| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C D McMahon, D F Buxton, T H Elsasser, D R Gunter, L G Sanders, B P Steele, J L Sarti. Neuropeptide Y restores appetite and alters concentrations of GH after central administration to endotoxic sheep. The Journal of endocrinology. vol 161. issue 2. 1999-07-28. PMID:10320832. |
the objective of this study was to determine whether neuropeptide y (npy) and recombinant human interleukin-1 receptor antagonist (il-1ra) would: first, increase food intake; secondly, decrease concentrations of gh; thirdly, reduce ghrh-induced release of gh; and fourthly, reduce changes to concentrations of igf-i in plasma during experimental endotoxemia in sheep. |
1999-07-28 |
2023-08-12 |
human |
| K E Zakrzewska, A Sainsbury, I Cusin, J Rouru, B Jeanrenaud, F Rohner-Jeanrenau. Selective dependence of intracerebroventricular neuropeptide Y-elicited effects on central glucocorticoids. Endocrinology. vol 140. issue 7. 1999-07-15. PMID:10385413. |
infusion of npy and dexamethasone in adx rats increased food intake, body weight, plasma insulin, leptin, and triglyceride levels relative to vehicle-infused adx controls. |
1999-07-15 |
2023-08-12 |
rat |
| F Kokot, M Adamczak, A Wiecedil;cek, U Spiechowicz, J Mesjas. Plasma immunoreactive leptin and neuropeptide Y levels in kidney transplant patients. American journal of nephrology. vol 19. issue 1. 1999-07-08. PMID:10085446. |
leptin and neuropeptide y (npy) seem to play an important role in food intake and energy expenditure. |
1999-07-08 |
2023-08-12 |
Not clear |
| A Bischoff, M C Miche. Emerging functions for neuropeptide Y5 receptors. Trends in pharmacological sciences. vol 20. issue 3. 1999-07-08. PMID:10203865. |
the y5 subtype of neuropeptide y (npy) receptors has raised considerable interest as a mediator of npy-stimulated food intake, but with the advent of recent data, this hypothesis has come into question. |
1999-07-08 |
2023-08-12 |
Not clear |
| S Muroya, T Yada, S Shioda, M Takigaw. Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. Neuroscience letters. vol 264. issue 1-3. 1999-06-17. PMID:10320027. |
neuropeptide y (npy)-containing neurons in the hypothalamic arcuate nucleus (arc) have been implicated in the stimulation of feeding. |
1999-06-17 |
2023-08-12 |
rat |
| S Muroya, T Yada, S Shioda, M Takigaw. Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y. Neuroscience letters. vol 264. issue 1-3. 1999-06-17. PMID:10320027. |
the suggested role of these neurons is to transduce a reduction in the glucose concentration in the brain to the release of npy and, subsequently, stimulation of feeding. |
1999-06-17 |
2023-08-12 |
rat |
| C M Brown, P J Fletcher, D V Coscin. Neuropeptide Y-induced operant responding for sucrose is not mediated by dopamine. Peptides. vol 19. issue 10. 1999-06-15. PMID:9880070. |
neuropeptide y (npy) induces feeding in previously satiated animals after injection into the hypothalamus, especially the perifornical region (pfh). |
1999-06-15 |
2023-08-12 |
rat |
| B Murphy, C N Nunes, J J Ronan, C M Harper, M J Beall, M Hanaway, A M Fairhurst, L H Van der Ploeg, D E MacIntyre, T N Melli. Melanocortin mediated inhibition of feeding behavior in rats. Neuropeptides. vol 32. issue 6. 1999-06-07. PMID:9920446. |
the hypothesis that effects of melanocortins on feeding may be mediated via an npy related pathway was tested by co-injecting mtii and npy in a 2-h satiated food intake paradigm. |
1999-06-07 |
2023-08-12 |
mouse |
| B Murphy, C N Nunes, J J Ronan, C M Harper, M J Beall, M Hanaway, A M Fairhurst, L H Van der Ploeg, D E MacIntyre, T N Melli. Melanocortin mediated inhibition of feeding behavior in rats. Neuropeptides. vol 32. issue 6. 1999-06-07. PMID:9920446. |
mtii inhibited food intake induced by 5.0 microg hnpy in a dose dependent manner with the highest dose tested abolishing the npy feeding response. |
1999-06-07 |
2023-08-12 |
mouse |
| B Murphy, C N Nunes, J J Ronan, C M Harper, M J Beall, M Hanaway, A M Fairhurst, L H Van der Ploeg, D E MacIntyre, T N Melli. Melanocortin mediated inhibition of feeding behavior in rats. Neuropeptides. vol 32. issue 6. 1999-06-07. PMID:9920446. |
the studies suggest that melanocortins act via specific receptors to control food intake in rats, possibly via an npy related pathway. |
1999-06-07 |
2023-08-12 |
mouse |
| P Chen, C Li, C Haskell-Luevano, R D Cone, M S Smit. Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Endocrinology. vol 140. issue 6. 1999-06-03. PMID:10342854. |
during lactation, the levels of neuropeptide y (npy), which plays an important role in mediating food intake, are significantly elevated in a number of hypothalamic areas, including the arcuate nucleus (arh). |
1999-06-03 |
2023-08-12 |
Not clear |
| P Chen, C Li, C Haskell-Luevano, R D Cone, M S Smit. Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation. Endocrinology. vol 140. issue 6. 1999-06-03. PMID:10342854. |
the high degree of colocalization of agrp and npy, coupled with previous reports from our laboratory demonstrating increased npy expression in the arh in response to suckling, suggests that agrp and npy are coordinately regulated and may be involved in the increase in food intake during lactation. |
1999-06-03 |
2023-08-12 |
Not clear |
| B Xu, P S Kalra, W G Farmerie, S P Kalr. Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, proopiomelanocortin, and adipocyte leptin gene expression and secretion: effects of food restriction. Endocrinology. vol 140. issue 6. 1999-06-03. PMID:10342879. |
the participation of hypothalamic neuropeptide y (npy)-, galanin (gal)-, and opioid-producing neurons in the restraint on food intake exerted by adipocyte leptin has recently been recognized. |
1999-06-03 |
2023-08-12 |
rat |
| W T Chance, Z Tao, S Sheriff, A Balasubramania. WRYamide, a NPY-based tripeptide that antagonizes feeding in rats. Brain research. vol 803. issue 1-2. 1999-05-26. PMID:9729264. |
modifications of (d-trp32) neuropeptide y (npy) led to the development of potential peptide-based lower molecular weight (500-800 da) npy feeding antagonists. |
1999-05-26 |
2023-08-12 |
rat |
| P J Currie, D V Coscin. 5-Hydroxytryptaminergic receptor agonists: effects on neuropeptide Y potentiation of feeding and respiratory quotient. Brain research. vol 803. issue 1-2. 1999-05-26. PMID:9729393. |
in feeding tests conducted at the onset of the dark cycle, ru 24969, tfmpp and doi were administered 5 min prior to pvn injection of npy and food intake was measured 1 h postinjection. |
1999-05-26 |
2023-08-12 |
Not clear |
| S C Baraba. Neuropeptide Y and limbic seizures. Reviews in the neurosciences. vol 9. issue 2. 1999-05-21. PMID:9711903. |
because of the widespread distribution of npy, it has been implicated in the modulation of a variety of behaviors, including, but not limited to, circadian rhythms /1/, memory retention /33/, feeding /19,56/, sympathetic control of cardiovascular function /89/ and anxiety /42,43/. |
1999-05-21 |
2023-08-12 |
Not clear |
| S Iyengar, D L Li, R M Simmon. Characterization of neuropeptide Y-induced feeding in mice: do Y1-Y6 receptor subtypes mediate feeding? The Journal of pharmacology and experimental therapeutics. vol 289. issue 2. 1999-05-20. PMID:10215684. |
bibp3226, a nonpeptide y1 receptor antagonist, as well as its opposite enantiomer, bibp3435, which is inactive at y1 receptors, blocked feeding elicited by npy, [leu31pro34], or pyy at doses that did not cause overt behavioral dysfunction. |
1999-05-20 |
2023-08-12 |
mouse |
| S Iyengar, D L Li, R M Simmon. Characterization of neuropeptide Y-induced feeding in mice: do Y1-Y6 receptor subtypes mediate feeding? The Journal of pharmacology and experimental therapeutics. vol 289. issue 2. 1999-05-20. PMID:10215684. |
thus, by using currently available prototypic peptide npy receptor agonists for y1-y6 receptors and peptide and nonpeptide y1 receptor antagonists gr231118 and bibp3226, the mediation of npy-induced feeding cannot be unequivocally attributed to any one of the known npy receptors. |
1999-05-20 |
2023-08-12 |
mouse |
| S Iyengar, D L Li, R M Simmon. Characterization of neuropeptide Y-induced feeding in mice: do Y1-Y6 receptor subtypes mediate feeding? The Journal of pharmacology and experimental therapeutics. vol 289. issue 2. 1999-05-20. PMID:10215684. |
it is possible that npy-induced feeding is mediated either by a combination of more than one npy receptor subtype or by a unique npy receptor subtype. |
1999-05-20 |
2023-08-12 |
mouse |
| M C Flynn, C R Plata-Salamán, J M Ffrench-Mulle. Neuropeptide Y-related compounds and feeding. Physiology & behavior. vol 65. issue 4-5. 1999-05-17. PMID:10073499. |
neuropeptide y (npy) and related compounds increase short-term feeding. |
1999-05-17 |
2023-08-12 |
Not clear |