| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Srinivasan, B Viswanad, Lydia Asrat, C L Kaul, P Ramara. Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening. Pharmacological research. vol 52. issue 4. 2006-04-14. PMID:15979893. |
hyperinsulinemia together with reduced glucose disappearance rate (k-value) suggested that the feeding of hfd-induced insulin resistance in rats. |
2006-04-14 |
2023-08-12 |
human |
| Marcelino Hernández-Valenci. [Basic aspects for the control of gestational diabetes]. Revista medica del Instituto Mexicano del Seguro Social. vol 43. issue 5. 2006-04-11. PMID:16392197. |
glucose posprandial determinations two hours after food intake is advisable in patients that need insulin administration, which avoids determinations four times a day. |
2006-04-11 |
2023-08-12 |
Not clear |
| Sylvie Franckhauser, Sergio Muñoz, Ivet Elias, Tura Ferre, Fatima Bosc. Adipose overexpression of phosphoenolpyruvate carboxykinase leads to high susceptibility to diet-induced insulin resistance and obesity. Diabetes. vol 55. issue 2. 2006-03-23. PMID:16443757. |
these results indicate that increased pepck expression in the presence of high-fat feeding may have deleterious effects and lead to severe insulin resistance and type 2 diabetes. |
2006-03-23 |
2023-08-12 |
mouse |
| Helga Davidowa, Andreas Plageman. Action of prolactin, prolactin-releasing peptide and orexins on hypothalamic neurons of adult, early postnatally overfed rats. Neuro endocrinology letters. vol 26. issue 5. 2006-03-17. PMID:16264391. |
hypothalamic neurons of rats overweight due to early postnatal overfeeding (sl) differ from those of control rats in their responses to feeding relevant hormones like leptin or insulin. |
2006-03-17 |
2023-08-12 |
rat |
| Jeffrey R Bernard, Donald W Reeder, Henry J Herr, Donato A Rivas, Ben B Yaspelki. High-fat feeding effects on components of the CAP/Cbl signaling cascade in Sprague-Dawley rat skeletal muscle. Metabolism: clinical and experimental. vol 55. issue 2. 2006-03-17. PMID:16423627. |
the aim of this investigation was to determine whether the cap (cbl-associated protein)/cbl signaling cascade is present and responsive to insulin in skeletal muscle and if high-fat feeding impairs insulin-stimulated activation of this signaling cascade. |
2006-03-17 |
2023-08-12 |
rat |
| Jeffrey R Bernard, Donald W Reeder, Henry J Herr, Donato A Rivas, Ben B Yaspelki. High-fat feeding effects on components of the CAP/Cbl signaling cascade in Sprague-Dawley rat skeletal muscle. Metabolism: clinical and experimental. vol 55. issue 2. 2006-03-17. PMID:16423627. |
in plasma membrane fractions, neither the high-fat diet nor insulin altered the insulin receptor beta subunit (ir-beta), aps (adaptor protein containing ph and sh2 domains), c-cbl, or tc10 protein concentration, but high-fat feeding did decrease cap protein concentration. |
2006-03-17 |
2023-08-12 |
rat |
| Jeffrey R Bernard, Donald W Reeder, Henry J Herr, Donato A Rivas, Ben B Yaspelki. High-fat feeding effects on components of the CAP/Cbl signaling cascade in Sprague-Dawley rat skeletal muscle. Metabolism: clinical and experimental. vol 55. issue 2. 2006-03-17. PMID:16423627. |
these findings suggest that the cap/cbl signaling cascade is present in skeletal muscle, activated by insulin, and impaired by high-fat feeding. |
2006-03-17 |
2023-08-12 |
rat |
| E Rabelo, R L Rezende, S J Bertics, R R Grumme. Effects of pre- and postfresh transition diets varying in dietary energy density on metabolic status of periparturient dairy cows. Journal of dairy science. vol 88. issue 12. 2006-03-16. PMID:16291629. |
cows fed h had higher concentrations of plasma glucose and insulin, but similar plasma nefa during the postpartum period compared with cows fed l. plasma concentrations of beta-hydroxybutyrate (bhba) and liver tg content on d 21 were 46 and 30% lower, respectively, for cows fed h compared with cows fed l. interactions between prepartum and postpartum treatments indicated that negative effects of delaying higher concentrate feeding until d 21 postpartum can be partially offset by increasing concentrate in the diet before calving. |
2006-03-16 |
2023-08-12 |
Not clear |
| Christopher Lipina, Xu Huang, David Finlay, Edward J McManus, Dario R Alessi, Calum Sutherlan. Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3. The Biochemical journal. vol 392. issue Pt 3. 2006-03-13. PMID:16176184. |
interestingly, insulin injection of wild-type mice, which activates pkb (protein kinase b) and inhibits gsk3 to a greater degree than feeding (50% versus 25%), does not repress these genes. |
2006-03-13 |
2023-08-12 |
mouse |
| Katja Kannisto, Alexander Chibalin, Björn Glinghammar, Juleen R Zierath, Anders Hamsten, Ewa Ehrenbor. Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise. International journal of molecular medicine. vol 17. issue 1. 2006-03-10. PMID:16328010. |
as skeletal muscle is an important site for insulin action and acts as a significant sensor for life-style-induced influences in whole-body energy metabolism, we investigated the expression of pparalpha, -delta and -gamma in rat skeletal muscle in response to exercise after four- and twelve-weeks of high-fat feeding, respectively. |
2006-03-10 |
2023-08-12 |
rat |
| Aimee M Powelka, Asha Seth, Joseph V Virbasius, Evangelos Kiskinis, Sarah M Nicoloro, Adilson Guilherme, Xiaoqing Tang, Juerg Straubhaar, Andrew D Cherniack, Malcolm G Parker, Michael P Czec. Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. The Journal of clinical investigation. vol 116. issue 1. 2006-03-02. PMID:16374519. |
rip140-null mice, previously reported to resist weight gain on a high-fat diet, are shown here to display enhanced glucose tolerance and enhanced responsiveness to insulin compared with matched wild-type mice upon high-fat feeding. |
2006-03-02 |
2023-08-12 |
mouse |
| Effiong E Otukonyong, Michael G Dube, Rita Torto, Pushpa S Kalra, Satya P Kalr. Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight. Peptides. vol 26. issue 12. 2006-02-28. PMID:15936848. |
central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight. |
2006-02-28 |
2023-08-12 |
rat |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
the hypothalamic circuitry, apart from its impact on food intake, modulates insulin sensitivity to adapt metabolic conditions in the face of environmental fluctuations in nutrient availability. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
the purpose of the present study was to investigate the effects of 2 weeks high fat feeding in wildtype mice on (1) insulin sensitivity and triglyceride accumulation in liver and muscle in relation to (2) mrna expression levels of neuropeptide y (npy), agouti-related protein (agrp), pro-opiomelanocortin (pomc), and cocaine- and amphetamine-regulated transcript (cart) in the hypothalamus. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
two weeks of high fat feeding induced hepatic insulin resistance in the presence of increased hepatic triglyceride accumulation. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
in muscle, however, 2 weeks of high fat feeding did not result in changes in insulin sensitivity or in triglyceride content. |
2006-02-28 |
2023-08-12 |
mouse |
| A C Heijboer, P J Voshol, E Donga, C G van Eden, L M Havekes, J A Romijn, H Pijl, E P M Corssmi. High fat diet induced hepatic insulin resistance is not related to changes in hypothalamic mRNA expression of NPY, AgRP, POMC and CART in mice. Peptides. vol 26. issue 12. 2006-02-28. PMID:15979206. |
this study shows that 2 weeks of high fat feeding in mice does not affect mrna expression levels of npy, agrp, pomc or cart, in the whole hypothalamus, despite induction of hepatic, but not peripheral, insulin resistance. |
2006-02-28 |
2023-08-12 |
mouse |
| Jie Xu, Adam B Keeton, John L Franklin, Xin Li, Derwei Y Venable, Stuart J Frank, Joseph L Messin. Insulin enhances growth hormone induction of the MEK/ERK signaling pathway. The Journal of biological chemistry. vol 281. issue 2. 2006-02-28. PMID:16272159. |
we hypothesized that short-term insulin, similar to the fluctuations that occur following feeding, affects gh-induced post-ghr signaling. |
2006-02-28 |
2023-08-12 |
rat |
| V Makoundou, A Gola. [New obesity and metabolic syndrome treatment: rimonabant]. Revue medicale suisse. vol 2. issue 47. 2006-02-28. PMID:16465944. |
hyperstimulation of the cbi receptors lead to an increase of food intake, but also to an increase of lipogenesis, decrease of adiponectin and increase of insulin resistance. |
2006-02-28 |
2023-08-12 |
Not clear |
| Gregory J Morton, Richard W Gelling, Kevin D Niswender, Christopher D Morrison, Christopher J Rhodes, Michael W Schwart. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell metabolism. vol 2. issue 6. 2006-02-27. PMID:16330326. |
this intervention markedly improved insulin sensitivity in genetically obese, leptin-receptor-deficient koletsky (fa(k)/fa(k)) rats via a mechanism that was not dependent on reduced food intake but was attenuated by approximately 44% by third-ventricular infusion of the pi3k inhibitor ly294002. |
2006-02-27 |
2023-08-12 |
rat |