| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shihui Mei, Guangxia He, Tiantian Zhang, Ze Chen, Rong Zhang, Yixiao Liao, Mingming Zhu, Duhan Xu, Yanjuan Shen, Bijun Zhou, Kaigong Wang, Chunmei Wang, Chao Chen, Erpeng Zhu, Zhentao Chen. Effect of feeding fermented distiller's grains diets on immune status and metabolomics of spleen and mesenteric lymph nodes in finishing cattle. Journal of proteomics. 2024-02-07. PMID:38325729. |
in this study, we found that feeding fdg may promote spleen development by regulating choline metabolism in cancer, glycerophospholipid metabolism, biosynthesis of unsaturated fatty acids and insulin resistance metabolic pathways, and may affect mln development by regulating choline metabolism in cancer. |
2024-02-07 |
2024-02-10 |
cattle |
| Sing-Young Chen, Aiden Telfser, Ellen Olzomer, Calum Vancuylenberg, Mingyan Zhou, Martina Beretta, Catherine Li, Stephanie Alexopoulos, Nigel Turner, Frances Byrne, Webster L Santos, Kyle Hoeh. Beneficial effects of simultaneously targeting calorie intake and calorie efficiency in diet-induced obese mice. Clinical science (London, England : 1979). 2024-02-05. PMID:38315575. |
semaglutide is an anti-diabetes and weight loss drug that decreases food intake, slows gastric emptying, and increases insulin secretion. |
2024-02-05 |
2024-02-09 |
mouse |
| Meri Rogava, Tyler J Aprati, Wei-Yu Chi, Johannes C Melms, Clemens Hug, Stephanie H Davis, Ethan M Earlie, Charlie Chung, Sachin K Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T Gibney, Oliver J Schmitz, Megan Sykes, Rémi J Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F Bakhoum, Semir Beyaz, Lewis C Cantley, Peter K Sorger, Sven W Meckelmann, Alpaslan Tasdogan, David Liu, Ashley M Laughney, Benjamin Iza. Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature cancer. 2024-01-29. PMID:38286827. |
we found that systemic pi3k inhibition exacerbated lm burden in mice injected with pip4k2c-deficient cancer cells through host-mediated increase in hepatic insulin levels; however, this circuit could be broken by concurrent administration of an sglt2 inhibitor or feeding of a ketogenic diet. |
2024-01-29 |
2024-02-01 |
mouse |
| Endika Varela-Martínez, María Gracia Luigi-Sierra, Dailu Guan, Manel López-Béjar, Encarna Casas, Sergi Olvera-Maneu, Jaume Gardela, Maria Jesús Palomo, Uchebuchi Ike Osuagwuh, Uchechi Linda Ohaneje, Emilio Mármol-Sanchez, Marcel Amill. The landscape of long non-coding RNA expression in the goat brain. Journal of dairy science. 2024-01-26. PMID:38278299. |
the brain regulates multiple metabolic processes, such as food intake, energy expenditure, insulin secretion, hepatic glucose production and glucose/fatty acid metabolism in adipose tissue, which are fundamental for the maintenance of energy and glucose homeostasis during lactation and pregnancy. |
2024-01-26 |
2024-01-29 |
Not clear |
| Kara M Duraccio, Sarah Kamhout, Kelly G Baron, Sirimon Reutrakul, Christopher M Depne. Sleep extension and cardiometabolic health: what it is, possible mechanisms and real-world applications. The Journal of physiology. 2024-01-25. PMID:38268197. |
potential mechanisms underlying this association are complex and multifaceted, including disturbances in circadian timing, food intake and appetitive hormones, brain regions linked to control of hedonic eating, physical activity, an altered microbiome and impaired insulin sensitivity. |
2024-01-25 |
2024-01-27 |
Not clear |
| Takayoshi Sasak. Exploring mechanisms underlying diabetes comorbidities and strategies to prevent vascular complications. Diabetology international. vol 15. issue 1. 2024-01-24. PMID:38264227. |
we have elucidated multifaceted insulin action in various tissues mainly by means of model mice, and it was revealed that insulin regulates endoplasmic reticulum (er) stress response during feeding, whereas er stress 'response failure' contributes to the development of steatohepatitis, one of the major diabetic comorbidities. |
2024-01-24 |
2024-01-26 |
mouse |
| Marta Santos Hernandez, Frank Reimann, Fiona M Gribbl. Cellular mechanisms of incretin hormone secretion. Journal of molecular endocrinology. 2024-01-19. PMID:38240302. |
the incretin hormones glucagon-like peptide-1 (glp-1) and glucose-dependent insulinotropic polypeptide (gip) are involved in the regulation of insulin secretion, appetite, food intake and body weight after their nutrient-induced secretion from the gut. |
2024-01-19 |
2024-01-21 |
Not clear |
| Liping Qiao, Cindy Lu, Tianyi Zang, Brianna Dzyuba, Jianhua Sha. Maternal GLP-1 Receptor Activation Inhibits Fetal Growth. American journal of physiology. Endocrinology and metabolism. 2024-01-10. PMID:38197791. |
glucagon-like peptide 1 (glp-1) regulates food intake, insulin production, and metabolism. |
2024-01-10 |
2024-01-13 |
mouse |
| Carla Wunderle, Franziska Stumpf, Philipp Schuet. Inflammation and response to nutrition interventions. JPEN. Journal of parenteral and enteral nutrition. vol 48. issue 1. 2024-01-09. PMID:38193635. |
inflammation has been identified as a key driver for disease-related malnutrition promoting anorexia, reduced food intake, muscle loss, and on a cellular level, insulin resistance, which together stimulate catabolism. |
2024-01-09 |
2024-01-10 |
Not clear |
| Haiyan Wang, Amy Zheng, Dominic Thorley, Edward Belisario Arias, Gregory D Carte. Independent and combined effects of calorie restriction and AICAR on glucose uptake and insulin signaling in skeletal muscles from 24-month-old female and male rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 2024-01-05. PMID:38181403. |
we assessed the effects of two levels of calorie restriction (cr; eating either 15% or 35% less than ad libitum, al, food intake for 8 weeks) by 24-month-old female and male rats on glucose uptake (gu) and phosphorylation of key signaling proteins (akt; amp-activated protein kinase, ampk; akt substrate of 160 kda, as160) measured in isolated skeletal muscles that underwent four incubation conditions (without either insulin or aicar, an ampk activator; with aicar alone; with insulin alone; or with insulin and aicar). |
2024-01-05 |
2024-01-08 |
rat |
| Takuya Ensho, Jun Hino, Yoko Ueda, Mikiya Miyazato, Hiroshi Iwakur. Vascular endothelial cell-specific overexpression of CNP did not improve liver fibrosis in HFFCD-induced NASH, but did improve renal lesions. Peptides. 2023-12-29. PMID:38157939. |
mice with endothelial-cell-specific overexpression of c-type natriuretic peptide (e-cnp tg mice) were shown to be protected against hepatic fibrosis and inflammation induced by high fat diet (hfd) feeding, with improved insulin sensitivity and attenuated weight gain. |
2023-12-29 |
2024-01-05 |
mouse |
| Myrem Jesame F Sarno, Dan Philip F Hernandez, Melgar O Matula. "Normal but Catastrophic" Euglycemic Diabetic Ketoacidosis Precipitated by Sodium-Glucose Cotransporter-2 Inhibitor Use: A Case Report. Cureus. vol 15. issue 11. 2023-12-25. PMID:38143642. |
eudka is more common in patients with diabetes mellitus on sglt2 inhibitors with lower mass index and decreased glycogen store which can be triggered by surgery, infection, trauma, a major illness or reduced food intake and persistent vomiting, gastroparesis, dehydration, and reduced insulin dosages. |
2023-12-25 |
2023-12-27 |
Not clear |
| Myrem Jesame F Sarno, Dan Philip F Hernandez, Melgar O Matula. "Normal but Catastrophic" Euglycemic Diabetic Ketoacidosis Precipitated by Sodium-Glucose Cotransporter-2 Inhibitor Use: A Case Report. Cureus. vol 15. issue 11. 2023-12-25. PMID:38143642. |
this is a case of a 34-year-old male, filipino, diagnosed with type 2 diabetes mellitus, who was maintained on dapagliflozin + metformin 5mg/1000mg taken twice a day with good compliance and was admitted with eudka precipitated by decreased food intake and managed with intravenous insulin. |
2023-12-25 |
2023-12-27 |
Not clear |
| Marta Pelczyńska, Ewa Miller-Kasprzak, Marcin Piątkowski, Roksana Mazurek, Mateusz Klause, Anna Suchecka, Magdalena Bucoń, Paweł Bogdańsk. The Role of Adipokines and Myokines in the Pathogenesis of Different Obesity Phenotypes-New Perspectives. Antioxidants (Basel, Switzerland). vol 12. issue 12. 2023-12-23. PMID:38136166. |
the primary mechanism underlying the action of nesfatin-1 involves an increase in insulin sensitivity and reduced food intake. |
2023-12-23 |
2023-12-25 |
human |
| Lei Hao, Chih-Yu Chen, Yong-Hui Nie, Kanakaraju Kaliannan, Jing X Kan. Differential Interventional Effects of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on High Fat Diet-Induced Obesity and Hepatic Pathology. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139090. |
to test this hypothesis, we fed c57bl/6j mice with a high-fat diet (hf) for 10 weeks to induce obesity, then divided the obese mice into three groups and continued feeding for another 10 weeks with one of the following three diets: hf, hf+n-6 (substituted half of sfa with n-6 pufas), and hf+n-3 (substituted half of sfa with n-3 pufas), followed by assessment of body weight, fat mass, insulin sensitivity, hepatic pathology, and lipogenesis. |
2023-12-23 |
2023-12-25 |
mouse |
| Ya-Jie Hu, Xu Zhang, Hong-Ming Lv, Yang Liu, Shi-Ze L. Protein O-GlcNAcylation: The sweet hub in liver metabolic flexibility from a (patho)physiological perspective. Liver international : official journal of the International Association for the Study of the Liver. 2023-12-19. PMID:38110988. |
additionally, it explains the underlying nutritional sensitivity of o-glcnacylation and discusses its mechanism of spatiotemporal modulation of insulin signal transduction and liver metabolic homeostasis during the fasting and feeding cycle. |
2023-12-19 |
2023-12-21 |
Not clear |
| Angela McNelly, Anne Langan, Danielle E Bear, Alexandria Page, Tim Martin, Fatima Seidu, Filipa Santos, Kieron Rooney, Kaifeng Liang, Simon J Heales, Tomas Baldwin, Isabelle Alldritt, Hannah Crossland, Philip J Atherton, Daniel Wilkinson, Hugh Montgomery, John Prowle, Rupert Pearse, Simon Eaton, Zudin A Puthuchear. A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed. Nature communications. vol 14. issue 1. 2023-12-15. PMID:38102152. |
patients who received ketogenic feeding had fewer hypoglycaemic events (0.0% vs. 1.6%), required less exogenous international units of insulin (0 (interquartile range 0-16) vs.78 (interquartile range 0-412) but had slightly more daily episodes of diarrhoea (53.5% vs. 42.9%) over the trial period. |
2023-12-15 |
2023-12-18 |
human |
| Claudio Perez-Leighton, Bredford Kerr, Philipp E Scherer, René Baudrand, Víctor Corté. The interplay between leptin, glucocorticoids, and GLP1 regulates food intake and feeding behaviour. Biological reviews of the Cambridge Philosophical Society. 2023-12-10. PMID:38072002. |
glp1 participates in metabolic adaptation to food intake, regulating insulin secretion and satiety by parallel central and peripheral signalling systems. |
2023-12-10 |
2023-12-17 |
Not clear |
| Qianfeng Xiong, Jing Wang, Kewen Huang, Wenbo Li, Lihui Zhan. Potential Role of GLP-1 Based Therapeutics in Coronary Artery Disease. Frontiers in bioscience (Landmark edition). vol 28. issue 11. 2023-12-08. PMID:38062835. |
glucagon-like peptide-1 (glp-1), an incretin hormone primarily secreted by intestinal l cells, regulates glucose metabolism by increasing insulin synthesis and secretion, decreasing plasma glucagon levels, reducing food intake, and slowing gastric emptying. |
2023-12-08 |
2023-12-17 |
Not clear |
| Song-Yang Zhang, Zahra Danaei, Kyla Bruce, Jennifer F M Chiu, Tony K T La. Acute activation of GFRAL in the area postrema contributes to glucose regulation independent of weight. Diabetes. 2023-12-08. PMID:38064571. |
herein, we report that direct acute gdf15 infusion into the area postrema of high fat fed rats increased intravenous glucose tolerance and insulin sensitivity to lower hepatic glucose production independent of changes in food intake, weight, and plasma insulin levels under conscious, unrestrained, and non-stressed conditions. |
2023-12-08 |
2023-12-17 |
rat |