| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura Aponte Becerra, Anna Gavrieli, Faizan Khan, Peter Novak, Vasileios Lioutas, Long H Ngo, Vera Novak, Christos S Mantzoro. Daily intranasal insulin at 40IU does not affect food intake and body composition: A placebo-controlled trial in older adults over a 24-week period with 24-weeks of follow-up. Clinical nutrition (Edinburgh, Scotland). vol 42. issue 6. 2023-04-21. PMID:37084469. |
centrally administered insulin stimulates the reward system to reduce appetite in response to food intake in animal studies. |
2023-04-21 |
2023-08-14 |
human |
| Rajendran Harishkumar, Eva M Baranda-Alonso, William P Martin, Neil G Dochert. Impact of time-restricted feeding on kidney injury in male rats with experimental metabolic syndrome. Experimental physiology. 2023-04-19. PMID:37074338. |
changes in food intake, body weight, blood pressure, glucose tolerance, fasting plasma insulin, urinary excretion of c-peptide and renal injury biomarkers, liver and kidney histopathology and inflammation, and fibrosis-related renal gene expression will be assessed as secondary outcomes. |
2023-04-19 |
2023-08-14 |
rat |
| Jia Liu, Kevin W Aylor, Zhenqi Li. Liraglutide and Exercise Synergistically Attenuate Vascular Inflammation and Enhance Metabolic Insulin Action in Early Diet-induced Obesity. Diabetes. 2023-04-19. PMID:37074396. |
to examine whether exercise and glucagon-like peptide 1 (glp-1) receptor agonism, alone or in combination, modulate vascular and metabolic insulin actions during obesity development, we performed a euglycemic insulin clamp in adult male rats after 2 weeks of high-fat diet feeding with either access to running wheel (exercise), liraglutide, or both. |
2023-04-19 |
2023-08-14 |
rat |
| Takuma Yasuda, Norio Harada, Tomonobu Hatoko, Atsuhiko Ichimura, Eri Ikeguchi-Ogura, Yuki Murata, Naoki Wada, Sakura Kiyobayashi, Shunsuke Yamane, Akira Hirasawa, Nobuya Inagak. Inhibition of GPR120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding. American journal of physiology. Endocrinology and metabolism. 2023-04-19. PMID:37074989. |
inhibition of gpr120 signaling in intestine ameliorates insulin resistance and fatty liver under high-fat diet feeding. |
2023-04-19 |
2023-08-14 |
Not clear |
| Inna I Zorina, Natalia F Avrova, Irina O Zakharova, Alexander O Shpako. Prospects for the Use of Intranasally Administered Insulin and Insulin-Like Growth Factor-1 in Cerebral Ischemia. Biochemistry. Biokhimiia. vol 88. issue 3. 2023-04-19. PMID:37076284. |
insulin and insulin-like growth factor-1 (igf-1) play a key role in the brain functioning by regulating the growth, differentiation, and survival of neurons, neuronal plasticity, food intake, peripheral metabolism, and endocrine functions. |
2023-04-19 |
2023-08-14 |
Not clear |
| Anne Drougard, Eric H Ma, Vanessa Wegert, Ryan Sheldon, Ilaria Panzeri, Naman Vatsa, Stefanos Apostle, Luca Fagnocchi, Judith Schaf, Klaus Gossens, Josephine Völker, Shengru Pang, Anna Bremser, Erez Dror, Francesca Giacona, Sagar, Michael X Henderson, Marco Prinz, Russell G Jones, J Andrew Pospisili. A rapid microglial metabolic response controls metabolism and improves memory. bioRxiv : the preprint server for biology. 2023-04-17. PMID:37066282. |
chronic high-fat feeding triggers widespread metabolic dysfunction including obesity, insulin resistance, and diabetes. |
2023-04-17 |
2023-08-14 |
Not clear |
| Kristie I Aamodt, Alvin C Power. Peeling the onion: another layer in the regulation of insulin secretion. The Journal of clinical investigation. vol 133. issue 8. 2023-04-17. PMID:37066881. |
report that short-term dynamic changes in histone modifications regulated insulin secretion and acute β cell adaptations in response to fasting and feeding cycles. |
2023-04-17 |
2023-08-14 |
Not clear |
| Mutaz Amin, Rongling Wu, Claudia Gragnol. Novel Risk Variants in the Oxytocin Receptor Gene ( International journal of molecular sciences. vol 24. issue 7. 2023-04-13. PMID:37047255. |
recently, the oxytocin system was found to play other metabolic roles such as regulation of food intake, peripheral glucose uptake, and insulin sensitivity. |
2023-04-13 |
2023-08-14 |
Not clear |
| b' Katarina Mi\\xc5\\xa1, Ana-Marija Luli\\xc4\\x87, Toma\\xc5\\xbe Mar\\xc5\\xa1, Sergej Pirkmajer, Maja Katalini\\xc4\\x8. Insulin, dibutyryl-cAMP, and glucose modulate expression of patatin-like domain containing protein 7 in cultured human myotubes. Frontiers in endocrinology. vol 14. 2023-04-10. PMID:37033214.' |
expression of patatin-like phospholipase domain containing protein 7 (pnpla7), also known as neuropathy target esterase-related esterase (nre), a lysophospholipase, increases with fasting and decreases with feeding in mouse skeletal muscle, indicating it is regulated by insulin, counterregulatory hormones, such as glucocorticoids and catecholamines, and/or nutrients. |
2023-04-10 |
2023-08-14 |
mouse |
| Lucía Méndez, Silvia Muñoz, Lorena Barros, Bernat Miralles-Pérez, Marta Romeu, Sara Ramos-Romero, Josep Lluís Torres, Isabel Medin. Combined Intake of Fish Oil and D-Fagomine Prevents High-Fat High-Sucrose Diet-Induced Prediabetes by Modulating Lipotoxicity and Protein Carbonylation in the Kidney. Antioxidants (Basel, Switzerland). vol 12. issue 3. 2023-03-29. PMID:36978999. |
this study aims to investigate the mechanism underlying the induction of kidney dysfunction and the concomitant onset of insulin resistance by long-term high-fat and sucrose diet feeding in sprague dawley rats. |
2023-03-29 |
2023-08-14 |
rat |
| Vanessa Escolero, Laica Tolentino, Abdul Bari Muhammad, Abdul Hamid, Kabirullah Lutf. The Involvement of Endogenous Enkephalins in Glucose Homeostasis. Biomedicines. vol 11. issue 3. 2023-03-29. PMID:36979650. |
body weight and food intake were measured every week (n = 21-23 mice per genotype), and at the end of the 16-week exposure period, mice were tested using the oral glucose tolerance test (ogtt, n = 9 mice per genotype) and insulin tolerance test (n = 5 mice per genotype). |
2023-03-29 |
2023-08-14 |
mouse |
| Nicholas J Queen, Wei Huang, Suraj Komatineni, Anthony G Mansour, Run Xiao, Logan A Chrislip, Lei Ca. Social isolation exacerbates diet-induced obesity and peripheral inflammation in young male mice under thermoneutrality. iScience. vol 26. issue 3. 2023-03-14. PMID:36915694. |
we report si promotes weight gain, increases food intake, increases adiposity, worsens glycemic control, reduces insulin signaling, exacerbates systemic and adipose inflammatory responses, and induces a molecular signature within the hypothalamus. |
2023-03-14 |
2023-08-14 |
mouse |
| Hannah Gilliam-Vigh, Tina Jorsal, Sophie W Nielsen, Julie L Forman, Jens Pedersen, Steen S Poulsen, Tina Vilsbøll, Filip K Kno. Expression of Neurotensin and its Receptors Along the Intestinal Tract in Type 2 Diabetes Patients and Healthy Controls. The Journal of clinical endocrinology and metabolism. 2023-03-14. PMID:36916883. |
nts reduces food intake in rodents and may increase insulin release. |
2023-03-14 |
2023-08-14 |
Not clear |
| Xiaotong Sun, Ziwei Yu, Yuxin Xu, Shengdan Pu, Xinyuan Ga. The role of spexin in energy metabolism. Peptides. 2023-03-13. PMID:36914115. |
mature spexin peptides can exert various functions by activating galr2/3, such as inhibiting food intake, inhibiting lipid absorption, reducing body weight, and improving insulin resistance. |
2023-03-13 |
2023-08-14 |
Not clear |
| L Cattaneo, F Piccioli-Cappelli, A Minuti, E Trevis. Metabolic and physiological adaptations to first and second lactation in Holstein dairy cows: Postprandial patterns. Journal of dairy science. 2023-03-12. PMID:36907756. |
regardless of parity and stage of lactation, glucose, urea, β-hydroxybutyrate, and insulin peaked a few hours after the morning feeding, whereas nonesterified fatty acids decreased. |
2023-03-12 |
2023-08-14 |
Not clear |
| L Cattaneo, F Piccioli-Cappelli, A Minuti, E Trevis. Metabolic and physiological adaptations to first and second lactation in Holstein dairy cows: Postprandial patterns. Journal of dairy science. 2023-03-12. PMID:36907756. |
glucose and insulin were higher during the first lactation throughout the day, and the differences increased 9 h after feeding. |
2023-03-12 |
2023-08-14 |
Not clear |
| Kira V Derkach, Maxim A Gureev, Anastasia A Babushkina, Vladimir N Mikhaylov, Irina O Zakharova, Andrey A Bakhtyukov, Viktor N Sorokoumov, Alexander S Novikov, Mikhail Krasavin, Alexander O Shpakov, Irina A Balov. Dual PTP1B/TC-PTP Inhibitors: Biological Evaluation of 3-(Hydroxymethyl)cinnoline-4( International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36901928. |
in obese male wistar rats, a five-day administration of all studied compounds led to a decrease in body weight and food intake, improved glucose tolerance, attenuated hyperinsulinemia, hyperleptinemia and insulin resistance, and also compensatory increased expression of the ptp1b and tc-ptp genes in the liver. |
2023-03-11 |
2023-08-14 |
rat |
| Sebastián P Chapela, Daniel Simancas-Racines, Martha Montalvan, Evelyn Frias-Toral, Alison Simancas-Racines, Giovanna Muscogiuri, Luigi Barrea, Gerardo Sarno, Pablo I Martínez, María J Reberendo, Natalia D Llobera, Carlos A Stell. Signals for Muscular Protein Turnover and Insulin Resistance in Critically Ill Patients: A Narrative Review. Nutrients. vol 15. issue 5. 2023-03-11. PMID:36904071. |
some hormones regulate metabolism, such as insulin, insulin growth factor glucocorticoids, and growth hormone, whose secretion is affected by feeding states and inflammation. |
2023-03-11 |
2023-08-14 |
Not clear |
| Franziska Stumpf, Bettina Keller, Carla Gressies, Philipp Schuet. Inflammation and Nutrition: Friend or Foe? Nutrients. vol 15. issue 5. 2023-03-11. PMID:36904164. |
inflammation has been identified as a key driver for disease-related malnutrition, leading to anorexia, reduced food intake, muscle catabolism, and insulin resistance, which are stimulating a catabolic state. |
2023-03-11 |
2023-08-14 |
Not clear |
| Robert P Brumer, Juliana C Corrêa-Velloso, Samantha J Thomas, Oleta A Sandiford, Andrew P Thomas, Paula J Bartlet. Short-term high fat diet feeding of mice suppresses catecholamine-stimulated Ca The Journal of physiology. 2023-03-03. PMID:36864773. |
short-term high fat diet feeding of mice suppresses catecholamine-stimulated ca excess consumption of carbohydrates, fat, and calories leads to non-alcoholic fatty liver disease (nafld) and hepatic insulin resistance; major factors in the pathogenesis of type ii diabetes. |
2023-03-03 |
2023-08-14 |
mouse |