| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shao-Xian Wang, Jia-Xu Chen, Guang-Xin Yue, Ming-Hua Bai, Mei-Jing Kou, Zhong-Ye Ji. Xiaoyaosan decoction regulates changes in neuropeptide y and leptin receptor in the rat arcuate nucleus after chronic immobilization stress. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-12-18. PMID:23243440. |
weight loss and decreased food intake in rats caused by the binding of leptin to ob-r in hypothalamus do not appear to utilize the npy pathway. |
2012-12-18 |
2023-08-12 |
rat |
| Seung-Hyun Hong, Kyu-Sun Lee, Su-Jin Kwak, Ae-Kyeong Kim, Hua Bai, Min-Su Jung, O-Yu Kwon, Woo-Joo Song, Marc Tatar, Kweon Y. Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals. PLoS genetics. vol 8. issue 8. 2012-12-17. PMID:22876196. |
furthermore, human dyrk1a transgenic mice exhibited decreased foxo acetylation and increased npy expression in the hypothalamus, and [corrected] increased food intake. |
2012-12-17 |
2023-08-12 |
mouse |
| Keisuke Suzuki, Channa N Jayasena, Stephen R Bloo. Obesity and appetite control. Experimental diabetes research. vol 2012. 2012-12-11. PMID:22899902. |
furthermore, the hypothalamus integrates a number of peripheral signals which modulate food intake and energy expenditure. |
2012-12-11 |
2023-08-12 |
human |
| K A Frahm, M J Schow, S A Tobe. The vasculature within the paraventricular nucleus of the hypothalamus in mice varies as a function of development, subnuclear location, and GABA signaling. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 44. issue 8. 2012-11-29. PMID:22488519. |
the paraventricular nucleus of the hypothalamus (pvn) is a cell group that plays important roles in regulating sympathetic vasomotor tone, food intake, neuroendocrine and autonomic stress responses, and cardiovascular function. |
2012-11-29 |
2023-08-12 |
mouse |
| Marta Librán-Pérez, Sergio Polakof, Marcos A López-Patiño, Jesús M Míguez, José L Soenga. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 11. 2012-11-29. PMID:22496361. |
evidence of a metabolic fatty acid-sensing system in the hypothalamus and brockmann bodies of rainbow trout: implications in food intake regulation. |
2012-11-29 |
2023-08-12 |
Not clear |
| Marta Librán-Pérez, Sergio Polakof, Marcos A López-Patiño, Jesús M Míguez, José L Soenga. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 11. 2012-11-29. PMID:22496361. |
the increase in circulating lcfa or mcfa levels elicited an inhibition in food intake and induced in the hypothalamus a response compatible with fatty acid sensing in which fatty acid metabolism, binding to cluster of differentiation 36 (cd36), and mitochondrial activity are apparently involved, which is similar to that suggested in mammals except for the apparent capacity of rainbow trout to detect changes in mcfa levels. |
2012-11-29 |
2023-08-12 |
Not clear |
| Marta Librán-Pérez, Sergio Polakof, Marcos A López-Patiño, Jesús M Míguez, José L Soenga. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 11. 2012-11-29. PMID:22496361. |
this response seems to be exclusive for the hypothalamus, since the other center controlling food intake (hindbrain) was unaffected by treatments. |
2012-11-29 |
2023-08-12 |
Not clear |
| Marta Librán-Pérez, Sergio Polakof, Marcos A López-Patiño, Jesús M Míguez, José L Soenga. Evidence of a metabolic fatty acid-sensing system in the hypothalamus and Brockmann bodies of rainbow trout: implications in food intake regulation. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 11. 2012-11-29. PMID:22496361. |
therefore, the present study provides, for the first time in fish, evidence for a specific role for fa (mcfa and lcfa) as metabolic signals in hypothalamus and bb, where the detection of those fa can be associated with the control of food intake and hormone release. |
2012-11-29 |
2023-08-12 |
Not clear |
| María Sol Kruse, Mariana Rey, María Cristina Vega, Héctor Coirin. Alterations of LXRα and LXRβ expression in the hypothalamus of glucose-intolerant rats. The Journal of endocrinology. vol 215. issue 1. 2012-11-29. PMID:22836489. |
this is the first study showing a relationship between glucose and lipid homeostasis and the expression of lxrs in the hypothalamus, suggesting that lxrs may trigger neurochemical and neurophysiological responses for the control of food intake and energy expenditure through these receptors. |
2012-11-29 |
2023-08-12 |
rat |
| Camila Calvino, Luana L Souza, Ricardo H Costa-e-Sousa, Norma A S Almeida, Isis H Trevenzoli, Carmen C Pazos-Mour. Hypothyroidism reduces ObRb-STAT3 leptin signalling in the hypothalamus and pituitary of rats associated with resistance to leptin acute anorectic action. The Journal of endocrinology. vol 215. issue 1. 2012-11-29. PMID:22875962. |
therefore, hypothyroidism decreased obrb-stat3 signalling in the hypothalamus and pituitary gland, which likely contributes to the loss of leptin action on food intake and tsh secretion, as previously observed in hypothyroid rats. |
2012-11-29 |
2023-08-12 |
rat |
| Amy D Nguyen, Natalie F Mitchell, Shu Lin, Laurence Macia, Ernie Yulyaningsih, Paul A Baldock, Ronaldo F Enriquez, Lei Zhang, Yan-Chuan Shi, Serge Zolotukhin, Herbert Herzog, Amanda Sainsbur. Y1 and Y5 receptors are both required for the regulation of food intake and energy homeostasis in mice. PloS one. vol 7. issue 6. 2012-11-27. PMID:22768253. |
germline y1y5 ablation in y1y5(-/-) mice results in hypophagia, an effect that is at least partially mediated by the hypothalamus, since mice with adult-onset y1y5 receptor dual ablation targeted to the paraventricular nucleus (pvn) of the hypothalamus (y1y5(hyp/hyp)) also exhibit reduced spontaneous or fasting-induced food intake when fed a high fat diet. |
2012-11-27 |
2023-08-12 |
mouse |
| Pieter-Jan Verhulst, Inge Depoorter. Ghrelin's second life: from appetite stimulator to glucose regulator. World journal of gastroenterology. vol 18. issue 25. 2012-11-21. PMID:22783041. |
ghrelin stimulates food intake through binding to its receptor (grln-r) on neurons in the arcuate nucleus of the hypothalamus. |
2012-11-21 |
2023-08-12 |
Not clear |
| Wen-Shan Lv, Jun-Ping Wen, Li Li, Rui-Xia Sun, Jing Wang, Yu-Xin Xian, Cai-Xia Cao, Yun-Long Wang, Yan-Yan Ga. The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats. Brain research. vol 1444. 2012-11-13. PMID:22325091. |
our findings suggest that metformin may cross bbb and play a central mechanism on regulation of food intake in the hypothalamus. |
2012-11-13 |
2023-08-12 |
rat |
| Songbo Wang, Paul Khondowe, Shengfeng Chen, Jianjian Yu, Gang Shu, Xiaotong Zhu, Lina Wang, Ping Gao, Qianyun Xi, Yongliang Zhang, Qingyan Jian. Effects of "Bioactive" amino acids leucine, glutamate, arginine and tryptophan on feed intake and mRNA expression of relative neuropeptides in broiler chicks. Journal of animal science and biotechnology. vol 3. issue 1. 2012-11-13. PMID:22958345. |
these findings suggested that l-leucine and l-glutamate could act within the hypothalamus to influence food intake, and that both orexigenic and anorexigenic neuropeptide genes might contribute directly to these effects. |
2012-11-13 |
2023-08-12 |
Not clear |
| E Tavares, R Maldonado, A Garcia-Martinez, F J Miñan. Central administration of aminoprocalcitonin inhibits food intake and stimulates the hypothalamic-pituitary-adrenal axis in rats via the corticotrophin-releasing factor system. Journal of neuroendocrinology. vol 24. issue 7. 2012-11-08. PMID:22372932. |
intracerebroventricular n-pct administration increased crf mrna and content in the hypothalamus, suggesting that n-pct stimulates the hpa axis and suppresses food intake and body weight via crf-dependent pathways. |
2012-11-08 |
2023-08-12 |
rat |
| Jennifer A Mohawk, Carla B Green, Joseph S Takahash. Central and peripheral circadian clocks in mammals. Annual review of neuroscience. vol 35. 2012-11-07. PMID:22483041. |
in the central suprachiasmatic nucleus (scn) of the hypothalamus, a coupled population of neuronal circadian oscillators acts as a master pacemaker for the organism to drive rhythms in activity and rest, feeding, body temperature, and hormones. |
2012-11-07 |
2023-08-12 |
Not clear |
| Marta Conde-Sieira, Marta Librán-Pérez, Marcos A López Patiño, José L Soengas, Jesús M Mígue. Melatonin treatment alters glucosensing capacity and mRNA expression levels of peptides related to food intake control in rainbow trout hypothalamus. General and comparative endocrinology. vol 178. issue 1. 2012-10-31. PMID:22569117. |
melatonin treatment alters glucosensing capacity and mrna expression levels of peptides related to food intake control in rainbow trout hypothalamus. |
2012-10-31 |
2023-08-12 |
Not clear |
| Pierre Cardinal, Luigi Bellocchio, Samantha Clark, Astrid Cannich, Matthias Klugmann, Beat Lutz, Giovanni Marsicano, Daniela Cot. Hypothalamic CB1 cannabinoid receptors regulate energy balance in mice. Endocrinology. vol 153. issue 9. 2012-10-29. PMID:22778221. |
the hypothalamus plays a critical role in regulating energy balance by modulating both food intake and energy expenditure. |
2012-10-29 |
2023-08-12 |
mouse |
| Weihong Pan, Hung Hsuchou, Bhavaani Jayaram, Reas S Khan, Eagle Yi-Kung Huang, Xiaojun Wu, Chu Chen, Abba J Kasti. Leptin action on nonneuronal cells in the CNS: potential clinical applications. Annals of the New York Academy of Sciences. vol 1264. 2012-10-25. PMID:22530983. |
we first summarize the distribution of leptin receptors in the brain, with a focus on the hypothalamus, where the leptin receptor is known to mediate essential feeding suppression activities, and on the hippocampus, where leptin facilitates memory, reduces neurodegeneration, and plays a dual role in seizures. |
2012-10-25 |
2023-08-12 |
mouse |
| Sarah M Rothman, Kathleen J Griffioen, Ruiqian Wan, Mark P Mattso. Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Annals of the New York Academy of Sciences. vol 1264. 2012-10-25. PMID:22548651. |
in the hypothalamus, bdnf inhibits food intake and increases energy expenditure. |
2012-10-25 |
2023-08-12 |
Not clear |