| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Heiko T Jansen, Brandon Evans Hutzenbiler, Hannah R Hapner, Madeline L McPhee, Anthony M Carnahan, Joanna L Kelley, Michael W Saxton, Charles T Robbin. Can offsetting the energetic cost of hibernation restore an active season phenotype in grizzly bears (Ursus arctos horribilis)? The Journal of experimental biology. vol 224. issue 12. 2021-06-28. PMID:34137891. |
the partial depression of circulating ffas with feeding likely explains the incomplete restoration of insulin sensitivity and other metabolic parameters in hibernating bears. |
2021-06-28 |
2023-08-13 |
Not clear |
| b' Miroslava Kac\\xc3\\xad\\xc5\\x99ov\\xc3\\xa1, Blanka \\xc5\\xbdelezn\\xc3\\xa1, Michaela Bla\\xc5\\xbekov\\xc3\\xa1, Martina Holubov\\xc3\\xa1, Andrea Popelov\\xc3\\xa1, Jaroslav Kune\\xc5\\xa1, Blanka \\xc5\\xa0ediv\\xc3\\xa1, Lenka Malet\\xc3\\xadnsk\\xc3\\xa. Aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology THY-Tau22. Journal of neuroinflammation. vol 18. issue 1. 2021-06-26. PMID:34158075.' |
aging and high-fat diet feeding lead to peripheral insulin resistance and sex-dependent changes in brain of mouse model of tau pathology thy-tau22. |
2021-06-26 |
2023-08-13 |
mouse |
| Sophia J Wiedemann, Leila Rachid, Ben Illigens, Marianne Böni-Schnetzler, Marc Y Donat. Evidence for cephalic phase insulin release in humans: A systematic review and meta-analysis. Appetite. vol 155. 2021-06-24. PMID:32707265. |
insulin has been shown to act centrally to regulate food intake and glucose metabolism and the cephalic phase of insulin secretion may contribute to these functions. |
2021-06-24 |
2023-08-13 |
human |
| Richard Kehm, Markus Jähnert, Stefanie Deubel, Tanina Flore, Jeannette König, Tobias Jung, Mandy Stadion, Wenke Jonas, Annette Schürmann, Tilman Grune, Annika Höh. Redox homeostasis and cell cycle activation mediate beta-cell mass expansion in aged, diabetes-prone mice under metabolic stress conditions: Role of thioredoxin-interacting protein (TXNIP). Redox biology. vol 37. 2021-06-18. PMID:33128997. |
interestingly, while young nzo mice developed massive hyperglycemia in response to carbohydrate feeding, leading to beta-cell dysfunction and cell death, aged counterparts compensated the increased insulin demand by persistent beta-cell function and beta-cell mass expansion. |
2021-06-18 |
2023-08-13 |
mouse |
| Huashan Gao, Qian Zhao, Kaiying Li, Fujian Qin, Xin Yin, Zhou Lu, Ziwei Song, You Wu, Yumeng Shen, Yi Pan, Liang Jin, Yanfeng Zhan. EGLP-1 lowers body weight better than exendin-4 by reducing food intake and increasing basal energy expenditure in diet-induced obese mice. Experimental cell research. vol 399. issue 1. 2021-06-15. PMID:33359447. |
at the same time, eglp-1 can improve hyperglycemia, reduce food intake, and improve insulin resistance, just like exendin-4. |
2021-06-15 |
2023-08-13 |
mouse |
| Manfred Hallschmi. Intranasal insulin. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33506526. |
two decades of studies in healthy humans and patients have demonstrated that in insulin exerts functional effects on metabolism, such as reductions in food intake and body weight and improvements of glucose homeostasis, as well as cognition, ie, enhancements of memory performance both in healthy individuals and patients with mild cognitive impairment or alzheimer's disease; these studies moreover indicate a favourable safety profile of the acute and repeated use of in insulin. |
2021-06-15 |
2023-08-13 |
Not clear |
| Teppei Fujikaw. Central regulation of glucose metabolism in an insulin-dependent and -independent manner. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33599044. |
additionally, insulin also acts on the brain to regulate food intake and fat metabolism, which may indirectly regulate glucose metabolism. |
2021-06-15 |
2023-08-13 |
Not clear |
| Alisa Boucsein, Kaj Kamstra, Alexander Tup. Central signalling cross-talk between insulin and leptin in glucose and energy homeostasis. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33615588. |
the peripheral adiposity signals insulin and leptin play a crucial role in this system by informing the brain of the energy status of the body and mediating their catabolic effects through signal transduction in hypothalamic areas that control food intake, energy expenditure and glucose metabolism. |
2021-06-15 |
2023-08-13 |
human |
| Caitlin S Mitchell, Denovan P Beg. The regulation of food intake by insulin in the central nervous system. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33656205. |
the regulation of food intake by insulin in the central nervous system. |
2021-06-15 |
2023-08-13 |
Not clear |
| Caitlin S Mitchell, Denovan P Beg. The regulation of food intake by insulin in the central nervous system. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33656205. |
unlike peripheral administration of insulin, which often causes weight gain, central administration of insulin leads to a reduction in food intake and body weight when administered long-term. |
2021-06-15 |
2023-08-13 |
Not clear |
| Caitlin S Mitchell, Denovan P Beg. The regulation of food intake by insulin in the central nervous system. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33656205. |
insulin infusion into the central nucleus of the amygdala (cea) can decrease food intake, possibly by modulating activity of npy and other neurone subpopulations. |
2021-06-15 |
2023-08-13 |
Not clear |
| Sharon R Ladyman, Virginia L Brook. Central actions of insulin during pregnancy and lactation. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33710714. |
moreover, we explore the hypothesis that pregnancy is associated with site-specific central insulin resistance that is adaptive, allowing for the increases in peripheral insulin secretion without the consequences of increased central and peripheral insulin functions, such as to stimulate glucose uptake into maternal tissues or to inhibit food intake. |
2021-06-15 |
2023-08-13 |
Not clear |
| Frederick Wasinski, Fernanda M Chaves, João A B Pedroso, Naira S Mansano, João Paulo Camporez, Daniela O Gusmão, Edward O List, John J Kopchick, Renata Frazão, Raphael E Szawka, Jose Donat. Growth hormone receptor in dopaminergic neurones regulates stress-induced prolactin release in male mice. Journal of neuroendocrinology. vol 33. issue 3. 2021-06-15. PMID:33769619. |
ghr deletion in dat- or th-expressing cells did not cause changes in food intake, energy expenditure, ambulatory activity, nutrient oxidation, glucose tolerance, insulin sensitivity and counter-regulatory response to hypoglycaemia in male and female mice. |
2021-06-15 |
2023-08-13 |
mouse |
| Nada A Sallam, Stephanie L Borglan. Insulin and endocannabinoids in the mesolimbic system. Journal of neuroendocrinology. vol 33. issue 4. 2021-06-15. PMID:33856071. |
insulin and endocannabinoids (ecbs) are two major, presumably opposing, players in regulating homeostatic and non-homeostatic feeding centrally and peripherally. |
2021-06-15 |
2023-08-13 |
Not clear |
| Béatrice S-Y Choi, Noëmie Daniel, Vanessa P Houde, Adia Ouellette, Bruno Marcotte, Thibault V Varin, Cécile Vors, Perrine Feutry, Olga Ilkayeva, Marcus Ståhlman, Philippe St-Pierre, Fredrik Bäckhed, Angelo Tremblay, Phillip J White, André Marett. Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice. Nature communications. vol 12. issue 1. 2021-06-15. PMID:34099716. |
feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mtorc1 signaling in obese mice. |
2021-06-15 |
2023-08-13 |
mouse |
| Z Khant Aung, D R Grattan, S R Ladyma. Pregnancy-induced adaptation of central sensitivity to leptin and insulin. Molecular and cellular endocrinology. vol 516. 2021-06-14. PMID:32707081. |
central effects of leptin and insulin, however, are counterproductive to pregnancy, as increased action of these hormones in the brain lead to suppression of food intake. |
2021-06-14 |
2023-08-13 |
Not clear |
| Qiang Li, Chenxu Ge, Jun Tan, Yan Sun, Qin Kuang, Xianling Dai, Shaoyu Zhong, Chao Yi, Lin-Feng Hu, De-Shuai Lou, Minxuan X. Juglanin protects against high fat diet-induced renal injury by suppressing inflammation and dyslipidemia via regulating NF-κB/HDAC3 signaling. International immunopharmacology. vol 95. 2021-06-10. PMID:33667999. |
our results suggested that chronic hfd feeding markedly increased the body weights of mice compared to the ones fed with normal chow diet (ncd), along with significant glucose intolerance and insulin resistance. |
2021-06-10 |
2023-08-13 |
mouse |
| Sandra Aparecida Benite-Ribeiro, Valkíria Alves de Lima Rodrigues, Mônica Rodrigues Ferreira Machad. Food intake in early life and epigenetic modifications of pro-opiomelanocortin expression in arcuate nucleus. Molecular biology reports. vol 48. issue 4. 2021-06-09. PMID:33877530. |
the control of food intake is performed by neurons of the arcuate nucleus of the hypothalamus (arc), which secret orexigenic and anorexigenic neuropeptides, such as proopiomelanocortin (pomc), under stimulation of, e.g., ghrelin, insulin, and leptin. |
2021-06-09 |
2023-08-13 |
Not clear |
| Sanathoibi D Kh, Bela Kesha. Larval feeding status regulates the transcript levels of genes encoding PTTH and allatoregulatory peptides in silkworm Bombyx mori. Insect science. vol 28. issue 3. 2021-06-08. PMID:32401387. |
at feeding, the insulin decreased the ptth expression level, while at food deprivation, the insulin increased the ptth expression level. |
2021-06-08 |
2023-08-13 |
Not clear |
| Lin-Shan Jiang, Wei Li, Tong-Xi Zhuang, Jie-Jing Yu, Shuai Sun, Zheng-Cai Ju, Zheng-Tao Wang, Li-Li Ding, Li Yan. Ginsenoside Ro Ameliorates High-Fat Diet-Induced Obesity and Insulin Resistance in Mice via Activation of the G Protein-Coupled Bile Acid Receptor 5 Pathway. The Journal of pharmacology and experimental therapeutics. vol 377. issue 3. 2021-06-07. PMID:33820830. |
our results showed that the ginsenoside ro (90mg/kg) treatment ameliorated body weight and lipid accumulation in multiple metabolic organs of high-fat diet-induced obese (dio) mice without affecting food intake and improved oral glucose tolerance tests, intraperitoneal insulin tolerance tests, and fasting serum glucose. |
2021-06-07 |
2023-08-13 |
mouse |