| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David Carlin. The role of the AMP-activated protein kinase in the regulation of energy homeostasis. Novartis Foundation symposium. vol 286. 2008-04-23. PMID:18269175. |
recent studies have demonstrated that modulation of ampk activity in the hypothalamus plays a role in feeding. |
2008-04-23 |
2023-08-12 |
Not clear |
| Daniel D Lam, Magdalena J Przydzial, Simon H Ridley, Giles S H Yeo, Justin J Rochford, Stephen O'Rahilly, Lora K Heisle. Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology. vol 149. issue 3. 2008-04-22. PMID:18039773. |
in an effort to elucidate the mechanism of this effect, we examined the chemical phenotype of 5-ht(2c)r-expressing neurons in a critical brain region affecting feeding behavior, the arcuate nucleus of the hypothalamus. |
2008-04-22 |
2023-08-12 |
mouse |
| A Valle, N Hoggard, A C Adams, P Roca, J R Speakma. Chronic central administration of apelin-13 over 10 days increases food intake, body weight, locomotor activity and body temperature in C57BL/6 mice. Journal of neuroendocrinology. vol 20. issue 1. 2008-04-16. PMID:18081555. |
apelin and its receptor has also been detected in the arcuate and paraventricular nuclei of the hypothalamus, which are involved in the control of feeding behaviour and energy expenditure. |
2008-04-16 |
2023-08-12 |
mouse |
| K Matsuda, K Wada, T Miura, K Maruyama, S I Shimakura, M Uchiyama, J Leprince, M C Tonon, H Vaudr. Effect of the diazepam-binding inhibitor-derived peptide, octadecaneuropeptide, on food intake in goldfish. Neuroscience. vol 150. issue 2. 2008-04-03. PMID:17936516. |
although endozepines have been localized and characterized in the trout hypothalamus, so far, the action of these neuropeptides on feeding behavior has never been investigated in fish. |
2008-04-03 |
2023-08-12 |
rat |
| J Buteau, D Accil. Regulation of pancreatic beta-cell function by the forkhead protein FoxO1. Diabetes, obesity & metabolism. vol 9 Suppl 2. 2008-03-31. PMID:17919188. |
foxo1 regulates glucose and lipid production in liver; food intake in the hypothalamus and cell differentiation in preadipocytes, myoblasts and vascular endothelium. |
2008-03-31 |
2023-08-12 |
Not clear |
| Catarina Rippe, Charlotte Erlanson-Albertsson, Andreas Lindqvis. Consequences of metabolic challenges on hypothalamic colipase and PLRP2 mRNA in rats. Brain research. vol 1185. 2008-03-28. PMID:17936733. |
this study was performed to elucidate if plrp2, in addition to colipase, is expressed in the hypothalamus and if the mrnas of colipase and plrp2 respond to metabolic challenges such as fasting, high-fat feeding or feeding sugar solutions. |
2008-03-28 |
2023-08-12 |
rat |
| Y Qi, J Iqbal, B J Oldfield, I J Clark. Neural connectivity in the mediobasal hypothalamus of the sheep brain. Neuroendocrinology. vol 87. issue 2. 2008-03-27. PMID:17938564. |
the ventromedial nucleus of the hypothalamus (vmn) and the arcuate nucleus (arc) are two centres regulating energy balance and food intake, but inter-connectivity of these nuclei is not well defined in non-rodent species. |
2008-03-27 |
2023-08-12 |
Not clear |
| Iordanes Karagiannides, Daniel Torres, Yu-Hua Tseng, Collin Bowe, Eugenia Carvalho, Daniel Espinoza, Charalabos Pothoulakis, Efi Kokkoto. Substance P as a novel anti-obesity target. Gastroenterology. vol 134. issue 3. 2008-03-20. PMID:18325388. |
its presence in the hypothalamus and other areas of the brain that regulate feeding as well as in the stomach and small intestine prompted us to investigate its role on appetite control and energy balance. |
2008-03-20 |
2023-08-12 |
Not clear |
| Takashi Kadowaki, Toshimasa Yamauchi, Naoto Kubot. The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS. FEBS letters. vol 582. issue 1. 2008-03-12. PMID:18054335. |
adiponectin enhances amp-activated protein kinase activity in the arcuate hypothalamus via its receptor adipor1 to stimulate food intake and decreases energy expenditure. |
2008-03-12 |
2023-08-12 |
Not clear |
| Chris Pickering, Lotta Avesson, Sture Liljequist, Jonas Lindblom, Helgi B Schiöt. The role of hypothalamic peptide gene expression in alcohol self-administration behavior. Peptides. vol 28. issue 12. 2008-02-27. PMID:17976860. |
therefore, alcohol consumption does seem to involve several hypothalamic systems which also mediate feeding responses and suggests that the hypothalamus, together with the prefrontal cortex, may determine the 'stopping point' of an individual. |
2008-02-27 |
2023-08-12 |
rat |
| Zhihong Guo, Haiyang Jiang, Xiangru Xu, Wenzhen Duan, Mark P Mattso. Leptin-mediated cell survival signaling in hippocampal neurons mediated by JAK STAT3 and mitochondrial stabilization. The Journal of biological chemistry. vol 283. issue 3. 2008-02-14. PMID:17993459. |
leptin plays a pivotal role in the regulation of energy homeostasis and metabolism, primarily by acting on neurons in the hypothalamus that control food intake. |
2008-02-14 |
2023-08-12 |
mouse |
| Ewan C McNa. Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Current opinion in pharmacology. vol 7. issue 6. 2008-01-24. PMID:18023257. |
peptide hormones, initially identified in the periphery and best known for regulation of food intake and appetite, have increasingly been shown to regulate brain functions not only within the hypothalamus but elsewhere. |
2008-01-24 |
2023-08-12 |
Not clear |
| Tadahiro Kitamura, Yukari Ido Kitamur. Role of FoxO Proteins in Pancreatic beta Cells. Endocrine journal. vol 54. issue 4. 2008-01-14. PMID:17510498. |
in the hypothalamus, foxo controls food intake. |
2008-01-14 |
2023-08-12 |
Not clear |
| Ana C Ribeiro, Evelyn Sawa, Isabelle Carren-LeSauter, Joseph LeSauter, Rae Silver, Donald W Pfaf. Two forces for arousal: Pitting hunger versus circadian influences and identifying neurons responsible for changes in behavioral arousal. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 50. 2008-01-11. PMID:18056628. |
the number of c-fos+ neurons was significantly increased only in the ventromedial nucleus of the hypothalamus (vmh) in these mice, compared with control animals whose feeding was restricted to their normal active and feeding time (p < 0.01). |
2008-01-11 |
2023-08-12 |
mouse |
| Ruth McPherso. Genetic contributors to obesity. The Canadian journal of cardiology. vol 23 Suppl A. 2008-01-10. PMID:17668084. |
these genes can be considered in four broad categories: regulation of food intake by molecular signalling in the hypothalamus and hindbrain by signals originating in adipose tissue, gut and other organs; regulation of adipocyte differentiation and fat storage; regulation of spontaneous exercise activity; and effect on basal and postprandial thermogenesis. |
2008-01-10 |
2023-08-12 |
mouse |
| K Czaja, C R Barb, R R Kraelin. Hypothalamic neurons innervating fat tissue in the pig express leptin receptor immunoreactivity. Neuroscience letters. vol 425. issue 1. 2008-01-09. PMID:17720315. |
our results provide the morphological data on multisynaptic projections from hypothalamus to the fat tissue in the pig and demonstrate that these neurons, located in areas involved in reproductive processes and feeding behavior, may regulate fat tissue metabolism. |
2008-01-09 |
2023-08-12 |
Not clear |
| Ruth Simon, Thomas Lufkin, Andrew D Bergeman. Homeobox gene Sax2 deficiency causes an imbalance in energy homeostasis. Developmental dynamics : an official publication of the American Association of Anatomists. vol 236. issue 10. 2008-01-09. PMID:17879320. |
the brain, in particular the hypothalamus and the brainstem, plays a critical role in the regulation of energy homeostasis by incorporating signals from the periphery and translating them into feeding behavior. |
2008-01-09 |
2023-08-12 |
Not clear |
| N Smolinska, G Siawrys, T Kaminski, J Przal. Leptin gene and protein expression in the trophoblast and uterine tissues during early pregnancy and the oestrous cycle of pigs. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 58. issue 3. 2007-12-21. PMID:17928651. |
leptin is a 16-kda protein hormone encoded by the obese (ob) gene and acts on receptors in the hypothalamus to regulate food intake and energy balance. |
2007-12-21 |
2023-08-12 |
mouse |
| Benedek Erdös, Christopher S Broxson, Tessa Landa, Philip J Scarpace, Christiaan Leeuwenburgh, Yi Zhang, Nihal Tüme. Effects of life-long caloric restriction and voluntary exercise on age-related changes in levels of catecholamine biosynthetic enzymes and angiotensin II receptors in the rat adrenal medulla and hypothalamus. Experimental gerontology. vol 42. issue 8. 2007-12-19. PMID:17540525. |
these data indicate that a small decrease in daily food intake can avert age-related changes in catecholamine biosynthetic enzyme levels in the adrenal medulla and hypothalamus, possibly through affecting angiotensin ii signaling. |
2007-12-19 |
2023-08-12 |
rat |
| Carla M R Germano, Margaret de Castro, Rodrigo Rorato, Maria Teresa C Laguna, Jose Antunes-Rodrigues, Carol F Elias, Lucila L K Elia. Time course effects of adrenalectomy and food intake on cocaine- and amphetamine-regulated transcript expression in the hypothalamus. Brain research. vol 1166. 2007-12-13. PMID:17669377. |
time course effects of adrenalectomy and food intake on cocaine- and amphetamine-regulated transcript expression in the hypothalamus. |
2007-12-13 |
2023-08-12 |
rat |