| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Ramesh, K V Pugalend. Antihyperlipidemic and antidiabetic effects of umbelliferone in streptozotocin diabetic rats. The Yale journal of biology and medicine. vol 78. issue 4. 2006-06-15. PMID:16720013. |
diabetic rats had increased plasma glucose and decreased insulin, total proteins (tp), and albumin in addition to decreased food intake and body weight. |
2006-06-15 |
2023-08-12 |
rat |
| B Ramesh, K V Pugalend. Antihyperlipidemic and antidiabetic effects of umbelliferone in streptozotocin diabetic rats. The Yale journal of biology and medicine. vol 78. issue 4. 2006-06-15. PMID:16720013. |
treatment with umb decreased plasma glucose and increased insulin, tp, and albumin apart from food intake and body weight. |
2006-06-15 |
2023-08-12 |
rat |
| Mark F McCart. PKC-mediated modulation of L-type calcium channels may contribute to fat-induced insulin resistance. Medical hypotheses. vol 66. issue 4. 2006-06-14. PMID:16307847. |
in fat-fed insulin resistant rats, pre-treatment with a drug that selectively chelates intracellular calcium eliminates about half of the decrement in insulin-stimulated glucose uptake induced by fat feeding; since this chelator does not influence the insulin sensitivity of chow-fed rats, it is reasonable to suspect that fat feeding boosts [ca2+]i in skeletal muscle, and that this effect is partially responsible for the associated reduction in insulin sensitivity. |
2006-06-14 |
2023-08-12 |
human |
| D K Arulmozhi, B Porth. GLP-1 based therapy for type 2 diabetes. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 28. issue 1-2. 2006-06-14. PMID:16488579. |
glp-1 glucoregulatory actions include glucose-dependent enhancement of insulin secretion, inhibition of glucagon secretion, slowing of gastric emptying and reduction of food intake. |
2006-06-14 |
2023-08-12 |
Not clear |
| G Fatati, S Coacciol. [Artificial nutrition in the patient with hyperglycemia]. La Clinica terapeutica. vol 157. issue 1. 2006-06-06. PMID:16669545. |
patients with newly diagnosed hyperglycemia had a significantly higher mortality rate and a lower functional outcome than patients with a known history of diabetes or normoglycemia intensive insulin treatment to normalize blood glucose during feeding has been shown to improve morbidity and mortality in patients in intensive care. |
2006-06-06 |
2023-08-12 |
Not clear |
| Taryne Chong, Mark Naples, Lisa Federico, Denise Taylor, Graham J Smith, Raphael C Cheung, Khosrow Adel. Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia. Atherosclerosis. vol 185. issue 1. 2006-05-30. PMID:16002078. |
fructose feeding for a 2-week period induced insulin resistance and a significant increase in hepatic secretion of vldl. |
2006-05-30 |
2023-08-12 |
Not clear |
| Matthew J Watt, Andrea Hevener, Graeme I Lancaster, Mark A Febbrai. Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues. Endocrinology. vol 147. issue 5. 2006-05-23. PMID:16396984. |
to avoid confounding effects of long-term high-fat feeding or genetic manipulation on whole-body insulin sensitivity, we performed a 2-h intralipid infusion (20% heparinized intralipid) with or without recombinant cntf pretreatment (axokine 0.3 mg/kg), followed by a 2-h hyperinsulinemic-euglycemic clamp (12 mu/kg.min) in fasted, male wistar rats. |
2006-05-23 |
2023-08-12 |
rat |
| S Rajamani, R Suganthi, M K Ravichandran, C V Anuradh. Food seasoning spices mixture improves glucose metabolism and lipid profile in fructose-fed hyperinsulinemic rats. Journal of medicinal food. vol 8. issue 4. 2006-05-22. PMID:16379562. |
fructose feeding has been shown to induce insulin resistance in rats, associated with hyperinsulinemia, hyperglycemia, and hypertriglyceridemia. |
2006-05-22 |
2023-08-12 |
rat |
| Naohito Nishii, Masaki Takasu, Yasunori Ohba, Sadatoshi Maeda, Katsuya Kitoh, Yoshihiko Ohtsuka, Tsutomu Honjo, Masayuki Saito, Hitoshi Kitagaw. Effects of administration of glucocorticoids and feeding status on plasma leptin concentrations in dogs. American journal of veterinary research. vol 67. issue 2. 2006-05-05. PMID:16454631. |
to investigate effects of short- and long- term administration of glucocorticoids, feeding status, and serum concentrations of insulin and cortisol on plasma leptin concentrations in dogs. |
2006-05-05 |
2023-08-12 |
Not clear |
| Akihiko Wada, Hiroki Yokoo, Toshihiko Yanagita, Hideyuki Kobayash. New twist on neuronal insulin receptor signaling in health, disease, and therapeutics. Journal of pharmacological sciences. vol 99. issue 2. 2006-05-03. PMID:16210778. |
in the hypothalamus, insulin regulates food intake, body weight, peripheral fat deposition, hepatic gluconeogenesis, reproductive endocrine axis, and compensatory secretion of counter-regulatory hormones to hypoglycemia. |
2006-05-03 |
2023-08-12 |
Not clear |
| Thomas C Vary, Christopher J Lync. Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation. American journal of physiology. Endocrinology and metabolism. vol 290. issue 4. 2006-05-02. PMID:16263769. |
feeding promotes protein accretion in skeletal muscle through a stimulation of the mrna translation initiation phase of protein synthesis either secondarily to nutrient-induced rises in insulin or owing to direct effects of nutrients themselves. |
2006-05-02 |
2023-08-12 |
rat |
| Jia-Guo Liu, Hong-Jin Zhao, Yan-Juan Liu, Xiao-Long Wan. Effect of selenium-enriched malt on hepatocarcinogenesis, paraneoplastic syndrome and the hormones regulating blood glucose in rats treated by diethylnitrosamine. Life sciences. vol 78. issue 20. 2006-05-02. PMID:16266726. |
the results indicated that se-enriched malt showed a better chemopreventive efficiency in decreasing the number of hepatoma nodules, relative liver weight and the contents of afp, ggt, igf-ii, alt, alp and tbil in the plasma, and delaying the descent of hormones in the serum, names as insulin, glucagons, t(3) and t(4) than those feeding with sodium selenite. |
2006-05-02 |
2023-08-12 |
rat |
| M Takenaga, Y Yamaguchi, Y Ogawa, A Kitagawa, S Kawai, Y Mizushima, R Igarashi, M Namae, K Komed. Administration of optimum sustained-insulin release PLGA microcapsules to spontaneous diabetes-prone BB/Wor//Tky rats. Drug delivery. vol 13. issue 2. 2006-05-02. PMID:16423804. |
every 2 weeks subcutaneous administration made their blood glucose level depend on the insulin release and food intake. |
2006-05-02 |
2023-08-12 |
rat |
| Bernard Thoren. [Gluco-incretin hormones in insulin secretion]. Medecine sciences : M/S. vol 21 Spec No. 2006-05-02. PMID:16598904. |
although the beta cell secretary response is mainly controlled by blood glucose levels, gut hormones secreted in response to food intake have an important role in potentiating glucose-stimulated insulin secretion. |
2006-05-02 |
2023-08-12 |
Not clear |
| Ramu Suganthi, Shanmuganathan Rajamani, Mambakkam Katchapeswaran Ravichandran, Carani Venkatraman Anuradh. Preventive action of food seasoning spices mixture on fructose-induced lipid abnormalities. Asia Pacific journal of clinical nutrition. vol 14. issue 4. 2006-05-01. PMID:16326650. |
high fructose feeding in rats induces insulin resistance, hyperinsulinemia, hyperglycemia and dyslipidemia. |
2006-05-01 |
2023-08-12 |
rat |
| Tetsuya Yamada, Hideki Katagiri, Yasushi Ishigaki, Takehide Ogihara, Junta Imai, Kenji Uno, Yutaka Hasegawa, Junhong Gao, Hisamitsu Ishihara, Akira Niijima, Hiroyuki Mano, Hiroyuki Aburatani, Tomoichiro Asano, Yoshitomo Ok. Signals from intra-abdominal fat modulate insulin and leptin sensitivity through different mechanisms: neuronal involvement in food-intake regulation. Cell metabolism. vol 3. issue 3. 2006-05-01. PMID:16517409. |
in contrast, ucp1 expression in epi of leptin-receptor mutant mice did not alter food intake, though it significantly decreased blood glucose and insulin levels. |
2006-05-01 |
2023-08-12 |
mouse |
| Bernard Beck, Rouba Kozak, Kim M Moar, Julian G Merce. Hypothalamic orexigenic peptides are overexpressed in young Long-Evans rats after early life exposure to fat-rich diets. Biochemical and biophysical research communications. vol 342. issue 2. 2006-04-28. PMID:16487482. |
to establish the influence of the macronutrient type on feeding regulatory mechanisms and more particularly on stimulatory pathways (galanin and orexins), we fed female rats on either a high-carbohydrate (hc), a high-fat (hf), or a well-balanced control diet during gestation and lactation, and measured peptide expression in the hypothalamus and important hormones (leptin, insulin) in their pups at weaning. |
2006-04-28 |
2023-08-12 |
rat |
| Edurne Simón, M Teresa Macarulla, Itziar Churruca, Alfredo Fernández-Quintela, María P Portill. trans-10,cis-12 conjugated linoleic acid prevents adiposity but not insulin resistance induced by an atherogenic diet in hamsters. The Journal of nutritional biochemistry. vol 17. issue 2. 2006-04-21. PMID:16111872. |
atherogenic feeding also led to significantly higher serum concentrations of glucose, insulin, ffas, as well as greater homa-ir values. |
2006-04-21 |
2023-08-12 |
Not clear |
| Edurne Simón, M Teresa Macarulla, Itziar Churruca, Alfredo Fernández-Quintela, María P Portill. trans-10,cis-12 conjugated linoleic acid prevents adiposity but not insulin resistance induced by an atherogenic diet in hamsters. The Journal of nutritional biochemistry. vol 17. issue 2. 2006-04-21. PMID:16111872. |
in summary, although the addition of trans-10,cis-12 cla to an atherogenic diet reduces fat accumulation, it does not improve the impairment of insulin action associated with this feeding. |
2006-04-21 |
2023-08-12 |
Not clear |
| Mikael Bjursell, Anna-Karin Gerdin, Karolina Ploj, David Svensson, Lennart Svensson, Jan Oscarsson, Michael Snaith, Jan Törnell, Mohammad Bohlooly-. Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight. Diabetes. vol 55. issue 3. 2006-04-19. PMID:16505236. |
in mchr1 knockout ob/ob mice an oral glucose load resulted in a lower blood glucose response and markedly lower insulin levels compared with the ob/ob mice despite no differences in body weight, food intake, or energy expenditure. |
2006-04-19 |
2023-08-12 |
mouse |