| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Kroon, Therese Hagstedt, Ida Alexandersson, Annett Ferm, Marie Petersson, Stefanie Maurer, Bader Zarrouki, Kristina Wallenius, Nicholas D Oakes, Jeremie Bouche. Chronotherapy with a glucokinase activator profoundly improves metabolism in obese Zucker rats. Science translational medicine. vol 14. issue 668. 2022-10-26. PMID:36288279. |
in conclusion, intermittent azd1656 treatment timed to feeding periods promotes glucose disposal when needed the most, restores metabolic flexibility and hepatic insulin sensitivity, and thereby avoids hepatic steatosis. |
2022-10-26 |
2023-08-14 |
rat |
| Daeun Kim, Fumiaki Hanzawa, Hatsumi Shimizu, Shumin Sun, Miki Umeki, Saiko Ikeda, Satoshi Mochizuki, Hiroaki Od. Delayed feeding of a high-sucrose diet led to increased body weight by affecting the circadian rhythm of body temperature and hepatic lipid-metabolism genes in rats. The Journal of nutritional biochemistry. 2022-10-21. PMID:36270573. |
serum insulin concentration during the feeding period was higher than in the control rats, suggesting that slight insulin resistance was induced by the 4 h-delayed feeding. |
2022-10-21 |
2023-08-14 |
rat |
| Daeun Kim, Fumiaki Hanzawa, Hatsumi Shimizu, Shumin Sun, Miki Umeki, Saiko Ikeda, Satoshi Mochizuki, Hiroaki Od. Delayed feeding of a high-sucrose diet led to increased body weight by affecting the circadian rhythm of body temperature and hepatic lipid-metabolism genes in rats. The Journal of nutritional biochemistry. 2022-10-21. PMID:36270573. |
the oscillations of hepatic lipid and glucose metabolism-related gene expression were delayed by almost 2-4 h, and the clock genes were delayed by approximately 2 h. the 4 h-delayed feeding induced weight gain by affecting body temperature, insulin resistance, and circadian oscillation of lipid metabolism-related genes in rats fed a high-sucrose diet, suggesting that a high sucrose intake with breakfast skipping leads to obesity. |
2022-10-21 |
2023-08-14 |
rat |
| Kim Eerola, Francesco Longo, Thomas Reinbothe, Jennifer Richard, Olesya T Shevchouk, Lorena López-Ferreras, Devesh Mishra, Mohammed Asker, Johan Tolö, Caroline Miranda, Saliha Musovic, Charlotta S Olofsson, Patrik Rorsman, Karolina P Skibick. Hindbrain insulin controls feeding behavior. Molecular metabolism. 2022-10-16. PMID:36244663. |
hindbrain insulin controls feeding behavior. |
2022-10-16 |
2023-08-14 |
mouse |
| Pei-Yu Wang, Cong-Cong Jin, Chang Liu, Zhou-Jian Zhao, Hai-Yan Yan. PRL/PRLR Can Promote Insulin Resistance by Activating the JAK2/STAT5 Signaling Pathway. Computational and mathematical methods in medicine. vol 2022. 2022-10-14. PMID:36238467. |
although prolactin (prl) is known to affect food intake, weight gain, and insulin resistance, its effects on lipid metabolism and underlying mechanisms remain underinvestigated. |
2022-10-14 |
2023-08-14 |
Not clear |
| Stuart A Morgan, Laura L Gathercole, Zaki K Hassan-Smith, Jeremy Tomlinson, Paul M Stewart, Gareth G Laver. 11β-HSD1 contributes to age-related metabolic decline in male mice. The Journal of endocrinology. vol 255. issue 3. 2022-10-07. PMID:36205523. |
in this study, we have examined the impact of ageing on glucocorticoid metabolism, insulin tolerance, adiposity, muscle strength, and blood pressure in both wildtype (wt) and transgenic male mice with a global deletion of 11β-hsd1 (11β-hsd1-/-) following 4 months high-fat feeding. |
2022-10-07 |
2023-08-14 |
mouse |
| Genta Kakiyama, Kei Minowa, Daniel Rodriguez-Agudo, Rebecca Martin, Hajime Takei, Kuniko Mitamura, Shigeo Ikegawa, Suzuki Mitsuyoshi, Hiroshi Nittono, Michael Fuchs, Douglas M Heuman, Huiping Zhou, William M Panda. Coffee modulates insulin-HNF-4α-Cyp7b1 pathway and reduces oxysterol driven liver toxicity in a NAFLD mouse model. American journal of physiology. Gastrointestinal and liver physiology. 2022-10-04. PMID:36193897. |
the effects of coffee feeding on the insulin-hnf4α-cyp7b1 signaling pathway, whose dysregulation initiates and contributes to the onset and progression of nash as triggered by insulin resistance, offer mechanistic insight into approaches for the treatment of nafld. |
2022-10-04 |
2023-08-14 |
mouse |
| Lena J Tiedemann, Sebastian M Meyhöfer, Paul Francke, Judith Beck, Christian Büchel, Stefanie Brasse. Insulin sensitivity in mesolimbic pathways predicts and improves with weight loss in older dieters. eLife. vol 11. 2022-09-28. PMID:36170006. |
central insulin is critically involved in the regulation of hedonic feeding. |
2022-09-28 |
2023-08-14 |
human |
| Greg Bigford, Angela Szeto, Andrew J Darr, Placido Illiano, Ronald Zambrano, Armando J Mendez, Mark Nas. Characterization of Gastrointestinal Hormone Dysfunction and Metabolic Pathophysiology in Experimental Spinal Cord Injury. Journal of neurotrauma. 2022-09-28. PMID:36170594. |
here we investigate gene-expression and physiological changes in gi peptides and hormones, as well as changes in physiological response to feeding, glucose and insulin challenge and evaluate gi tissue cytoarchitecture following experimental sci. |
2022-09-28 |
2023-08-14 |
mouse |
| Xiaojuan Zhang, Feng Guo, Dujuan Cao, Yinan Yan, Ning Zhang, Kaili Zhang, Xinyi Li, Prashant Kumar, Xiaojuan Zhan. Neuroprotective Effect of Ponicidin Alleviating the Diabetic Cognitive Impairment: Regulation of Gut Microbiota. Applied biochemistry and biotechnology. 2022-09-26. PMID:36155887. |
ponicidin significantly (p < 0.001) repressed the glucose level and water food intake and improved the body weight and plasma insulin. |
2022-09-26 |
2023-08-14 |
rat |
| Bastian Ramms, Dennis P Pollow, Han Zhu, Chelsea Nora, Austin R Harrington, Ibrahim Omar, Philip L S M Gordts, Matthew Wortham, Maike Sande. Systemic LSD1 Inhibition Prevents Aberrant Remodeling of Metabolism in Obesity. Diabetes. 2022-09-26. PMID:36162056. |
we show that systemic administration of an lsd1 inhibitor (gsk-lsd1) reduces food intake and body weight, ameliorates non-alcoholic fatty liver disease (nafld), and improves insulin sensitivity and glycemic control in mouse models of obesity. |
2022-09-26 |
2023-08-14 |
mouse |
| Nan Li, Haiyan Shi, Qiaofeng Guo, Yanming Gan, Yuhang Zhang, Jiajie Jia, Liang Zhang, Yue Zho. Aerobic Exercise Prevents Chronic Inflammation and Insulin Resistance in Skeletal Muscle of High-Fat Diet Mice. Nutrients. vol 14. issue 18. 2022-09-23. PMID:36145106. |
body weight, fasting blood glucose, food intake levels, and glucose and insulin tolerance were evaluated. |
2022-09-23 |
2023-08-14 |
mouse |
| Aline Bassetto Okamura, Vivian Siqueira Santos Gonçalves, Kênia Mara Baiocchi de Carvalh. School Feeding as a Protective Factor against Insulin Resistance: The Study of Cardiovascular Risks in Adolescents (ERICA). International journal of environmental research and public health. vol 19. issue 17. 2022-09-09. PMID:36078265. |
school feeding as a protective factor against insulin resistance: the study of cardiovascular risks in adolescents (erica). |
2022-09-09 |
2023-08-14 |
Not clear |
| Aline Bassetto Okamura, Vivian Siqueira Santos Gonçalves, Kênia Mara Baiocchi de Carvalh. School Feeding as a Protective Factor against Insulin Resistance: The Study of Cardiovascular Risks in Adolescents (ERICA). International journal of environmental research and public health. vol 19. issue 17. 2022-09-09. PMID:36078265. |
the objective of this study was to use erica data from adolescents from brazilian public schools to investigate the role of school feeding in insulin resistance markers. |
2022-09-09 |
2023-08-14 |
Not clear |
| Aline Bassetto Okamura, Vivian Siqueira Santos Gonçalves, Kênia Mara Baiocchi de Carvalh. School Feeding as a Protective Factor against Insulin Resistance: The Study of Cardiovascular Risks in Adolescents (ERICA). International journal of environmental research and public health. vol 19. issue 17. 2022-09-09. PMID:36078265. |
school feeding was positively associated with an insulin resistance marker, decreasing by 0.135 units of homa-ir (95% ci; -0.19, -0.08), 0.469 μu/l of insulin levels (95% ci; -0.66, -0.28), and 0.634 mg/dl of blood glucose (95% ci; -0.87, -0.39). |
2022-09-09 |
2023-08-14 |
Not clear |
| Aline Bassetto Okamura, Vivian Siqueira Santos Gonçalves, Kênia Mara Baiocchi de Carvalh. School Feeding as a Protective Factor against Insulin Resistance: The Study of Cardiovascular Risks in Adolescents (ERICA). International journal of environmental research and public health. vol 19. issue 17. 2022-09-09. PMID:36078265. |
school feeding was positively associated with insulin resistance variables, demonstrating the potential of planned meals in the school environment to serve as a health promoter for the adolescent population. |
2022-09-09 |
2023-08-14 |
Not clear |
| Lara Ribeiro-Parenti, Hounayda El Jindi, Alexandra Willemetz, Matthieu Siebert, Nathalie Kapel, Johanne Le Beyec, André Bado, Maude Le Gal. Shortening the Biliopancreatic Limb Length of One Anastomosis Gastric Bypass Maintains Glucose Homeostasis Improvement with Limited Weight Loss. Journal of clinical medicine. vol 11. issue 17. 2022-09-09. PMID:36078906. |
body weight and food intake were monitored over 30 weeks, and rats underwent oral glucose and insulin tolerance tests with a pancreatic and gut hormone secretion assay. |
2022-09-09 |
2023-08-14 |
rat |
| Xuejiao Lu, Zhihong Fan, Anshu Liu, Rui Liu, Xinling Lou, Jiahui H. Extended Inter-Meal Interval Negatively Impacted the Glycemic and Insulinemic Responses after Both Lunch and Dinner in Healthy Subjects. Nutrients. vol 14. issue 17. 2022-09-09. PMID:36079874. |
this study aimed to investigate the glycemic and insulinemic effects of lunch timing based on a fixed feeding window, and the effects of apple preload on postprandial glucose and insulin responses after nutrient-balanced lunch and the subsequent high-fat dinner in healthy participants. |
2022-09-09 |
2023-08-14 |
human |
| Michael A Nauck, David A D'Alessi. Tirzepatide, a dual GIP/GLP-1 receptor co-agonist for the treatment of type 2 diabetes with unmatched effectiveness regrading glycaemic control and body weight reduction. Cardiovascular diabetology. vol 21. issue 1. 2022-09-01. PMID:36050763. |
tirzepatide is an acylated peptide engineered to activate the gip and glp-1 receptors, key mediators of insulin secretion that are also expressed in regions of the brain that regulate food intake. |
2022-09-01 |
2023-08-14 |
human |
| Ashley Selman, Scott Burns, Arubala P Reddy, John Culberson, P Hemachandra Redd. The Role of Obesity and Diabetes in Dementia. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012526. |
this inflammatory state leads to the dysregulation of food intake and insulin resistance. |
2022-08-26 |
2023-08-14 |
Not clear |