| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M C Flynn, C R Plata-Salamán, J M Ffrench-Mulle. Neuropeptide Y-related compounds and feeding. Physiology & behavior. vol 65. issue 4-5. 1999-05-17. PMID:10073499. |
npy, npy 3-36, and pp exhibited different potencies in enhancing 2-h food intake. |
1999-05-17 |
2023-08-12 |
Not clear |
| M C Flynn, C R Plata-Salamán, J M Ffrench-Mulle. Neuropeptide Y-related compounds and feeding. Physiology & behavior. vol 65. issue 4-5. 1999-05-17. PMID:10073499. |
the results support the notion that npy and its analogues induce a short-term feeding response by activating multiple receptor subtypes. |
1999-05-17 |
2023-08-12 |
Not clear |
| F Fukamauchi, O Aihara, M Kusakab. Reduced mRNA expression of neuropeptide Y in the limbic system of tenascin gene disrupted mouse brain. Neuropeptides. vol 32. issue 3. 1999-05-17. PMID:10189061. |
npy has been shown to affect emotion, circadian rhythm and food intake, and the present results suggest that the some behavioural abnormalities exhibited by tn-mutant mice may be in part due to the low level of expression of npy mrna in the limbic system. |
1999-05-17 |
2023-08-12 |
mouse |
| I A Zimanyi, Z Fathi, G S Poindexte. Central control of feeding behavior by neuropeptide Y. Current pharmaceutical design. vol 4. issue 4. 1999-05-10. PMID:10197048. |
there are many contradictory findings regarding which npy receptor mediates the effect of npy on food intake. |
1999-05-10 |
2023-08-12 |
human |
| I A Zimanyi, Z Fathi, G S Poindexte. Central control of feeding behavior by neuropeptide Y. Current pharmaceutical design. vol 4. issue 4. 1999-05-10. PMID:10197048. |
this article will review the effects of npy on the regulation of food intake and energy expenditure and will discuss the pharmacological and molecular evidence as to which npy receptor(s) mediate this effect. |
1999-05-10 |
2023-08-12 |
human |
| A Vezzani, G Sperk, W F Colmer. Neuropeptide Y: emerging evidence for a functional role in seizure modulation. Trends in neurosciences. vol 22. issue 1. 1999-05-04. PMID:10088996. |
in addition to its peripheral actions on cardiovascular regulation, much attention has, therefore, been devoted to the cns effects of npy because of its stimulatory properties on food intake, its role in anxiolysis and its putative involvement in memory retention. |
1999-05-04 |
2023-08-12 |
mouse |
| S P Kalra, M G Dube, S Pu, B Xu, T L Horvath, P S Kalr. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocrine reviews. vol 20. issue 1. 1999-04-22. PMID:10047974. |
2) similarly, anorexigenic signal-producing pathways (e.g., crh, glp-1, alpha msh, and cart) orchestrate neural events for dissipation of appetite and to terminate feeding, possibly by interrupting npy efflux and action at a postsynaptic level within the hypothalamus. |
1999-04-22 |
2023-08-12 |
rat |
| D G Baskin, J F Breininger, M W Schwart. Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. Diabetes. vol 48. issue 4. 1999-04-15. PMID:10102700. |
to test the hypothesis that the effects of food intake on arcuate nucleus npy activation are mediated by leptin, we performed simultaneous triple in situ hybridization colocalization studies to determine whether the subset of npy neurons that are activated by fasting preferentially expresses the long form of the leptin receptor (ob-rb). |
1999-04-15 |
2023-08-12 |
rat |
| D G Baskin, J F Breininger, M W Schwart. Leptin receptor mRNA identifies a subpopulation of neuropeptide Y neurons activated by fasting in rat hypothalamus. Diabetes. vol 48. issue 4. 1999-04-15. PMID:10102700. |
the results support the conclusion that the effect of food intake on npy neurons is mediated by the direct action of leptin via ob-rb receptors expressed by these npy cells. |
1999-04-15 |
2023-08-12 |
rat |
| A Plagemann, T Harder, A Rake, K Melchior, F Rittel, W Rohde, G Dörne. Hypothalamic insulin and neuropeptide Y in the offspring of gestational diabetic mother rats. Neuroreport. vol 9. issue 18. 1999-04-13. PMID:9926849. |
neuropeptide y (npy) is an important hypothalamic stimulator of food intake and body weight gain, and its levels are decreased by elevated insulin. |
1999-04-13 |
2023-08-12 |
rat |
| T Ida, K Nakahara, T Katayama, N Murakami, M Nakazat. Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats. Brain research. vol 821. issue 2. 1999-04-13. PMID:10064841. |
feeding behavior and food consumption increased dramatically within 10 min of injection of npy. |
1999-04-13 |
2023-08-12 |
rat |
| Y Yamamoto, Y Ueta, Y Date, M Nakazato, Y Hara, R Serino, M Nomura, I Shibuya, S Matsukura, H Yamashit. Down regulation of the prepro-orexin gene expression in genetically obese mice. Brain research. Molecular brain research. vol 65. issue 1. 1999-04-07. PMID:10036303. |
the gene expression of neuropeptide y (npy), a potent feeding stimulant, is known to be increased in ob/ob and db/db mice. |
1999-04-07 |
2023-08-12 |
mouse |
| K S Brown, R M Gentry, N E Rowlan. Central injection in rats of alpha-melanocyte-stimulating hormone analog: effects on food intake and brain Fos. Regulatory peptides. vol 78. issue 1-3. 1999-04-01. PMID:9879751. |
lcvt injection of ndp-msh greatly attenuated food intake stimulated in sated rats by acute cvt administration of neuropeptide y (npy). |
1999-04-01 |
2023-08-12 |
rat |
| K S Brown, R M Gentry, N E Rowlan. Central injection in rats of alpha-melanocyte-stimulating hormone analog: effects on food intake and brain Fos. Regulatory peptides. vol 78. issue 1-3. 1999-04-01. PMID:9879751. |
these and other data suggest that alpha-msh is an important endogenous regulator of food intake, possibly acting downstream of npy. |
1999-04-01 |
2023-08-12 |
rat |
| M G Dube, B Xu, P S Kalra, C A Sninsky, S P Kalr. Disruption in neuropeptide Y and leptin signaling in obese ventromedial hypothalamic-lesioned rats. Brain research. vol 816. issue 1. 1999-03-25. PMID:9878684. |
quite unexpectedly, npy concentrations in the hypothalamic paraventricular nucleus (pvn), a major site of npy release for stimulation of feeding, and in other sites, such as the dorsomedial nucleus, lateral hypothalamic area and median eminence-arcuate nucleus decreased, with the earliest diminution occurring on day 2 in the pvn only. |
1999-03-25 |
2023-08-12 |
rat |
| T M McShane, M E Wilson, P M Wis. Effects of lifelong moderate caloric restriction on levels of neuropeptide Y, proopiomelanocortin, and galanin mRNA. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 54. issue 1. 1999-03-23. PMID:10026650. |
we measured neuropeptide y (npy) and proopiomelanocortin (pomc) mrna in the arcuate nucleus (an), and galanin (gal) mrna in the an, paraventricular nucleus (pvn) and medial septum-diagonal band of broca in young, middle-aged and old female rats on a controlled feeding regimen. |
1999-03-23 |
2023-08-12 |
mouse |
| M I Uusitupa, M K Karvonen, U Pesonen, M Koul. Neuropeptide Y: a novel link between the neuroendocrine system and cholesterol metabolism. Annals of medicine. vol 30. issue 6. 1999-03-22. PMID:9920351. |
neuropeptide y (npy), which is widely expressed in both the central and peripheral nervous systems, is known to regulate food intake and energy balance but its role in cholesterol metabolism has remained almost untouched in former literature. |
1999-03-22 |
2023-08-12 |
human |
| S Dryden, L Pickavance, L Henderson, G William. Hyperphagia induced by hypoglycemia in rats is independent of leptin and hypothalamic neuropeptide Y (NPY). Peptides. vol 19. issue 9. 1999-03-15. PMID:9864062. |
leptin can inhibit feeding in hyperphagic hypoglycemic rats, and this may partly be attributable to its inhibition of the npy neurons. |
1999-03-15 |
2023-08-12 |
rat |
| C Cabot, M M Grasa, C Adán, J Pérez-Clausell, J Virgili, J Estruch, J A Fernández-Löpez, X Remesar, M Aleman. Oleoyl-estrone does not alter hypothalamic neuropeptide Y in Zucker lean and obese rats. Peptides. vol 19. issue 9. 1999-03-15. PMID:9864070. |
despite a negative energy balance and decreased food intake, there were practically no changes in npy with oe treatment. |
1999-03-15 |
2023-08-12 |
rat |
| C Cabot, M M Grasa, C Adán, J Pérez-Clausell, J Virgili, J Estruch, J A Fernández-Löpez, X Remesar, M Aleman. Oleoyl-estrone does not alter hypothalamic neuropeptide Y in Zucker lean and obese rats. Peptides. vol 19. issue 9. 1999-03-15. PMID:9864070. |
the results indicate that oleoyl-estrone does not act through npy in its control of either food intake or thermogenesis in lean and genetically obese rats. |
1999-03-15 |
2023-08-12 |
rat |