical for fast-onset action of antidepressant treatment: in vivo studies in an animal model of depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 1. 2004-02-18. PMID:14687868. |
because of the central role of accumbal dopamine in the mediation of motivation and reward, our measurements were focused on dopaminergic neurotransmission in the nucleus accumbens (nac). |
2004-02-18 |
2023-08-12 |
rat |
| Michael H Joseph, Krishna Datla, Andrew M J Youn. The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition? Neuroscience and biobehavioral reviews. vol 27. issue 6. 2003-12-18. PMID:14599434. |
psychopharmacological studies have implicated the dopaminergic innervation of the nucleus accumbens (nac) in reward and reinforcement, in the actions of addictive drugs, and in the control of the symptoms of schizophrenia. |
2003-12-18 |
2023-08-12 |
rat |
| Michael H Joseph, Krishna Datla, Andrew M J Youn. The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition? Neuroscience and biobehavioral reviews. vol 27. issue 6. 2003-12-18. PMID:14599434. |
these results contrast with electrophysiological data obtained in the behaving monkey, where rewarding stimuli, or stimuli predictive of reward are associated with increased firing of presumptive dopamine neurones projecting to the nac (and indeed to the striatum), but mild aversive stimuli are not, leading to the suggestion that this system subserves a more purely reward function, or indeed that it provides a reward error signal. |
2003-12-18 |
2023-08-12 |
rat |
| Carrie L Walters, Yuo-Chen Kuo, Julie A Blend. Differential distribution of CREB in the mesolimbic dopamine reward pathway. Journal of neurochemistry. vol 87. issue 5. 2003-12-18. PMID:14622103. |
to investigate the complex nature of creb function in addiction, we examined the distribution of creb protein in the nucleus accumbens (nac) and ventral tegmental area (vta), two brain regions that are part of the well-defined mesolimbic dopamine pathway involved in reward processing. |
2003-12-18 |
2023-08-12 |
mouse |
| Susan R Sesack, David B Car. Selective prefrontal cortex inputs to dopamine cells: implications for schizophrenia. Physiology & behavior. vol 77. issue 4-5. 2003-07-11. PMID:12526992. |
dopamine (da) neurons in the substantia nigra (sn) and ventral tegmental area (vta) form several projection systems with diverse functions, such as motor planning through the striatum, reward seeking via the nucleus accumbens (nac), and cognitive control through the prefrontal cortex (pfc). |
2003-07-11 |
2023-08-12 |
Not clear |
| Jong Y Bahk, Shupeng Li, Moon S Park, Myeong O Ki. Dopamine D1 and D2 receptor mRNA up-regulation in the caudate-putamen and nucleus accumbens of rat brains by smoking. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452531. |
the neurotransmitter dopamine (da) is important in the reward and reinforcing properties of many addictive drugs: however, the effect of nicotine by cigarette smoking itself on the expression of da receptors in the caudate-putamen (cpu), nucleus accumbens (nac) and olfactory tubercle (otu) has not been elucidated completely. |
2003-03-26 |
2023-08-12 |
rat |
| K P Datla, R G Ahier, A M J Young, J A Gray, M H Josep. Conditioned appetitive stimulus increases extracellular dopamine in the nucleus accumbens of the rat. The European journal of neuroscience. vol 16. issue 10. 2003-03-05. PMID:12453062. |
this study used in vivo microdialysis to examine the release of dopamine (da) in the nucleus accumbens (nac) during the performance of a previously learned, signalled sucrose reward task, and during conditioning of a neutral tone stimulus to this reward. |
2003-03-05 |
2023-08-12 |
rat |
| Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, Gen Matsumoto, Taketoshi On. Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 13. 2002-07-19. PMID:12084937. |
the nucleus accumbens (nac) plays an important role in the integration of reward with motor function, and it receives dense dopamine innervation and extensive limbic and cortical afferents. |
2002-07-19 |
2023-08-12 |
mouse |
| David Robbe, Gerard Alonso, Severine Chaumont, Joel Bockaert, Olivier J Manzon. Role of p/q-Ca2+ channels in metabotropic glutamate receptor 2/3-dependent presynaptic long-term depression at nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 11. 2002-07-05. PMID:12040040. |
the nucleus accumbens (nac) is an important cerebral area involved in reward and spatial memory (pennartz et al., 1994), but little is known about synaptic plasticity in this region. |
2002-07-05 |
2023-08-12 |
Not clear |
| Steven R Laviolette, Karim Nader, Derek van der Koo. Motivational state determines the functional role of the mesolimbic dopamine system in the mediation of opiate reward processes. Behavioural brain research. vol 129. issue 1-2. 2002-04-11. PMID:11809491. |
in the present study, we report that bilateral microinjections of a da receptor antagonist, alpha-flupenthixol (0.3-3 microg/0.5 microl) into the nucleus accumbens (nac), blocks morphine reward (10 mg/kg, i.p.) |
2002-04-11 |
2023-08-12 |
Not clear |
| K Misra, A Roy, S C Pande. Effects of voluntary ethanol intake on the expression of Ca(2+) /calmodulin-dependent protein kinase IV and on CREB expression and phosphorylation in the rat nucleus accumbens. Neuroreport. vol 12. issue 18. 2002-03-18. PMID:11742252. |
this is the first evidence to suggest that decreased cam kinase iv-dependent creb phosphorylation in the shell region of nac may play a role in the reward mechanisms of alcohol drinking. |
2002-03-18 |
2023-08-12 |
rat |
| Magdalena Mas Nieto, Jodie Wilson, Annie Cupo, Bernard P Roques, Florence Nobl. Chronic morphine treatment modulates the extracellular levels of endogenous enkephalins in rat brain structures involved in opiate dependence: a microdialysis study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 3. 2002-02-27. PMID:11826132. |
these changes in opioid peptides in the nac may reflect an "emotional state" of the animals in relation to the expectation of drug reward (reinforcing effects of morphine). |
2002-02-27 |
2023-08-12 |
rat |