| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonio J Ruiz-Alcaraz, Hui-Kang Liu, Daniel J Cuthbertson, Edward J McManus, Simeen Akhtar, Christopher Lipina, Andrew D Morris, John R Petrie, Hari S Hundal, Calum Sutherlan. A novel regulation of IRS1 (insulin receptor substrate-1) expression following short term insulin administration. The Biochemical journal. vol 392. issue Pt 2. 2006-02-23. PMID:16128672. |
similarly, transient induction of irs1 (3-fold) in the liver or muscle of rodents occurs following feeding or insulin injection respectively. |
2006-02-23 |
2023-08-12 |
human |
| J Ducob. [The endocannabinoid system and the regulation of the metabolism]. Revue medicale de Bruxelles. vol 26. issue 3. 2006-02-21. PMID:16038140. |
cb1 blockade by a specific inhibitor (rimonabant) decreases food intake and weight in animal studies and increases adiponectin and insulin sensitivity. |
2006-02-21 |
2023-08-12 |
Not clear |
| F Yakubu, D Lin, J C Peters, G W Reed, J O Hil. Insulin action in rats is influenced by amount and composition of dietary fat. Obesity research. vol 1. issue 6. 2006-02-06. PMID:16353334. |
six months of feeding a high fat (hf) diet led to obesity and impaired insulin action (determined by a euglycemic-hyperinsulinemic clamp), neither of which were reversed by a subsequent 6 months of feeding a low fat (lf) diet. |
2006-02-06 |
2023-08-12 |
rat |
| F Yakubu, D Lin, J C Peters, G W Reed, J O Hil. Insulin action in rats is influenced by amount and composition of dietary fat. Obesity research. vol 1. issue 6. 2006-02-06. PMID:16353334. |
six months of feeding a low fat diet led to only a slight decline in insulin action, with no difference due to type of dietary fat. |
2006-02-06 |
2023-08-12 |
rat |
| F Yakubu, D Lin, J C Peters, G W Reed, J O Hil. Insulin action in rats is influenced by amount and composition of dietary fat. Obesity research. vol 1. issue 6. 2006-02-06. PMID:16353334. |
both feeding a high fat diet and feeding a low fat saturated diet accelerated the impairment in insulin action relative to rats fed a low fat polyunsaturated fat diet. |
2006-02-06 |
2023-08-12 |
rat |
| T Wolden-Hanson, G A Davis, S T Baum, J W Kemnit. Insulin levels, physical activity, and urinary catecholamine excretion of obese and non-obese rhesus monkeys. Obesity research. vol 1. issue 1. 2006-02-06. PMID:16353346. |
urinary excretion of c-peptide and catecholamines was measured during successive 2-day periods of ad libitum feeding, food deprivation, and refeeding in order to examine potential differences between groups in sympathoadrenal activity and their relationship to insulin secretion. |
2006-02-06 |
2023-08-12 |
monkey |
| Roberta Giordano, Andreea Picu, Fabio Broglio, Lorenza Bonelli, Matteo Baldi, Rita Berardelli, Ezio Ghigo, Emanuela Arva. Ghrelin, hypothalamus-pituitary-adrenal (HPA) axis and Cushing's syndrome. Pituitary. vol 7. issue 4. 2006-02-03. PMID:16132204. |
ghrelin secretion is mainly regulated by metabolic signals, namely inhibited by feeding, glucose and insulin while stimulated by energy restriction. |
2006-02-03 |
2023-08-12 |
human |
| Ghafoorunissa, Ahamed Ibrahim, Laxmi Rajkumar, Vani Achary. Dietary (n-3) long chain polyunsaturated fatty acids prevent sucrose-induced insulin resistance in rats. The Journal of nutrition. vol 135. issue 11. 2006-02-03. PMID:16253960. |
compared with starch (st-210), sucrose feeding (su-210) significantly increased the plasma insulin and triglyceride concentrations and the plasma insulin area under the curve (auc) in response to an oral glucose load. |
2006-02-03 |
2023-08-12 |
rat |
| Kristen E La Flamme, Gopal Mor, Dawei Gong, Thomas La Tempa, Vincent A Fusaro, Craig A Grimes, Tejal A Desa. Nanoporous alumina capsules for cellular macroencapsulation: transport and biocompatibility. Diabetes technology & therapeutics. vol 7. issue 5. 2006-02-01. PMID:16241869. |
daily injections, however, cannot match the physiological biphasic behavior of normal insulin release, nor can they precisely meet the demands of food intake, exercise, and stress. |
2006-02-01 |
2023-08-12 |
human |
| David A D'Alessio, Torsten P Vah. Utilizing the GLP-1 signaling system to treat diabetes: sorting through the pharmacologic approaches. Current diabetes reports. vol 5. issue 5. 2006-01-26. PMID:16188169. |
glucagon-like peptide-1 (glp-1) is an intestinal hormone that promotes glucose homeostasis through the regulation of insulin and glucagon secretion, gastric emptying, and food intake. |
2006-01-26 |
2023-08-12 |
Not clear |
| P G Quinn, D Yeagle. Insulin regulation of PEPCK gene expression: a model for rapid and reversible modulation. Current drug targets. Immune, endocrine and metabolic disorders. vol 5. issue 4. 2006-01-20. PMID:16375695. |
normally, pepck expression is induced by glucagon, catecholamines and glucocorticoids during periods of fasting and in response to stress, but is dominantly inhibited by glucose-induced increases in insulin secretion upon feeding. |
2006-01-20 |
2023-08-12 |
Not clear |
| Andreas Plageman. Perinatal programming and functional teratogenesis: impact on body weight regulation and obesity. Physiology & behavior. vol 86. issue 5. 2006-01-17. PMID:16280141. |
in rats, endogenous hyperinsulinism, as well as peripheral or only intrahypothalamic insulin treatment during perinatal development, may lead to 'malprogramming' of neuroendocrine systems regulating body weight, food intake and metabolism. |
2006-01-17 |
2023-08-12 |
rat |
| A T Anitha Nandhini, V Thirunavukkarasu, C V Anuradh. Taurine modifies insulin signaling enzymes in the fructose-fed insulin resistant rats. Diabetes & metabolism. vol 31. issue 4 Pt 1. 2006-01-12. PMID:16369195. |
high fructose feeding induces insulin resistance and hyperinsulinemia in rats. |
2006-01-12 |
2023-08-12 |
rat |
| Susan K Raatz, Carolyn J Torkelson, J Bruce Redmon, Kristell P Reck, Christine A Kwong, Joyce E Swanson, Chengcheng Liu, William Thomas, John P Bantl. Reduced glycemic index and glycemic load diets do not increase the effects of energy restriction on weight loss and insulin sensitivity in obese men and women. The Journal of nutrition. vol 135. issue 10. 2006-01-11. PMID:16177201. |
all groups improved in insulin sensitivity at the end of the feeding phase of the study. |
2006-01-11 |
2023-08-12 |
human |
| Tetsuo Tsubone, Takayuki Masaki, Isao Katsuragi, Katsuhiro Tanaka, Tetsuya Kakuma, Hironobu Yoshimats. Leptin downregulates ghrelin levels in streptozotocin-induced diabetic mice. American journal of physiology. Regulatory, integrative and comparative physiology. vol 289. issue 6. 2006-01-10. PMID:16109802. |
these results indicate that leptin treatment partially reverses elevated plasma ghrelin levels in stz-dm mice independent of food intake and insulin, and suggest that hypoleptinemia in stz-dm mice upregulates ghrelin. |
2006-01-10 |
2023-08-12 |
mouse |
| Georgia Frangioudakis, Ji-Ming Ye, Gregory J Coone. Both saturated and n-6 polyunsaturated fat diets reduce phosphorylation of insulin receptor substrate-1 and protein kinase B in muscle during the initial stages of in vivo insulin stimulation. Endocrinology. vol 146. issue 12. 2006-01-05. PMID:16150913. |
these results demonstrate that under conditions of increased insulin, similar to those used to assess insulin action in vivo, chronic high-fat feeding impairs insulin signal transduction related to glucose metabolism at the level of irs-1 tyr612 and pkb ser473 and that these effects are independent of the type of fat used in the high-fat diet. |
2006-01-05 |
2023-08-12 |
rat |
| V Kairamkonda, A Deorukhkar, R Coombs, R Fraser, T Maye. Amylin peptide levels are raised in infants of diabetic mothers. Archives of disease in childhood. vol 90. issue 12. 2006-01-05. PMID:16174639. |
amylin is a novel 37 amino acid peptide hormone that is co-secreted with insulin from the pancreas in response to food intake. |
2006-01-05 |
2023-08-12 |
Not clear |
| Woo Je Lee, Eun Hee Koh, Jong Chul Won, Min-Seon Kim, Joong-Yeol Park, Ki-Up Le. Obesity: the role of hypothalamic AMP-activated protein kinase in body weight regulation. The international journal of biochemistry & cell biology. vol 37. issue 11. 2005-12-29. PMID:16085448. |
leptin, insulin, glucose and alpha-lipoic acid have been shown to reduce food intake by lowering hypothalamic amp-activated protein kinase activity, whereas ghrelin and glucose depletion increase food intake by increasing hypothalamic amp-activated protein kinase activity. |
2005-12-29 |
2023-08-12 |
Not clear |
| E Herrera, I López-Soldado, M Limones, E Amusquivar, M P Ramo. Experimental models for studying perinatal lipid metabolism. Long-term effects of perinatal undernutrition. Advances in experimental medicine and biology. vol 569. 2005-12-22. PMID:16137112. |
results show that the decreased food intake caused by a n-3 fatty acid-rich diet rather than the change in milk composition during suckling was responsible for the reduced pancreatic glucose responsiveness to insulin release at 16 weeks of age. |
2005-12-22 |
2023-08-12 |
rat |
| Becky M Sebastian, Laura E Nag. Decreased insulin-dependent glucose transport by chronic ethanol feeding is associated with dysregulation of the Cbl/TC10 pathway in rat adipocytes. American journal of physiology. Endocrinology and metabolism. vol 289. issue 6. 2005-12-21. PMID:16105861. |
furthermore, chronic ethanol feeding increased the amount of activated tc10 and filamentous actin in adipocytes at baseline and abrogated the ability of insulin to further activate tc10 or polymerize actin. |
2005-12-21 |
2023-08-12 |
rat |