| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinghong Shi, Jianqun Yan, Qi Lei, Junjie Zhao, Ke Chen, Dejun Yang, Xiaolin Zhao, Yuan Zhan. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain research. vol 1247. 2009-02-19. PMID:18955035. |
the hypothalamus is one of the areas in the brain linked to the control of food intake and energy expenditure. |
2009-02-19 |
2023-08-12 |
rat |
| Jinghong Shi, Jianqun Yan, Qi Lei, Junjie Zhao, Ke Chen, Dejun Yang, Xiaolin Zhao, Yuan Zhan. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain research. vol 1247. 2009-02-19. PMID:18955035. |
we investigated the effects of evo on food intake, body weight, the mrna expression and peptide level of feeding-related peptides in the hypothalamus, in male rats. |
2009-02-19 |
2023-08-12 |
rat |
| Jinghong Shi, Jianqun Yan, Qi Lei, Junjie Zhao, Ke Chen, Dejun Yang, Xiaolin Zhao, Yuan Zhan. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain research. vol 1247. 2009-02-19. PMID:18955035. |
our results show that intragastric administration of evo (40 mg/kg) decreased rate of food intake and body weight increase following rat growth, reduced orexigenic neuropeptide y (npy) and agouti-gene related protein (agrp) mrna levels and npy peptide level in the arcuate nucleus (arc) of the hypothalamus, but it increases the circulating level of leptin. |
2009-02-19 |
2023-08-12 |
rat |
| Jinghong Shi, Jianqun Yan, Qi Lei, Junjie Zhao, Ke Chen, Dejun Yang, Xiaolin Zhao, Yuan Zhan. Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats. Brain research. vol 1247. 2009-02-19. PMID:18955035. |
these data suggest that evo decreases food intake, and therefore body weight, partly by down-regulating npy and agrp mrna expression and peptide expression in the arc of the hypothalamus. |
2009-02-19 |
2023-08-12 |
rat |
| Gareth Leng, Tatsushi Onaka, Celine Caquineau, Nancy Sabatier, Vicky A Tobin, Yuki Takayanag. Oxytocin and appetite. Progress in brain research. vol 170. 2009-02-13. PMID:18655879. |
oxytocin has potent central effects on feeding behaviour, as well as on social and sexual behaviours, and one likely substrate for its anorectic effect is the ventromedial nucleus of the hypothalamus. |
2009-02-13 |
2023-08-12 |
Not clear |
| Daniel D Lam, Ligang Zhou, Andreas Vegge, Philip Y Xiu, Britt T Christensen, Mayowa A Osundiji, Chen-yu Yueh, Mark L Evans, Lora K Heisle. Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia. Behavioural brain research. vol 196. issue 1. 2009-02-03. PMID:18762217. |
nts catecholaminergic neurons relay visceral gastrointestinal signals to both the lateral hypothalamus (lha) and paraventricular nucleus of the hypothalamus (pvh), where these signals are integrated into autonomic and hormonal responses regulating food intake. |
2009-02-03 |
2023-08-12 |
rat |
| M Dallaporta, E Pecchi, J Pio, A Jean, K C Horner, J D Troade. Expression of leptin receptor by glial cells of the nucleus tractus solitarius: possible involvement in energy homeostasis. Journal of neuroendocrinology. vol 21. issue 1. 2009-02-03. PMID:19094094. |
leptin, an adipocyte-derived hormone, regulates food intake and body weight by acting principally on the hypothalamus, which displays the highest expression of leptin receptor (ob-r). |
2009-02-03 |
2023-08-12 |
Not clear |
| Melissa J S Chee, William F Colmer. Y eat? Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18662858. |
feeding behavior is tightly regulated by peptidergic transmission within the hypothalamus. |
2009-01-28 |
2023-08-12 |
Not clear |
| Yasuhiko Minokoshi, Tetsuya Shiuchi, Suni Lee, Atsushi Suzuki, Shiki Okamot. Role of hypothalamic AMP-kinase in food intake regulation. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725075. |
adiponectin has also been shown to increase food intake by activating ampk in the arcuate hypothalamus. |
2009-01-28 |
2023-08-12 |
Not clear |
| Yasuhiko Minokoshi, Tetsuya Shiuchi, Suni Lee, Atsushi Suzuki, Shiki Okamot. Role of hypothalamic AMP-kinase in food intake regulation. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725075. |
thus, these results suggest that food intake and nutrient metabolism are coordinately regulated by the common signaling pathway of ampk in the hypothalamus. |
2009-01-28 |
2023-08-12 |
Not clear |
| Seiji Shioda, Fumiko Takenoya, Michiko Yagi, Lihua Wang, Yasunori Hori, Haruaki Kageyam. Neural networks of several novel neuropeptides involved in feeding regulation. Nutrition (Burbank, Los Angeles County, Calif.). vol 24. issue 9. 2009-01-28. PMID:18725082. |
in the hypothalamus, cross-talk among such neurons plays a key role in determining feeding states and feeding behavior. |
2009-01-28 |
2023-08-12 |
mouse |
| Josep Maria Mercader, Juan José Lozano, Lauro Sumoy, Mara Dierssen, Joana Visa, Mònica Gratacòs, Xavier Estivil. Hypothalamus transcriptome profile suggests an anorexia-cachexia syndrome in the anx/anx mouse model. Physiological genomics. vol 35. issue 3. 2009-01-28. PMID:18812457. |
to identify new genes involved in feeding behavior and body weight regulation we performed an expression profiling in the hypothalamus of the anx/anx mice. |
2009-01-28 |
2023-08-12 |
mouse |
| Janina Briede, Mara Stivrina, Dzintra Stoldere, Brigita Vigante, Gunars Dubur. Effect of cerebrocrast on body and organ weights, food and water intake, and urine output of normal rats. Cell biochemistry and function. vol 26. issue 8. 2009-01-23. PMID:19039818. |
we can conclude that cerebrocrast may regulate food intake and body weight through glucose sensing by proopiomelanocortin (pomc) neurons, that are involved in control of glucose homeostasis, stimulation of alpha-melanocyte-stimulating hormone (alpha-msh) secretion, activation of mc4-rs and inhibition of neuropeptide y (npy) in the arc of the hypothalamus, affecting the kidney, and causing decreased urine output and water intake. |
2009-01-23 |
2023-08-12 |
rat |
| Sanghee Seo, Sunghee Ju, Hyunju Chung, Dahm Lee, Seungjoon Par. Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats. Endocrine journal. vol 55. issue 5. 2009-01-21. PMID:18506089. |
intracerebroventricular (icv) administration of glucagon-like peptide-1 (glp-1) inhibits food intake and induces c-fos expression in the hypothalamus. |
2009-01-21 |
2023-08-12 |
rat |
| T South, X-F Huan. Temporal and site-specific brain alterations in CB1 receptor binding in high fat diet-induced obesity in C57Bl/6 mice. Journal of neuroendocrinology. vol 20. issue 11. 2009-01-15. PMID:18752650. |
quantitative autoradiography revealed that binding of [3h] cp-55,940 (cb1 receptor ligand) was elevated following 3 weeks of hf feeding in areas including the medial/ventral anterior olfactory nucleus (22.1%), agranular insular cortex (24.0%) and the hypothalamus (31.5%) compared to lf controls. |
2009-01-15 |
2023-08-12 |
mouse |
| G-B Tang, J-G Cui, D-H Wan. Hypothalamic suppressor-of-cytokine-signalling 3 mRNA is elevated and pro-opiomelanocortin mRNA is reduced during pregnancy in Brandt's voles (Lasiopodomys brandtii ). Journal of neuroendocrinology. vol 20. issue 9. 2009-01-05. PMID:18638026. |
leptin acts within the hypothalamus to diminish food intake. |
2009-01-05 |
2023-08-12 |
Not clear |
| b' Lenka Malet\\xc3\\xadnsk\\xc3\\xa1, Jana Maixnerov\\xc3\\xa1, Resha Matyskov\\xc3\\xa1, Renata Haugvicov\\xc3\\xa1, Zdeno Pirn\\xc3\\xadk, Alexander Kiss, Blanka Zelezn\\xc3\\xa. Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice. BMC neuroscience. vol 9. 2008-12-19. PMID:18939974.' |
this study is based on previously found synergistic effect of leptin and cck on food intake and our hypothesis on a co-operation of the cart peptide and cck in food intake regulation and fos activation in their common targets, the nucleus tractus solitarii of the brainstem (nts), the paraventricular nucleus (pvn), and the dorsomedial nucleus (dmh) of the hypothalamus. |
2008-12-19 |
2023-08-12 |
mouse |
| Matthew P Gillum, Dongyan Zhang, Xian-Man Zhang, Derek M Erion, Rachel A Jamison, Cheolsoo Choi, Jianying Dong, Marya Shanabrough, Hillary R Duenas, David W Frederick, Jennifer J Hsiao, Tamas L Horvath, Chun Min Lo, Pat Tso, Gary W Cline, Gerald I Shulma. N-acylphosphatidylethanolamine, a gut- derived circulating factor induced by fat ingestion, inhibits food intake. Cell. vol 135. issue 5. 2008-12-19. PMID:19041747. |
furthermore, (14)c-radiolabeled nape enters the brain and is particularly concentrated in the hypothalamus, and intracerebroventricular infusions of nanomolar amounts of nape reduce food intake, collectively suggesting that its effects may be mediated through direct interactions with the central nervous system. |
2008-12-19 |
2023-08-12 |
rat |
| Beatriz Merino, Beatriz Somoza, Mariano Ruiz-Gayo, Victoria Can. Circadian rhythm drives the responsiveness of leptin-mediated hypothalamic pathway of cholecystokinin-8. Neuroscience letters. vol 442. issue 2. 2008-12-12. PMID:18638520. |
in order to further characterize the physiological relevance of the interplay between leptin and cck we have compared the effect of diurnal vs. nocturnal administration of the c-terminal octapeptide of cck (cck-8) on (i) body weight and food intake, and (ii) stat3 activation, by analyzing phosphorylated stat3 (pstat3) immunostaining within the arcuate nucleus of the hypothalamus. |
2008-12-12 |
2023-08-12 |
rat |
| Sang Dal Rhee, Yoon-Young Sung, Won Hoon Jung, Hyae Gyeong Cheo. Leptin inhibits rosiglitazone-induced adipogenesis in murine primary adipocytes. Molecular and cellular endocrinology. vol 294. issue 1-2. 2008-12-12. PMID:18790715. |
leptin mainly acts on the hypothalamus in the brain, in which it regulates food intake and energy expenditure. |
2008-12-12 |
2023-08-12 |
mouse |