| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xueping Yang, Fan Wu, Lingli Li, Ernest C Lynch, Linglin Xie, Yan Zhao, Ke Fang, Jingbin Li, Jinlong Luo, Lijun Xu, Xin Zou, Fuer Lu, Guang Che. Celastrol alleviates metabolic disturbance in high-fat diet-induced obese mice through increasing energy expenditure by ameliorating metabolic inflammation. Phytotherapy research : PTR. vol 35. issue 1. 2021-03-04. PMID:32776627. |
our results showed that celastrol can reduce weight gain, ameliorate glucose intolerance, insulin resistance, and dyslipidemia without affecting food intake in high-fat diet-induced obese mice. |
2021-03-04 |
2023-08-13 |
mouse |
| Maria Izabel Siqueira de Andrade, Juliana Souza Oliveira, Vanessa Sá Leal, Niedja Maria da Silva Lima, Phelipe Bibiano Bezerra, Emerson Rogério Costa Santiago, Pedro Israel Cabral de Lir. PREVALENCE OF INSULIN RESISTANCE AND ASSOCIATION WITH METABOLIC RISK FACTORS AND FOOD CONSUMPTION IN ADOLESCENTS - RECIFE/BRAZIL. Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo. vol 38. 2021-03-02. PMID:32187300. |
to identify the prevalence of insulin resistance in adolescents and its associations with metabolic factors and food intake. |
2021-03-02 |
2023-08-13 |
Not clear |
| Mandy Ho, G Harvey Anderson, Lin Lin, Richard P Bazinet, Ruslan Kuban. Ethanolamides of essential α-linolenic and linoleic fatty acids suppress short-term food intake in rats. Food & function. vol 11. issue 4. 2021-03-02. PMID:32191234. |
short-term food intake, plasma and brain fae status, and plasma concentrations of insulin and leptin were measured to determine whether these hormones mediate the anorectic effect of faes. |
2021-03-02 |
2023-08-13 |
rat |
| Mandy Ho, G Harvey Anderson, Lin Lin, Richard P Bazinet, Ruslan Kuban. Ethanolamides of essential α-linolenic and linoleic fatty acids suppress short-term food intake in rats. Food & function. vol 11. issue 4. 2021-03-02. PMID:32191234. |
both ethanolamides, but not their parent fatty acids, acutely suppressed food intake up to one hour post-treatment and this effect was independent of insulin and leptin hormones. |
2021-03-02 |
2023-08-13 |
rat |
| Olha M Strilbytska, Uliana V Semaniuk, Kenneth B Storey, Ihor S Yurkevych, Oleh Lushcha. Insulin Signaling in Intestinal Stem and Progenitor Cells as an Important Determinant of Physiological and Metabolic Traits in Cells. vol 9. issue 4. 2021-02-25. PMID:32225024. |
insulin signaling in intestinal stem and progenitor cells as an important determinant of physiological and metabolic traits in the insulin-igf-1 signaling (iis) pathway is conserved throughout multicellular organisms and regulates many traits, including aging, reproduction, feeding, metabolism, stress resistance, and growth. |
2021-02-25 |
2023-08-13 |
Not clear |
| Claes Fryklund, Madelene Borg, Tobias Svensson, Sara Schumacher, Florentina Negoita, Björn Morén, Karin G Stenkul. Impaired glucose transport in inguinal adipocytes after short-term high-sucrose feeding in mice. The Journal of nutritional biochemistry. vol 78. 2021-02-23. PMID:32004930. |
altogether, we demonstrate that short-term hsd feeding has deleterious impact on insulin response and glucose transport in the inguinal adipose tissue depot, specifically. |
2021-02-23 |
2023-08-13 |
mouse |
| Daniela Regazzo, Mattia Barbot, Carla Scaroni, Nora Albiger, Gianluca Occh. The pathogenic role of the GIP/GIPR axis in human endocrine tumors: emerging clinical mechanisms beyond diabetes. Reviews in endocrine & metabolic disorders. vol 21. issue 1. 2021-02-16. PMID:31933128. |
gip has a variety of effects on different systems, including the potentiation of insulin secretion from pancreatic β-cells after food intake (i.e. |
2021-02-16 |
2023-08-13 |
human |
| Renan Fudoli Lins Vieira, Vitor Rosetto Muñoz, Rafael Lima Junqueira, Fellipe de Oliveira, Rafael Calais Gaspar, Susana Castelo Branco Ramos Nakandakari, Suleyma de Oliveira Costa, Marcio Alberto Torsoni, Adelino S R da Silva, Dennys Esper Cintra, Leandro Pereira de Moura, Eduardo Rochete Ropelle, Iman Zaghloul, Rania A Mekary, José Rodrigo Paul. Time-restricted feeding combined with aerobic exercise training can prevent weight gain and improve metabolic disorders in mice fed a high-fat diet. The Journal of physiology. 2021-02-16. PMID:33450053. |
trf combined with ae training attenuated the detrimental effects of high-fat diet feeding on the insulin signalling pathway in the liver. |
2021-02-16 |
2023-08-13 |
mouse |
| Jian Qiu, Martha A Bosch, Chungang Zhang, Oline K Rønnekleiv, Martin J Kell. Estradiol Protects Neuropeptide Y/Agouti-Related Peptide Neurons against Insulin Resistance in Females. Neuroendocrinology. vol 110. issue 1-2. 2021-02-15. PMID:31212279. |
since the anorexigenic hormone 17β-estradiol (e2) regulates food intake in part by inhibiting the excitability of the hypothalamic neuropeptide y/agouti-related peptide (npy/agrp) neurons, we hypothesized that e2 would protect against insulin resistance in npy/agrp neurons with diet-induced obesity (dio). |
2021-02-15 |
2023-08-13 |
mouse |
| Akira Kitagawa, Yoshiji Ohta, Koji Ohashi, Koji Yashiro, Kenji Fukuzaw. Effect of High Fructose-Induced Metabolic Syndrome on Tissue Vitamin E and Lipid Peroxide Levels in Rats. Journal of nutritional science and vitaminology. vol 66. issue 2. 2021-02-10. PMID:32350182. |
feeding of a diet containing 60% fructose (hfd) to wistar rats for 2, 4, and 6 wk caused week-dependent increases in homa-ir score and serum insulin, triglyceride, total cholesterol, and free fatty acid concentrations. |
2021-02-10 |
2023-08-13 |
rat |
| Alejandro A Floh, Brian W McCrindle, Cedric Manlhiot, Masayuki Nakada, Gustavo La Rotta, Glen Van Arsdell, Steven M Schwart. Feeding May Modulate the Relationship Between Systemic Inflammation, Insulin Resistance, and Poor Outcome Following Cardiopulmonary Bypass for Pediatric Cardiac Surgery. JPEN. Journal of parenteral and enteral nutrition. vol 44. issue 2. 2021-02-08. PMID:30887547. |
feeding may modulate the relationship between systemic inflammation, insulin resistance, and poor outcome following cardiopulmonary bypass for pediatric cardiac surgery. |
2021-02-08 |
2023-08-13 |
Not clear |
| Nigel Irwin, Victor A Gault, Finbarr P M O'Harte, Peter R Flat. Blockade of gastric inhibitory polypeptide (GIP) action as a novel means of countering insulin resistance in the treatment of obesity-diabetes. Peptides. vol 125. 2021-02-08. PMID:31733230. |
sustained administration of peptide-based gipr inhibitors, low molecular weight gipr antagonists, gipr neutralising antibodies as well as genetic knockout of gipr's or vaccination against gip all demonstrate amelioration of insulin resistance and reduced body weight gain in response to high fat feeding. |
2021-02-08 |
2023-08-13 |
Not clear |
| Koji Ohashi, Yoshiji Ohta, Hiroaki Ishikawa, Akira Kitagaw. Orally administered octacosanol improves some features of high fructose-induced metabolic syndrome in rats. Journal of clinical biochemistry and nutrition. vol 68. issue 1. 2021-02-06. PMID:33536713. |
three- or four-week high fructose feeding increased insulin resistance, serum insulin, triglyceride, total cholesterol, free fatty acids, uric acid, and lipid peroxide concentrations, and hepatic triglyceride and cholesterol contents significantly and decreased serum high-density lipoprotein cholesterol and adiponectin concentrations significantly but did not affect blood pressure and hepatic lipid peroxide and reduced glutathione contents. |
2021-02-06 |
2023-08-13 |
rat |
| Koji Ohashi, Yoshiji Ohta, Hiroaki Ishikawa, Akira Kitagaw. Orally administered octacosanol improves some features of high fructose-induced metabolic syndrome in rats. Journal of clinical biochemistry and nutrition. vol 68. issue 1. 2021-02-06. PMID:33536713. |
oral administration of octacosanol (10 or 50 mg/kg body weight) to high fructose-fed rats for the last 1-week fructose diet feeding attenuated these changes except serum insulin level and insulin resistance significantly and increased hepatic reduced glutathione content significantly. |
2021-02-06 |
2023-08-13 |
rat |
| Chak Kwong Cheng, Chenguang Wang, Wenbin Shang, Chi Wai Lau, Jiang-Yun Luo, Li Wang, Yu Huan. A high methionine and low folate diet alters glucose homeostasis and gut microbiome. Biochemistry and biophysics reports. vol 25. 2021-02-06. PMID:33537464. |
the hmlf diet feeding resulted in a progressive body weight loss, and development of slight glucose intolerance and insulin resistance in hhcy mice. |
2021-02-06 |
2023-08-13 |
mouse |
| Xiao Wang, Shuchang Lai, Yanshi Ye, Yuanyuan Hu, Daoyan Pan, Xiaochun Bai, Jie She. Conditional knockout of pyruvate dehydrogenase in mouse pancreatic β‑cells causes morphological and functional changes. Molecular medicine reports. vol 21. issue 4. 2021-02-03. PMID:32319629. |
though no changes were found in food intake, development status, fasting blood glucose or weight between the groups, the level of insulin secretion at 30 min after glucose injection in the βko group was significantly lower compared with the control group. |
2021-02-03 |
2023-08-13 |
mouse |
| Yan Liu, Haiyan Lin, Lin Jiang, Qingsen Shang, Lei Yin, Jiandie D Lin, Wen-Shu Wu, Liangyou Ru. Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes. The Journal of clinical investigation. vol 130. issue 6. 2021-02-02. PMID:32365055. |
hepatic slug levels were markedly upregulated in mice by either feeding or insulin treatment. |
2021-02-02 |
2023-08-13 |
mouse |
| John L Sievenpipe. Low-carbohydrate diets and cardiometabolic health: the importance of carbohydrate quality over quantity. Nutrition reviews. vol 78. issue Suppl 1. 2021-02-02. PMID:32728757. |
although the clinical investigations of the "carbohydrate-insulin model" have shown the requisite decreases in insulin secretion and increases in fat oxidation, there has been a failure to achieve the expected fat loss under low-carbohydrate feeding. |
2021-02-02 |
2023-08-13 |
Not clear |
| Xu Si, Jinlong Tian, Chi Shu, Yuehua Wang, Ersheng Gong, Ye Zhang, Weijia Zhang, Huijun Cui, Bin L. Serum Ceramide Reduction by Blueberry Anthocyanin-Rich Extract Alleviates Insulin Resistance in Hyperlipidemia Mice. Journal of agricultural and food chemistry. vol 68. issue 31. 2021-01-27. PMID:32692177. |
a bae-containing diet effectively controlled food intake and liver weight and significantly attenuated insulin resistance triggered by a hfd. |
2021-01-27 |
2023-08-13 |
mouse |
| Hui Deng, Weimin L. Therapeutic potential of targeting α/β-Hydrolase domain-containing 6 (ABHD6). European journal of medicinal chemistry. vol 198. 2021-01-26. PMID:32371333. |
abhd6 and its substrates have been shown to be involved in the modulation of various (patho)physiological processes, including neurotransmission, inflammation, insulin secretion, adipose browning, food intake, autoimmune disorders, as well as neurological and metabolic diseases, making this enzyme a promising therapeutic target to treat several diseases. |
2021-01-26 |
2023-08-13 |
Not clear |