Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Anup Bhusal, Md Habibur Rahman, Kyoungho Su. Hypothalamic inflammation in metabolic disorders and aging. Cellular and molecular life sciences : CMLS. 2021-12-15. PMID:34910246. |
this activation of different cell types in the hypothalamus leads to chronic, low-grade inflammation, impairing energy balance and contributing to defective feeding habits, thermogenesis, and insulin and leptin signaling, eventually leading to metabolic disorders (i.e., diabetes, obesity, and hypertension). |
2021-12-15 |
2023-08-13 |
Not clear |
Carin Weirich Gallon, Charles Francisco Ferreira, Aline Henz, Carolina Leão Oderich, Maiara Conzatti, Juliana Ritondale Sodré de Castro, Matheus Parmegiani Jahn, Keoma da Silva, Maria Celeste Osório Wende. Leptin, ghrelin, & insulin levels and food intake in premenstrual syndrome: A case-control study. Appetite. vol 168. 2021-12-11. PMID:34648911. |
leptin, ghrelin, & insulin levels and food intake in premenstrual syndrome: a case-control study. |
2021-12-11 |
2023-08-13 |
human |
P M Cline, T C Tsai, C A Lents, A M Stelzleni, C R Dove, M Azai. Interaction of dietary carbohydrate and fat on glucose metabolism in growing pigs. Domestic animal endocrinology. vol 78. 2021-12-09. PMID:34478942. |
rodent studies have shown an increase in de novo lipogenesis and decreased insulin sensitivity in response to feeding high levels of fructose, but it is unclear if these effects occur in the same progression in humans. |
2021-12-09 |
2023-08-13 |
Not clear |
Takao Ito, Yuta Yamamoto, Naoko Yamagishi, Yoshimitsu Kana. Stomach secretes estrogen in response to the blood triglyceride levels. Communications biology. vol 4. issue 1. 2021-12-09. PMID:34876651. |
ghrelin, insulin, leptin and vagal afferents transmit the status of fasting, blood glucose, body fat, and food intake, respectively. |
2021-12-09 |
2023-08-13 |
Not clear |
A Ortín-Bustillo, A Tvarijonaviciute, J J Cerón, M D Contreras-Aguilar, S Martínez-Miró, S Martínez-Subiela, F Tecles, A Muñoz-Priet. Insulin in the saliva of pigs: Validation of an automated assay and changes at different physiological conditions. Research in veterinary science. vol 141. 2021-12-08. PMID:34715588. |
in addition, the possible changes of salivary insulin concentration in sows after food intake and during gestation and lactation were studied. |
2021-12-08 |
2023-08-13 |
Not clear |
A Ortín-Bustillo, A Tvarijonaviciute, J J Cerón, M D Contreras-Aguilar, S Martínez-Miró, S Martínez-Subiela, F Tecles, A Muñoz-Priet. Insulin in the saliva of pigs: Validation of an automated assay and changes at different physiological conditions. Research in veterinary science. vol 141. 2021-12-08. PMID:34715588. |
insulin concentrations showed a significant increase in the saliva of sows after feeding. |
2021-12-08 |
2023-08-13 |
Not clear |
A Ortín-Bustillo, A Tvarijonaviciute, J J Cerón, M D Contreras-Aguilar, S Martínez-Miró, S Martínez-Subiela, F Tecles, A Muñoz-Priet. Insulin in the saliva of pigs: Validation of an automated assay and changes at different physiological conditions. Research in veterinary science. vol 141. 2021-12-08. PMID:34715588. |
in conclusion, the results showed that insulin could be measured in the saliva of pigs, and changes in its concentration can be detected due to food intake and different physiological conditions. |
2021-12-08 |
2023-08-13 |
Not clear |
Robert J Shulma. Comment on: Efficacy and safety of enteral recombinant human insulin for reduction of time-to-full enteral feeding in preterm infants: a randomized, double-blind, placebo-controlled trial (IMAJ September 2021). The Israel Medical Association journal : IMAJ. vol 23. issue 11. 2021-12-08. PMID:34811995. |
comment on: efficacy and safety of enteral recombinant human insulin for reduction of time-to-full enteral feeding in preterm infants: a randomized, double-blind, placebo-controlled trial (imaj september 2021). |
2021-12-08 |
2023-08-13 |
human |
Maximilian A McCann, Yanliang Li, Marcos Muñoz, Victoria Gil, Guifen Qiang, Jose Cordoba-Chacon, Matthias Blüher, Stephen Duncan, Chong Wee Lie. Adipose expression of CREB3L3 modulates body weight during obesity. Scientific reports. vol 11. issue 1. 2021-12-07. PMID:34588527. |
fat-specific ablation of creb3l3 enhanced weight gain and insulin resistance following high-fat feeding, as fat-specific knockout mice expended less energy and possessed more inflammatory adipose tissue. |
2021-12-07 |
2023-08-13 |
mouse |
Jari-Pekka Klemettilä, Anssi Solismaa, Niko Seppälä, Mari Hämäläinen, Eeva Moilanen, Esa Leinonen, Olli Kampma. Glucagon-like peptide-1 serum levels are associated with weight gain in patients treated with clozapine. Psychiatry research. vol 306. 2021-12-06. PMID:34610543. |
glucagon-like peptide-1 (glp-1) is involved in insulin secretion, regulation of satiety, inhibition of food intake, and inhibition of gastric emptying. |
2021-12-06 |
2023-08-13 |
Not clear |
Samnhita Raychaudhuri, Si Fan, Olivia Kraus, Md Shahinozzaman, Diana N Oband. Kale supplementation during high fat feeding improves metabolic health in a mouse model of obesity and insulin resistance. PloS one. vol 16. issue 8. 2021-12-02. PMID:34432833. |
kale supplementation during high fat feeding improves metabolic health in a mouse model of obesity and insulin resistance. |
2021-12-02 |
2023-08-13 |
mouse |
Alpana Mukhuty, Chandrani Fouzder, Rakesh Kund. Fetuin-A secretion from β-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion. Journal of cell science. vol 134. issue 21. 2021-12-02. PMID:34643217. |
furthermore, high-fat feeding in mice showed elevated cytokine and fetuin-a content in serum and islets, and also migration and polarization of macrophages to the islets, while β-cells failed to meet the increased insulin demand. |
2021-12-02 |
2023-08-13 |
mouse |
Yumeng Peng, Qiang Zeng, Luming Wan, Enhao Ma, Huilong Li, Xiaopan Yang, Yanhong Zhang, Linfei Huang, Haotian Lin, Jiangyue Feng, Yixin Xu, Jingfei Li, Muyi Liu, Jing Liu, Changqin Lin, Zhiwei Sun, Gong Cheng, Xuemiao Zhang, Jialong Liu, Dongrui Li, Meng Wei, Yunhai Mo, Xuetao Mu, Xiaowei Deng, Dandan Zhang, Siqing Dong, Hanqing Huang, Yi Fang, Qi Gao, Xiaoli Yang, Feixiang Wu, Hui Zhong, Congwen We. GP73 is a TBC-domain Rab GTPase-activating protein contributing to the pathogenesis of non-alcoholic fatty liver disease without obesity. Nature communications. vol 12. issue 1. 2021-12-02. PMID:34853313. |
upon regular-diet feeding, liver-gp73-high mice display non-obese nafld phenotype, characterized by reduced body weight, intrahepatic lipid accumulation, and gradual insulin resistance development, none of which can be recapitulated in liver-gap inactive gp73-high mice. |
2021-12-02 |
2023-08-13 |
mouse |
Yuan Chen, Mulan He, Martina M L Lei, Wendy K W Ko, Chengyuan Lin, Zhaoxiang Bian, Anderson O L Won. Mouse Spexin: (III) Differential Regulation by Glucose and Insulin in Glandular Stomach and Functional Implication in Feeding Control. Frontiers in endocrinology. vol 12. 2021-12-01. PMID:34025589. |
mouse spexin: (iii) differential regulation by glucose and insulin in glandular stomach and functional implication in feeding control. |
2021-12-01 |
2023-08-13 |
mouse |
Victor G L Fonseca, Bruno I Cappellozza, Osvaldo A de Sousa, Manuella Sagawa, Bruna Rett, Mário L Chizzotti, Reinaldo F Cook. Strategic administration of an appeasing substance to improve performance and physiological responses of Bos indicus feedlot cattle. Journal of animal science. vol 99. issue 11. 2021-12-01. PMID:34734258. |
bulls administered bas prior to loading and at feedlot entry had less (p ≤ 0.05) mean serum cortisol concentrations across the 108-d feeding period (loading × feedlot entry interaction; p = 0.10) and greater (p ≤ 0.05) serum insulin concentration on day 60 (loading × feedlot entry × day interaction; p = 0.05). |
2021-12-01 |
2023-08-13 |
cattle |
Fucheng Guo, Rendalai Si, Quanyun Li, Le Hai, Li Yi, Jing He, Liang Ming, Rimutu J. Reversible insulin resistance helps Bactrian camels survive fasting. Scientific reports. vol 11. issue 1. 2021-11-30. PMID:34552154. |
through the comparison of insulin signalling pathway genes in different tissues in different eating periods (feeding, fasting and recovery feeding), it was found that irs1, pik3cb, pik3r1 and slc2a4 expression was significantly downregulated in the fore hump and hind hump during the fasting period. |
2021-11-30 |
2023-08-13 |
Not clear |
Ying Liu, Yu-Chen Xu, Yu-Gui Cui, Shi-Wen Jiang, Fei-Yang Diao, Jia-Yin Liu, Xiang M. Androgen excess increases food intake in a rat polycystic ovary syndrome model by down-regulating hypothalamus insulin and leptin signaling pathways preceding weight gain. Neuroendocrinology. 2021-11-30. PMID:34847556. |
androgen excess increases food intake in a rat polycystic ovary syndrome model by down-regulating hypothalamus insulin and leptin signaling pathways preceding weight gain. |
2021-11-30 |
2023-08-13 |
rat |
Ying Liu, Yu-Chen Xu, Yu-Gui Cui, Shi-Wen Jiang, Fei-Yang Diao, Jia-Yin Liu, Xiang M. Androgen excess increases food intake in a rat polycystic ovary syndrome model by down-regulating hypothalamus insulin and leptin signaling pathways preceding weight gain. Neuroendocrinology. 2021-11-30. PMID:34847556. |
in addition, the hypothalamic sensitivity to insulin and leptin was also impaired in the dht-induced rats before obesity and with restricted food intake. |
2021-11-30 |
2023-08-13 |
rat |
Ying Liu, Yu-Chen Xu, Yu-Gui Cui, Shi-Wen Jiang, Fei-Yang Diao, Jia-Yin Liu, Xiang M. Androgen excess increases food intake in a rat polycystic ovary syndrome model by down-regulating hypothalamus insulin and leptin signaling pathways preceding weight gain. Neuroendocrinology. 2021-11-30. PMID:34847556. |
conclusions androgen excess increased food intake in rats and promoted obesity by down-regulating insulin and leptin signaling in the hypothalamus, most likely by suppressing leptin levels in the csf. |
2021-11-30 |
2023-08-13 |
rat |
Mariami Jasaszwili, Tatiana Wojciechowicz, Mathias Z Strowski, Krzysztof W Nowak, Marek Skrzypsk. The effects of neuronostatin on proliferation and differentiation of rat primary preadipocytes and 3T3-L1 cells. Biochimica et biophysica acta. Molecular and cell biology of lipids. vol 1866. issue 11. 2021-11-29. PMID:34332074. |
there is evidence indicating that neuronostatin modulates energy homeostasis by suppressing food intake and insulin secretion, while stimulating glucagon secretion. |
2021-11-29 |
2023-08-13 |
rat |