| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Matsumoto, B T Marck, D A Gruenewald, T Wolden-Hanson, M A Naa. Aging and the neuroendocrine regulation of reproduction and body weight. Experimental gerontology. vol 35. issue 9-10. 2001-03-29. PMID:11113606. |
recently, we found that old male bn rats treated chronically with troglitazone, an insulin sensitizer, lowered high insulin and leptin levels, decreased body fat, and corrected the blunted food intake and body weight gain response to fasting without affecting basal arc npy gene expression. |
2001-03-29 |
2023-08-12 |
rat |
| A B Ballinger, G Williams, R Corder, T El-Haj, M J Farthin. Role of hypothalamic neuropeptide Y and orexigenic peptides in anorexia associated with experimental colitis in the rat. Clinical science (London, England : 1979). vol 100. issue 2. 2001-03-22. PMID:11171292. |
in vivo npy release and regional hypothalamic npy concentrations were measured in rats with trinitrobenzenesulphonic acid (tnbs)-induced colitis, healthy controls and animals pair-fed to match the food intake of the colitic group. |
2001-03-22 |
2023-08-12 |
rat |
| A B Ballinger, G Williams, R Corder, T El-Haj, M J Farthin. Role of hypothalamic neuropeptide Y and orexigenic peptides in anorexia associated with experimental colitis in the rat. Clinical science (London, England : 1979). vol 100. issue 2. 2001-03-22. PMID:11171292. |
food intake in the colitic group was assessed after administration of npy and two other potent orexigenic peptides: melanin-concentrating hormone (mch) and hypocretin (orexin-a). |
2001-03-22 |
2023-08-12 |
rat |
| A B Ballinger, G Williams, R Corder, T El-Haj, M J Farthin. Role of hypothalamic neuropeptide Y and orexigenic peptides in anorexia associated with experimental colitis in the rat. Clinical science (London, England : 1979). vol 100. issue 2. 2001-03-22. PMID:11171292. |
intraventricular or intrahypothalamic administration of npy, mch or hypocretin elicited a feeding response in healthy controls, but not in the colitic group. |
2001-03-22 |
2023-08-12 |
rat |
| A B Ballinger, G Williams, R Corder, T El-Haj, M J Farthin. Role of hypothalamic neuropeptide Y and orexigenic peptides in anorexia associated with experimental colitis in the rat. Clinical science (London, England : 1979). vol 100. issue 2. 2001-03-22. PMID:11171292. |
however, the failure of npy and other orexigenic peptides to increase feeding in the colitic group indicates suppression of feeding, either by inhibition of a common downstream hypothalamic neuronal pathway or by induction of one or more potent anorexigenic agents. |
2001-03-22 |
2023-08-12 |
rat |
| K P Rioux, T Le, M G Swai. Decreased orexigenic response to neuropeptide Y in rats with obstructive cholestasis. American journal of physiology. Gastrointestinal and liver physiology. vol 280. issue 3. 2001-03-22. PMID:11171627. |
neuropeptide y (npy) is a key factor in the neurochemical control of food intake, and obstructive cholestasis can be associated with disturbances in food intake. |
2001-03-22 |
2023-08-12 |
rat |
| K P Rioux, T Le, M G Swai. Decreased orexigenic response to neuropeptide Y in rats with obstructive cholestasis. American journal of physiology. Gastrointestinal and liver physiology. vol 280. issue 3. 2001-03-22. PMID:11171627. |
responsiveness to the orexigenic action of npy was tested by measuring food intake after intracerebroventricular injection of npy. |
2001-03-22 |
2023-08-12 |
rat |
| K P Rioux, T Le, M G Swai. Decreased orexigenic response to neuropeptide Y in rats with obstructive cholestasis. American journal of physiology. Gastrointestinal and liver physiology. vol 280. issue 3. 2001-03-22. PMID:11171627. |
in sham-resected rats, npy infusion strikingly increased food intake, whereas bile duct-resected (bdr) rats showed a consistent significantly impaired feeding response to npy at postlaparotomy days 2, 4, and 7. |
2001-03-22 |
2023-08-12 |
rat |
| A Kanatani, M Hata, S Mashiko, A Ishihara, O Okamoto, Y Haga, T Ohe, T Kanno, N Murai, Y Ishii, T Fukuroda, T Fukami, M Ihar. A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Molecular pharmacology. vol 59. issue 3. 2001-03-22. PMID:11179445. |
neuropeptide y (npy) is a potent feeding stimulant. |
2001-03-22 |
2023-08-12 |
mouse |
| A Kanatani, M Hata, S Mashiko, A Ishihara, O Okamoto, Y Haga, T Ohe, T Kanno, N Murai, Y Ishii, T Fukuroda, T Fukami, M Ihar. A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Molecular pharmacology. vol 59. issue 3. 2001-03-22. PMID:11179445. |
however, the existence of multiple npy receptors including a possible novel feeding receptor has made it difficult to determine the relative importance of the y1 receptor in feeding regulation. |
2001-03-22 |
2023-08-12 |
mouse |
| A Kanatani, M Hata, S Mashiko, A Ishihara, O Okamoto, Y Haga, T Ohe, T Kanno, N Murai, Y Ishii, T Fukuroda, T Fukami, M Ihar. A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Molecular pharmacology. vol 59. issue 3. 2001-03-22. PMID:11179445. |
herein we certified that the y1 receptor is a major feeding receptor of npy by using the potent and selective y1 antagonist (-)-2-[1-(3-chloro-5-isopropyloxycarbonylaminophenyl)ethylamino]-6-[2-(5-ethyl-4-methyl-1,3-thiazol-2-yl)ethyl]-4-morpholinopyridine (j-115814) and y1 receptor-deficient (y1-/-) mice. |
2001-03-22 |
2023-08-12 |
mouse |
| A Kanatani, M Hata, S Mashiko, A Ishihara, O Okamoto, Y Haga, T Ohe, T Kanno, N Murai, Y Ishii, T Fukuroda, T Fukami, M Ihar. A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Molecular pharmacology. vol 59. issue 3. 2001-03-22. PMID:11179445. |
intracerebroventricular (icv) (10-100 microg) and intravenous (iv) (0.3-30 mg/kg) administration of j-115814 significantly and dose-dependently suppressed feeding induced by icv npy (5 microg) in satiated sprague-dawley rats. |
2001-03-22 |
2023-08-12 |
mouse |
| A Kanatani, M Hata, S Mashiko, A Ishihara, O Okamoto, Y Haga, T Ohe, T Kanno, N Murai, Y Ishii, T Fukuroda, T Fukami, M Ihar. A typical Y1 receptor regulates feeding behaviors: effects of a potent and selective Y1 antagonist, J-115814. Molecular pharmacology. vol 59. issue 3. 2001-03-22. PMID:11179445. |
feeding induced by icv npy (5 microg) was unaffected by ip-injected j-115814 (30 mg/kg) in y1-/- mice and was suppressed in wild-type and y5-/- mice. |
2001-03-22 |
2023-08-12 |
mouse |
| K Ishizak. [Roles of neuropeptide Y in the expression of anticipatory corticosterone peak in rats under restricted daily feeding]. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 75. issue 6. 2001-03-15. PMID:11193932. |
these findings indicate that the npy neurons in the nst are specifically involved in the prefeeding corticosterone peak in the rats the under rf, while the npy neurons in the arc are involved in the feeding activity in general and stimulated by decreased food availability. |
2001-03-15 |
2023-08-12 |
rat |
| H Volkoff, R E Pete. Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain research. vol 887. issue 1. 2001-03-01. PMID:11134597. |
co-injection of cart peptide and neuropeptide y (npy) reduced the increase in feeding caused by injection of npy alone. |
2001-03-01 |
2023-08-12 |
Not clear |
| H Volkoff, R E Pete. Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain research. vol 887. issue 1. 2001-03-01. PMID:11134597. |
feeding behavior was stimulated relative to saline controls following injection of cart (62-76) alone and co-injection of npy and cart (62-76), but was not affected by treatment with cart (55-102) alone, npy and cart (55-102) or orexin a and cart (55-102). |
2001-03-01 |
2023-08-12 |
Not clear |
| J A Bonini, K A Jones, N Adham, C Forray, R Artymyshyn, M M Durkin, K E Smith, J A Tamm, L W Boteju, P P Lakhlani, R Raddatz, W J Yao, K L Ogozalek, N Boyle, E V Kouranova, Y Quan, P J Vaysse, J M Wetzel, T A Branchek, C Gerald, B Borowsk. Identification and characterization of two G protein-coupled receptors for neuropeptide FF. The Journal of biological chemistry. vol 275. issue 50. 2001-02-08. PMID:11024015. |
among the receptors with the highest amino acid sequence homology to npff1 and npff2 are members of the orexin, npy, and cholecystokinin families, which have been implicated in feeding. |
2001-02-08 |
2023-08-12 |
human |
| P S Kalra, S P Kalr. Use of antisense oligodeoxynucleotides to study the physiological functions of neuropeptide Y. Methods (San Diego, Calif.). vol 22. issue 3. 2001-02-02. PMID:11071820. |
microinjection directly into the arcuate nucleus attenuated npy-related feeding, however, to unequivocally block the effects of npy on feeding behavior, long-term inhibition of npy gene expression was required. |
2001-02-02 |
2023-08-12 |
human |
| P S Kalra, S P Kalr. Use of antisense oligodeoxynucleotides to study the physiological functions of neuropeptide Y. Methods (San Diego, Calif.). vol 22. issue 3. 2001-02-02. PMID:11071820. |
similar end-capped phosphorothioated odn sequences have been used to identify the npy receptor subtypes involved in stimulation of feeding. |
2001-02-02 |
2023-08-12 |
human |
| T Bungo, R Ando, S Kawakami, A Ohgushi, M Shimojo, Y Masuda, M Furus. Central bombesin inhibits food intake and the orexigenic effect of neuropeptide Y in the neonatal chick. Physiology & behavior. vol 70. issue 5. 2001-02-01. PMID:11111013. |
central administration of npy (2.5 microg) greatly enhanced food intake, but co-injection of bn (0.5 microg) suppressed food intake. |
2001-02-01 |
2023-08-12 |
chicken |