| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie E Finnell, Carrie R Ferrari. Intra-NAc insulin reduces the motivation for food and food intake without altering cue-triggered food-seeking. Physiology & behavior. 2022-06-26. PMID:35753434. |
in humans and rodents, actions of insulin in the brain decrease food intake. |
2022-06-26 |
2023-08-14 |
rat |
| Julie E Finnell, Carrie R Ferrari. Intra-NAc insulin reduces the motivation for food and food intake without altering cue-triggered food-seeking. Physiology & behavior. 2022-06-26. PMID:35753434. |
here we determined how intra-nac insulin affects conditioned approach (a measure of cue-triggered food-seeking), free food intake, and the motivation to obtain food in hungry rats using pavlovian and instrumental approaches. |
2022-06-26 |
2023-08-14 |
rat |
| Julie E Finnell, Carrie R Ferrari. Intra-NAc insulin reduces the motivation for food and food intake without altering cue-triggered food-seeking. Physiology & behavior. 2022-06-26. PMID:35753434. |
these data are discussed in light of insulin's role in the regulation of feeding, and its dysregulation by obesity. |
2022-06-26 |
2023-08-14 |
rat |
| Sorina Andreea Anghel, Rodica Aura Badea, Gabriela Chiritoiu, David Sebastian Patriche, Petruta Ramona Alexandru, Florentina Pen. Novel luciferase-based GLP-1 reporter assay reveals naturally-occurring secretagogues. British journal of pharmacology. 2022-06-23. PMID:35736785. |
it is secreted by enteroendocrine cells in response to feeding, and, in turn, acts as a critical regulator of insulin release. |
2022-06-23 |
2023-08-14 |
Not clear |
| K M Pascutti, A L O'Kell, R C Hill, R A Castro, M E Salute, C Gilo. The effect of capromorelin on glycemic control in healthy dogs. Domestic animal endocrinology. vol 81. 2022-06-11. PMID:35689953. |
on d 1 of each treatment, blood glucose (bg), insulin, glucagon, glucose-dependent insulinotropic peptide (gip), and glucagon-like peptide-1 (glp-1) concentrations were measured before drug administration, then before and 30-120 min after feeding a glucose-rich diet (ensure plus, 21 kcal/kg). data were analyzed as a 2-period crossover design using generalized least squares estimation. capromorelin administration increased mean 48 h ig by10% and mean bg by 20% at 90 and 120 min post-prandially (p < 0.0001). |
2022-06-11 |
2023-08-14 |
Not clear |
| Omar Al-Massadi, Paolo Parini, Johan Fernø, Serge Luquet, Mar Quiñone. Metabolic actions of the growth hormone-insulin growth factor-1 axis and its interaction with the central nervous system. Reviews in endocrine & metabolic disorders. 2022-06-10. PMID:35687272. |
growth hormone together with insulin growth factor-1 perform metabolic adjustments, including regulation of food intake, energy expenditure, and glycemia. |
2022-06-10 |
2023-08-14 |
Not clear |
| Lauren Carmichael, Michelle A Keske, Andrew C Betik, Lewan Parker, Barbara Brayner, Katherine M Roberts-Thomson, Glenn D Wadley, D Lee Hamilton, Gunveen Kau. Is vascular insulin resistance an early step in diet-induced whole-body insulin resistance? Nutrition & diabetes. vol 12. issue 1. 2022-06-08. PMID:35676248. |
studies suggest that in diet-induced insulin-resistant rodents, insulin-mediated skeletal muscle microvascular blood flow is impaired post-short-term high fat feeding, and this occurs before the development of myocyte or whole-body insulin resistance. |
2022-06-08 |
2023-08-14 |
Not clear |
| Ming Tong, Jason L Ziplow, Princess Mark, Suzanne M de la Mont. Dietary Soy Prevents Alcohol-Mediated Neurocognitive Dysfunction and Associated Impairments in Brain Insulin Pathway Signaling in an Adolescent Rat Model. Biomolecules. vol 12. issue 5. 2022-05-28. PMID:35625605. |
previous studies have suggested that early treatment with insulin sensitizers or dietary soy could reduce or prevent the long-term adverse effects of chronic ethanol feeding. |
2022-05-28 |
2023-08-13 |
rat |
| Weiyi Qu, Ze Chen, Xing Hu, Toujun Zou, Yongping Huang, Yanyan Zhang, Yufeng Hu, Song Tian, Juan Wan, Rufang Liao, Lan Bai, Jinhua Xue, Yi Ding, Manli Hu, Xiao-Jing Zhang, Xin Zhang, Jingjing Zhao, Xu Cheng, Zhi-Gang She, Hongliang L. Profound Perturbation in the Metabolome of a Canine Obesity and Metabolic Disorder Model. Frontiers in endocrinology. vol 13. 2022-05-27. PMID:35620391. |
dogs fed a hfd showed a gradual body weight increase during the feeding period and had hyperlipidemia, increased leukocyte counts, and impaired insulin sensitivity at week 24. |
2022-05-27 |
2023-08-13 |
Not clear |
| b' Petra Honzlov\\xc3\\xa1, Zuzana Novosadov\\xc3\\xa1, Pavel Houdek, Martin Sl\\xc3\\xa1dek, Alena Sumov\\xc3\\xa. Misaligned feeding schedule elicits divergent circadian reorganizations in endo- and exocrine pancreas clocks. Cellular and molecular life sciences : CMLS. vol 79. issue 6. 2022-05-27. PMID:35622158.' |
we exposed rats to a reversed restricted feeding regimen (rrf) for 10 or 20 days and analyzed locomotor activity, daily profiles of hormone levels (insulin, glucagon, and corticosterone) in plasma, and clock gene expression in the liver and endocrine and exocrine pancreas. |
2022-05-27 |
2023-08-13 |
rat |
| Hylton E Molzof, Courtney M Peterson, S Justin Thomas, Gabrielle F Gloston, Russell L Johnson, Karen L Gambl. Nightshift Work and Nighttime Eating Are Associated With Higher Insulin and Leptin Levels in Hospital Nurses. Frontiers in endocrinology. vol 13. 2022-05-26. PMID:35615722. |
we examined whether insulin and leptin levels differ between dayshift versus nightshift nurses, as well as explored whether the timing of food intake modulates these effects in nightshift workers. |
2022-05-26 |
2023-08-13 |
Not clear |
| Samah Alharb. Exogenous administration of unacylated ghrelin attenuates hepatic steatosis in high-fat diet-fed rats by modulating glucose homeostasis, lipogenesis, oxidative stress, and endoplasmic reticulum stress. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 151. 2022-05-20. PMID:35594708. |
with no change in insulin levels, and in a dose-dependent manner, treatment with uag to hfd rats attenuated the gain in food intake, body weights, and liver weights, lowered fasting glucose levels, prevented hepatic cytoplasmic vacuolization, and reduced serum and hepatic levels of cholesterol, triglycerides, and free fatty acids. |
2022-05-20 |
2023-08-13 |
rat |
| Tarik Khouya, Mhamed Ramchoun, Abdelbassat Hmidani, Souliman Amrani, Mohamed Benlyas, Fatima Kasbi Chadli, Khadija Ouguerram, Chakib Ale. Effect of supplementation with polyphenol extract of Thymus atlanticus on paraoxonase-1 activity, insulin resistance, and lipid profile in high-fat diet-fed hamsters. Journal of food biochemistry. 2022-05-16. PMID:35575425. |
results showed that the supplementation of hfd with pp significantly (p < .001) reduced the levels of mda and ldl cholesterol, restored insulin level, and increased the activities of serum paraoxonase-1 and hdl cholesterol levels, but did not affect (p > .05) the activity of superoxide dismutase and glutathione peroxidase when compared with the group feeding hfd alone. |
2022-05-16 |
2023-08-13 |
Not clear |
| Jaime Pignatelli, M Estrella Fernandez de Sevilla, Jacob Sperber, Daniel Horrillo, Gema Medina-Gomez, Ignacio Torres Alema. Insulin-like Growth Factor I Couples Metabolism with Circadian Activity through Hypothalamic Orexin Neurons. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563069. |
recently, insulin and the closely related insulin-like growth factor i (igf-i) were shown to entrain feeding patterns with circadian rhythms. |
2022-05-14 |
2023-08-13 |
mouse |
| Anna Mietelska-Porowska, Justyna Domańska, Andrew Want, Angelika Więckowska-Gacek, Dominik Chutorański, Maciej Koperski, Urszula Wojd. Induction of Brain Insulin Resistance and Alzheimer's Molecular Changes by Western Diet. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563135. |
long-term wd feeding leads to insulin resistance, postulated as a risk factor for alzheimer's disease (ad). |
2022-05-14 |
2023-08-13 |
mouse |
| Pengfei Hou, Wenting Dai, Yanshan Jin, Fengqi Zhao, Jianxin Liu, Hongyun Li. Maternal exposure to di-2-ethylhexyl phthalate (DEHP) depresses lactation capacity in mice. The Science of the total environment. 2022-05-13. PMID:35550907. |
we observed the reduced food intake with elevated blood leptin and the decreased milk yield as well as the reduced levels of serum prolactin, growth hormone, insulin-like growth factor 1 and insulin after exposed to dehp. |
2022-05-13 |
2023-08-13 |
mouse |
| Joseph T Blumer, Jee Young Han, Keelin Ricciardi, Samuel T Saghafi, Anya Beric, Grace H Yang, Sukanya Lodh, Danielle A Fontaine, Dawn B Davi. Loss of Transcription Factor 19 (Tcf19) Impacts Metabolic Response to Stress. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35551849. |
female mice, less susceptible to diet induced hyperglycemia, were stressed with long-term high fat high sucrose diet (hfhs) feeding to induce insulin resistance. |
2022-05-13 |
2023-08-13 |
mouse |
| Darren Mehay, Sarah Bingaman, Yuval Silberman, Amy C Arnol. Angiotensin-(1-7) Mas Receptors Localized to Proopiomelanocortin Neurons Tonically Regulate Insulin Sensitivity. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35560928. |
in particular, we found that masr are highly colocalized with proopiomelanocortin (pomc)-containing neurons in this brain region, neurons which when activated reduce food intake and increase energy expenditure to promote weight loss as well as improve insulin sensitivity. |
2022-05-13 |
2023-08-13 |
mouse |
| Vadivel Mani, Ramya Badrachalam, Sharon Nallathannikulam Shanmugam, Manikandan Balraj, Revathi Kasthuri, Anandhi Danavel, Shyamaladevi Bab. Effect of β-Caryophyllene on insulin resistance in skeletal muscle of high fat diet and fructose-induced type-2 diabetic rats. Bioinformation. vol 17. issue 8. 2022-05-11. PMID:35540699. |
high fat diet feeding results in hyperglycemia and insulin resistance, which is a major pathological feature of type-2 diabetes mellitus. |
2022-05-11 |
2023-08-13 |
rat |
| Romil Saxena, Mehdi Nassiri, Xiao-Ming Yin, Núria Morra. Insights from a high-fat diet fed mouse model with a humanized liver. PloS one. vol 17. issue 5. 2022-05-09. PMID:35533183. |
here we explored the feasibility of using one of these models (cdna-upa/scid) to recapitulate obesity, insulin resistance and nafld upon feeding a western-style diet. |
2022-05-09 |
2023-08-13 |
mouse |