| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lewin Small, Amanda E Brandon, Lake-Ee Quek, James R Krycer, David E James, Nigel Turner, Gregory J Coone. Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake. American journal of physiology. Endocrinology and metabolism. vol 315. issue 2. 2019-07-09. PMID:29406780. |
we have investigated whether acute activation of pdh in muscle can alleviate the insulin resistance caused by feeding animals a high-fat diet (hfd). |
2019-07-09 |
2023-08-13 |
rat |
| Jesús E Villanueva, Christopher Livelo, Adriana S Trujillo, Sahaana Chandran, Brendon Woodworth, Leo Andrade, Hiep D Le, Uri Manor, Satchidananda Panda, Girish C Melkan. Time-restricted feeding restores muscle function in Drosophila models of obesity and circadian-rhythm disruption. Nature communications. vol 10. issue 1. 2019-07-09. PMID:31221967. |
imposing time-restricted feeding (trf) paradigm in which flies were fed for 12 h during the day counteracts obesity-induced dysmetabolism and improves muscle performance by suppressing intramuscular fat deposits, phospho-akt level, mitochondrial aberrations, and markers of insulin resistance. |
2019-07-09 |
2023-08-13 |
human |
| R C Laker, C Garde, D M Camera, W J Smiles, J R Zierath, J A Hawley, R Barrè. Transcriptomic and epigenetic responses to short-term nutrient-exercise stress in humans. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29123172. |
high fat feeding impairs skeletal muscle metabolic flexibility and induces insulin resistance, whereas exercise training exerts positive effects on substrate handling and improves insulin sensitivity. |
2019-07-08 |
2023-08-13 |
human |
| Pedro Reyes-Castillo, Raquel González-Vázquez, Angélica Gutiérrez-Nava, Felipe Mendoza-Pérez, María Del Carmen Navarro González, Alfonso Salgado-Sguayo, Edgard Torres-Maravilla, Lino Mayorga Reyes, Alejandro Azaola-Espinos. Anthropometric measure and adipokine levels of a young undergraduate population with a usual diet. Nutricion hospitalaria. vol 36. issue 1. 2019-07-05. PMID:30836761. |
due to the inclusion criteria and their own decision of participating, 90 attended the anthropometric, health indicators: waist circumference (wc), waist to hip ratio (whr), waist to height ratio (whtr), and homeostatic model assessment-insulin resistance index (homa-ir) studies and completed the questionnaire of frequency of food intake; and 34 participants were selected to perform the determination of biochemical parameters, insulin and adipokines levels: leptin, il-6, il-8, tumor necrosis factor alpha (tnf-α), monocyte chemoattractant protein-1 (mcp-1) and hepatocyte growth factor (hgf). |
2019-07-05 |
2023-08-13 |
human |
| Hiraku On. Molecular Mechanisms of Hypothalamic Insulin Resistance. International journal of molecular sciences. vol 20. issue 6. 2019-07-03. PMID:30875909. |
insulin exists in the central nervous system, where it executes two important functions in the hypothalamus: the suppression of food intake and the improvement of glucose metabolism. |
2019-07-03 |
2023-08-13 |
Not clear |
| D P Laureano, M B Alves, P M Miguel, T D Machado, A R Reis, A B Mucellini, F S Cunha, C Lampert, A P A Salvador, R Dalle Molle, P R Mosca, I Pokhvisneva, M Desai, M G Ross, P P Silveir. Intrauterine Growth Restriction Modifies the Accumbal Dopaminergic Response to Palatable Food Intake. Neuroscience. vol 400. 2019-06-21. PMID:30599270. |
we measured the release of dopamine in the accumbens during palatable food intake in iugr rats both at baseline and in response to insulin. |
2019-06-21 |
2023-08-13 |
rat |
| Y Inabu, J Pyo, S Pletts, L L Guan, M A Steele, T Sugin. Effect of extended colostrum feeding on plasma glucagon-like peptide-1 concentration in newborn calves. Journal of dairy science. vol 102. issue 5. 2019-06-14. PMID:30827561. |
blood samples were obtained before (1 and 2 h after birth) and after (until 72 h after birth; 42 time points) the first colostrum feeding, and plasma concentrations of glucose, insulin, and glp-1 were measured. |
2019-06-14 |
2023-08-13 |
Not clear |
| Y Inabu, J Pyo, S Pletts, L L Guan, M A Steele, T Sugin. Effect of extended colostrum feeding on plasma glucagon-like peptide-1 concentration in newborn calves. Journal of dairy science. vol 102. issue 5. 2019-06-14. PMID:30827561. |
postprandial plasma concentration of glucose was not correlated with that of glp-1 but was positively correlated with that of insulin for the 4-h period after feeding on d 1 (r = 0.30) and d 3 after birth (r = 0.33). |
2019-06-14 |
2023-08-13 |
Not clear |
| Y Inabu, J Pyo, S Pletts, L L Guan, M A Steele, T Sugin. Effect of extended colostrum feeding on plasma glucagon-like peptide-1 concentration in newborn calves. Journal of dairy science. vol 102. issue 5. 2019-06-14. PMID:30827561. |
postprandial plasma concentration of glp-1 was positively correlated with that of insulin for the 4-h period after feeding on d 3 after birth (r = 0.20). |
2019-06-14 |
2023-08-13 |
Not clear |
| Y Inabu, J Pyo, S Pletts, L L Guan, M A Steele, T Sugin. Effect of extended colostrum feeding on plasma glucagon-like peptide-1 concentration in newborn calves. Journal of dairy science. vol 102. issue 5. 2019-06-14. PMID:30827561. |
these results indicate that extended colostrum feeding may increase plasma glp-1 concentrations, especially 3 d after birth, but further study is necessary to determine the effect on plasma insulin and glucose concentrations. |
2019-06-14 |
2023-08-13 |
Not clear |
| K V Derkach, I B Sukhov, V M Bondareva, A O Shpako. [The effect of Metformin on metabolic parameters and hypothalamic signaling systems in rats with obesity induced by a high-carbohydrate/high-fat diet.] Advances in gerontology = Uspekhi gerontologii. vol 31. issue 1. 2019-06-11. PMID:29860743. |
thus, mf treatment changes functional activity of the hypothalamic melanocortin, dopamine and serotonin systems in obese rats, which is one of the reasons to decrease their food intake and to restore the metabolic indicators and insulin sensitivity. |
2019-06-11 |
2023-08-13 |
rat |
| Carolyn M Slupsky, Xuan He, Olle Hernell, Yvonne Andersson, Colin Rudolph, Bo Lönnerdal, Christina E Wes. Postprandial metabolic response of breast-fed infants and infants fed lactose-free vs regular infant formula: A randomized controlled trial. Scientific reports. vol 7. issue 1. 2019-06-10. PMID:28623320. |
plasma metabolites and insulin were measured at baseline, 15, 30, 60, 90 and 120 min after feeding. |
2019-06-10 |
2023-08-13 |
Not clear |
| Surendra K Shukla, Aneesha Dasgupta, Scott E Mulder, Pankaj K Sing. Molecular and Physiological Evaluation of Pancreatic Cancer-Induced Cachexia. Methods in molecular biology (Clifton, N.J.). vol 1882. 2019-06-06. PMID:30378066. |
next, we have detailed the orthotopic implantation mouse models of pancreatic cancer and evaluation of different physiological parameters, including body weight, food intake, body composition analysis, glucose tolerance test, insulin resistance test, grip strength measurement, and rotarod performance test. |
2019-06-06 |
2023-08-13 |
mouse |
| Xue-Jing Liu, Na-Na Duan, Chang Liu, Chen Niu, Xiu-Ping Liu, Jian W. Characterization of a murine nonalcoholic steatohepatitis model induced by high fat high calorie diet plus fructose and glucose in drinking water. Laboratory investigation; a journal of technical methods and pathology. vol 98. issue 9. 2019-05-28. PMID:29959418. |
in contrast, hfcd-hf/g feeding resulted in a remarkable increase in body weight, subcutaneous and visceral adipose tissue, macrosteatosis with a nearly seven-fold increase in triglyceride and ffa content, accompanied with marked hepatocellular injury, inflammatory responses, fibrosis, and insulin resistance, and represented as typical nash in histopathology, metabolic, and adipokine profiles in a progressive manner. |
2019-05-28 |
2023-08-13 |
mouse |
| Xue-Jing Liu, Na-Na Duan, Chang Liu, Chen Niu, Xiu-Ping Liu, Jian W. Characterization of a murine nonalcoholic steatohepatitis model induced by high fat high calorie diet plus fructose and glucose in drinking water. Laboratory investigation; a journal of technical methods and pathology. vol 98. issue 9. 2019-05-28. PMID:29959418. |
in conclusion, feeding hfcd-hf/g resulted in a reliable nash model in mice with remarkable necroptosis, steatosis, fibrosis, and insulin resistance as well as a disordered profile of lipid metabolism and adipokine, and hfcd caused significant nash features in histopathology and metabolic profiles only at a late stage. |
2019-05-28 |
2023-08-13 |
mouse |
| Nathan L Price, Abhishek K Singh, Noemi Rotllan, Leigh Goedeke, Allison Wing, Alberto Canfrán-Duque, Alberto Diaz-Ruiz, Elisa Araldi, Ángel Baldán, Joao-Paulo Camporez, Yajaira Suárez, Matthew S Rodeheffer, Gerald I Shulman, Rafael de Cabo, Carlos Fernández-Hernand. Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance. Cell reports. vol 22. issue 8. 2019-05-27. PMID:29466739. |
genetic ablation of mir-33 increases food intake, enhances adipose tissue expansion, and promotes obesity and insulin resistance. |
2019-05-27 |
2023-08-13 |
Not clear |
| Florian Kahles, Ana Liberman, Constantin Halim, Matthias Rau, Julia Möllmann, Robert Werner Mertens, Marcia Rückbeil, Irmgard Diepolder, Benedikt Walla, Sebastian Diebold, Mathias Burgmaier, Corinna Lebherz, Nikolaus Marx, Michael Lehrk. The incretin hormone GIP is upregulated in patients with atherosclerosis and stabilizes plaques in ApoE Molecular metabolism. vol 14. 2019-05-27. PMID:29884547. |
the incretin hormone gip is upregulated in patients with atherosclerosis and stabilizes plaques in apoe the incretin hormones glp-1 (glucagon-like peptide-1) and gip (glucose-dependent insulinotropic peptide) are secreted by the gut after food intake leading to pancreatic insulin secretion and glucose lowering. |
2019-05-27 |
2023-08-13 |
mouse |
| Laura N Castellani, Jennifer Wilkin, Andrew R Abela, Louise Benarroch, Zohra Ahasan, Celine Teo, Virginia Wilson, Chantel Kowalchuk, Adria Giacca, Gary J Remington, Margaret K Hah. Effects of acute olanzapine exposure on central insulin-mediated regulation of whole body fuel selection and feeding. Psychoneuroendocrinology. vol 98. 2019-05-08. PMID:30142549. |
here we investigated whether olanzapine treatment might also affect the ability of central insulin treatment to regulate food intake and fuel preference in the light and dark cycle. |
2019-05-08 |
2023-08-13 |
rat |
| Laura N Castellani, Jennifer Wilkin, Andrew R Abela, Louise Benarroch, Zohra Ahasan, Celine Teo, Virginia Wilson, Chantel Kowalchuk, Adria Giacca, Gary J Remington, Margaret K Hah. Effects of acute olanzapine exposure on central insulin-mediated regulation of whole body fuel selection and feeding. Psychoneuroendocrinology. vol 98. 2019-05-08. PMID:30142549. |
the reduction in rer during the dark phase was mirrored by decreased food intake with icv insulin, but not olanzapine treated rats. |
2019-05-08 |
2023-08-13 |
rat |
| Laura N Castellani, Jennifer Wilkin, Andrew R Abela, Louise Benarroch, Zohra Ahasan, Celine Teo, Virginia Wilson, Chantel Kowalchuk, Adria Giacca, Gary J Remington, Margaret K Hah. Effects of acute olanzapine exposure on central insulin-mediated regulation of whole body fuel selection and feeding. Psychoneuroendocrinology. vol 98. 2019-05-08. PMID:30142549. |
the reduction in food intake by icv-insulin was abolished in rats co-administered olanzapine suggesting rapid induction of central insulin resistance. |
2019-05-08 |
2023-08-13 |
rat |