| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian J DeBosch, Maggie Chi, Kelle H Mole. Glucose transporter 8 (GLUT8) regulates enterocyte fructose transport and global mammalian fructose utilization. Endocrinology. vol 153. issue 9. 2012-10-29. PMID:22822162. |
strikingly, long-term hfrd feeding in glut8ko mice exacerbated fructose-induced increases in blood pressure, serum insulin, low-density lipoprotein and total cholesterol vs. wild-type controls. |
2012-10-29 |
2023-08-12 |
mouse |
| Jayanthi Maniam, Margaret J Morri. The link between stress and feeding behaviour. Neuropharmacology. vol 63. issue 1. 2012-10-23. PMID:22710442. |
stress-induced bidirectional feeding responses underline the complex mechanisms and multiple contributing factors, including the levels of glucocorticoids (dependent on the severity of a stressor), the interaction between glucocorticoids and feeding related neuropeptides such as neuropeptide y (npy), alpha-melanocyte stimulating hormone (α-msh), agouti-related protein (agrp), melanocortins and their receptors, crh, urocortin and peripheral signals (leptin, insulin and ghrelin). |
2012-10-23 |
2023-08-12 |
Not clear |
| L Torres-Rovira, S Astiz, A Caro, C Lopez-Bote, C Ovilo, P Pallares, M L Perez-Solana, R Sanchez-Sanchez, A Gonzalez-Bulne. Diet-induced swine model with obesity/leptin resistance for the study of metabolic syndrome and type 2 diabetes. TheScientificWorldJournal. vol 2012. 2012-10-19. PMID:22629144. |
after three months of differential feeding, sfad animals developed central obesity, dyslipidemia, insulin resistance and impaired glucose tolerance, and elevated blood pressure; the five parameters associated with the metabolic syndrome. |
2012-10-19 |
2023-08-12 |
Not clear |
| Akira Kitagawa, Yoshiji Ohta, Koji Ohash. Melatonin improves metabolic syndrome induced by high fructose intake in rats. Journal of pineal research. vol 52. issue 4. 2012-10-17. PMID:22220562. |
feeding of a diet containing 60% fructose (hfd) for 4 or 6 wk caused increased serum insulin, triglyceride, total cholesterol, free fatty acids, uric acid, leptin, and lipid peroxide concentrations as well as hepatic triglyceride and cholesterol concentrations, and relative intra-abdominal fat and liver weights. |
2012-10-17 |
2023-08-12 |
rat |
| Akira Kitagawa, Yoshiji Ohta, Koji Ohash. Melatonin improves metabolic syndrome induced by high fructose intake in rats. Journal of pineal research. vol 52. issue 4. 2012-10-17. PMID:22220562. |
in an oral glucose tolerance test, rats with 4- or 6-wk hfd feeding showed higher serum insulin response curve and normal serum glucose response curve when compared with the corresponding animals that received the control diet. |
2012-10-17 |
2023-08-12 |
rat |
| Akira Kitagawa, Yoshiji Ohta, Koji Ohash. Melatonin improves metabolic syndrome induced by high fructose intake in rats. Journal of pineal research. vol 52. issue 4. 2012-10-17. PMID:22220562. |
the 4- or 6-wk hfd feeding caused insulin resistance, judging from the scores of homr-ir and quicki, which are indices of insulin resistance. |
2012-10-17 |
2023-08-12 |
rat |
| Akira Kitagawa, Yoshiji Ohta, Koji Ohash. Melatonin improves metabolic syndrome induced by high fructose intake in rats. Journal of pineal research. vol 52. issue 4. 2012-10-17. PMID:22220562. |
the daily administered melatonin (1 or 10mg/kg body weight) ameliorated the higher serum insulin response curve in the oral glucose tolerance test and insulin resistance at 6-wk hfd feeding more effectively at its higher dose than at its lower dose. |
2012-10-17 |
2023-08-12 |
rat |
| K Ganesh Kumar, Jingying Zhang, Su Gao, Jari Rossi, Owen P McGuinness, Heather H Halem, Michael D Culler, Randall L Mynatt, Andrew A Butle. Adropin deficiency is associated with increased adiposity and insulin resistance. Obesity (Silver Spring, Md.). vol 20. issue 7. 2012-10-17. PMID:22318315. |
adropin is not required for regulating food intake, however, its functions impact on adiposity and are involved in preventing insulin resistance, dyslipidemia, and impaired glucose tolerance. |
2012-10-17 |
2023-08-12 |
mouse |
| Chih-Yen Chen, Chang-Youh Tsai, Wei-Jei Lee, Wen-Jinn Liaw, Chi-Huei Chiang, Shung-Tai Ho, Shou-Dong Le. Intracerebroventricular O-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or CRF receptor, in satiated rats. Nutrition (Burbank, Los Angeles County, Calif.). vol 28. issue 7-8. 2012-10-16. PMID:22465905. |
intracerebroventricular o-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or crf receptor, in satiated rats. |
2012-10-16 |
2023-08-12 |
rat |
| Chih-Yen Chen, Chang-Youh Tsai, Wei-Jei Lee, Wen-Jinn Liaw, Chi-Huei Chiang, Shung-Tai Ho, Shou-Dong Le. Intracerebroventricular O-n-octanoylated ghrelin and its splice variant-induced feeding is blocked by insulin, independent of obestatin or CRF receptor, in satiated rats. Nutrition (Burbank, Los Angeles County, Calif.). vol 28. issue 7-8. 2012-10-16. PMID:22465905. |
the purpose of this study was to investigate the impact of intracerebroventricular (icv) injection of the two endogenous forms of acyl ghrelin, o-n-octanoylated ghrelin and des-gln¹⁴-ghrelin, on feeding behavior, as well as their interactions with insulin, obestatin, and corticotropin-releasing factor receptor (crf-r) antagonist in the forebrain to influence food intake. |
2012-10-16 |
2023-08-12 |
rat |
| Jennifer L Adolphe, Murray D Drew, Qian Huang, Tawni I Silver, Lynn P Webe. Postprandial impairment of flow-mediated dilation and elevated methylglyoxal after simple but not complex carbohydrate consumption in dogs. Nutrition research (New York, N.Y.). vol 32. issue 4. 2012-10-11. PMID:22575041. |
blood samples were taken prefeeding and at timed intervals after feeding to measure serum glucose, insulin, nitrotyrosine, and methylglyoxal. |
2012-10-11 |
2023-08-12 |
Not clear |
| Elaine Xu, Alexandre Charbonneau, Yannève Rolland, Kerstin Bellmann, Lily Pao, Katherine A Siminovitch, Benjamin G Neel, Nicole Beauchemin, André Marett. Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance. Diabetes. vol 61. issue 8. 2012-10-08. PMID:22698917. |
to investigate the role of shp1 in hepatic insulin resistance, we generated hepatocyte-specific shp1 knockout mice (ptpn6(h-ko)), which were subjected to extensive metabolic monitoring throughout an 8-week standard chow diet (sd) or high-fat diet (hfd) feeding. |
2012-10-08 |
2023-08-12 |
mouse |
| Elaine Xu, Alexandre Charbonneau, Yannève Rolland, Kerstin Bellmann, Lily Pao, Katherine A Siminovitch, Benjamin G Neel, Nicole Beauchemin, André Marett. Hepatocyte-specific Ptpn6 deletion protects from obesity-linked hepatic insulin resistance. Diabetes. vol 61. issue 8. 2012-10-08. PMID:22698917. |
after hfd feeding, ptpn6(h-ko) mice developed comparable levels of obesity as ptpn6(f/f) mice, but they were remarkably protected from liver insulin resistance, as revealed by euglycemic clamps and hepatic insulin signaling determinations. |
2012-10-08 |
2023-08-12 |
mouse |
| K F Elliott, J S Rand, L M Fleeman, J M Morton, A L Litster, V C Biourge, P J Markwel. A diet lower in digestible carbohydrate results in lower postprandial glucose concentrations compared with a traditional canine diabetes diet and an adult maintenance diet in healthy dogs. Research in veterinary science. vol 93. issue 1. 2012-10-03. PMID:21944832. |
postprandial glucose, insulin, and triglyceride concentrations in some dogs did not return to baseline by 12 h after feeding of each of the three diets. |
2012-10-03 |
2023-08-12 |
dog |
| Christopher B Newgar. Interplay between lipids and branched-chain amino acids in development of insulin resistance. Cell metabolism. vol 15. issue 5. 2012-10-03. PMID:22560213. |
nevertheless, in animal feeding studies, bcaa supplementation requires the background of a high-fat diet to promote insulin resistance. |
2012-10-03 |
2023-08-12 |
Not clear |
| Jessica T Y Yue, Tony K T La. Lipid sensing and insulin resistance in the brain. Cell metabolism. vol 15. issue 5. 2012-10-03. PMID:22560217. |
lipid sensing and insulin signaling in the brain independently triggers a negative feedback system to lower glucose production and food intake. |
2012-10-03 |
2023-08-12 |
Not clear |
| Jessica T Y Yue, Tony K T La. Lipid sensing and insulin resistance in the brain. Cell metabolism. vol 15. issue 5. 2012-10-03. PMID:22560217. |
here, we discuss the underlying molecular and neuronal mechanisms of lipid sensing and insulin signaling in the hypothalamus and how these mechanisms are affected in response to high-fat feeding. |
2012-10-03 |
2023-08-12 |
Not clear |
| Jessica T Y Yue, Tony K T La. Lipid sensing and insulin resistance in the brain. Cell metabolism. vol 15. issue 5. 2012-10-03. PMID:22560217. |
we propose that high-fat feeding concurrently disrupts hypothalamic insulin-signaling and lipid-sensing mechanisms and that experiments aimed to restore both insulin action and lipid sensing in the brain could effectively lower glucose production and food intake to restore metabolic homeostasis in type 2 diabetes and obesity. |
2012-10-03 |
2023-08-12 |
Not clear |
| S Mougiakakou, K Prountzou, K Nikit. A real time simulation model of glucose-insulin metabolism for type 1 diabetes patients. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference. vol 2006. 2012-10-02. PMID:17282172. |
the data contain information about measured blood glucose levels, insulin intake, and description of food intake, along with the corresponding time. |
2012-10-02 |
2023-08-12 |
Not clear |
| M J McKinley, B J Oldfiel. The brain as an endocrine target for Peptide hormones. Trends in endocrinology and metabolism: TEM. vol 9. issue 9. 2012-10-02. PMID:18406304. |
there are some circulating peptides such as insulin and leptin that are transported from the bloodstream across cerebral blood vessel walls into sites in the hypothalamus that have appropriate neural connections to influence food intake and sympathetic control of brown fat. |
2012-10-02 |
2023-08-12 |
Not clear |