| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sahu, C A Sninsky, S P Kalr. Evidence that hypothalamic neuropeptide Y gene expression and NPY levels in the paraventricular nucleus increase before the onset of hyperphagia in experimental diabetes. Brain research. vol 755. issue 2. 1997-08-07. PMID:9175903. |
these results show that augmentation in npy neuronal activity in the arc-pvn axis precedes the onset of increased food intake produced by stz-induced insulinopenia. |
1997-08-07 |
2023-08-12 |
rat |
| A A Balasubramania. Neuropeptide Y family of hormones: receptor subtypes and antagonists. Peptides. vol 18. issue 3. 1997-07-17. PMID:9145434. |
npy exhibits a variety of potent central and peripheral effects including those on feeding, memory, blood pressure, cardiac contractility and intestinal secretions. |
1997-07-17 |
2023-08-12 |
Not clear |
| J D Pomonis, A S Levine, C J Billingto. Interaction of the hypothalamic paraventricular nucleus and central nucleus of the amygdala in naloxone blockade of neuropeptide Y-induced feeding revealed by c-fos expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185555. |
neuropeptide y (npy) is a powerful inducer of food intake with a key site of action in the paraventricular nucleus (pvn) of the hypothalamus. |
1997-07-17 |
2023-08-12 |
Not clear |
| J D Pomonis, A S Levine, C J Billingto. Interaction of the hypothalamic paraventricular nucleus and central nucleus of the amygdala in naloxone blockade of neuropeptide Y-induced feeding revealed by c-fos expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185555. |
injection of npy into the pvn resulted in an increase in food intake that was blocked by peripheral administration of naloxone. |
1997-07-17 |
2023-08-12 |
Not clear |
| J D Pomonis, A S Levine, C J Billingto. Interaction of the hypothalamic paraventricular nucleus and central nucleus of the amygdala in naloxone blockade of neuropeptide Y-induced feeding revealed by c-fos expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185555. |
pvn npy also resulted in increased cfos immunoreactivity (cfos-ir) in the pvn independent of food intake, and although peripheral naloxone inhibited npy-induced feeding, it did not alter cfos-ir in the pvn. |
1997-07-17 |
2023-08-12 |
Not clear |
| J D Pomonis, A S Levine, C J Billingto. Interaction of the hypothalamic paraventricular nucleus and central nucleus of the amygdala in naloxone blockade of neuropeptide Y-induced feeding revealed by c-fos expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 13. 1997-07-17. PMID:9185555. |
three other brain regions, the nucleus of the solitary tract, the ventrolateral medulla, and the supraoptic nucleus, all showed increases in cfos-ir in this study, but these changes came only as a result of increased food intake after pvn-injected npy. |
1997-07-17 |
2023-08-12 |
Not clear |
| G L Edwards, B D White, B He, R G Dean, R J Marti. Elevated hypothalamic neuropeptide Y levels in rats with dorsomedial hindbrain lesions. Brain research. vol 755. issue 1. 1997-07-16. PMID:9163543. |
these data suggest the possibility that elevated hypothalamic npy, particularly in the arcuate and paraventricular nuclei, may contribute to the altered food intake and energy balance observed in rats with lesions centered on the ap. |
1997-07-16 |
2023-08-12 |
rat |
| B K Smith, H R Berthoud, D A York, G A Bra. Differential effects of baseline macronutrient preferences on macronutrient selection after galanin, NPY, and an overnight fast. Peptides. vol 18. issue 2. 1997-07-14. PMID:9149292. |
in counterbalanced tests conducted on separate days, saline, galanin, or npy was infused into the paraventricular nucleus of the hypothalamus and 60-min food intake was measured. |
1997-07-14 |
2023-08-12 |
rat |
| H Herzog, K Darby, H Ball, Y Hort, A Beck-Sickinger, J Shin. Overlapping gene structure of the human neuropeptide Y receptor subtypes Y1 and Y5 suggests coordinate transcriptional regulation. Genomics. vol 41. issue 3. 1997-07-01. PMID:9169127. |
as both y1 and y5 receptors are thought to play an important role in the regulation of food intake, coordinate expression of their specific genes may be important in the modulation of npy activity. |
1997-07-01 |
2023-08-12 |
human |
| G Wol. Neuropeptides responding to leptin. Nutrition reviews. vol 55. issue 3. 1997-06-19. PMID:9170895. |
leptin, the circulating protein that inhibits food intake and energy expenditure, was thought to function through inhibition of the hypothalamic neuropeptide y (npy), a stimulator of food intake. |
1997-06-19 |
2023-08-12 |
mouse |
| G Wol. Neuropeptides responding to leptin. Nutrition reviews. vol 55. issue 3. 1997-06-19. PMID:9170895. |
however, mouse mutants lacking npy are normal, suggesting that alternative neuromodulators of food intake must exist. |
1997-06-19 |
2023-08-12 |
mouse |
| P Du, J A Salon, J A Tamm, C Hou, W Cui, M W Walker, N Adham, D S Dhanoa, I Islam, P J Vaysse, B Dowling, Y Shifman, N Boyle, H Rueger, T Schmidlin, Y Yamaguchi, T A Branchek, R L Weinshank, C Gluchowsk. Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites. Protein engineering. vol 10. issue 2. 1997-06-03. PMID:9089810. |
neuropeptide y (npy) receptors belong to the g-protein-coupled receptor (gpcr) superfamily and mediate several physiological responses, such as blood pressure, food intake, sedation and memory retention. |
1997-06-03 |
2023-08-12 |
Not clear |
| M L Barker-Gibb, I J Clark. Increased galanin and neuropeptide-Y immunoreactivity within the hypothalamus of ovariectomised ewes following a prolonged period of reduced body weight is associated with changes in plasma growth hormone but not gonadotropin levels. Neuroendocrinology. vol 64. issue 3. 1997-05-22. PMID:8875437. |
we have studied ovariectomised ewes that were either well-fed (highs) or underfed (lows) and used immunocytochemistry and image analysis to measure the levels of gal and npy in hypothalamic nuclei in which gnrh, ghrh and srih are found and which are also involved in the regulation of appetite and feeding. |
1997-05-22 |
2023-08-12 |
Not clear |
| D G Morgan, P D Lambert, D M Smith, J P Wilding, S R Bloo. Reduced NPY induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. Journal of neuroendocrinology. vol 8. issue 4. 1997-05-09. PMID:8861284. |
reduced npy induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. |
1997-05-09 |
2023-08-12 |
rat |
| D G Morgan, P D Lambert, D M Smith, J P Wilding, S R Bloo. Reduced NPY induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. Journal of neuroendocrinology. vol 8. issue 4. 1997-05-09. PMID:8861284. |
npy exhibited reduced feeding responses compared to controls (p < 0.05). |
1997-05-09 |
2023-08-12 |
rat |
| D G Morgan, P D Lambert, D M Smith, J P Wilding, S R Bloo. Reduced NPY induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. Journal of neuroendocrinology. vol 8. issue 4. 1997-05-09. PMID:8861284. |
feeding responses were also measured in this model, to assess whether high levels of endogenous npy might account for the reduced response in diabetes. |
1997-05-09 |
2023-08-12 |
rat |
| D G Morgan, P D Lambert, D M Smith, J P Wilding, S R Bloo. Reduced NPY induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. Journal of neuroendocrinology. vol 8. issue 4. 1997-05-09. PMID:8861284. |
in contrast, the feeding response to npy in comparison to controls was unaltered in dexamethasone treated rats. |
1997-05-09 |
2023-08-12 |
rat |
| D G Morgan, P D Lambert, D M Smith, J P Wilding, S R Bloo. Reduced NPY induced feeding in diabetic but not steroid-treated rats: lack of evidence for changes in receptor number or affinity. Journal of neuroendocrinology. vol 8. issue 4. 1997-05-09. PMID:8861284. |
the feeding response to exogenous npy is reduced in experimental diabetes, but not in dexamethasone treated rats. |
1997-05-09 |
2023-08-12 |
rat |
| F F Matos, V Guss, C Korpine. Effects of neuropeptide Y (NPY) and [D-Trp32]NPY on monoamine and metabolite levels in dialysates from rat hypothalamus during feeding behavior. Neuropeptides. vol 30. issue 4. 1997-05-08. PMID:8914867. |
effects of neuropeptide y (npy) and [d-trp32]npy on monoamine and metabolite levels in dialysates from rat hypothalamus during feeding behavior. |
1997-05-08 |
2023-08-12 |
rat |
| F F Matos, V Guss, C Korpine. Effects of neuropeptide Y (NPY) and [D-Trp32]NPY on monoamine and metabolite levels in dialysates from rat hypothalamus during feeding behavior. Neuropeptides. vol 30. issue 4. 1997-05-08. PMID:8914867. |
since monoamines have been suggested to be involved in npy-induced feeding, we investigated the effects of npy and [d-trp32]npy, a putative npy antagonist, on extracellular levels of norepinephrine (ne), dopamine (da), serotonin (5-ht), 3,4-dihydroxyphenyl acetic acid (dopac), homovanillic acid (hva) and 5-hydroxyindole-3-acetic acid (5-hiaa) in the hypothalamus, including the paraventricular hypothalamic nuclei (pvn), during feeding behavior. |
1997-05-08 |
2023-08-12 |
rat |