| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D G Morgan, C J Small, S Abusnana, M Turton, I Gunn, M Heath, M Rossi, A P Goldstone, D O'Shea, K Meeran, M Ghatei, D M Smith, S Bloo. The NPY Y1 receptor antagonist BIBP 3226 blocks NPY induced feeding via a non-specific mechanism. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802432. |
animals previously injected with saline vehicle alone showed a normal npy feeding response. |
1999-01-19 |
2023-08-12 |
rat |
| D G Morgan, C J Small, S Abusnana, M Turton, I Gunn, M Heath, M Rossi, A P Goldstone, D O'Shea, K Meeran, M Ghatei, D M Smith, S Bloo. The NPY Y1 receptor antagonist BIBP 3226 blocks NPY induced feeding via a non-specific mechanism. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802432. |
this does not, however rule out a role for the y1 receptor in the control of food intake by npy. |
1999-01-19 |
2023-08-12 |
rat |
| G Hollopeter, J C Erickson, R J Seeley, D J Marsh, R D Palmite. Response of neuropeptide Y-deficient mice to feeding effectors. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802433. |
neuropeptide y (npy) is thought to be an important central regulator of feeding behavior and body weight. |
1999-01-19 |
2023-08-12 |
mouse |
| G Hollopeter, J C Erickson, R J Seeley, D J Marsh, R D Palmite. Response of neuropeptide Y-deficient mice to feeding effectors. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802433. |
however, mice lacking npy due to targeted genetic deletion do not display abnormalities in food intake or body weight with ad libitum access to food or in response to fasting. |
1999-01-19 |
2023-08-12 |
mouse |
| G Hollopeter, J C Erickson, R J Seeley, D J Marsh, R D Palmite. Response of neuropeptide Y-deficient mice to feeding effectors. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802433. |
the dose-dependent stimulation of food intake by central npy administration was unaltered in npy-/- mice. |
1999-01-19 |
2023-08-12 |
mouse |
| R Kozak, J G Mercer, A Burlet, K M Moar, C Burlet, B Bec. Hypothalamic neuropeptide Y content and mRNA expression in weanling rats subjected to dietary manipulations during fetal and neonatal life. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802435. |
hypothalamic neuropeptide y (npy) is present very early during the fetal life and is rapidly functional in the regulation of feeding behavior after birth. |
1999-01-19 |
2023-08-12 |
rat |
| S C Woods, D P Figlewicz, L Madden, D Porte, A J Sipols, R J Seele. NPY and food intake: discrepancies in the model. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802436. |
npy and food intake: discrepancies in the model. |
1999-01-19 |
2023-08-12 |
Not clear |
| S C Woods, D P Figlewicz, L Madden, D Porte, A J Sipols, R J Seele. NPY and food intake: discrepancies in the model. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802436. |
we discuss evidence suggesting that whereas npy activates feeding behavior by stimulating the complex sequence of behaviors beginning with the seeking and finding of food and ending with food ingestion, npy does not stimulate increased eating in the absence of the anticipatory preliminary behaviors. |
1999-01-19 |
2023-08-12 |
Not clear |
| A Kanatani, J Ito, A Ishihara, H Iwaasa, T Fukuroda, T Fukami, D J MacNeil, L H Van der Ploeg, M Ihar. NPY-induced feeding involves the action of a Y1-like receptor in rodents. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802437. |
these results indicate that the food intake evoked by npy might be mediated by the y1 receptor, rather than the y5 receptor. |
1999-01-19 |
2023-08-12 |
human |
| A O Schaffhauser, S Whitebread, R Haener, K G Hofbauer, A Stricker-Krongra. Neuropeptide Y Y1 receptor antisense oligodeoxynucleotides enhance food intake in energy-deprived rats. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802438. |
in the literature, conflicting data on the effect of npy y1 antisense oligodeoxynucleotides (odns) on food intake have been reported, describing either an increase or a decrease in feeding in antisense-treated animals. |
1999-01-19 |
2023-08-12 |
rat |
| A O Schaffhauser, S Whitebread, R Haener, K G Hofbauer, A Stricker-Krongra. Neuropeptide Y Y1 receptor antisense oligodeoxynucleotides enhance food intake in energy-deprived rats. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802438. |
these data suggest that the npy y1 receptor is not directly implicated in feeding in the rat when calorie intake is normal but might be specifically activated during energy deprivation. |
1999-01-19 |
2023-08-12 |
rat |
| J E McMinn, R J Seeley, C W Wilkinson, P J Havel, S C Woods, M W Schwart. NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802439. |
npy induced significant increases in food intake (75%), body weight (9%), plasma insulin (150%) and plasma leptin levels (300%) as compared to the i.c.v. |
1999-01-19 |
2023-08-12 |
human |
| J E McMinn, R J Seeley, C W Wilkinson, P J Havel, S C Woods, M W Schwart. NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802439. |
these findings indicate that npy-induced overfeeding suppresses arc npy mrna expression, and that this effect unlikely to be mediated by a direct action of npy, since it was abolished by limiting food intake in npy-treated animals to that observed in controls. |
1999-01-19 |
2023-08-12 |
human |
| F J Smith, L A Campfield, J A Moschera, P S Bailon, P Bur. Brain administration of OB protein (leptin) inhibits neuropeptide-Y-induced feeding in ob/ob mice. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802440. |
to test this hypothesis, the interaction of brain administration of exogenous ob protein and npy on the feeding behavior of ob/ob mice was examined. |
1999-01-19 |
2023-08-12 |
mouse |
| F J Smith, L A Campfield, J A Moschera, P S Bailon, P Bur. Brain administration of OB protein (leptin) inhibits neuropeptide-Y-induced feeding in ob/ob mice. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802440. |
human ob protein, in a dose-dependent manner, partially or completely blocked feeding induced by exogenous npy. |
1999-01-19 |
2023-08-12 |
mouse |
| F J Smith, L A Campfield, J A Moschera, P S Bailon, P Bur. Brain administration of OB protein (leptin) inhibits neuropeptide-Y-induced feeding in ob/ob mice. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802440. |
these results demonstrate that ob protein can functionally antagonize and dominate the actions of exogenous npy on feeding. |
1999-01-19 |
2023-08-12 |
mouse |
| M J Morris, C F Tortelli, A Filippis, J Proiett. Reduced BAT function as a mechanism for obesity in the hypophagic, neuropeptide Y deficient monosodium glutamate-treated rat. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802441. |
neuropeptide y (npy) exerts effects on food intake at the level of the paraventricular nucleus (pvn), which receives a dense projection from the arcuate nucleus. |
1999-01-19 |
2023-08-12 |
rat |
| M J Morris, C F Tortelli, A Filippis, J Proiett. Reduced BAT function as a mechanism for obesity in the hypophagic, neuropeptide Y deficient monosodium glutamate-treated rat. Regulatory peptides. vol 75-76. 1999-01-19. PMID:9802441. |
we investigated the mechanism for the excess fat accumulation by studying the time course of changes in brain npy content, food intake, leptin levels and bat glut4 content after neonatal msg treatment. |
1999-01-19 |
2023-08-12 |
rat |
| M Shimada, N A Tritos, B B Lowell, J S Flier, E Maratos-Flie. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. vol 396. issue 6712. 1999-01-19. PMID:9872314. |
of these, neuropeptide y (npy) in the arcuate nucleus and melanin-concentrating hormone (mch) and orexins/hypocretins in the lateral hypothalamus have received attention because their expression is increased during fasting and because they promote feeding when administered centrally. |
1999-01-19 |
2023-08-12 |
mouse |
| M Shimada, N A Tritos, B B Lowell, J S Flier, E Maratos-Flie. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature. vol 396. issue 6712. 1999-01-19. PMID:9872314. |
surprisingly, absence of the orexigenic neuropeptide npy fails to alter feeding or body weight in normal mice. |
1999-01-19 |
2023-08-12 |
mouse |