| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Willian O Dos Santos, Daniela O Gusmao, Frederick Wasinski, Edward O List, John J Kopchick, Jose Donat. Effects of Growth Hormone Receptor Ablation in Corticotropin-Releasing Hormone Cells. International journal of molecular sciences. vol 22. issue 18. 2021-10-22. PMID:34576072. |
ghr ablation in crh cells did not cause significant changes in body weight, body composition, food intake, substrate oxidation, locomotor activity, glucose tolerance, insulin sensitivity, counterregulatory response to 2-deoxy-d-glucose and ghrelin-induced food intake. |
2021-10-22 |
2023-08-13 |
mouse |
| Lara R Nyman, Liqun Tian, Doug A Hamm, Trenton R Schoeb, Barbara A Gower, Tim R Nagy, Philip A Woo. Long term effects of high fat or high carbohydrate diets on glucose tolerance in mice with heterozygous carnitine palmitoyltransferase-1a (CPT-1a) deficiency: Diet influences on CPT1a deficient mice. Nutrition & diabetes. vol 1. 2021-10-21. PMID:22229081. |
conclusions: cpt-1a deficiency preserved insulin sensitivity when challenged by long term feeding of either diet. |
2021-10-21 |
2023-08-12 |
mouse |
| X Charlie Don. Sirtuin biology and relevance to diabetes treatment. Diabetes management (London, England). vol 2. issue 3. 2021-10-21. PMID:23024708. |
sirt1 regulates glucose and lipid homeostasis in the liver, modulates insulin secretion in pancreatic islets, controls insulin sensitivity and glucose uptake in skeletal muscle, increases adiponectin expression in white adipose tissue and controls food intake and energy expenditure in the brain. |
2021-10-21 |
2023-08-12 |
mouse |
| Chang Hwa Jung, Jiyun Ahn, Tae-Il Jeon, Tae Wan Kim, Tae Youl H. Syzygium aromaticum ethanol extract reduces high-fat diet-induced obesity in mice through downregulation of adipogenic and lipogenic gene expression. Experimental and therapeutic medicine. vol 4. issue 3. 2021-10-21. PMID:23181109. |
after 9 weeks of feeding, the body weight; white adipose tissue (wat) mass; serum triglyceride (tg), total cholesterol (tc), high-density lipoprotein (hdl) cholesterol, glucose, insulin and leptin; hepatic lipid accumulation; and levels of lipid metabolism-related genes in the liver and wat were measured. |
2021-10-21 |
2023-08-12 |
mouse |
| Xu Sun, Maomin Song, Rixing Bai, Shi Cheng, Ying Xing, Huisheng Yuan, Pilin Wang, Lisa Zho. Ileal interposition surgery-induced improvement of hyperglycemia and insulin resistance in Goto-Kakizaki rats by upregulation of TCF7L2 expression. Experimental and therapeutic medicine. vol 5. issue 5. 2021-10-21. PMID:23737909. |
fasting plasma glucose, body weight, food intake per 1 kg body weight, insulin and a homeostasis model assessment of insulin resistance (homa-ir) were measured pre- and post-surgery. |
2021-10-21 |
2023-08-12 |
rat |
| Susana R Patton, Mark A Clement. Continuous Glucose Monitoring Versus Self-monitoring of Blood Glucose in Children with Type 1 Diabetes- Are there Pros and Cons for Both? US endocrinology. vol 8. issue 1. 2021-10-21. PMID:24312136. |
monitoring provides the data necessary for patients to make daily management decisions related to food intake, insulin dose, and physical exercise and can enable patients to avoid potentially dangerous episodes of hypo- and hyperglycemia. |
2021-10-21 |
2023-08-12 |
Not clear |
| b' Camila Cremonezi Japur, Rosa Wanda Diez-Garcia, Fernanda Rodrigues de Oliveira Penaforte, Marcos Felipe Silva de S\\xc3\\xa. Imbalance Between Postprandial Ghrelin and Insulin Responses to an Ad Libitum Meal in Obese Women With Polycystic Ovary Syndrome. Reproductive sciences (Thousand Oaks, Calif.). vol 21. issue 8. 2021-10-21. PMID:24520086.' |
obese women with polycystic ovary syndrome (pcos) may have impairment in the regulation of food intake associated with ghrelin and insulin. |
2021-10-21 |
2023-08-12 |
Not clear |
| b' Camila Cremonezi Japur, Rosa Wanda Diez-Garcia, Fernanda Rodrigues de Oliveira Penaforte, Marcos Felipe Silva de S\\xc3\\xa. Imbalance Between Postprandial Ghrelin and Insulin Responses to an Ad Libitum Meal in Obese Women With Polycystic Ovary Syndrome. Reproductive sciences (Thousand Oaks, Calif.). vol 21. issue 8. 2021-10-21. PMID:24520086.' |
the imbalance in the feedback mechanisms between insulin and ghrelin, present in obese women, especially those with ir, may affect food intake throughout the day and that could be a mechanism for the development of obesity in pcos. |
2021-10-21 |
2023-08-12 |
Not clear |
| T A Davis, A Suryawan, R A Orellana, M L Fiorotto, D G Burri. Amino acids and insulin are regulators of muscle protein synthesis in neonatal pigs. Animal : an international journal of animal bioscience. vol 4. issue 11. 2021-10-20. PMID:21779306. |
the enhanced stimulation of muscle protein synthesis in neonates after feeding is independently mediated by the rise in insulin and amino acids and this response declines with age. |
2021-10-20 |
2023-08-12 |
Not clear |
| Li He, Feng-Jiao Zhang, Hao-Yun Li, Lei Li, Li-Ge Song, Yu Mao, Jing Li, Hong-Mei Liu, Feng-Li Li, Ling-Yu Xu, Ya-Jie Huo, Huan-Huan Wang, Fang Luo, Zhi-Qiang Kan. Anti-diabetic Role of Adropin in Streptozotocin Induced Diabetic Rats via Alteration of PI3K/Akt and Insulin Signaling Pathway. Journal of oleo science. vol 70. issue 5. 2021-10-20. PMID:33952790. |
body weight, plasma insulin, blood glucose and food intake were estimated, respectively. |
2021-10-20 |
2023-08-13 |
rat |
| Wen-Ling Cho. Therapeutic potential of targeting intestinal bitter taste receptors in diabetes associated with dyslipidemia. Pharmacological research. vol 170. 2021-10-18. PMID:34048925. |
intestinal release of incretin hormones after food intake promotes glucose-dependent insulin secretion and regulates glucose homeostasis. |
2021-10-18 |
2023-08-13 |
human |
| Signe Schmidt, Christian S Frandsen, Thomas F Dejgaard, Dorte Vistisen, Thórhallur Halldórsson, Sjudur F Olsen, Jens-Erik B Jensen, Sten Madsbad, Henrik U Andersen, Kirsten Nørgaar. Liraglutide changes body composition and lowers added sugar intake in overweight persons with insulin pump-treated type 1 diabetes. Diabetes, obesity & metabolism. 2021-10-18. PMID:34595827. |
to present secondary outcome analyses of liraglutide treatment in overweight adults with insulin pump-treated type 1 diabetes (t1d), focusing on changes in body composition and dimensions, and to evaluate changes in food intake to identify potential dietary drivers of liraglutide-associated weight loss. |
2021-10-18 |
2023-08-13 |
Not clear |
| Jason A West, Anastasia Tsakmaki, Soumitra S Ghosh, David G Parkes, Rikke V Grønlund, Philip J Pedersen, David Maggs, Harith Rajagopalan, Gavin A Bewic. Chronic peptide-based GIP receptor inhibition exhibits modest glucose metabolic changes in mice when administered either alone or combined with GLP-1 agonism. PloS one. vol 16. issue 3. 2021-10-15. PMID:33788878. |
chronic administration studies showed expected effects of liraglutide, lowering food intake, body weight, fasting blood glucose and plasma insulin concentrations while improving glucose sensitivity, whereas delivery of either gipr antagonist alone had negligible effects on these parameters. |
2021-10-15 |
2023-08-13 |
mouse |
| Abdullah S Shatoor, Suliman Al Humayed, Hussain M Almohi. Astaxanthin attenuates hepatic steatosis in high-fat diet-fed rats by suppressing microRNA-21 via transactivation of nuclear factor erythroid 2-related factor 2. Journal of physiology and biochemistry. 2021-10-15. PMID:34651285. |
in the control and hfd-fed rats, asx did not affect food intake, serum free fatty acid (ffa) content, and glucose and insulin levels and tolerance. |
2021-10-15 |
2023-08-13 |
rat |
| Toshiharu Onodera, Ebrahim Ghazvini Zadeh, Peng Xu, Ruth Gordillo, Zheng Guo, Nolwenn Joffin, Biao Yu, Philipp E Scherer, Wen-Hong L. PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions. Journal of lipid research. vol 62. 2021-10-12. PMID:34214600. |
in vivo, adiporonpeg5 can substantially reduce pancreatic, hepatic, and serum ceramide species, with a concomitant increase in the corresponding sphingoid bases and improves insulin sensitivity of mice under hfd feeding conditions. |
2021-10-12 |
2023-08-13 |
mouse |
| Mauricio Castro-Sepúlveda, Béatrice Morio, Mauro Tuñón-Suárez, Sebastian Jannas-Vela, Francisco Díaz-Castro, Jennifer Rieusset, Hermann Zbinden-Fonce. The fasting-feeding metabolic transition regulates mitochondrial dynamics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 35. issue 10. 2021-10-12. PMID:34569666. |
in humans, insulin resistance has been linked to an impaired metabolic transition from fasting to feeding (metabolic flexibility; metflex). |
2021-10-12 |
2023-08-13 |
human |
| Tingting Che, Cheng Yan, Dingyuan Tian, Xin Zhang, Xuejun Liu, Zhongming W. Time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: a randomised controlled trial. Nutrition & metabolism. vol 18. issue 1. 2021-10-11. PMID:34620199. |
time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: a randomised controlled trial. |
2021-10-11 |
2023-08-13 |
Not clear |
| Zhenyan He, Linh Lieu, Yanbin Dong, Sadia Afrin, Dominic Chau, Anita Kabahizi, Briana Wallace, Jianhong Cao, Eun-Sang Hwang, Ting Yao, Yiru Huang, Jennifer Okolo, Bo Cheng, Yong Gao, Ling Hu, Kevin W William. PERK in POMC neurons connects celastrol with metabolism. JCI insight. vol 6. issue 18. 2021-10-09. PMID:34549728. |
male mice deficient for perk in pomc neurons exhibited improvements in energy balance on a high-fat diet, showing decreased food intake and body weight, independent of changes in glucose and insulin tolerances. |
2021-10-09 |
2023-08-13 |
mouse |
| Takeshi Tsuruta, Teresia Aluoch Muhomah, Kei Sonoyama, Qui D Nguyen, Yurika Takase, Aoi Nishijima, Shiori Himoto, Emiko Katsumata, Naoki Nishin. Aicda deficiency exacerbates high-fat diet-induced hyperinsulinemia but not gut dysbiosis in mice. Nutrition research (New York, N.Y.). vol 93. 2021-10-08. PMID:34332207. |
we also found that the fasting blood insulin level was significantly increased by aicda deficiency only under hfd feeding. |
2021-10-08 |
2023-08-13 |
mouse |
| Jennifer Lee, Archana Vijayakumar, Phillip J White, Yuping Xu, Olga Ilkayeva, Christopher J Lynch, Christopher B Newgard, Barbara B Kah. BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis. Endocrinology. vol 162. issue 7. 2021-10-07. PMID:33765118. |
here we examined how high-fat high-sucrose (hfhs) or high-fat diet (hfd) feeding, with or without bcaa supplementation in water, alters the metabolome in serum/plasma and tissues in mice and whether raising circulating bcaa levels worsens insulin resistance and glucose intolerance. |
2021-10-07 |
2023-08-13 |
mouse |