| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fangluo Chen, Dylan C Sarver, Muzna Saqib, Mingqi Zhou, Susan Aja, Marcus M Seldin, G William Won. CTRP13 ablation improves systemic glucose and lipid metabolism. Molecular metabolism. 2023-10-16. PMID:37844630. |
we previously showed that ctrp13/c1ql3, a secreted protein of the c1q family, can improve glucose metabolism and insulin action in vitro and reduce food intake and body weight in mice when centrally delivered. |
2023-10-16 |
2023-11-08 |
mouse |
| Chen Lei, Jing Wang, Xin Li, Yuan-Yuan Mao, Jian-Qun Ya. Changes of insulin receptors in high fat and high glucose diet mice with insulin resistance. Adipocyte. vol 12. issue 1. 2023-10-13. PMID:37830511. |
as a result, compared with the nf group, the hf group mice had increased weight, fbg, insulin and ir index after 6-week of feeding as well as a worse performance in the insulin tolerance test and h&e staining showed fatty liver-like changes after 12-week of feeding, exhibited lower expression of insr, irs-1 and irs-2 in the liver of mice at 6 and 12 weeks. |
2023-10-13 |
2023-10-15 |
mouse |
| Gul Eyikudamaci, Hasan Ege, Nihal Ensen, Nermin Yelme. Role of insulin resistance and leptin in the effect of intermittent feeding with a high-protein ketogenic diet on body composition in rats. Nutrition (Burbank, Los Angeles County, Calif.). vol 117. 2023-10-13. PMID:37832180. |
role of insulin resistance and leptin in the effect of intermittent feeding with a high-protein ketogenic diet on body composition in rats. |
2023-10-13 |
2023-10-15 |
rat |
| D Patel J, A Vikal, V Kumar, A Ahmad, K Sharma, K Ash. THE MICROBIOME AND METABOLIC DISORDERS: THE LINK BETWEEN THE GUT MICROBIOTA AND METABOLIC SYNDROME. Georgian medical news. issue 340-341. 2023-10-08. PMID:37805890. |
from a metabolic perspective, the gut microbiota can affect processes like lipid accumulation, lipopolysaccharide satisfied, and short-chain fatty acid synthesis, all of which have an effect on food intake, inflammatory reactions, and insulin signaling. |
2023-10-08 |
2023-10-15 |
human |
| Qinghao Meng, Ying Li, Yidong Xu, Yiwen Wan. Acetobacter and lactobacillus alleviate the symptom of insulin resistance by blocking the JNK-JAK/STAT pathway in Drosophila melanogaster. Biochimica et biophysica acta. Molecular basis of disease. 2023-09-29. PMID:37774935. |
furthermore, we observed that symptoms of insulin resistance were alleviated by feeding flies with acetobacter or lactobacillus, indicating that these microorganisms play an essential role in maintaining blood sugar homeostasis in flies. |
2023-09-29 |
2023-10-07 |
drosophila_melanogaster |
| Samnhita Raychaudhuri, Md Shahinozzaman, Si Fan, Opeyemi Ogedengbe, Ujjwol Subedi, Diana N Oband. Resistance to Diet Induced Visceral Fat Accumulation in C57BL/6NTac Mice Is Associated with an Enriched Lactococcus in the Gut Microbiota and the Phenotype of Immune B Cells in Intestine and Adipose Tissue. Microorganisms. vol 11. issue 9. 2023-09-28. PMID:37763997. |
we singly housed them for three weeks, monitored food intake and determined insulin resistance, fat accumulation, and small intestinal and fecal gut microbial community membership and structure. |
2023-09-28 |
2023-10-07 |
mouse |
| Lauren A Jones, Emily W Sun, Amanda L Lumsden, Daniel W Thorpe, Rochelle A Peterson, Dayan De Fontgalland, Luigi Sposato, Philippa Rabbitt, Paul Hollington, David A Wattchow, Damien J Keatin. Alterations in GLP-1 and PYY release with aging and body mass in the human gut. Molecular and cellular endocrinology. 2023-09-22. PMID:37739120. |
while much is known about the effects of these hormones on metabolism, insulin secretion and food intake, less is understood about their secretion from human intestinal tissue. |
2023-09-22 |
2023-10-07 |
human |
| Chu-Mao Chen, Xiao-Qian Meng, Hong Zhu, Ting Liu, Yuan Liu, Lu-Jun Zhou, Guo-Dong Zhu, Xiao-Bei Chen, Xu-Guang Guo, Sheng-Zhong Dua. Brown adipocyte mineralocorticoid receptor deficiency impairs metabolic regulation in diet-induced obese mice. Journal of lipid research. 2023-09-21. PMID:37734559. |
after 8 weeks of high fat diet (hfd) feeding, bat mr knockout (bmrko) mice manifested significantly increased body weight, fat mass, serum fasting glucose and impaired glucose homeostasis compared to littermate control (lc) mice, although insulin resistance and fasting serum insulin were not significantly changed. |
2023-09-21 |
2023-10-07 |
mouse |
| b' Anna Mengr, Veronika Strnadov\\xc3\\xa1, \\xc5\\xa0t\\xc4\\x9bp\\xc3\\xa1n Strnad, Vladim\\xc3\\xadr Vrkoslav, Helena Pelantov\\xc3\\xa1, Marek Kuzma, Thomas Comptdaer, Blanka \\xc5\\xbdelezn\\xc3\\xa1, Jaroslav Kune\\xc5\\xa1, Marie-Christine Galas, Andrea Pa\\xc4\\x8desov\\xc3\\xa1, Lenka Malet\\xc3\\xadnsk\\xc3\\xa. Feeding High-Fat Diet Accelerates Development of Peripheral and Central Insulin Resistance and Inflammation and Worsens AD-like Pathology in APP/PS1 Mice. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686722.' |
feeding high-fat diet accelerates development of peripheral and central insulin resistance and inflammation and worsens ad-like pathology in app/ps1 mice. |
2023-09-09 |
2023-10-07 |
mouse |
| Changbao Sun, Ang Li, Huan Wang, Jiage Ma, Juncai Ho. Positive Regulation of Acetate in Adipocyte Differentiation and Lipid Deposition in Obese Mice. Nutrients. vol 15. issue 17. 2023-09-09. PMID:37686768. |
to further develop this scientific point, obese mice on a high-fat diet were given an intragastric administration of acetate for 8 weeks and mouse adipose mesenchymal stem cells (mamscs) were treated with acetate for 24 h. the results showed that the body weight, food intake, lee's index, adipose tissue coefficient, liver index, blood lipid levels, insulin resistance, pro-inflammatory factors levels and fatty lesions in liver and adipose tissue in obese mice treated with acetate increased markedly, while anti-inflammatory factors levels and liver function decreased significantly ( |
2023-09-09 |
2023-10-07 |
mouse |
| Ming Yeh Lee, Anna L Gloyn, David M Maahs, Priya Prahala. Management of Neonatal Diabetes due to a Case reports in endocrinology. vol 2023. 2023-09-04. PMID:37664823. |
management of hyperglycemia in neonates with subcutaneous insulin is challenging because of frequent feeding, variable quantity of milk intake with each feed, low insulin dose requirements, and high risk for hypoglycemia and associated complications in this population. |
2023-09-04 |
2023-09-07 |
Not clear |
| Shweta Tandon, Surajit Sarka. Glutamine stimulates the S6K/4E-BP branch of insulin signalling pathway to mitigate human poly(Q) disorders in Nutritional neuroscience. 2023-09-02. PMID:37658796. |
glutamine stimulates the s6k/4e-bp branch of insulin signalling pathway to mitigate human poly(q) disorders in since, the s6k/4e-bp sub-pathway can be stimulated by various amino acids; we extended our investigation to examine if oral feeding of amino acids delivers rescue against human poly(q) toxicity in |
2023-09-02 |
2023-09-07 |
human |
| Marine Monney, François R Jornayvaz, Karim Garian. GLP-1 receptor agonists effect on cognitive function in patients with and without type 2 diabetes. Diabetes & metabolism. 2023-09-01. PMID:37657738. |
glp-1 receptor agonist has a peripheral and a central action, including stimulation of glucose-dependent insulin secretion and insulin biosynthesis, inhibition of glucagon secretion and gastric emptying, and inhibition of food intake. |
2023-09-01 |
2023-09-07 |
Not clear |
| Joao Carlos Ribeiro-Silva, Vinicius Bermond Marques, Leonardo Dos Santo. Effects of Dipeptidyl Peptidase 4 Inhibition on the Endothelial Control of the Vascular Tone. American journal of physiology. Cell physiology. 2023-08-29. PMID:37642237. |
dipeptidyl peptidase 4 (dpp4) is a serine protease known to cleave incretin hormones, which stimulate insulin secretion after food intake, a fact that supported the development of its inhibitors (dpp4i, or gliptins) for the treatment of type 2 diabetes mellitus. |
2023-08-29 |
2023-09-07 |
human |
| Asma K Omar, Lance C Li Puma, Luke A Whitcomb, Briana D Risk, Aria C Witt, Jason E Bruemmer, Quinton A Winger, Gerrit J Bouma, Adam J Chicc. High-fat diet during pregnancy promotes fetal skeletal muscle fatty acid oxidation and insulin resistance in an ovine model. American journal of physiology. Regulatory, integrative and comparative physiology. 2023-08-29. PMID:37642284. |
these results indicate that maternal high-fat feeding shifts fetal skeletal muscle metabolism toward a greater capacity for fatty acid over glucose utilization and favors prenatal development of insulin resistance, which may predispose offspring to metabolic syndrome later in life. |
2023-08-29 |
2023-09-07 |
Not clear |
| Sara Zakarneh, Yasmin Khial, Reema Tayye. Dietary Factors Associated with Glycemic Control in Children and Adolescents with Type 1 Diabetes. Current pediatric reviews. 2023-08-23. PMID:37608667. |
managing t1dm requires regular insulin administration, adjustment of food intake and exercise, and a comprehensive understanding of nutrition. |
2023-08-23 |
2023-09-07 |
Not clear |
| Sara M Mohamed, Tahany A A Aly, Marwa S Khattab, Emam A Abdel-Rahim, Ammar Al-Farg. Pathological and biochemical evaluation of radish microgreen on diabetes and aflatoxicosis in rats. Environmental science and pollution research international. 2023-08-22. PMID:37608169. |
rm feeding restored glucose level to normal but did not alter insulin level. |
2023-08-22 |
2023-09-07 |
rat |
| Xing Wang, Dongmei Long, Xianghong Hu, Nan Gu. Gentiopicroside modulates glucose homeostasis in high-fat-diet and streptozotocin-induced type 2 diabetic mice. Frontiers in pharmacology. vol 14. 2023-08-21. PMID:37601073. |
the results showed that gps supplementation discernibly decreased blood glucose levels, food intake and water consumption, ameliorated glucose intolerance, abnormal pyruvate tolerance, insulin resistance and dyslipidemia. |
2023-08-21 |
2023-09-07 |
mouse |
| Ji Hyeon Kang, Hyung Sik Kim, Seon Hyang Park, Ye Seon Kim, Yoe-Sik Ba. WKYMVm ameliorates obesity by improving lipid metabolism and leptin signalling. Journal of cellular and molecular medicine. 2023-08-21. PMID:37603580. |
administration of wkymvm into high fat diet (hfd)-induced obese mice significantly attenuated body weight gain, food intake and increased insulin sensitivity. |
2023-08-21 |
2023-09-07 |
mouse |
| Arwa Ali Zarie, Magdi A Osman, Ghedeir M Alshammari, Amro B Hassan, Abu ElGasim Ahmed Yagoub, Mohammed Abdo Yahy. Saudi date cultivars' seed extracts inhibit developing hepatic steatosis in rats fed a high-fat diet. Saudi journal of biological sciences. vol 30. issue 9. 2023-08-17. PMID:37588573. |
accordingly, feeding rats hfd significantly increased body and liver weights, hepatic and serum lipid levels, glucose, insulin, homa-ir, liver function enzymes, and inflammation markers, and decreased oxidative stress enzymes. |
2023-08-17 |
2023-09-07 |
rat |