| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amanda E Brandon, Lewin Small, Tuong-Vi Nguyen, Eurwin Suryana, Henry Gong, Christian Yassmin, Sarah E Hancock, Tamara Pulpitel, Sophie Stonehouse, Letisha Prescott, Melkam A Kebede, Belinda Yau, Lake-Ee Quek, Greg M Kowalski, Clinton R Bruce, Nigel Turner, Gregory J Coone. Insulin sensitivity is preserved in mice made obese by feeding a high starch diet. eLife. vol 11. 2022-11-17. PMID:36394259. |
insulin sensitivity is preserved in mice made obese by feeding a high starch diet. |
2022-11-17 |
2023-08-14 |
mouse |
| Candida J Rebello, Robbie A Beyl, Frank L Greenway, Kelly C Atteberry, Kristin K Hoddy, John P Kirwa. Low-Energy Dense Potato- and Bean-Based Diets Reduce Body Weight and Insulin Resistance: A Randomized, Feeding, Equivalence Trial. Journal of medicinal food. 2022-11-11. PMID:36367708. |
low-energy dense potato- and bean-based diets reduce body weight and insulin resistance: a randomized, feeding, equivalence trial. |
2022-11-11 |
2023-08-14 |
human |
| Nicolas Lanthier, Valérie Lebrun, Olivier Molendi-Coste, Nico van Rooijen, Isabelle A Leclerc. Liver Fetuin-A at Initiation of Insulin Resistance. Metabolites. vol 12. issue 11. 2022-11-10. PMID:36355106. |
in conclusion, this study demonstrated liver fetuin-a overexpression at the initiation of high-fat diet feeding, concurrent with hepatic steatosis and insulin resistance. |
2022-11-10 |
2023-08-14 |
mouse |
| Liang Xu, Haoran Li, Ouyang Zhang, Fengming Zhang, Menghui Song, Mengchen Ma, Youjuan Zhao, Rongxiu Ding, Dandan Li, Zhixiong Dong, Shengnan Jin, Weiping Han, Chunming Din. Melatonin alleviates diet-induced steatohepatitis by targeting multiple cell types in the liver to suppress inflammation and fibrosis. Journal of molecular endocrinology. 2022-11-10. PMID:36356262. |
in a mouse nash model with feeding of a methionine and choline-deficient (mcd) diet, mel administration suppressed lipid accumulation and peroxidation, improved insulin sensitivity, attenuated inflammation and fibrogenesis in the liver. |
2022-11-10 |
2023-08-14 |
mouse |
| Elise North, Imogene Thayer, Stuart Galloway, Mee Young Hong, Shirin Hooshmand, Changqi Liu, Lauren Okamoto, Timothy O'Neal, Jordan Philpott, Vernon Uganiza Rayo, Oliver C Witard, Mark Ker. Effects of short-term pistachio consumption before and throughout recovery from an intense exercise bout on cardiometabolic markers. Metabolism open. vol 16. 2022-11-07. PMID:36337429. |
plasma biomarkers (lipid profile, glucose, and insulin) were measured at the end of each 2-week feeding period immediately before the exercise bout and again 24, 48, and 72 h thereafter. |
2022-11-07 |
2023-08-14 |
human |
| Yoshimitsu Ouchi, Yoshinori Komaki, Kensuke Shimizu, Natsuki Fukano, Toshihisa Sugino, Jun-Ichi Shiraishi, Vishwajit S Chowdhury, Takashi Bung. Comparison of oral administration of fructose and glucose on food intake and physiological parameters in broiler chicks. Poultry science. vol 102. issue 1. 2022-11-06. PMID:36335736. |
after treatment, measurements of food intake (at 0, 30, and 60 min), and blood glucose as well as insulin concentrations were measured over time; however, diencephalic (hypothalamus) gene expression and plasma metabolites were measured at 30 min. |
2022-11-06 |
2023-08-14 |
Not clear |
| Hao Duan, Fei He, Weizhou Wang, Yanghao Wang, Chenli Yang, Yihan Lin, Ming Li, You L. Glucose-independent insulin and glucagon secreted from ventral pancreas sharing a similar pattern in healthy adult rat. Veterinary research forum : an international quarterly journal. vol 13. issue 3. 2022-11-02. PMID:36320302. |
elevated blood glucose concentration due to food intake will trigger insulin secretion from the dorsal pancreas has been extensively studied. |
2022-11-02 |
2023-08-14 |
rat |
| Anzela Niraula, Rachael D Fasnacht, Kelly M Ness, Jeremy M Frey, Sophia A Cuschieri, Mauricio D Dorfman, Joshua P Thale. Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity. Diabetes. 2022-11-01. PMID:36318114. |
these findings reveal that microglial ep4 signaling promotes body weight gain and insulin resistance during hfd feeding. |
2022-11-01 |
2023-08-14 |
mouse |
| Ejime A Chijiokwu, Eze K Nwangwa, Mega O Oyovwi, Alexander O Naiho, Victor Emojevwe, Ejiro P Ohwin, Prosper A Ehiwarior, Evelyn T Ojugbeli, Udoka S Nwabuoku, Onome B Oghenetega, Ofulue O Ogheneyom. Intermittent fasting and exercise therapy abates STZ-induced diabetotoxicity in rats through modulation of adipocytokines hormone, oxidative glucose metabolic, and glycolytic pathway. Physiological reports. vol 10. issue 20. 2022-10-28. PMID:36305681. |
the effects of starvation and honey on the oral glucose tolerance test, insulin tolerance test, adipocytokines, oxidative glucose metabolic enzymes, glycolytic enzymes, food intake, and body weight in rats with streptozotocin-induced diabetes were also investigated. |
2022-10-28 |
2023-08-14 |
rat |
| Esra Özkan, Yağmur Çetin-Taş, Emine Şekerdağ, Buket Yiğit, Narges Shomalizadeh, Selin Sapancı, Ceyda Ozler, Judy Kesibi, Ali B Kızılırmak, Murat Pekmez, Hale Yapıcı-Eser, Müjdat Zeybel, Serçin Karahüseyinoğlu, Yasemin Gürsoy-Özdemi. Hyperglycemia with or without insulin resistance triggers different structural changes in brain microcirculation and perivascular matrix. Metabolic brain disease. 2022-10-28. PMID:36305999. |
here, we investigated the high fat-high sucrose (hfhs) feeding model and streptozotocin-induced type-1 dm model to study the early effects of hyperglycemia with or without insulin resistance to demonstrate the brain microcirculatory changes, perivascular ecm alterations in histological sections and 3d-reconstructed cleared brain tissues. |
2022-10-28 |
2023-08-14 |
Not clear |
| Yuyao Xiang, Ruolan Huang, Yongliang Wang, Shanshan Han, Xiaochen Qin, Zhenzhen Li, Xu Wang, Yuqing Han, Tao Wang, Bo Xia, Jiangwei Wu, Gongshe Yan. Protocatechuic Acid Ameliorates High Fat Diet-Induced Obesity and Insulin Resistance in Mice. Molecular nutrition & food research. 2022-10-26. PMID:36285395. |
insulin resistance is a common feature of obesity and type 2 diabetes and partly results from an imbalance between food intake and energy expenditure. |
2022-10-26 |
2023-08-14 |
mouse |
| Tobias Kroon, Therese Hagstedt, Ida Alexandersson, Annett Ferm, Marie Petersson, Stefanie Maurer, Bader Zarrouki, Kristina Wallenius, Nicholas D Oakes, Jeremie Bouche. Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats. Science translational medicine. vol 14. issue 668. 2022-10-26. PMID:36288279. |
in line with increased hepatic insulin signaling, timing azd1656 to feeding resulted in robust activation of akt, mtor, and srebp-1c after glucose loading, pathways known to regulate vldl secretion and hepatic de novo lipogenesis. |
2022-10-26 |
2023-08-14 |
rat |
| Tobias Kroon, Therese Hagstedt, Ida Alexandersson, Annett Ferm, Marie Petersson, Stefanie Maurer, Bader Zarrouki, Kristina Wallenius, Nicholas D Oakes, Jeremie Bouche. Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats. Science translational medicine. vol 14. issue 668. 2022-10-26. PMID:36288279. |
in conclusion, intermittent azd1656 treatment timed to feeding periods promotes glucose disposal when needed the most, restores metabolic flexibility and hepatic insulin sensitivity, and thereby avoids hepatic steatosis. |
2022-10-26 |
2023-08-14 |
rat |
| Daeun Kim, Fumiaki Hanzawa, Hatsumi Shimizu, Shumin Sun, Miki Umeki, Saiko Ikeda, Satoshi Mochizuki, Hiroaki Od. Delayed feeding of a high-sucrose diet led to increased body weight by affecting the circadian rhythm of body temperature and hepatic lipid-metabolism genes in rats. The Journal of nutritional biochemistry. 2022-10-21. PMID:36270573. |
serum insulin concentration during the feeding period was higher than in the control rats, suggesting that slight insulin resistance was induced by the 4 h-delayed feeding. |
2022-10-21 |
2023-08-14 |
rat |
| Daeun Kim, Fumiaki Hanzawa, Hatsumi Shimizu, Shumin Sun, Miki Umeki, Saiko Ikeda, Satoshi Mochizuki, Hiroaki Od. Delayed feeding of a high-sucrose diet led to increased body weight by affecting the circadian rhythm of body temperature and hepatic lipid-metabolism genes in rats. The Journal of nutritional biochemistry. 2022-10-21. PMID:36270573. |
the oscillations of hepatic lipid and glucose metabolism-related gene expression were delayed by almost 2-4 h, and the clock genes were delayed by approximately 2 h. the 4 h-delayed feeding induced weight gain by affecting body temperature, insulin resistance, and circadian oscillation of lipid metabolism-related genes in rats fed a high-sucrose diet, suggesting that a high sucrose intake with breakfast skipping leads to obesity. |
2022-10-21 |
2023-08-14 |
rat |
| Kim Eerola, Francesco Longo, Thomas Reinbothe, Jennifer Richard, Olesya T Shevchouk, Lorena López-Ferreras, Devesh Mishra, Mohammed Asker, Johan Tolö, Caroline Miranda, Saliha Musovic, Charlotta S Olofsson, Patrik Rorsman, Karolina P Skibick. Hindbrain insulin controls feeding behavior. Molecular metabolism. 2022-10-16. PMID:36244663. |
hindbrain insulin controls feeding behavior. |
2022-10-16 |
2023-08-14 |
mouse |
| Pei-Yu Wang, Cong-Cong Jin, Chang Liu, Zhou-Jian Zhao, Hai-Yan Yan. PRL/PRLR Can Promote Insulin Resistance by Activating the JAK2/STAT5 Signaling Pathway. Computational and mathematical methods in medicine. vol 2022. 2022-10-14. PMID:36238467. |
although prolactin (prl) is known to affect food intake, weight gain, and insulin resistance, its effects on lipid metabolism and underlying mechanisms remain underinvestigated. |
2022-10-14 |
2023-08-14 |
Not clear |
| Stuart A Morgan, Laura L Gathercole, Zaki K Hassan-Smith, Jeremy Tomlinson, Paul M Stewart, Gareth G Laver. 11β-HSD1 contributes to age-related metabolic decline in male mice. The Journal of endocrinology. vol 255. issue 3. 2022-10-07. PMID:36205523. |
in this study, we have examined the impact of ageing on glucocorticoid metabolism, insulin tolerance, adiposity, muscle strength, and blood pressure in both wildtype (wt) and transgenic male mice with a global deletion of 11β-hsd1 (11β-hsd1-/-) following 4 months high-fat feeding. |
2022-10-07 |
2023-08-14 |
mouse |
| Genta Kakiyama, Kei Minowa, Daniel Rodriguez-Agudo, Rebecca Martin, Hajime Takei, Kuniko Mitamura, Shigeo Ikegawa, Suzuki Mitsuyoshi, Hiroshi Nittono, Michael Fuchs, Douglas M Heuman, Huiping Zhou, William M Panda. Coffee modulates insulin-HNF-4α-Cyp7b1 pathway and reduces oxysterol driven liver toxicity in a NAFLD mouse model. American journal of physiology. Gastrointestinal and liver physiology. 2022-10-04. PMID:36193897. |
the effects of coffee feeding on the insulin-hnf4α-cyp7b1 signaling pathway, whose dysregulation initiates and contributes to the onset and progression of nash as triggered by insulin resistance, offer mechanistic insight into approaches for the treatment of nafld. |
2022-10-04 |
2023-08-14 |
mouse |
| Lena J Tiedemann, Sebastian M Meyhöfer, Paul Francke, Judith Beck, Christian Büchel, Stefanie Brasse. Insulin sensitivity in mesolimbic pathways predicts and improves with weight loss in older dieters. eLife. vol 11. 2022-09-28. PMID:36170006. |
central insulin is critically involved in the regulation of hedonic feeding. |
2022-09-28 |
2023-08-14 |
human |