| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishal Kothari, Yuwen Luo, Talia Tornabene, Ann Marie O'Neill, Michael W Greene, Thangiah Geetha, Jeganathan Ramesh Bab. High fat diet induces brain insulin resistance and cognitive impairment in mice. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 2. 2018-12-11. PMID:27771511. |
metabolic phenotypes were characterized for energy expenditure, physical activity, and food intake, and glucose and insulin tolerance tests. |
2018-12-11 |
2023-08-13 |
mouse |
| Lena J Tiedemann, Sebastian M Schmid, Judith Hettel, Katrin Giesen, Paul Francke, Christian Büchel, Stefanie Brasse. Central insulin modulates food valuation via mesolimbic pathways. Nature communications. vol 8. 2018-12-11. PMID:28719580. |
these data demonstrate how central insulin modulates the cross-talk between homeostatic and non-homeostatic feeding systems, suggesting that dysfunctions of these neural interactions may promote metabolic disorders. |
2018-12-11 |
2023-08-13 |
human |
| Flávia de T Frias, Karina C E Rocha, Mariana de Mendonça, Gilson M Murata, Hygor N Araujo, Luís G O de Sousa, Érica de Sousa, Sandro M Hirabara, Nayara de C Leite, Everardo M Carneiro, Rui Curi, Leonardo R Silveira, Alice C Rodrigue. Fenofibrate reverses changes induced by high-fat diet on metabolism in mice muscle and visceral adipocytes. Journal of cellular physiology. vol 233. issue 4. 2018-12-11. PMID:28926107. |
in dio mice, fenofibrate prevented weight gain induced by hfd feeding by increasing energy expenditure; improved whole body glucose homeostasis, and in skeletal muscle, increased insulin dependent glucose uptake, mir-1a levels, reduced intramuscular lipid accumulation, and phospho-ampkα2 levels. |
2018-12-11 |
2023-08-13 |
mouse |
| M Raja Gopal Reddy, S Mullapudi Venkata, U K Putcha, S M Jeyakuma. Vitamin A deficiency induces endoplasmic reticulum stress and apoptosis in pancreatic islet cells: Implications of stearoyl-CoA desaturase 1-mediated oleic acid synthesis. Experimental cell research. vol 364. issue 1. 2018-12-11. PMID:29409806. |
compared to the control, feeding of vad diet (alone or with hfr) resulted in pancreatic intra-islet vessel dilation and reduced plasma insulin, glucagon and c-peptide levels, however, glucose levels decreased only in vadhfr group. |
2018-12-11 |
2023-08-13 |
rat |
| Helen J Dranse, T M Zaved Waise, Sophie C Hamr, Paige V Bauer, Mona A Abraham, Brittany A Rasmussen, Tony K T La. Physiological and therapeutic regulation of glucose homeostasis by upper small intestinal PepT1-mediated protein sensing. Nature communications. vol 9. issue 1. 2018-12-11. PMID:29549253. |
here we show that acute administration of casein hydrolysate directly into the upper small intestine increases glucose tolerance and inhibits glucose production in rats, independently of changes in plasma amino acids, insulin levels, and food intake. |
2018-12-11 |
2023-08-13 |
rat |
| Ralf Elvert, Andreas W Herling, Martin Bossart, Tilo Weiss, Baohong Zhang, Pierre Wenski, Jörn Wandschneider, Sabrina Kleutsch, Uwe Butty, Aimo Kannt, Michael Wagner, Torsten Haack, Andreas Evers, Angela Dudda, Martin Lorenz, Stefanie Keil, Philip J Larse. Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates. Diabetes, obesity & metabolism. vol 20. issue 8. 2018-12-11. PMID:29938884. |
we performed acute and chronic studies in healthy and diet-induced obese animals using mouse-specific or monkey-specific dual glp-1r/gcgr agonists to investigate their effects on food intake, body weight, blood glucose control and insulin secretion. |
2018-12-11 |
2023-08-13 |
mouse |
| Pan Zhuang, Qiyang Shou, Yanhua Lu, Guangfa Wang, Jieni Qiu, Jun Wang, Lilin He, Jingnan Chen, Jingjing Jiao, Yu Zhan. Arachidonic acid sex-dependently affects obesity through linking gut microbiota-driven inflammation to hypothalamus-adipose-liver axis. Biochimica et biophysica acta. Molecular basis of disease. vol 1863. issue 11. 2018-11-26. PMID:28711599. |
systemic adiposity and inflammation, metabolic profiles, gut microbiota composition, short-chain fatty acids production, hypothalamic feeding regulators, browning process of adipocytes, hepatosteatosis, and insulin resistance in adipose were investigated. |
2018-11-26 |
2023-08-13 |
mouse |
| Patrick M Solverson, William V Rumpler, Jayme L Leger, Benjamin W Redan, Mario G Ferruzzi, David J Baer, Thomas W Castonguay, Janet A Novotn. Blackberry Feeding Increases Fat Oxidation and Improves Insulin Sensitivity in Overweight and Obese Males. Nutrients. vol 10. issue 8. 2018-11-26. PMID:30096878. |
blackberry feeding increases fat oxidation and improves insulin sensitivity in overweight and obese males. |
2018-11-26 |
2023-08-13 |
human |
| Jinghan Sun, Chang Liu, Xiaobing Bai, Xiaoting Li, Jingyun Li, Zhiping Zhang, Yunpeng Zhang, Jing Guo, Yan L. Drosophila FIT is a protein-specific satiety hormone essential for feeding control. Nature communications. vol 8. 2018-11-19. PMID:28102207. |
interestingly, fit is a sexually dimorphic gene, and consequently protein consumption-induced insulin release, as well as protein feeding behaviour, are also dimorphic between sexes. |
2018-11-19 |
2023-08-13 |
drosophila_melanogaster |
| P Larraufie, C Martin-Gallausiaux, N Lapaque, J Dore, F M Gribble, F Reimann, H M Blottier. SCFAs strongly stimulate PYY production in human enteroendocrine cells. Scientific reports. vol 8. issue 1. 2018-11-16. PMID:29311617. |
peptide-yy (pyy) and glucagon-like peptide-1 (glp-1) play important roles in the regulation of food intake and insulin secretion, and are of translational interest in the field of obesity and diabetes. |
2018-11-16 |
2023-08-13 |
mouse |
| Rosane Gomez, Greice Caletti, Bruno Dutra Arbo, Ana Lúcia Hoefel, Ricardo Schneider, Alana Witt Hansen, Rianne Remus Pulcinelli, Luana Freese, Solange Bandiera, Luiz Carlos Kucharski, Helena Maria Tanhauser Barro. Acute intraperitoneal administration of taurine decreases the glycemia and reduces food intake in type 1 diabetic rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 103. 2018-11-13. PMID:29710660. |
parameters such as palatable food intake, gastrointestinal transit rate, serum glucose, insulin, leptin, and glucagon levels were measured 60 min after the last taurine administration. |
2018-11-13 |
2023-08-13 |
mouse |
| Alisha V Ling, Mary E Gearing, Ivana Semova, Dong-Ju Shin, Rebecca Clements, Zon W Lai, Sudha B Biddinge. FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice. Endocrinology. vol 159. issue 3. 2018-11-05. PMID:29300910. |
insulin coordinates the complex response to feeding, affecting numerous metabolic and hormonal pathways. |
2018-11-05 |
2023-08-13 |
mouse |
| Paulo Matafome, Hans Eickhoff, Liliana Letra, Raquel Seiç. Neuroendocrinology of Adipose Tissue and Gut-Brain Axis. Advances in neurobiology. vol 19. 2018-11-01. PMID:28933061. |
in addition, insulin and leptin derived from adipose tissue are involved in long-acting adiposity signals and regulate body weigh as well as the amount of energy stored as fat over time.this chapter focuses on the gastrointestinal-, pancreatic-, and adipose tissue-derived signals which are integrated in selective orexigenic and anorexigenic brain areas that, in turn, regulate food intake, energy expenditure, and peripheral metabolism. |
2018-11-01 |
2023-08-13 |
Not clear |
| Roshni Patel, Gaurang Sha. High-fat diet exposure from pre-pubertal age induces polycystic ovary syndrome (PCOS) in rats. Reproduction (Cambridge, England). vol 155. issue 2. 2018-10-31. PMID:29196492. |
feeding of hfd gradually increase glucose intolerance and fasting insulin levels. |
2018-10-31 |
2023-08-13 |
rat |
| Wen-Ya Huang, Xin Zou, Fu-Er Lu, Hao Su, Chu Zhang, Yan-Lin Ren, Ke Fang, Li-Jun Xu, Kai-Fu Wang, Qing-Jie Chen, Hui Don. Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats. Current medical science. vol 38. issue 4. 2018-10-31. PMID:30128882. |
the amount of food intake and metabolic parameters such as body weight increase rate, fasting plasma glucose (fpg), fasting insulin (fins), homeostasis model assessment-insulin resistance (homa-ir) and plasma inflammatory markers were measured. |
2018-10-31 |
2023-08-13 |
rat |
| Wen-Ya Huang, Xin Zou, Fu-Er Lu, Hao Su, Chu Zhang, Yan-Lin Ren, Ke Fang, Li-Jun Xu, Kai-Fu Wang, Qing-Jie Chen, Hui Don. Jiao-tai-wan Up-regulates Hypothalamic and Peripheral Circadian Clock Gene Cryptochrome and Activates PI3K/AKT Signaling in Partially Sleep-deprived Rats. Current medical science. vol 38. issue 4. 2018-10-31. PMID:30128882. |
jtw significantly decreased the body weight increase rate and food intake, ameliorated systemic inflammation and insulin resistance. |
2018-10-31 |
2023-08-13 |
rat |
| Babu Nageswararao Kanuri, Jitendra S Kanshana, Sanjay C Rebello, Priya Pathak, Anand P Gupta, Jiaur R Gayen, Kumaravelu Jagavelu, Madhu Dikshi. Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance. Scientific reports. vol 7. 2018-10-29. PMID:28106120. |
the present study aimed to assess ir in inos ko mice after 5 weeks of lfd feeding by monitoring body composition, energy homeostasis, insulin sensitivity/signaling, nitrite content and gene expressions changes in the tissues. |
2018-10-29 |
2023-08-13 |
mouse |
| V A Matheus, Lcs Monteiro, R B Oliveira, D A Maschio, C B Collares-Buzat. Butyrate reduces high-fat diet-induced metabolic alterations, hepatic steatosis and pancreatic beta cell and intestinal barrier dysfunctions in prediabetic mice. Experimental biology and medicine (Maywood, N.J.). vol 242. issue 12. 2018-10-24. PMID:28504618. |
significantly reduced the weight gain and body adiposity as well as the insulin resistant state, hyperglycemia and hyperinsulinemia, without changing food intake. |
2018-10-24 |
2023-08-13 |
mouse |
| Lena Golick, Youngah Han, Yoo Kim, Sang Won Par. BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β. Cellular and molecular life sciences : CMLS. vol 75. issue 10. 2018-10-24. PMID:29127434. |
here, we show that brd7 increases phosphorylation of glycogen synthase kinase 3β (gsk3β) in response to activation of the insulin receptor-signaling pathway shortly after insulin stimulation and the nutrient-sensing pathway after feeding. |
2018-10-24 |
2023-08-13 |
Not clear |
| Shanshan Wu, Kai Dong, Jiajia Wang, Yaxin B. Tumor necrosis factor alpha improves glucose homeostasis in diabetic mice independent with tumor necrosis factor receptor 1 and tumor necrosis factor receptor 2. Endocrine journal. vol 65. issue 6. 2018-10-24. PMID:29576600. |
after high fat diet (hfd) feeding, we detected that the insulin resistance was dramatically improved and circulated tnf-α was upregulated in tnfr1/r2 dko mice. |
2018-10-24 |
2023-08-13 |
mouse |