| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G Dube, T L Horvath, P S Kalra, S P Kalr. Evidence of NPY Y5 receptor involvement in food intake elicited by orexin A in sated rats. Peptides. vol 21. issue 10. 2000-12-18. PMID:11068104. |
evidence of npy y5 receptor involvement in food intake elicited by orexin a in sated rats. |
2000-12-18 |
2023-08-12 |
rat |
| M G Dube, T L Horvath, P S Kalra, S P Kalr. Evidence of NPY Y5 receptor involvement in food intake elicited by orexin A in sated rats. Peptides. vol 21. issue 10. 2000-12-18. PMID:11068104. |
since previous investigations demonstrated that an npy y1 receptor antagonist also inhibits feeding induced by orexin a, the current results further underscore the existence of a functional link between orexin and npy producing neurons as the orexin network appears to be capable of influencing npyergic signaling through y1 and y5 receptors to stimulate feeding. |
2000-12-18 |
2023-08-12 |
rat |
| J M Cerdá-Reverter, G Martínez-Rodríguez, I Anglade, O Kah, S Zanu. Peptide YY (PYY) and fish pancreatic peptide Y (PY) expression in the brain of the sea bass (Dicentrarchus labrax) as revealed by in situ hybridization. The Journal of comparative neurology. vol 426. issue 2. 2000-12-14. PMID:10982463. |
the receptor system of the npy family as well as gene expression within the main hypophysiotropic and feeding behavior areas suggest an involvement of both peptides in the control of food intake and pituitary secretion. |
2000-12-14 |
2023-08-12 |
Not clear |
| M Jang, A Mistry, A G Swick, D R Romso. Leptin rapidly inhibits hypothalamic neuropeptide Y secretion and stimulates corticotropin-releasing hormone secretion in adrenalectomized mice. The Journal of nutrition. vol 130. issue 11. 2000-12-08. PMID:11053526. |
leptin may rapidly inhibit food intake by altering the secretion of hypothalamic neuropeptides such as neuropeptide y (npy), a stimulator of food intake, and/or corticotropin-releasing hormone (crh), an inhibitor of food intake. |
2000-12-08 |
2023-08-12 |
mouse |
| M H Norman, N Chen, Z Chen, C Fotsch, C Hale, N Han, R Hurt, T Jenkins, J Kincaid, L Liu, Y Lu, O Moreno, V J Santora, J D Sonnenberg, W Karbo. Structure-activity relationships of a series of pyrrolo[3,2-d]pyrimidine derivatives and related compounds as neuropeptide Y5 receptor antagonists. Journal of medicinal chemistry. vol 43. issue 22. 2000-12-07. PMID:11063624. |
neuropeptide y (npy) has been shown to play an important role in the regulation of food intake and energy balance. |
2000-12-07 |
2023-08-12 |
human |
| G R Collier, J S McMillan, K Windmill, K Walder, J Tenne-Brown, A de Silva, J Trevaskis, S Jones, G J Morton, S Lee, G Augert, A Civitarese, P Z Zimme. Beacon: a novel gene involved in the regulation of energy balance. Diabetes. vol 49. issue 11. 2000-11-30. PMID:11078442. |
intracerebroventricular infusion of beacon resulted in a dose-dependent increase in food intake and body weight and an increase in hypothalamic expression of neuropeptide y (npy). |
2000-11-30 |
2023-08-12 |
Not clear |
| H Makimura, T M Mizuno, J Roberts, J Silverstein, J Beasley, C V Mobb. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes. vol 49. issue 11. 2000-11-30. PMID:11078460. |
in ob/ob mice, adrenalectomy reduced the levels of plasma glucose, serum insulin and corticosterone, and food intake toward or below wild-type levels, and it restored hypothalamic pomc and agrp mrna but not npy mrna to wild-type levels. |
2000-11-30 |
2023-08-12 |
mouse |
| P J Schwartz, S K Grote, K L Stephans, E M Adle. Zinc elevates neuropeptide Y levels in rat pheochromocytoma cells by a mechanism independent of L-channel mediated inhibition of release. Brain research. vol 877. issue 1. 2000-11-28. PMID:10980238. |
both zinc and neuropeptide y (npy) have been implicated as playing a role in seizures and feeding behavior. |
2000-11-28 |
2023-08-12 |
rat |
| J M Cerdá-Reverter, I Anglade, G Martínez-Rodríguez, D Mazurais, J A Muñoz-Cueto, M Carrillo, O Kah, S Zanu. Characterization of neuropeptide Y expression in the brain of a perciform fish, the sea bass (Dicentrarchus labrax). Journal of chemical neuroanatomy. vol 19. issue 4. 2000-11-28. PMID:11036237. |
in addition, npy gene was expressed within the primary visual, olfactory and gustatory circuits of teleost which, subsequently, project to hypothalamic feeding center in teleost fish. |
2000-11-28 |
2023-08-12 |
Not clear |
| C W Cheng, P Y Lin, M D Che. Zinc and nitric oxide synthase inhibitor L-NAME attenuate NPY-induced feeding in mice. Biological trace element research. vol 75. issue 1-3. 2000-11-16. PMID:11051593. |
the influences of zinc (zn) and the nitric oxide synthase (nos) inhibitor l-name on peripheral neuropeptide y (npy)-induced feeding in mice were investigated. |
2000-11-16 |
2023-08-12 |
mouse |
| T Ida, K Nakahara, T Kuroiwa, K Fukui, M Nakazato, T Murakami, N Murakam. Both corticotropin releasing factor and neuropeptide Y are involved in the effect of orexin (hypocretin) on the food intake in rats. Neuroscience letters. vol 293. issue 2. 2000-11-15. PMID:11027848. |
although the other appetite stimulating peptides; neuropeptide y (npy), agouti-related peptide (agrp) and one of the growth hormone releasing secretagogue (ghrp-6) stimulated dose-dependently the food intake during 2 h in the early light period, orexin did not increase significantly the food intake. |
2000-11-15 |
2023-08-12 |
rat |
| T Ida, K Nakahara, T Kuroiwa, K Fukui, M Nakazato, T Murakami, N Murakam. Both corticotropin releasing factor and neuropeptide Y are involved in the effect of orexin (hypocretin) on the food intake in rats. Neuroscience letters. vol 293. issue 2. 2000-11-15. PMID:11027848. |
orexin-stimulated feeding under these conditions was blocked by npy y1 receptor antagonist (1229u91). |
2000-11-15 |
2023-08-12 |
rat |
| X Wang, J R Day, Y Zhou, J L Beard, R Vasilatos-Younke. Evidence of a role for neuropeptide Y and monoamines in mediating the appetite-suppressive effect of GH. The Journal of endocrinology. vol 166. issue 3. 2000-10-18. PMID:10974656. |
neuropeptide y (npy) and monoamines play very important roles in the central regulation of feeding. |
2000-10-18 |
2023-08-12 |
Not clear |
| F Rohner-Jeanrenau. Hormonal regulation of energy partitioning. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 24 Suppl 2. 2000-10-10. PMID:10997599. |
to normal rats to mimic its central effects, leptin decreases npy levels, thus food intake and body weight. |
2000-10-10 |
2023-08-12 |
rat |
| G A Bra. Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 24 Suppl 2. 2000-10-10. PMID:10997600. |
chronic administration of neuropeptide y (npy) can produce chronically increased food intake and obesity. |
2000-10-10 |
2023-08-12 |
mouse |
| G A Bra. Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 24 Suppl 2. 2000-10-10. PMID:10997600. |
this syndrome is similar to the ventromedial hypothalamus (vmh) syndrome and suggests that npy must be acting as an inhibitory signal to stimulate a feeding system and inhibit sympathetic activity. |
2000-10-10 |
2023-08-12 |
mouse |
| A Milewicz, E Mikulski, B Bidzińsk. Plasma insulin, cholecystokinin, galanin, neuropeptide Y and leptin levels in obese women with and without type 2 diabetes mellitus. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 24 Suppl 2. 2000-10-10. PMID:10997641. |
experimental studies provided evidences that leptin, cholecystokinin (cck), galanin (gal), neuropeptide y (npy) and insulin are involved in feeding behaviour. |
2000-10-10 |
2023-08-12 |
human |
| C J Slawecki, M Betancourt, T Walpole, C L Ehler. Increases in sucrose consumption, but not ethanol consumption, following ICV NPY administration. Pharmacology, biochemistry, and behavior. vol 66. issue 3. 2000-10-05. PMID:10899375. |
npy's effects on feeding are primarily regulated through y5 receptors in hypothalamic sites, whereas npy-induced anxiolysis appears to be mediated by y1 receptors in the amygdala. |
2000-10-05 |
2023-08-12 |
rat |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
in the present study, third brain ventricle (intracerebroventricular) injection of goldfish npy (gnpy) caused a dose-dependent increase in food intake in goldfish, and intracerebroventricular administration of npy y1-receptor antagonist bibp-3226 decreased food intake; the actions of gnpy were blocked by simultaneous injection of bibp-3226. |
2000-10-05 |
2023-08-12 |
Not clear |
| Y K Narnaware, P P Peyon, X Lin, R E Pete. Regulation of food intake by neuropeptide Y in goldfish. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 3. 2000-10-05. PMID:10956262. |
goldfish maintained on a daily scheduled feeding regimen display an increase in npy mrna levels in the telencephalon-preoptic area and hypothalamus shortly before feeding; however, a decrease occured in optic tectum-thalamus. |
2000-10-05 |
2023-08-12 |
Not clear |