| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W J J Gerrit. Symposium review: Macronutrient metabolism in the growing calf. Journal of dairy science. vol 102. issue 4. 2019-05-07. PMID:30415852. |
insulin sensitivity in calves is quite high at birth, but decreases independent of feeding strategy in early age to very low levels when compared with other species. |
2019-05-07 |
2023-08-13 |
Not clear |
| Louise Lantier, Ashley S Williams, Curtis C Hughey, Deanna P Bracy, Freyja D James, Muhammad A Ansari, David Gius, David H Wasserma. SIRT2 knockout exacerbates insulin resistance in high fat-fed mice. PloS one. vol 13. issue 12. 2019-05-07. PMID:30533032. |
mitochondrial acetylation state and changes in feeding behavior that result in increased body weight correspond to the deleterious effects of sirt2 ko on insulin action. |
2019-05-07 |
2023-08-13 |
mouse |
| Veronica Jimenez, Claudia Jambrina, Estefania Casana, Victor Sacristan, Sergio Muñoz, Sara Darriba, Jordi Rodó, Cristina Mallol, Miquel Garcia, Xavier León, Sara Marcó, Albert Ribera, Ivet Elias, Alba Casellas, Ignasi Grass, Gemma Elias, Tura Ferré, Sandra Motas, Sylvie Franckhauser, Francisca Mulero, Marc Navarro, Virginia Haurigot, Jesus Ruberte, Fatima Bosc. FGF21 gene therapy as treatment for obesity and insulin resistance. EMBO molecular medicine. vol 10. issue 8. 2019-04-26. PMID:29987000. |
treatment of animals under long-term high-fat diet feeding or of ob/ob mice resulted in marked reductions in body weight, adipose tissue hypertrophy and inflammation, hepatic steatosis, inflammation and fibrosis, and insulin resistance for > 1 year. |
2019-04-26 |
2023-08-13 |
mouse |
| Koji Kawabeta, Shizuka Hase-Tamaru, Masahiro Yuasa, Kazuhito Suruga, Michihiro Sugano, Kazunori Kob. Dietary β-Conglycinin Modulates Insulin Sensitivity, Body Fat Mass, and Lipid Metabolism in Obese Otsuka Long-Evans Tokushima Fatty (OLETF) Rats. Journal of oleo science. vol 68. issue 4. 2019-04-24. PMID:30867392. |
since plasma adiponectin is known to affect both lipid and glucose metabolism, feeding a diet containing β-con could modulate insulin sensitivity. |
2019-04-24 |
2023-08-13 |
rat |
| Emma K Lees, Ruth Banks, Chelsea Cook, Sophie Hill, Nicola Morrice, Louise Grant, Nimesh Mody, Mirela Delibegovi. Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice. Scientific reports. vol 7. issue 1. 2019-04-22. PMID:28855637. |
mr and lr decreased body and fat mass, increased food intake, elevated lipid cycling in wat and improved whole-body glucose metabolism and hepatic insulin sensitivity in comparison to the control diet. |
2019-04-22 |
2023-08-13 |
mouse |
| Tyler W Benson, Daniel S Weintraub, Matthew Crowe, Nicole K H Yiew, Orishebawo Popoola, Ajay Pillai, Joel Joseph, Krystal Archer, Charlotte Greenway, Tapan K Chatterjee, James Mintz, David W Stepp, Brian K Stansfield, Weiqin Chen, Julia Brittain, Vladimir Y Bogdanov, Yan Gao, James G Wilson, Yaoliang Tang, Ha Won Kim, Neal L Weintrau. Deletion of the Duffy antigen receptor for chemokines (DARC) promotes insulin resistance and adipose tissue inflammation during high fat feeding. Molecular and cellular endocrinology. vol 473. 2019-04-22. PMID:29341885. |
deletion of the duffy antigen receptor for chemokines (darc) promotes insulin resistance and adipose tissue inflammation during high fat feeding. |
2019-04-22 |
2023-08-13 |
Not clear |
| Hai-Tao Xiao, Bo Wen, Zi-Wan Ning, Li-Xiang Zhai, Cheng-Hui Liao, Cheng-Yuan Lin, Huai-Xue Mu, Zhao-Xiang Bia. Cyclocarya paliurus tea leaves enhances pancreatic β cell preservation through inhibition of apoptosis. Scientific reports. vol 7. issue 1. 2019-04-18. PMID:28831132. |
here, we demonstrate that the extract of c. paliurus leaves significantly decreased body loss, food intake and blood glucose level, and increased blood insulin level, β-cell number and insulin-producing β cells in high-fat diet-low dose stz-induced diabetic mice. |
2019-04-18 |
2023-08-13 |
mouse |
| Nicole E Cummings, Elizabeth M Williams, Ildiko Kasza, Elizabeth N Konon, Michael D Schaid, Brian A Schmidt, Chetan Poudel, Dawn S Sherman, Deyang Yu, Sebastian I Arriola Apelo, Sara E Cottrell, Gabriella Geiger, Macy E Barnes, Jaclyn A Wisinski, Rachel J Fenske, Kristina A Matkowskyj, Michelle E Kimple, Caroline M Alexander, Matthew J Merrins, Dudley W Lammin. Restoration of metabolic health by decreased consumption of branched-chain amino acids. The Journal of physiology. vol 596. issue 4. 2019-04-16. PMID:29266268. |
we recently found that feeding healthy mice a diet with reduced levels of branched-chain amino acids (bcaas), which are associated with insulin resistance in both humans and rodents, modestly improves glucose tolerance and slows fat mass gain. |
2019-04-16 |
2023-08-13 |
mouse |
| Leesun Ryu, YongJin Cheon, Yang Hoon Huh, Seondong Pyo, Satya Chinta, Hongsoo Choi, Rebecca A Butcher, Kyuhyung Ki. Feeding state regulates pheromone-mediated avoidance behavior via the insulin signaling pathway in The EMBO journal. vol 37. issue 15. 2019-04-16. PMID:29925517. |
feeding state regulates pheromone-mediated avoidance behavior via the insulin signaling pathway in animals change sensory responses and their eventual behaviors, depending on their internal metabolic status and external food availability. |
2019-04-16 |
2023-08-13 |
Not clear |
| Carlos Kiyoshi Katashima, Vagner Ramon Rodrigues Silva, Luciene Lenhare, Rodrigo Miguel Marin, José Barreto Campello Carvalheir. iNOS promotes hypothalamic insulin resistance associated with deregulation of energy balance and obesity in rodents. Scientific reports. vol 7. issue 1. 2019-04-11. PMID:28835706. |
herein, we demonstrated that the intracerebroventricular infusion of the nitric oxide (no) donor s-nitrosoglutathione (gsno) promoted hypothalamic insulin signaling resistance and replicated the food intake pattern of obese individuals. |
2019-04-11 |
2023-08-13 |
Not clear |
| Ya-Feng Zhou, Xiao-Ming Ying, Xiao-Fen He, Sheng-Yun Shou, Jun-Jun Wei, Zhao-Xia Tai, Xiao-Mei Shao, Yi Liang, Fang Fang, Jian-Qiao Fang, Yong-Liang Jian. Suppressing PKC-dependent membrane P2X3 receptor upregulation in dorsal root ganglia mediated electroacupuncture analgesia in rat painful diabetic neuropathy. Purinergic signalling. vol 14. issue 4. 2019-04-09. PMID:30084084. |
a 7-week feeding of high-fat and high-sugar diet plus a single injection of streptozotocin (stz) in a dose of 35 mg/kg after a 5-week feeding of the diet successfully induced type 2 pdn in rats as revealed by the elevated body weight, fasting blood glucose, fasting insulin and insulin resistance, and the reduced paw withdrawal threshold (pwt), as well as the destructive ultrastructural change of sciatic nerve. |
2019-04-09 |
2023-08-13 |
human |
| Anders M Nää. miR-33: A Metabolic Conundrum. Trends in endocrinology and metabolism: TEM. vol 29. issue 10. 2019-04-08. PMID:29692333. |
showed that mir-33 knockout (ko) mice exhibit obesity, insulin resistance, and increased food intake, suggesting that metabolic regulation by mir-33 is more complex than was previously known. |
2019-04-08 |
2023-08-13 |
mouse |
| Á Kenéz, C Koch, M Korst, J Kesser, K Eder, H Sauerwein, K Hube. Different milk feeding intensities during the first 4 weeks of rearing dairy calves: Part 3: Plasma metabolomics analysis reveals long-term metabolic imprinting in Holstein heifers. Journal of dairy science. vol 101. issue 9. 2019-04-08. PMID:29935828. |
furthermore, plasma sphingomyelin concentrations were affected by ad libitum versus restricted milk replacer feeding, which can imply long-term modulatory mechanisms affecting insulin sensitivity. |
2019-04-08 |
2023-08-13 |
Not clear |
| Chao Chen, Hong-Cai Wang, Xu Zhai, Feng Huang, Dong Wu, Pei-Jing Ron. [Progress of Research on Mechanism of Acupuncture for Diabetes Mellitus]. Zhen ci yan jiu = Acupuncture research. vol 43. issue 9. 2019-04-08. PMID:30232872. |
results showed that acupuncture intervention can relieve dm by 1) reducing body weight through up-regulating leptin level, suppressing insulin resistance and appetite to reduce food intake possibly by way of down-regulating expression of neuropeptide y in the hypothalamus, retarding gastric emptying velocity, increasing small intestinal peristalsis, raising plasma levels of glucagon-like peptide-1 (glp-1) and peptide yy, etc. |
2019-04-08 |
2023-08-13 |
Not clear |
| Chang-Jiang Yu, Qiu-Shi Wang, Ming-Ming Wu, Bin-Lin Song, Chen Liang, Jie Lou, Liang-Liang Tang, Xiao-Di Yu, Na Niu, Xu Yang, Bao-Long Zhang, Yao Qu, Yang Liu, Zhi-Chao Dong, Zhi-Ren Zhan. TRUSS Exacerbates NAFLD Development by Promoting IκBα Degradation in Mice. Hepatology (Baltimore, Md.). vol 68. issue 5. 2019-03-27. PMID:29704259. |
conditional knockout of truss in hepatocytes significantly ameliorated hepatic steatosis, insulin resistance, glucose intolerance, and inflammatory responses in mice after hfd challenge or in spontaneous obese mice with normal chow feeding. |
2019-03-27 |
2023-08-13 |
mouse |
| Huimin Yan, Joseph R Pierce, Kimberly B Myers, Katrina D Dubose, Gabriel S Dubis, Charles J Tanner, Robert C Hickne. Exercise Effects on Adipose Tissue Postprandial Lipolysis and Blood Flow in Children. Medicine and science in sports and exercise. vol 50. issue 6. 2019-03-26. PMID:29381651. |
exercise may be used to normalize lipolytic responses to food intake by increasing insulin sensitivity. |
2019-03-26 |
2023-08-13 |
Not clear |
| Eman F Khaleel, Ghada A Abdel-Alee. Obestatin protects and reverses nonalcoholic fatty liver disease and its associated insulin resistance in rats via inhibition of food intake, enhancing hepatic adiponectin signaling, and blocking ghrelin acylation. Archives of physiology and biochemistry. vol 125. issue 1. 2019-03-25. PMID:29429367. |
obestatin protects and reverses nonalcoholic fatty liver disease and its associated insulin resistance in rats via inhibition of food intake, enhancing hepatic adiponectin signaling, and blocking ghrelin acylation. |
2019-03-25 |
2023-08-13 |
rat |
| Jia Ying Cheang, Peter M Moyl. Glucagon-Like Peptide-1 (GLP-1)-Based Therapeutics: Current Status and Future Opportunities beyond Type 2 Diabetes. ChemMedChem. vol 13. issue 7. 2019-03-18. PMID:29430842. |
glucagon-like peptide-1 (glp-1) is secreted by intestinal l-cells following food intake, and plays an important role in glucose homeostasis due to its stimulation of glucose-dependent insulin secretion. |
2019-03-18 |
2023-08-13 |
Not clear |
| Saeid Bahremand, Hoo Sang Ko, Ramin Balouchzadeh, H Felix Lee, Sarah Park, Guim Kwo. Neural network-based model predictive control for type 1 diabetic rats on artificial pancreas system. Medical & biological engineering & computing. vol 57. issue 1. 2019-03-18. PMID:30069675. |
first, we developed a mathematical model for diabetic rats, which was used to identify individual virtual subjects by fitting to empirical data collected through an aps, including bgl data, insulin injection, and food intake. |
2019-03-18 |
2023-08-13 |
human |
| W A Banks, S A Farr, T S Salameh, M L Niehoff, E M Rhea, J E Morley, A J Hanson, K M Hansen, S Craf. Triglycerides cross the blood-brain barrier and induce central leptin and insulin receptor resistance. International journal of obesity (2005). vol 42. issue 3. 2019-03-15. PMID:28990588. |
resistance at the brain receptors for leptin and insulin has been associated with increased feeding, obesity and cognitive impairments. |
2019-03-15 |
2023-08-13 |
Not clear |