| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christophe Magnan, Stéphanie Migrenne-L. Pleiotropic effects of prokineticin 2 in the control of energy metabolism. Biochimie. vol 186. 2021-08-05. PMID:33932486. |
preclinical models exhibiting disturbances of the prok2 pathway (at the level of prok2 or its receptors) are characterized by changes in food intake, feeding behavior and insulin sensitivity related to a dysfunction of the energy balance control. |
2021-08-05 |
2023-08-13 |
Not clear |
| Jianfeng Liu, Stoyan Dimitrov, Anuck Sawangjit, Jan Born, Ingrid Ehrlich, Manfred Hallschmi. Short-term high-fat feeding induces a reversible net decrease in synaptic AMPA receptors in the hypothalamus. The Journal of nutritional biochemistry. vol 87. 2021-08-04. PMID:33022406. |
high-fat feeding generally increased energy intake, body weight, and serum concentrations of insulin, leptin, free fatty acids, and corticosterone; only the three-day hfd increased wakefulness assessed via video analysis. |
2021-08-04 |
2023-08-13 |
rat |
| Sergio Hidalgo-Figueroa, Ana Rodríguez-Luévano, Julio C Almanza-Pérez, Abraham Giacoman-Martínez, Rolffy Ortiz-Andrade, Ismael León-Rivera, Gabriel Navarrete-Vázque. Synthesis, molecular docking, dynamic simulation and pharmacological characterization of potent multifunctional agent (dual GPR40-PPARγ agonist) for the treatment of experimental type 2 diabetes. European journal of pharmacology. vol 907. 2021-08-03. PMID:34116041. |
finally, compound (1) showed an antihyperglycemic effect at 5 mg/kg, however at higher doses of 25 mg/kg it controlled blood glucose levels associated with feeding intake and without showing the adverse effects associated with insulin secretagogues (hypoglycemia). |
2021-08-03 |
2023-08-13 |
Not clear |
| Dale S Edgerton, Mary C Moore, Justin M Gregory, Guillaume Kraft, Alan D Cherringto. Importance of the route of insulin delivery to its control of glucose metabolism. American journal of physiology. Endocrinology and metabolism. vol 320. issue 5. 2021-07-28. PMID:33813879. |
thus, the hepatoportal insulin gradient is essential to the normal control of glucose metabolism during both fasting and feeding. |
2021-07-28 |
2023-08-13 |
Not clear |
| Mobina Alemi, Ângela Oliveira, Sofia C Tavares, José Ricardo Vieira, Marco G Alves, Pedro F Oliveira, Isabel Cardos. Exploring the Physiological Role of Transthyretin in Glucose Metabolism in the Liver. International journal of molecular sciences. vol 22. issue 11. 2021-07-26. PMID:34199897. |
it has been shown that ttr is involved in several functions, such as insulin release from pancreatic β-cells, recovery of blood glucose and glucagon levels of the islets of langerhans, food intake, and body weight. |
2021-07-26 |
2023-08-13 |
mouse |
| Anna Fosch, Sebastián Zagmutt, Núria Casals, Rosalía Rodríguez-Rodrígue. New Insights of SF1 Neurons in Hypothalamic Regulation of Obesity and Diabetes. International journal of molecular sciences. vol 22. issue 12. 2021-07-26. PMID:34201257. |
in the last 15 years, investigations using transgenic models, optogenetic, and chemogenetic approaches have revealed that sf1 neurons in the ventromedial hypothalamus are a specific lead in the brain's ability to sense glucose levels and conduct insulin and leptin signaling in energy expenditure and glucose homeostasis, with minor feeding control. |
2021-07-26 |
2023-08-13 |
Not clear |
| Benjarat Janson, Janjira Prasomthong, Wachirawadee Malakul, Tantip Boonsong, Sakara Tunsopho. Hibiscus sabdariffa L. calyx extract prevents the adipogenesis of 3T3-L1 adipocytes, and obesity-related insulin resistance in high-fat diet-induced obese rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 138. 2021-07-22. PMID:33721756. |
the results demonstrated that roselle had the potential to reduce body weight, food intake, lipid profiles, inflammatory cytokines, lipid peroxidation, serum leptin, insulin and duodenal glucose absorption, while significantly increased glucose uptake of adipose tissue and muscle when compared to the hfd group. |
2021-07-22 |
2023-08-13 |
rat |
| Qitong Lu, Rui Zheng, Pengcheng Zhu, Jinhui Bian, Zhiyong Liu, Junjie D. Hinokinin alleviates high fat diet/streptozotocin-induced cardiac injury in mice through modulation in oxidative stress, inflammation and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-20. PMID:33761596. |
the type 2 diabetic mice exhibited a rise in blood glucose level as well as glycated hemoglobin (hba1c %), decrease in weekly body weights, decrease in food intake, reduction in absolute heart weight, fall in serum insulin level with altered lipid profile and cardiac functional damage. |
2021-07-20 |
2023-08-13 |
mouse |
| Jiawei Zhou, Feng Wang, Juanjuan Chen, Rui Yang, Yuhao Chen, Denghui Gu, Tingting Niu, Qijun Luo, Xiaojun Yan, Haimin Chen, Wei W. Long-term kappa-carrageenan consumption leads to moderate metabolic disorder by blocking insulin binding. Pharmacological research. vol 165. 2021-07-16. PMID:33401003. |
in summary, this study revealed that κ-cgn reduced weight gain without affecting food intake, but impaired glucose metabolism in mice by interfering with insulin binding to receptors, thereby affecting the sensitivity of insulin and inhibiting the insulin pi3k/akt signaling pathway, causing non-diabetic weight gain reduction. |
2021-07-16 |
2023-08-13 |
mouse |
| Sarah Koop, Henrik Oste. Eat, sleep, repeat - endocrine regulation of behavioural circadian rhythms. The FEBS journal. 2021-07-16. PMID:34228879. |
food intake, in contrast, receives circadian modulation through hormones such as leptin, ghrelin, insulin and orexin. |
2021-07-16 |
2023-08-13 |
Not clear |
| Aleksandra Mieczkowska, Paul Millar, Daniel Chappard, Victor A Gault, Guillaume Mabillea. Dapagliflozin and Liraglutide Therapies Rapidly Enhanced Bone Material Properties and Matrix Biomechanics at Bone Formation Site in a Type 2 Diabetic Mouse Model. Calcified tissue international. vol 107. issue 3. 2021-07-14. PMID:32642787. |
combined low-dose streptozotocin and high fat feeding were employed in mice to promote obesity, insulin resistance, and hyperglycaemia. |
2021-07-14 |
2023-08-13 |
mouse |
| Uma D Kabra, Charles Affourtit, Martin Jastroc. Respiratory Parameters for the Classification of Dysfunctional Insulin Secretion by Pancreatic Islets. Metabolites. vol 11. issue 6. 2021-07-14. PMID:34205530. |
we metabolically stressed male c57bl/6 mice by high-fat feeding (hfd) and measured the glucose sensitivity of islet respiration and insulin secretion. |
2021-07-14 |
2023-08-13 |
mouse |
| Alie J Johnston, Rebecca C Mollard, Dianna Dandeneau, Dylan S MacKay, Nancy Ames, Julianne Curran, Danielle R Bouchard, Peter J Jone. Acute effects of extruded pulse snacks on glycemic response, insulin, appetite, and food intake in healthy young adults in a double blind, randomized, crossover trial. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 46. issue 7. 2021-07-08. PMID:33347383. |
acute effects of extruded pulse snacks on glycemic response, insulin, appetite, and food intake in healthy young adults in a double blind, randomized, crossover trial. |
2021-07-08 |
2023-08-13 |
Not clear |
| Celso Pereira Batista Sousa-Filho, Hector Oreliana Fernandes Faria, Juliana Carvalho Esposito, Alessandra Melo, Miriam Oliveira Ribeiro, Rosemari Otto. Green tea improves the metabolism of peripheral tissues in β3-adrenergic receptor-knockout mice. Pharmacological research. vol 159. 2021-07-06. PMID:32480000. |
gt-treatment attenuated final bw, bw gain, and adiposity index increased by hfd, improving insulin resistance (ir) and fgf21 level, without changing the food intake of wt mice. |
2021-07-06 |
2023-08-13 |
mouse |
| Xu Han, Xiaoyan Chen, Xuan Wang, Meirong Gong, Mengjiang Lu, Zhi Yu, Bin Xu, Jinhong Yua. Electroacupuncture at ST36 Improve the Gastric Motility by Affecting Neurotransmitters in the Enteric Nervous System in Type 2 Diabetic Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-07-06. PMID:34221088. |
ea treatment reduced the body weight, food intake, and blood glucose; improved glucose intolerance and insulin resistance; increased the gastric emptying rate, the mean antral pressure, and the amplitude of antral motility; and decreased the frequency of antral motility compared with those in the dm group. |
2021-07-06 |
2023-08-13 |
rat |
| Raul C Camacho, Seohee You, Katharine E D'Aquino, Wenyu Li, Yuanping Wang, Joseph Gunnet, James Littrell, Jian Shen Qi, Lijuan Kang, Wenying Jian, Mary MacDonald, Timothy Tat, Derek Steiner, Yue-Mei Zhang, James Lanter, Raymond Patch, Rui Zhang, Jiali Li, Suzanne Edavettal, Wilson Edwards, Thai Dinh, Li Ying Wang, Judy Connor, Michael Hunter, Ellen Chi, Ronald V Swanson, James N Leonard, Martin A Cas. Conjugation of a peptide to an antibody engineered with free cysteines dramatically improves half-life and activity. mAbs. vol 12. issue 1. 2021-07-05. PMID:32744157. |
a single dose of the long-acting peptide conjugate robustly inhibited food intake and decreased body weight in insulin resistant diet-induced obese mice, in addition to ameliorating glucose intolerance. |
2021-07-05 |
2023-08-13 |
mouse |
| Liwei Zhang, Wen Chu, Lei Zheng, Juanjuan Li, Yuling Ren, Liping Xue, Wenhua Duan, Qing Wang, Hua L. Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32692483. |
also, the effect of cr-znonps on drp-induced rats was determined by food intake, fasting blood glucose (fbg), hba1c, insulin, retina thickness, inner nuclear layer (inl), outer nuclear layer (onl) thickness, lipid peroxidation (lpo), catalase (cat), glutathione peroxidase (gpx), and superoxide dismutase (sod). |
2021-07-02 |
2023-08-13 |
rat |
| Liwei Zhang, Wen Chu, Lei Zheng, Juanjuan Li, Yuling Ren, Liping Xue, Wenhua Duan, Qing Wang, Hua L. Zinc oxide nanoparticles from Cyperus rotundus attenuates diabetic retinopathy by inhibiting NLRP3 inflammasome activation in STZ-induced diabetic rats. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32692483. |
the administration of streptozotocin (stz)-induced drp rats were increased in the levels of hba1c, fbg, food intake, lpo, and reduced levels of insulin, sod, gpx, and cat. |
2021-07-02 |
2023-08-13 |
rat |
| Howard Wolpert, William H Polonsky, David Rodbar. Insulin Metrics: Need for Development of Consensus Standards for Reporting of Insulin Dosing Data. Diabetes technology & therapeutics. vol 23. issue 7. 2021-07-02. PMID:33523768. |
there is a need for the diabetes community to develop standards for such data, analogous to what has been achieved using the ambulatory glucose profile and associated metrics for glucose, permitting harmonization of data reporting for multiple devices and facilitating integration of glucose, insulin, food intake, and physical activity data. |
2021-07-02 |
2023-08-13 |
Not clear |
| Gohar Sedaghat, Farzaneh Montazerifar, Mahmood Ali Keykhaie, Mansour Karajibani, Shadi Shourestani, Alireza Dashipou. Effect of pre-meal water intake on the serum levels of Copeptin, glycemic control, lipid profile and anthropometric indices in patients with type 2 diabetes mellitus: a randomized, controlled trial. Journal of diabetes and metabolic disorders. vol 20. issue 1. 2021-06-29. PMID:34178828. |
water pre-load affects insulin secretion by altering the level of copeptin (c-terminal component of the arginine vasopressin hormone (avp)) and preventing obesity by reducing food intake. |
2021-06-29 |
2023-08-13 |
Not clear |