| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Dyer, J M Simmons, R L Matteri, D H Keisle. Effects of an intravenous injection of NPY on leptin and NPY-Y1 receptor mRNA expression in ovine adipose tissue. Domestic animal endocrinology. vol 14. issue 5. 1997-11-25. PMID:9347253. |
neuropeptide y (npy) is highly expressed in hypothalami of undernourished and genetically obese animals, and is a potent regulator of food intake and reproduction. |
1997-11-25 |
2023-08-12 |
Not clear |
| C J Small, D G Morgan, K Meeran, M M Heath, I Gunn, C M Edwards, J Gardiner, G M Taylor, J D Hurley, M Rossi, A P Goldstone, D O'Shea, D M Smith, M A Ghatei, S R Bloo. Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326671. |
intracerebroventricular administration of npy to male rats significantly increased plasma acth 10 min after injection and stimulated 2-h food intake. |
1997-11-24 |
2023-08-12 |
human |
| C J Small, D G Morgan, K Meeran, M M Heath, I Gunn, C M Edwards, J Gardiner, G M Taylor, J D Hurley, M Rossi, A P Goldstone, D O'Shea, D M Smith, M A Ghatei, S R Bloo. Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326671. |
interestingly, neither [pro34]npy(13-36) nor the selective y5 receptor agonist [d-trp32]npy stimulated food intake, whereas both significantly increased plasma acth. |
1997-11-24 |
2023-08-12 |
human |
| C J Small, D G Morgan, K Meeran, M M Heath, I Gunn, C M Edwards, J Gardiner, G M Taylor, J D Hurley, M Rossi, A P Goldstone, D O'Shea, D M Smith, M A Ghatei, S R Bloo. Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326671. |
thus the hypothalamic npy receptor mediating increases in plasma acth has a fragment activation profile unlike the y1-y4 or y6 receptors and appears distinct from the npy receptor controlling food intake. |
1997-11-24 |
2023-08-12 |
human |
| A O Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, S Whitebread, L Criscione, K G Hofbaue. Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides. Diabetes. vol 46. issue 11. 1997-11-21. PMID:9356028. |
the recently discovered rat neuropeptide y (npy) receptor, the y5 subtype, has been proposed to mediate the npy-induced feeding response and therefore plays a central role in the regulation of food intake. |
1997-11-21 |
2023-08-12 |
rat |
| A O Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, S Whitebread, L Criscione, K G Hofbaue. Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides. Diabetes. vol 46. issue 11. 1997-11-21. PMID:9356028. |
npy antisense odns given intracerebroventricularly to rats prevented the increase in hypothalamic npy levels during food deprivation and inhibited fasting-induced food intake. |
1997-11-21 |
2023-08-12 |
rat |
| A O Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, S Whitebread, L Criscione, K G Hofbaue. Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides. Diabetes. vol 46. issue 11. 1997-11-21. PMID:9356028. |
moreover, two y5 antisense odns, targeted to different sequences of the receptor, significantly decreased basal food intake and inhibited the increase in food intake after intracerebroventricular injection of npy. |
1997-11-21 |
2023-08-12 |
rat |
| A O Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, S Whitebread, L Criscione, K G Hofbaue. Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides. Diabetes. vol 46. issue 11. 1997-11-21. PMID:9356028. |
analysis of the structure of feeding behavior revealed that prepro npy and y5 receptor antisense odns reduced food intake by inducing decreases in meal size and meal duration analogous to the orexigenic effects of npy that are mediated by increases in these parameters. |
1997-11-21 |
2023-08-12 |
rat |
| A O Schaffhauser, A Stricker-Krongrad, L Brunner, F Cumin, C Gerald, S Whitebread, L Criscione, K G Hofbaue. Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides. Diabetes. vol 46. issue 11. 1997-11-21. PMID:9356028. |
although changes in y5 receptor density could not be measured, the results with y5 antisense odns strongly suggest that this receptor subtype mediates the feeding response to exogenous and endogenous npy. |
1997-11-21 |
2023-08-12 |
rat |
| D Gayle, S E Ilyin, C R Plata-Salamá. Central nervous system IL-1 beta system and neuropeptide Y mRNAs during IL-1 beta-induced anorexia in rats. Brain research bulletin. vol 44. issue 3. 1997-11-06. PMID:9323447. |
interleukin-1 beta (il-1 beta) induces anorexia and neuropeptide y (npy) increases feeding by direct action in the central nervous system (cns). |
1997-11-06 |
2023-08-12 |
rat |
| A M Mistry, A G Swick, D R Romso. Leptin rapidly lowers food intake and elevates metabolic rates in lean and ob/ob mice. The Journal of nutrition. vol 127. issue 10. 1997-11-04. PMID:9311966. |
icv injection of 60 pmol leptin along with 230 pmol (2 microg) of neuropeptide y (npy) attenuated npy-induced feeding in ob/ob, but not in lean mice, suggesting an enhanced potential for crosstalk between the leptin and npy signaling systems in ob/ob mice lacking endogenous leptin. |
1997-11-04 |
2023-08-12 |
mouse |
| M Furuse, M Matsumoto, R Mori, K Sugahara, K Kano, S Hasegaw. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295227. |
the aim of the present study was to elucidate whether suppressed food intake by central injection of glp-1 would be modified by an appetite stimulant such as fasting and neuropeptide y (npy). |
1997-10-23 |
2023-08-12 |
chicken |
| M Furuse, M Matsumoto, R Mori, K Sugahara, K Kano, S Hasegaw. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295227. |
central administration of npy (2.5 microg/10 microl) greatly enhanced food intake, but co-injection of glp-1 (0.01, 0.02 or 0.03 microg/10 microl) decreased food intake in a dose-dependent fashion. |
1997-10-23 |
2023-08-12 |
chicken |
| M Furuse, M Matsumoto, R Mori, K Sugahara, K Kano, S Hasegaw. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295227. |
under glp-1 (0.03 microg/10 microl) treatment, whether npy modifies food intake of chicks in a dose-dependent manner was investigated by co-injection of graded levels of npy (0.4, 1.0 and 2.5 microg/10 microl). |
1997-10-23 |
2023-08-12 |
chicken |
| M Furuse, M Matsumoto, R Mori, K Sugahara, K Kano, S Hasegaw. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295227. |
glp-1 completely inhibited the effect of npy on food intake without a dose response. |
1997-10-23 |
2023-08-12 |
chicken |
| M Furuse, M Matsumoto, R Mori, K Sugahara, K Kano, S Hasegaw. Influence of fasting and neuropeptide Y on the suppressive food intake induced by intracerebroventricular injection of glucagon-like peptide-1 in the neonatal chick. Brain research. vol 764. issue 1-2. 1997-10-23. PMID:9295227. |
these results suggest that central glp-1 may interact with npy and may be the most potent inhibitor of food intake in the chicken. |
1997-10-23 |
2023-08-12 |
chicken |
| C Roche, P Boutin, C Dina, G Gyapay, A Basdevant, J Hager, B Guy-Grand, K Clément, P Frogue. Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity. Diabetologia. vol 40. issue 6. 1997-09-16. PMID:9222646. |
synthesis and release of neuropeptide y (npy) are both regulated by leptin binding to its hypothalamic receptor mediating some of the effects of leptin on food intake. |
1997-09-16 |
2023-08-12 |
human |
| C Roche, P Boutin, C Dina, G Gyapay, A Basdevant, J Hager, B Guy-Grand, K Clément, P Frogue. Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity. Diabetologia. vol 40. issue 6. 1997-09-16. PMID:9222646. |
moreover, npy administration is a powerful stimulant of feeding behaviour. |
1997-09-16 |
2023-08-12 |
human |
| A Shalev, S Vosmeer, U Kelle. Absence of short-term effects of glucagon-like peptide-1 and of hyperglycemia on plasma leptin levels in man. Metabolism: clinical and experimental. vol 46. issue 7. 1997-08-12. PMID:9225821. |
in rodents, leptin and the incretin glucagon-like peptide-1 (7-36) amide (glp-1) affect feeding at least in part via interaction with hypothalamic neuropeptide y (npy), suggesting that cross talk may exist between glp-1 and the ob gene product. |
1997-08-12 |
2023-08-12 |
human |
| A Sahu, C A Sninsky, S P Kalr. Evidence that hypothalamic neuropeptide Y gene expression and NPY levels in the paraventricular nucleus increase before the onset of hyperphagia in experimental diabetes. Brain research. vol 755. issue 2. 1997-08-07. PMID:9175903. |
several lines of evidence indicate that the site of npy action in transducing feeding signal may reside in the paraventricular nucleus (pvn) and neighboring sites in the hypothalamus. |
1997-08-07 |
2023-08-12 |
rat |