| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroshi Urabe, Hideto Kojima, Lawrence Chan, Tomoya Terashima, Nobuhiro Ogawa, Miwako Katagi, Kazunori Fujino, Asako Kumagai, Hiromichi Kawai, Akihiro Asakawa, Akio Inui, Hitoshi Yasuda, Yutaka Eguchi, Kazuhiro Oka, Hiroshi Maegawa, Atsunori Kashiwagi, Hiroshi Kimur. Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus. Nature communications. vol 4. 2013-06-20. PMID:23443554. |
brain-derived neurotrophic factor (bdnf) suppresses food intake by acting on neurons in the hypothalamus. |
2013-06-20 |
2023-08-12 |
mouse |
| Daniela F Bertelli, Andressa Coope, Andrea M Caricilli, Patricia O Prada, Mario J Saad, Licio A Velloso, Eliana P Arauj. Inhibition of 72 kDa inositol polyphosphate 5-phosphatase E improves insulin signal transduction in diet-induced obesity. The Journal of endocrinology. vol 217. issue 2. 2013-06-19. PMID:23349329. |
the reduction of 72k-5ptase expression in the hypothalamus results in improved hypothalamic insulin signal transduction and reduction of food intake and body mass. |
2013-06-19 |
2023-08-12 |
mouse |
| Kiran S Panicka. Effects of dietary polyphenols on neuroregulatory factors and pathways that mediate food intake and energy regulation in obesity. Molecular nutrition & food research. vol 57. issue 1. 2013-06-18. PMID:23125162. |
food intake is subject to a complex regulation by the hypothalamus and other brain centers including the brain stem and the hippocampus. |
2013-06-18 |
2023-08-12 |
human |
| Takao Kaji, Katsunori Nonogak. Role of homeobox genes in the hypothalamic development and energy balance. Frontiers in bioscience (Landmark edition). vol 18. 2013-06-12. PMID:23276958. |
in the adult stage, bsx and ttf-1 continue to be expressed in the hypothalamus, including the arc, and serve as transcription factors of neuropeptide y and agouti-related protein. the expression of hypothalamic bsx and ttf-1 can be altered by the feeding state and appetite regulatory hormones such as ghrelin and leptin. |
2013-06-12 |
2023-08-12 |
mouse |
| Arjen J Boender, Andrea J van Rozen, Roger A H Ada. Nutritional state affects the expression of the obesity-associated genes Etv5, Faim2, Fto, and Negr1. Obesity (Silver Spring, Md.). vol 20. issue 12. 2013-06-11. PMID:22627920. |
to gain more insight into the neurobiological mechanisms involved, we set out to investigate the effect of dietary exposure on the expression levels of obesity-associated genes in the ventro-medial hypothalamus (vmh)/arcuate nucleus (arc) and the substantia nigra (sn)/ventral tegmental area (vta), two brain regions that are implicated in feeding behavior. |
2013-06-11 |
2023-08-12 |
Not clear |
| Jose M Lerma-Cabrera, Francisca Carvajal, Gabriela Chotro, Mirari Gaztañaga, Montserrat Navarro, Todd E Thiele, Inmaculada Cuber. MC4-R signaling within the nucleus accumbens shell, but not the lateral hypothalamus, modulates ethanol palatability in rats. Behavioural brain research. vol 239. 2013-06-04. PMID:23146409. |
the roles of endogenous mc and mc-4 receptor (mc4-r) signaling within the hypothalamus in the control of homeostatic aspects of feeding are well established. |
2013-06-04 |
2023-08-12 |
rat |
| Masayuki Nakazawa, Yoko Obata, Tomoya Nishino, Shinichi Abe, Yuka Nakazawa, Katsushige Abe, Akira Furusu, Masanobu Miyazaki, Takehiko Koji, Shigeru Kohn. Involvement of leptin in the progression of experimentally induced peritoneal fibrosis in mice. Acta histochemica et cytochemica. vol 46. issue 2. 2013-05-31. PMID:23720606. |
leptin is a hormone mainly produced by white adipose cells, and regulates body fat and food intake by acting on hypothalamus. |
2013-05-31 |
2023-08-12 |
mouse |
| Yun-Hee Choi, Teppei Fujikawa, Jiwon Lee, Anne Reuter, Ki Woo Ki. Revisiting the Ventral Medial Nucleus of the Hypothalamus: The Roles of SF-1 Neurons in Energy Homeostasis. Frontiers in neuroscience. vol 7. 2013-05-16. PMID:23675313. |
in the early twentieth century, the ventral medial nucleus of the hypothalamus (vmh) was the first site reported to play a prominent role in the regulation of energy homeostasis through control of food intake and energy expenditure. |
2013-05-16 |
2023-08-12 |
Not clear |
| N Torres, S Chabardes, B Piallat, A Devergnas, A L Benabi. Body fat and body weight reduction following hypothalamic deep brain stimulation in monkeys: an intraventricular approach. International journal of obesity (2005). vol 36. issue 12. 2013-05-15. PMID:22349575. |
the authors proposed an intraventricular 'floating' electrode inserted in the third ventricle (v3) adjacent to the ventromedian hypothalamus (vmh) in a freely moving macaca fascicularis to modulate food intake (fi), body fat (bf), body weight (bw) and body mass index (bmi), as a potential treatment of obesity. |
2013-05-15 |
2023-08-12 |
monkey |
| Alexander V Sirotkin, Silvia Pavlova, Manuel Tena-Sempere, Roland Grossmann, Magdalena Romero Jiménez, Juan Manuel Castellano Rodriguez, Francisco Valenzuel. Food restriction, ghrelin, its antagonist and obestatin control expression of ghrelin and its receptor in chicken hypothalamus and ovary. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 164. issue 1. 2013-05-09. PMID:22877785. |
our results (1) confirm the existence of ghrelin and its functional receptors ghs-r1a in the chicken hypothalamus and ovary (2) confirm the age-dependent control of ovarian ghrelin by feeding, (3) demonstrate, that nutritional status can influence the expression of both ghrelin and ghs-r1a in hypothalamus and in the ovary (3) demonstrates for the first time, that ghrelin can promote generation of its functional receptor in the hypothalamus, but not in the ovary, (4) show that ghrelin1-18 and (d-lys-3)-ghrp-6 could not only be antagonists in the action on chicken hypothalamus and ovaries, but also independent regulators and even agonists, and (5) provide first evidence for action of obestatin on hypothalamic ghrelin and on the response of hypothalamic and ovarian ghrelin/ghs-r1a system to food restriction. |
2013-05-09 |
2023-08-12 |
chicken |
| Haruaki Kageyama, Fumiko Takenoya, Satoshi Hirako, Nobuhiro Wada, Yuri Kintaka, Shuji Inoue, Eiji Ota, Tetsuo Ogawa, Seiji Shiod. Neuronal circuits involving neuropeptide Y in hypothalamic arcuate nucleus-mediated feeding regulation. Neuropeptides. vol 46. issue 6. 2013-05-06. PMID:23110814. |
accumulated evidence shows that hypothalamic neuropeptides such as ghrelin, orexin, melanin-concentrating hormone (mch), galanin-like peptide (galp) and proopiomelanocortin (pomc) are involved in the regulation of feeding behavior and energy homeostasis via neuronal circuits in the hypothalamus. |
2013-05-06 |
2023-08-12 |
Not clear |
| Cheng Zhan, Jingfeng Zhou, Qiru Feng, Ju-En Zhang, Shuailiang Lin, Junhong Bao, Ping Wu, Minmin Lu. Acute and long-term suppression of feeding behavior by POMC neurons in the brainstem and hypothalamus, respectively. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 8. 2013-04-24. PMID:23426689. |
acute and long-term suppression of feeding behavior by pomc neurons in the brainstem and hypothalamus, respectively. |
2013-04-24 |
2023-08-12 |
mouse |
| Samira Fargali, Masato Sadahiro, Cheng Jiang, Amy L Frick, Tricia Indall, Valeria Cogliani, Jelle Welagen, Wei-Jye Lin, Stephen R Salto. Role of neurotrophins in the development and function of neural circuits that regulate energy homeostasis. Journal of molecular neuroscience : MN. vol 48. issue 3. 2013-04-19. PMID:22581449. |
a subset of the neurotrophin-dependent pathways in the hypothalamus, brainstem, and spinal cord, and those that project via the sympathetic nervous system to peripheral metabolic tissues including brown and white adipose tissue, muscle and liver, regulate feeding, energy storage, and energy expenditure. |
2013-04-19 |
2023-08-12 |
Not clear |
| Huxing Cui, Jong-Woo Sohn, Laurent Gautron, Hisayuki Funahashi, Kevin W Williams, Joel K Elmquist, Michael Lutte. Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area. The Journal of comparative neurology. vol 520. issue 18. 2013-04-18. PMID:22605619. |
the lateral hypothalamic area (lha) receives dense melanocortinergic inputs from the arcuate nucleus of the hypothalamus and regulates multiple processes including food intake, reward behaviors, and autonomic function. |
2013-04-18 |
2023-08-12 |
mouse |
| Jasbir Dalal, Jee Hoon Roh, Susan E Maloney, Afua Akuffo, Samir Shah, Han Yuan, Brie Wamsley, Wendell B Jones, Cristina de Guzman Strong, Paul A Gray, David M Holtzman, Nathaniel Heintz, Joseph D Doughert. Translational profiling of hypocretin neurons identifies candidate molecules for sleep regulation. Genes & development. vol 27. issue 5. 2013-04-18. PMID:23431030. |
hypocretin (orexin; hcrt)-containing neurons of the hypothalamus are essential for the normal regulation of sleep and wake behaviors and have been implicated in feeding, anxiety, depression, and reward. |
2013-04-18 |
2023-08-12 |
mouse |
| Abdulkerim Kasim Baltaci, Rasim Mogulko. Leptin and zinc relation: In regulation of food intake and immunity. Indian journal of endocrinology and metabolism. vol 16. issue Suppl 3. 2013-04-09. PMID:23565497. |
leptin, which carries the information about energy reserves of the body to the brain, controls food intake by acting on neuropeptide y (npy), which exercises a food-intake-increasing effect through relevant receptors in the hypothalamus. |
2013-04-09 |
2023-08-12 |
Not clear |
| H Jonaidi, Z Noor. Neuropeptide Y-induced feeding is dependent on GABAA receptors in neonatal chicks. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 198. issue 11. 2013-04-05. PMID:22972230. |
in rats, significant evidence suggest a functional and behavioral interaction between npy and gaba mediated transmission in various brain regions, including the arcuate and paraventricular nuclei of the hypothalamus which can be important in the regulation of feeding behavior. |
2013-04-05 |
2023-08-12 |
rat |
| b' Rojo Rasoamanana, Nicolas Darcel, Gilles Fromentin, Daniel Tom\\xc3\\xa. Nutrient sensing and signalling by the gut. The Proceedings of the Nutrition Society. vol 71. issue 4. 2013-04-04. PMID:22453062.' |
this informs central nuclei involved in the control of feeding such as the hypothalamus and nucleus of the solitary tract of the availability of these nutrients and thus triggers adaptive responses to maintain energy homoeostasis. |
2013-04-04 |
2023-08-12 |
Not clear |
| Carlos Dombret, Tuan Nguyen, Olivier Schakman, Jacques L Michaud, Hélène Hardin-Pouzet, Mathieu J M Bertrand, Olivier De Backe. Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus. Human molecular genetics. vol 21. issue 21. 2013-04-03. PMID:22865874. |
oxytocin (ot), which is produced in the hypothalamus, can act as a neurotransmitter that reduces anxiety, promotes social behaviors and regulates food intake. |
2013-04-03 |
2023-08-12 |
mouse |
| Kanta Mizusawa, Noriko Amiya, Yoko Yamaguchi, Souichirou Takabe, Masafumi Amano, Jason P Breves, Bradley K Fox, E Gordon Grau, Susumu Hyodo, Akiyoshi Takahash. Identification of mRNAs coding for mammalian-type melanin-concentrating hormone and its receptors in the scalloped hammerhead shark Sphyrna lewini. General and comparative endocrinology. vol 179. issue 1. 2013-03-21. PMID:22884735. |
these results indicate that mch does not have a peripheral function, such as a melanin-concentrating effect, in the skin of s. lewini hypothalamic mch mrna levels were not affected by fasting, suggesting that feeding conditions might not affect the expression of mch in the hypothalamus. |
2013-03-21 |
2023-08-12 |
Not clear |