| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Arjunan Sundaresan, Ranganathan Harini, Kodukkur Viswanathan Pugalend. Ursolic acid and rosiglitazone combination alleviates metabolic syndrome in high fat diet fed C57BL/6J mice. General physiology and biophysics. vol 31. issue 3. 2013-01-03. PMID:23047945. |
upon feeding high fat diet (hfd) c57bl/6j mice developed obesity, insulin resistance, dyslipidemia and hypertension. |
2013-01-03 |
2023-08-12 |
mouse |
| Pyung-Hwan Kim, Minhyung Lee, Sung Wan Ki. Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model. Journal of controlled release : official journal of the Controlled Release Society. vol 162. issue 1. 2013-01-02. PMID:22705459. |
exendin-4, glucagon-like peptide 1 (glp-1) receptor agonist, is an exocrine hormone, which has potent insulinotropic actions similar to glp-1 such as stimulating insulin biosynthesis, facilitating glucose concentration dependent insulin secretion, slowing gastric emptying, reducing food intake and stimulating β-cell proliferation. |
2013-01-02 |
2023-08-12 |
mouse |
| Tingqing Guo, Nichole D Bond, William Jou, Oksana Gavrilova, Jennifer Portas, Alexandra C McPherro. Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy. Diabetes. vol 61. issue 10. 2012-12-28. PMID:22596054. |
lipodystrophies are characterized by a loss of white adipose tissue, which causes ectopic lipid deposition, peripheral insulin resistance, reduced adipokine levels, and increased food intake (hyperphagia). |
2012-12-28 |
2023-08-12 |
mouse |
| Gale B Carey, Lisa C Merril. Meal-feeding rodents and toxicology research. Chemical research in toxicology. vol 25. issue 8. 2012-12-26. PMID:22642213. |
rhythms of plasma insulin and glucagon that fluctuate with food ingestion are also altered by feeding schedule; ad libitum feeding promotes hyperinsulinemia which is a precursor for developing diabetes. |
2012-12-26 |
2023-08-12 |
Not clear |
| T E Adrian, S Gariballa, K A Parekh, S A Thomas, H Saadi, J Al Kaabi, N Nagelkerke, B Gedulin, A A Youn. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. vol 55. issue 9. 2012-12-18. PMID:22696033. |
rectal taurocholate increases l cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. |
2012-12-18 |
2023-08-12 |
human |
| T E Adrian, S Gariballa, K A Parekh, S A Thomas, H Saadi, J Al Kaabi, N Nagelkerke, B Gedulin, A A Youn. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. vol 55. issue 9. 2012-12-18. PMID:22696033. |
we investigated the effects of intrarectal sodium taurocholate on plasma glp-1, pyy, insulin and glucose concentrations, and on food intake of a subsequent meal. |
2012-12-18 |
2023-08-12 |
human |
| Seung-Hyun Hong, Kyu-Sun Lee, Su-Jin Kwak, Ae-Kyeong Kim, Hua Bai, Min-Su Jung, O-Yu Kwon, Woo-Joo Song, Marc Tatar, Kweon Y. Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals. PLoS genetics. vol 8. issue 8. 2012-12-17. PMID:22876196. |
conversely, akt-mediated insulin signaling suppressed foxo-mediated snpf/npy expression, which resulted in decreasing food intake. |
2012-12-17 |
2023-08-12 |
mouse |
| Brian D Nielsen, Mandi M Vick, Patricia M Denni. A potential link between insulin resistance and iron overload disorder in browsing rhinoceroses investigated through the use of an equine model. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. vol 43. issue 3 Suppl. 2012-12-17. PMID:23156707. |
the strongest correlation was between ferritin and insulin auc after dextrose administration (r = 0.61; p = 0.01) followed by auc after feeding a meal of pelleted corn (r = 0.60; p = 0.01), with the correlation for peak insulin being 0.53 (p = 0.03) after dextrose administration and 0.56 (p = 0.02) after pelleted corn. |
2012-12-17 |
2023-08-12 |
Not clear |
| Karine Badonnel, Marie-Christine Lacroix, Régine Monnerie, Didier Durieux, Monique Caillol, Christine Bal. Chronic restricted access to food leading to undernutrition affects rat neuroendocrine status and olfactory-driven behaviors. Hormones and behavior. vol 62. issue 2. 2012-12-13. PMID:22633909. |
here, we addressed the issue of a long-term modulation of their neuroendocrine status by evaluating the effect of chronic food restriction in rats following a limitation of the duration of daily food intake to 2 h (sf) instead of 8 h (lf) on the expression of insulin and leptin system in the olfactory mucosa and bulb and on olfactory behaviors. |
2012-12-13 |
2023-08-12 |
rat |
| Karine Badonnel, Marie-Christine Lacroix, Régine Monnerie, Didier Durieux, Monique Caillol, Christine Bal. Chronic restricted access to food leading to undernutrition affects rat neuroendocrine status and olfactory-driven behaviors. Hormones and behavior. vol 62. issue 2. 2012-12-13. PMID:22633909. |
this restriction resulted in a one-third reduction in the daily food intake and a 25% reduction in the body weight of sf rats when compared to controls, and was accompanied by lower levels of triglycerides, glucose, insulin and leptin in sf rats. |
2012-12-13 |
2023-08-12 |
rat |
| Yan-Chuan Shi, Constanze Maria Hämmerle, I-Chieh Jennifer Lee, Nigel Turner, Amy D Nguyen, Sabrina J Riepler, Shu Lin, Amanda Sainsbury, Herbert Herzog, Lei Zhan. Adult-onset PYY overexpression in mice reduces food intake and increases lipogenic capacity. Neuropeptides. vol 46. issue 4. 2012-12-11. PMID:22575886. |
taken together, these findings demonstrate that under physiological conditions, pyy reduces food intake while enhancing lipogenic capacity and insulin action, likely contributing to fuel assimilation in the postprandial state. |
2012-12-11 |
2023-08-12 |
mouse |
| Pankaj K Bagul, Harish Middela, Saidulu Matapally, Raju Padiya, Tanmay Bastia, K Madhusudana, B Raghunath Reddy, Sumana Chakravarty, Sanjay K Banerje. Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. Pharmacological research. vol 66. issue 3. 2012-12-11. PMID:22627169. |
at the end of the feeding schedule, dia group had insulin resistance along with increased blood glucose, triglyceride, uric acid and nitric oxide (no) levels. |
2012-12-11 |
2023-08-12 |
rat |
| Xiaoke Wang, Aiguo Ge, Mengjie Cheng, Fangfang Guo, Min Zhao, Xiaoqi Zhou, Liegang Liu, Nianhong Yan. Increased hypothalamic inflammation associated with the susceptibility to obesity in rats exposed to high-fat diet. Experimental diabetes research. vol 2012. 2012-12-11. PMID:22844271. |
inflammation has been implicated in the hypothalamic leptin and insulin resistance resulting defective food intake during high fat diet period. |
2012-12-11 |
2023-08-12 |
rat |
| Barbara C Fam, Laura J Rose, Rebecca Sgambellone, Zheng Ruan, Joseph Proietto, Sofianos Andrikopoulo. Normal muscle glucose uptake in mice deficient in muscle GLUT4. The Journal of endocrinology. vol 214. issue 3. 2012-12-10. PMID:22736482. |
high-fat feeding did not alter glucose tolerance in the ko mice but led to elevated plasma insulin levels during the glucose tolerance test. |
2012-12-10 |
2023-08-12 |
mouse |
| Thomas Scherer, Claudia Lindtner, Elizabeth Zielinski, James O'Hare, Nika Filatova, Christoph Buettne. Short term voluntary overfeeding disrupts brain insulin control of adipose tissue lipolysis. The Journal of biological chemistry. vol 287. issue 39. 2012-12-07. PMID:22810223. |
short term hfd feeding led to a 37% increase in caloric intake and elevated base-line free fas and insulin levels compared with rats fed regular chow. |
2012-12-07 |
2023-08-12 |
human |
| Jeffrey S Dubins, Manuel Sanchez-Alavez, Victor Zhukov, Alejandro Sanchez-Gonzalez, Gianluca Moroncini, Santos Carvajal-Gonzalez, John R Hadcock, Tamas Bartfai, Bruno Cont. Downregulation of GPR83 in the hypothalamic preoptic area reduces core body temperature and elevates circulating levels of adiponectin. Metabolism: clinical and experimental. vol 61. issue 10. 2012-12-03. PMID:22560055. |
mice received poa injection of shgpr83 or non-silencing vectors and were monitored for cbt, motor activity, food intake body weight and circulating levels of igf-1, insulin, leptin and adiponectin. |
2012-12-03 |
2023-08-12 |
mouse |
| Dmitry M Mebel, Jovi C Y Wong, Yifei J Dong, Stephanie L Borglan. Insulin in the ventral tegmental area reduces hedonic feeding and suppresses dopamine concentration via increased reuptake. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22712725. |
insulin receptors are expressed on dopaminergic neurons of the ventral tegmental area (vta), and insulin may act in the vta to suppress feeding. |
2012-11-30 |
2023-08-12 |
mouse |
| Dmitry M Mebel, Jovi C Y Wong, Yifei J Dong, Stephanie L Borglan. Insulin in the ventral tegmental area reduces hedonic feeding and suppresses dopamine concentration via increased reuptake. The European journal of neuroscience. vol 36. issue 3. 2012-11-30. PMID:22712725. |
finally, insulin administered to the vta depressed sated feeding of sweetened high-fat food. |
2012-11-30 |
2023-08-12 |
mouse |
| Li Hou, Mei-Juan Cai, Wen Liu, Qian Song, Xiao-Fan Zha. Small GTPase Rab4b participates in the gene transcription of 20-hydroxyecdysone and insulin pathways to regulate glycogen level and metamorphosis. Developmental biology. vol 371. issue 1. 2012-11-30. PMID:22824427. |
the transcription of rab4b could be upregulated by insulin injection or glucose feeding to the larvae, but not by 20e or juvenile hormone analogy methoprene. |
2012-11-30 |
2023-08-12 |
Not clear |
| Nina Herzog, Alexia Friedrich, Naoko Fujita, Steffen Gais, Kamila Jauch-Chara, Kerstin M Oltmanns, Christian Benedic. Effects of daytime food intake on memory consolidation during sleep or sleep deprivation. PloS one. vol 7. issue 6. 2012-11-27. PMID:22768272. |
bearing in mind that food intake produces many metabolic signals that can influence memory processing in humans (e.g., insulin), the present study addressed the question as to whether the enhancing effect of sleep on memory consolidation is affected by the amount of energy consumed during the preceding daytime. |
2012-11-27 |
2023-08-12 |
human |