| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Morris, C F Tortelli, A Filippis, J Proiett. Reduced BAT function as a mechanism for obesity in the hypophagic, neuropeptide Y deficient monosodium glutamate-treated rat. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802441. |
we investigated the mechanism for the excess fat accumulation by studying the time course of changes in brain npy content, food intake, leptin levels and bat glut4 content after neonatal msg treatment. |
1999-01-19 |
2023-08-12 |
rat |
| M Shimada, N A Tritos, B B Lowell, J S Flier, E Maratos-Flie. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. vol 396. issue 6712. 1999-01-19. PMID:9872314. |
of these, neuropeptide y (npy) in the arcuate nucleus and melanin-concentrating hormone (mch) and orexins/hypocretins in the lateral hypothalamus have received attention because their expression is increased during fasting and because they promote feeding when administered centrally. |
1999-01-19 |
2023-08-12 |
mouse |
| M Shimada, N A Tritos, B B Lowell, J S Flier, E Maratos-Flie. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. vol 396. issue 6712. 1999-01-19. PMID:9872314. |
surprisingly, absence of the orexigenic neuropeptide npy fails to alter feeding or body weight in normal mice. |
1999-01-19 |
2023-08-12 |
mouse |
| C Broberger, J Johansen, C Johansson, M Schalling, T Hökfel. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proceedings of the National Academy of Sciences of the United States of America. vol 95. issue 25. 1999-01-14. PMID:9844012. |
our results show that arcuate npy neurons, identified by the presence of agrp, project more extensively in the brain than previously known and indicate that the feeding regulatory actions of npy may extend beyond the hypothalamus. |
1999-01-14 |
2023-08-12 |
mouse |
| M K Karvonen, U Pesonen, M Koulu, L Niskanen, M Laakso, A Rissanen, J M Dekker, L M Hart, R Valve, M I Uusitup. Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels. Nature medicine. vol 4. issue 12. 1998-12-23. PMID:9846584. |
neuropeptide y (npy), which is widely expressed in both the central and peripheral nervous systems, has an important role in the hypothalamic regulation of energy balance by stimulating food intake and favoring energy storage through increased lipoprotein lipase activity in white adipose tissue. |
1998-12-23 |
2023-08-12 |
human |
| M Yokosuka, B Xu, S Pu, P S Kalra, S P Kalr. Neural substrates for leptin and neuropeptide Y (NPY) interaction: hypothalamic sites associated with inhibition of NPY-induced food intake. Physiology & behavior. vol 64. issue 3. 1998-12-09. PMID:9748101. |
neural substrates for leptin and neuropeptide y (npy) interaction: hypothalamic sites associated with inhibition of npy-induced food intake. |
1998-12-09 |
2023-08-12 |
rat |
| M Yokosuka, B Xu, S Pu, P S Kalra, S P Kalr. Neural substrates for leptin and neuropeptide Y (NPY) interaction: hypothalamic sites associated with inhibition of NPY-induced food intake. Physiology & behavior. vol 64. issue 3. 1998-12-09. PMID:9748101. |
injection of leptin, the adipocyte hormone, inhibits neuropeptide y (npy)-induced feeding in the rat. |
1998-12-09 |
2023-08-12 |
rat |
| M Yokosuka, B Xu, S Pu, P S Kalra, S P Kalr. Neural substrates for leptin and neuropeptide Y (NPY) interaction: hypothalamic sites associated with inhibition of NPY-induced food intake. Physiology & behavior. vol 64. issue 3. 1998-12-09. PMID:9748101. |
because there is morphologic evidence of a link between magnocellular pvn and dorsomedial nucleus, these results suggest the functional involvement of leptin plus npy responsive elements in these sites in reduction of npy-induced feeding by leptin. |
1998-12-09 |
2023-08-12 |
rat |
| E M Kim, C C Welch, M K Grace, C J Billington, A S Levin. Effects of palatability-induced hyperphagia and food restriction on mRNA levels of neuropeptide-Y in the arcuate nucleus. Brain research. vol 806. issue 1. 1998-11-20. PMID:9739120. |
this study examined the effect of feeding either a bland cornstarch-based diet (bcd) or a highly palatable, high fat diet containing sucrose (hpd) on hypothalamic arcuate nucleus (arc) gene expression for neuropeptide-y (npy). |
1998-11-20 |
2023-08-12 |
human |
| E M Kim, C C Welch, M K Grace, C J Billington, A S Levin. Effects of palatability-induced hyperphagia and food restriction on mRNA levels of neuropeptide-Y in the arcuate nucleus. Brain research. vol 806. issue 1. 1998-11-20. PMID:9739120. |
however, feeding the hpd at 60% of ad libitum intake of the hpd, increased npy mrna levels in the arc relative to the other treatments (p<0.01). |
1998-11-20 |
2023-08-12 |
human |
| P Wyss, N Levens, A Stricker-Krongra. Stimulation of feeding in lean but not in obese Zucker rats by a selective neuropeptide Y Y5 receptor agonist. Neuroreport. vol 9. issue 11. 1998-11-18. PMID:9721954. |
we tested the effects of intracerebroventricular injections of human npy (hnpy) and [d-trp32]npy, a weak but selective npy y5 receptor agonist, on food intake in lean and obese zucker rats. |
1998-11-18 |
2023-08-12 |
human |
| P Wyss, N Levens, A Stricker-Krongra. Stimulation of feeding in lean but not in obese Zucker rats by a selective neuropeptide Y Y5 receptor agonist. Neuroreport. vol 9. issue 11. 1998-11-18. PMID:9721954. |
[d-trp32]npy (10 microg) stimulated feeding in lean but not in obese zucker rats. |
1998-11-18 |
2023-08-12 |
human |
| A Kask, L Rägo, J Harr. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. British journal of pharmacology. vol 124. issue 7. 1998-11-13. PMID:9723965. |
5 min before npy) at 30 min and 4 h, but not at 1 and 2 h. when animals were pretreated with diazepam (0.5 mg kg(-1), i.p., 20 min before npy), bibp3226 failed to suppress npy-induced feeding. |
1998-11-13 |
2023-08-12 |
human |
| A Kask, L Rägo, J Harr. Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. British journal of pharmacology. vol 124. issue 7. 1998-11-13. PMID:9723965. |
these results suggest that both the npy y1 and y5 receptors in the pvn are involved in the regulation of food intake. |
1998-11-13 |
2023-08-12 |
human |
| N A Tritos, D Vicent, J Gillette, D S Ludwig, E S Flier, E Maratos-Flie. Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus. Diabetes. vol 47. issue 11. 1998-11-10. PMID:9792536. |
administration of alpha-msh prevents only the orexigenic effect of mch, as we have previously shown, but does not prevent the effect of npy on food intake. |
1998-11-10 |
2023-08-12 |
rat |
| G A Bray, D A Yor. The MONA LISA hypothesis in the time of leptin. Recent progress in hormone research. vol 53. 1998-11-06. PMID:9769705. |
this syndrome is similar to the vmh syndrome and suggests that npy must be acting as an inhibitor of a feeding system. |
1998-11-06 |
2023-08-12 |
mouse |
| R D Palmiter, J C Erickson, G Hollopeter, S C Baraban, M W Schwart. Life without neuropeptide Y. Recent progress in hormone research. vol 53. 1998-11-06. PMID:9769708. |
npy-null mice display the normal voracious feeding response to injected npy. |
1998-11-06 |
2023-08-12 |
mouse |
| A Sah. Leptin decreases food intake induced by melanin-concentrating hormone (MCH), galanin (GAL) and neuropeptide Y (NPY) in the rat. Endocrinology. vol 139. issue 11. 1998-11-06. PMID:9794487. |
leptin decreases food intake induced by melanin-concentrating hormone (mch), galanin (gal) and neuropeptide y (npy) in the rat. |
1998-11-06 |
2023-08-12 |
rat |
| P A Rajakumar, J He, R A Simmons, S U Devaska. Effect of uteroplacental insufficiency upon brain neuropeptide Y and corticotropin-releasing factor gene expression and concentrations. Pediatric research. vol 44. issue 2. 1998-10-27. PMID:9702909. |
various hypothalamic functions such as feeding behavior, energy expenditure, body weight gain, level of anxiety, and sexual maturation are mediated by a balance between the concentrations of neuropeptide y (npy) and corticotropin-releasing factor (crf). |
1998-10-27 |
2023-08-12 |
Not clear |
| P A Rajakumar, J He, R A Simmons, S U Devaska. Effect of uteroplacental insufficiency upon brain neuropeptide Y and corticotropin-releasing factor gene expression and concentrations. Pediatric research. vol 44. issue 2. 1998-10-27. PMID:9702909. |
the iugr-associated pretranslational increase in npy and not crf peptide levels at d 21, may herald changes in feeding behavior during the postsuckling phase. |
1998-10-27 |
2023-08-12 |
Not clear |