| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J Slawecki, M Betancourt, T Walpole, C L Ehler. Increases in sucrose consumption, but not ethanol consumption, following ICV NPY administration. Pharmacology, biochemistry, and behavior. vol 66. issue 3. 2000-10-05. PMID:10899375. |
npy's effects on feeding are primarily regulated through y5 receptors in hypothalamic sites, whereas npy-induced anxiolysis appears to be mediated by y1 receptors in the amygdala. |
2000-10-05 |
2023-08-12 |
rat |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
in the present study, third brain ventricle (intracerebroventricular) injection of goldfish npy (gnpy) caused a dose-dependent increase in food intake in goldfish, and intracerebroventricular administration of npy y1-receptor antagonist bibp-3226 decreased food intake; the actions of gnpy were blocked by simultaneous injection of bibp-3226. |
2000-10-05 |
2023-08-12 |
Not clear |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
goldfish maintained on a daily scheduled feeding regimen display an increase in npy mrna levels in the telencephalon-preoptic area and hypothalamus shortly before feeding; however, a decrease occured in optic tectum-thalamus. |
2000-10-05 |
2023-08-12 |
Not clear |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
in both fed and unfed fish, brain npy mrna levels decreased after scheduled feeding. |
2000-10-05 |
2023-08-12 |
Not clear |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
results from these studies demonstrate that npy is a physiological brain signal involved in feeding behavior in goldfish, mediating its effects, at least in part, through y1-like receptors in the brain. |
2000-10-05 |
2023-08-12 |
Not clear |
| M M Durkin, M W Walker, K E Smith, E L Gustafson, C Gerald, T A Branche. Expression of a novel neuropeptide Y receptor subtype involved in food intake: an in situ hybridization study of Y5 mRNA distribution in rat brain. Experimental neurology. vol 165. issue 1. 2000-10-04. PMID:10964488. |
our group has reported on the cloning of a novel rat neuropeptide y (npy) receptor involved in npy-induced food intake, the y5 receptor. |
2000-10-04 |
2023-08-12 |
rat |
| M M Durkin, M W Walker, K E Smith, E L Gustafson, C Gerald, T A Branche. Expression of a novel neuropeptide Y receptor subtype involved in food intake: an in situ hybridization study of Y5 mRNA distribution in rat brain. Experimental neurology. vol 165. issue 1. 2000-10-04. PMID:10964488. |
the distribution of this receptor mrna is consistent with a role for the y5 receptor in food intake and also suggests involvement in other processes mediated by npy. |
2000-10-04 |
2023-08-12 |
rat |
| B S Li, P R Kramer, W Zhao, W Ma, D A Stenger, L Zhan. Molecular cloning, expression, and characterization of rat homolog of human AP-2alpha that stimulates neuropeptide Y transcription activity in response to nerve growth factor. Molecular endocrinology (Baltimore, Md.). vol 14. issue 6. 2000-10-03. PMID:10847586. |
neuropeptide y (npy) plays an important role in the central regulation of neuronal activity, endocrine and sexual behavior, and food intake. |
2000-10-03 |
2023-08-12 |
mouse |
| S Pu, H Dhillon, L L Moldawer, P S Kalra, S P Kalr. Neuropeptide Y counteracts the anorectic and weight reducing effects of ciliary neurotropic factor. Journal of neuroendocrinology. vol 12. issue 9. 2000-10-02. PMID:10971807. |
infusion of cntf for 6-7 days on food intake and body weight as well as hypothalamic npy and orexin gene expression in male rats. |
2000-10-02 |
2023-08-12 |
rat |
| S Pu, H Dhillon, L L Moldawer, P S Kalra, S P Kalr. Neuropeptide Y counteracts the anorectic and weight reducing effects of ciliary neurotropic factor. Journal of neuroendocrinology. vol 12. issue 9. 2000-10-02. PMID:10971807. |
as expected, in fusion of npy alone (18 microg/day) augmented food intake (191.6% over the initial control, p < 0.05) and produced a 25.1% weight gain in conjunction with a 10-fold increase in serum leptin concentrations at the end of the 7-day period. |
2000-10-02 |
2023-08-12 |
rat |
| M E Bell, S Bhatnagar, S F Akana, S Choi, M F Dallma. Disruption of arcuate/paraventricular nucleus connections changes body energy balance and response to acute stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 17. 2000-09-28. PMID:10964976. |
food intake and body weight were correlated negatively to alphamsh, but not npy in pvn. |
2000-09-28 |
2023-08-12 |
rat |
| E M Parker, A Balasubramaniam, M Guzzi, D E Mullins, B G Salisbury, S Sheriff, M B Witten, J J Hw. [D-Trp(34)] neuropeptide Y is a potent and selective neuropeptide Y Y(5) receptor agonist with dramatic effects on food intake. Peptides. vol 21. issue 3. 2000-09-01. PMID:10793222. |
unlike the prototype selective npy y(5) receptor agonist [d-trp(32)]npy, [d-trp(34)]npy markedly increases food intake in rats, an effect that is blocked by the selective npy y(5) receptor antagonist cgp 71683a. |
2000-09-01 |
2023-08-12 |
rat |
| D J Goo. How tight are your genes? Transcriptional and posttranscriptional regulation of the leptin receptor, NPY, and POMC genes. Hormones and behavior. vol 37. issue 4. 2000-08-24. PMID:10860673. |
this article focuses on the regulation of the leptin receptor, npy, and pomc genes, and explores what is known about the regulation of these obesity genes in response to food intake or changes in body fat stores. |
2000-08-24 |
2023-08-12 |
human |
| L H Pheng, D Regol. Receptors for NPY in peripheral tissues bioassays. Life sciences. vol 67. issue 8. 2000-08-24. PMID:10946845. |
npy is the most abundant peptide in the brain and is involved in the regulation of food intake and of circadian rhythm. |
2000-08-24 |
2023-08-12 |
Not clear |
| A Kask, J Harr. Inhibition of amphetamine- and apomorphine-induced behavioural effects by neuropeptide Y Y(1) receptor antagonist BIBO 3304. Neuropharmacology. vol 39. issue 7. 2000-08-15. PMID:10760371. |
neuropeptide y (npy) has an important role in the regulation of stress responses and feeding behaviour. |
2000-08-15 |
2023-08-12 |
rat |
| J C Halford, J E Blundel. Separate systems for serotonin and leptin in appetite control. Annals of medicine. vol 32. issue 3. 2000-08-15. PMID:10821329. |
hypothalamic 5-ht receptor systems inhibit neuropeptide y (npy), a potent stimulator of hunger and food intake. |
2000-08-15 |
2023-08-12 |
Not clear |
| M D Li, J K Kane, S L Parker, K McAllen, S G Matta, B M Shar. Nicotine administration enhances NPY expression in the rat hypothalamus. Brain research. vol 867. issue 1-2. 2000-08-04. PMID:10837809. |
to determine whether the effects of nicotine on food intake and body weight were related to neuropeptide y (npy) expression, semi-quantitative reverse transcription-polymerase chain reaction (rt-pcr) and radioimmunoassay were utilized to measure npy mrna and peptide levels in various regions of the hypothalamus. |
2000-08-04 |
2023-08-12 |
human |
| M D Li, J K Kane, S L Parker, K McAllen, S G Matta, B M Shar. Nicotine administration enhances NPY expression in the rat hypothalamus. Brain research. vol 867. issue 1-2. 2000-08-04. PMID:10837809. |
in summary, our data suggest that the pharmacological effects of nicotine on food intake and body weight may be mediated by changes in hypothalamic npy levels, a neuropeptide that is pivotal to the hypothalamic regulation of food intake. |
2000-08-04 |
2023-08-12 |
human |
| A W Bannon, J Seda, M Carmouche, J M Francis, M H Norman, B Karbon, M L McCale. Behavioral characterization of neuropeptide Y knockout mice. Brain research. vol 868. issue 1. 2000-08-04. PMID:10841890. |
an extensive behavioral characterization was conducted with mice lacking the gene for neuropeptide y (npy) including response to 24 and 48 h fast and challenge with small molecule antagonists of npy receptors implicated in mediating the feeding effects of npy (i.e., y1 and y5). |
2000-08-04 |
2023-08-12 |
mouse |
| A W Bannon, J Seda, M Carmouche, J M Francis, M H Norman, B Karbon, M L McCale. Behavioral characterization of neuropeptide Y knockout mice. Brain research. vol 868. issue 1. 2000-08-04. PMID:10841890. |
one of the major findings was that the npy ko mice have a reduced food intake relative to wt controls in response to fasting. |
2000-08-04 |
2023-08-12 |
mouse |