| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Le Kang, Yan-Xue Li, Du-Juan Dong, Jin-Xing Wang, Xiao-Fan Zha. 20-Hydroxyecdysone counteracts insulin to promote programmed cell death by modifying phosphoglycerate kinase 1. BMC biology. vol 21. issue 1. 2023-05-24. PMID:37226192. |
insulin regulates glycolysis during the larval feeding stage, allowing the insects to grow and live. |
2023-05-24 |
2023-08-14 |
Not clear |
| Xiaoxi Xu, Anoop Arunagiri, Maroof Alam, Leena Haataja, Charles R Evans, Ivy Zhao, Roberto Castro-Gutierrez, Holger A Russ, Caroline Demangel, Ling Qi, Billy Tsai, Ming Liu, Peter Arva. Nutrient-dependent regulation of β-cell proinsulin content. The Journal of biological chemistry. 2023-05-20. PMID:37209827. |
we show that nutrient feeding is primarily linked to rapid de-phosphorylation of translation initiation factor eif2α, presaging increased proinsulin levels (and thereafter, insulin levels), followed by its re-phosphorylation during the ensuing hours that correspond to a fall in proinsulin levels. |
2023-05-20 |
2023-08-14 |
human |
| Ria Schönauer, Wenjun Jin, Christin Findeisen, Irene Valenzuela, Laura Alice Devlin, Jill Murrell, Emma C Bedoukian, Linda Pöschla, Elena Hantmann, Korbinian M Riedhammer, Julia Hoefele, Konrad Platzer, Ronald Biemann, Philipp M Campeau, Johannes Münch, Henrike Heyne, Anne Hoffmann, Adhideb Ghosh, Wenfei Sun, Hua Dong, Falko Noé, Christian Wolfrum, Emily Woods, Michael J Parker, Ruxandra Neatu, Gwenael Le Guyader, Ange-Line Bruel, Laurence Perrin, Helena Spiewak, Isabelle Missotte, Melanie Fourgeaud, Vincent Michaud, Didier Lacombe, Sarah A Paolucci, Jillian G Buchan, Margaret Glissmeyer, Bernt Popp, Matthias Blüher, John A Sayer, Jan Halbritte. Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions. American journal of human genetics. 2023-05-19. PMID:37207645. |
affected individuals presented with low-to-normal birth weight and infantile feeding difficulties but developed insulin resistance and hyperphagia during childhood. |
2023-05-19 |
2023-08-14 |
Not clear |
| Abhiram Charan Tej Mallu, Sivapriya Sivagurunathan, Debasish Paul, Hobby Aggarwal, Abel Arul Nathan, Amrutha Manikandan, Mahalakshmi M Ravi, Ramanamurthy Boppana, Kumaravelu Jagavelu, Manas Kumar Santra, Madhulika Dixi. Feeding enhances fibronectin adherence of quiescent lymphocytes through non-canonical insulin signalling. Immunology. 2023-05-15. PMID:37185810. |
feeding enhances fibronectin adherence of quiescent lymphocytes through non-canonical insulin signalling. |
2023-05-15 |
2023-08-14 |
mouse |
| Abhiram Charan Tej Mallu, Sivapriya Sivagurunathan, Debasish Paul, Hobby Aggarwal, Abel Arul Nathan, Amrutha Manikandan, Mahalakshmi M Ravi, Ramanamurthy Boppana, Kumaravelu Jagavelu, Manas Kumar Santra, Madhulika Dixi. Feeding enhances fibronectin adherence of quiescent lymphocytes through non-canonical insulin signalling. Immunology. 2023-05-15. PMID:37185810. |
despite being exposed to periodic alterations in blood insulin levels upon fasting and feeding, studies exploring the physiological effects of these hormonal changes on quiescent immune cell function and trafficking are scanty. |
2023-05-15 |
2023-08-14 |
mouse |
| Rufeng Xu, Kaiyuan Wang, Zhengjian Yao, Yan Zhang, Li Jin, Jing Pang, Yuncai Zhou, Kai Wang, Dechen Liu, Yaqin Zhang, Peng Sun, Fuqiang Wang, Xiaoai Chang, Tengli Liu, Shusen Wang, Yalin Zhang, Shuyong Lin, Cheng Hu, Yunxia Zhu, Xiao Ha. BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes. Journal of molecular cell biology. 2023-05-15. PMID:37188647. |
the enhanced basal insulin secretion drives insulin resistance and β-cell exhaustion, and thus the onset of t2dm in mice with hfd feeding or β-cell gain-of-function brsk2. |
2023-05-15 |
2023-08-14 |
mouse |
| J M Huzzey, J P Jarrett, E D Sharman, M Garcia, J D Chapman, D J McLea. Effects of OmniGen AF feed supplementation on glucocorticoids, blood leukocyte messenger RNA abundance, and energy metabolism in overstocked Holstein dairy cows. Animal : an international journal of animal bioscience. vol 17. issue 5. 2023-05-07. PMID:37149993. |
feeding og during overstocking delayed the increase in fecal cortisol metabolites by several days; however, it is unclear if this altered glucocorticoid response benefited the cow, as og had no effect on insulin responses or immune parameters. |
2023-05-07 |
2023-08-14 |
cattle |
| Zhenzhen Qi, Xiaosheng Tao, Guohongfang Tan, Bin Tian, Lehao Zhang, Subhas C Kundu, Shenzhou L. Electro-responsive silk fibroin microneedles for controlled release of insulin. International journal of biological macromolecules. 2023-05-06. PMID:37148951. |
in vivo studies on type 1 diabetic mice show that electro-responsive insulin delivery system effectively controls the blood glucose before and after feeding by switching on and off the power supply, and this blood glucose control can be maintained within the safe range (100-200 mg/dl) for a long time (11h). |
2023-05-06 |
2023-08-14 |
mouse |
| María E Casado, Sandra Canelles, Eduardo Arilla-Ferreiro, Laura M Frago, Vicente Barrio. Changes in Lipid Metabolism Enzymes in Rat Epididymal Fat after Chronic Central Leptin Infusion Are Related to Alterations in Inflammation and Insulin Signaling. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108229. |
leptin inhibits food intake and reduces the size of body fat depots, changing adipocyte sensitivity to insulin to restrain lipid accrual. |
2023-04-28 |
2023-08-14 |
rat |
| Eva Gonzalez-Flo, Elaheh Kheirabadi, Carlos Rodriguez-Caso, Javier Mací. Evolutionary algorithm for the optimization of meal intake and insulin administration in patients with type 2 diabetes. Frontiers in physiology. vol 14. 2023-04-24. PMID:37089422. |
we found that an appropriate distribution of food intake throughout the day permits a reduction in the insulin dose required to maintain glycemia within the range recommended by the american diabetes association for patients with t2dm of a range of severities. |
2023-04-24 |
2023-08-14 |
Not clear |
| Ajit Singh Mahla, Suresh Kumar Bunkar, Babu Lal Kumawat, Vijay Kumar Saxena, Sellappan Selvaraju, Randhir Singh Bhatt, Raghvendar Singh, Arun Kuma. Dietary n-3 PUFA augments pre-ovulatory follicle turnover and prolificacy in well-fed ewes. Animal reproduction science. vol 252. 2023-04-22. PMID:37086576. |
plasma cholesterol, estradiol, and insulin concentrations were lower (p < 0.01) in ewes fed with fo than those offered po group at the end of the feeding period. |
2023-04-22 |
2023-08-14 |
Not clear |
| Laura Aponte Becerra, Anna Gavrieli, Faizan Khan, Peter Novak, Vasileios Lioutas, Long H Ngo, Vera Novak, Christos S Mantzoro. Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. Clinical nutrition (Edinburgh, Scotland). vol 42. issue 6. 2023-04-21. PMID:37084469. |
daily intranasal insulin at 40iu does not affect food intake and body composition: a placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. |
2023-04-21 |
2023-08-14 |
human |
| Laura Aponte Becerra, Anna Gavrieli, Faizan Khan, Peter Novak, Vasileios Lioutas, Long H Ngo, Vera Novak, Christos S Mantzoro. Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. Clinical nutrition (Edinburgh, Scotland). vol 42. issue 6. 2023-04-21. PMID:37084469. |
centrally administered insulin stimulates the reward system to reduce appetite in response to food intake in animal studies. |
2023-04-21 |
2023-08-14 |
human |
| Rajendran Harishkumar, Eva M Baranda-Alonso, William P Martin, Neil G Dochert. Impact of time-restricted feeding on kidney injury in male rats with experimental metabolic syndrome. Experimental physiology. 2023-04-19. PMID:37074338. |
changes in food intake, body weight, blood pressure, glucose tolerance, fasting plasma insulin, urinary excretion of c-peptide and renal injury biomarkers, liver and kidney histopathology and inflammation, and fibrosis-related renal gene expression will be assessed as secondary outcomes. |
2023-04-19 |
2023-08-14 |
rat |
| Jia Liu, Kevin W Aylor, Zhenqi Li. Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-induced Obesity. Diabetes. 2023-04-19. PMID:37074396. |
to examine whether exercise and glucagon-like peptide 1 (glp-1) receptor agonism, alone or in combination, modulate vascular and metabolic insulin actions during obesity development, we performed a euglycemic insulin clamp in adult male rats after 2 weeks of high-fat diet feeding with either access to running wheel (exercise), liraglutide, or both. |
2023-04-19 |
2023-08-14 |
rat |
| Takuma Yasuda, Norio Harada, Tomonobu Hatoko, Atsuhiko Ichimura, Eri Ikeguchi-Ogura, Yuki Murata, Naoki Wada, Sakura Kiyobayashi, Shunsuke Yamane, Akira Hirasawa, Nobuya Inagak. Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding. American journal of physiology. Endocrinology and metabolism. 2023-04-19. PMID:37074989. |
inhibition of gpr120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding. |
2023-04-19 |
2023-08-14 |
Not clear |
| Inna I Zorina, Natalia F Avrova, Irina O Zakharova, Alexander O Shpako. Prospects for the Use of Intranasally Administered Insulin and Insulin-Like Growth Factor-1 in Cerebral Ischemia. Biochemistry. Biokhimiia. vol 88. issue 3. 2023-04-19. PMID:37076284. |
insulin and insulin-like growth factor-1 (igf-1) play a key role in the brain functioning by regulating the growth, differentiation, and survival of neurons, neuronal plasticity, food intake, peripheral metabolism, and endocrine functions. |
2023-04-19 |
2023-08-14 |
Not clear |
| Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, J Andrew Pospisili. A rapid microglial metabolic response controls metabolism and improves memory. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066282. |
chronic high-fat feeding triggers widespread metabolic dysfunction including obesity, insulin resistance, and diabetes. |
2023-04-17 |
2023-08-14 |
Not clear |
| Kristie I Aamodt, Alvin C Power. Peeling the onion: another layer in the regulation of insulin secretion. The Journal of clinical investigation. vol 133. issue 8. 2023-04-17. PMID:37066881. |
report that short-term dynamic changes in histone modifications regulated insulin secretion and acute β cell adaptations in response to fasting and feeding cycles. |
2023-04-17 |
2023-08-14 |
Not clear |
| Mutaz Amin, Rongling Wu, Claudia Gragnol. Novel Risk Variants in the Oxytocin Receptor Gene ( International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047255. |
recently, the oxytocin system was found to play other metabolic roles such as regulation of food intake, peripheral glucose uptake, and insulin sensitivity. |
2023-04-13 |
2023-08-14 |
Not clear |