| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Neruja Loganathan, Emma K McIlwraith, Denise D Belsha. BPA Differentially Regulates NPY Expression in Hypothalamic Neurons Through a Mechanism Involving Oxidative Stress. Endocrinology. vol 161. issue 11. 2021-01-29. PMID:32960947. |
the neuropeptide y (npy) neurons of the hypothalamus control both food intake and reproduction and have emerged as potential targets of bpa. |
2021-01-29 |
2023-08-13 |
Not clear |
| Felicitas Lopez-Vicchi, Sharon R Ladyman, Ana Maria Ornstein, Papillon Gustafson, Penelope Knowles, Guillermina Maria Luque, David R Grattan, Damasia Becu-Villalobo. Chronic high prolactin levels impact on gene expression at discrete hypothalamic nuclei involved in food intake. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 3. 2021-01-25. PMID:31944423. |
furthermore, npy expression was increased in the dmn, probably contributing to increased food intake and decreased expression of uncoupling protein-1 in brown adipose tissue, both events favoring weight gain. |
2021-01-25 |
2023-08-13 |
mouse |
| Jérôme Roy, Laurence Larroquet, Anne Surget, Anthony Lanuque, Franck Sandres, Frederic Terrier, Geneviève Corraze, Jetty Chung-Yung Lee, Sandrine Skiba-Cass. Impact on cerebral function in rainbow trout fed with plant based omega-3 long chain polyunsaturated fatty acids enriched with DHA and EPA. Fish & shellfish immunology. vol 103. 2021-01-25. PMID:32473359. |
ω-3 lc-pufas enrichment decreased daily food intake and induced a simultaneous mrna expression increase in orexigenic transcript npy peptide and a decrease in anorexigen transcript pomca peptide in the hypothalamus. |
2021-01-25 |
2023-08-13 |
Not clear |
| Timothy Boswell, Ian C Dun. Regulation of Agouti-Related Protein and Pro-Opiomelanocortin Gene Expression in the Avian Arcuate Nucleus. Frontiers in endocrinology. vol 8. 2021-01-11. PMID:28450851. |
the proteins encoded by these genes exert comparable effects on food intake in birds after central administration to those seen in other vertebrates, with agrp and npy being orexigenic and cart and α-melanocyte-stimulating hormone anorexigenic. |
2021-01-11 |
2023-08-13 |
Not clear |
| Nicola J Lee, Yue Qi, Ronaldo F Enriquez, Chi Kin Ip, Herbert Herzo. Lack of NPY in neurotensin neurons leads to a lean phenotype. Neuropeptides. vol 80. 2020-12-10. PMID:31740068. |
neuropeptide y (npy) producing neurons in the arcuate nucleus (arc) of the hypothalamus are essential to the regulation of food intake and energy homeostasis. |
2020-12-10 |
2023-08-13 |
Not clear |
| Nicola J Lee, Yue Qi, Ronaldo F Enriquez, Chi Kin Ip, Herbert Herzo. Lack of NPY in neurotensin neurons leads to a lean phenotype. Neuropeptides. vol 80. 2020-12-10. PMID:31740068. |
the lack of npy in nts-positive neurons led to a marked reduction in fat mass and bodyweight as well as a significant reduction in food intake in male npy |
2020-12-10 |
2023-08-13 |
Not clear |
| Gabrielle C Winters, Gianluca Polese, Anna Di Cosmo, Leonid L Moro. Mapping of neuropeptide Y expression in Octopus brains. Journal of morphology. vol 281. issue 7. 2020-12-10. PMID:32384206. |
neuropeptide y (npy) is an evolutionarily conserved neurosecretory molecule implicated in a diverse complement of functions across taxa and in regulating feeding behavior and reproductive maturation in octopus. |
2020-12-10 |
2023-08-13 |
Not clear |
| Ayelén Melisa Blanco, Juan Ignacio Bertucci, Azadeh Hatef, Suraj Unniappa. Feeding and food availability modulate brain-derived neurotrophic factor, an orexigen with metabolic roles in zebrafish. Scientific reports. vol 10. issue 1. 2020-12-04. PMID:32612127. |
intraperitoneal injection of bdnf increased food intake at 1, 2 and 6 h post-administration, and caused an upregulation of brain npy, agrp and orexin, foregut ghrelin, and hepatic leptin mrnas, and a reduction in brain nucb2. |
2020-12-04 |
2023-08-13 |
zebrafish |
| Yoko Urata, Reza Salehi, Patricia D A Lima, Yutaka Osuga, Benjamin K Tsan. Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner. Journal of ovarian research. vol 13. issue 1. 2020-10-19. PMID:31915051. |
neuronal neuropeptide y (npy) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its function in ovarian follicular development is not clear. |
2020-10-19 |
2023-08-13 |
Not clear |
| Kouhei Matsuda, Kairi Matsumura, Syun-Suke Shimizu, Tomoya Nakamachi, Norifumi Konn. Neuropeptide Y-Induced Orexigenic Action Is Attenuated by the Orexin Receptor Antagonist in Bullfrog Larvae. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28420957. |
in fact, food intake is enhanced by intracerebroventricular (icv) administration of neuropeptide y (npy) and orexin a. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kouhei Matsuda, Kairi Matsumura, Syun-Suke Shimizu, Tomoya Nakamachi, Norifumi Konn. Neuropeptide Y-Induced Orexigenic Action Is Attenuated by the Orexin Receptor Antagonist in Bullfrog Larvae. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28420957. |
the stimulatory effect of icv injection of npy at 10 pmol/g body weight (bw) on food intake was abolished by treatment with sb334867 at 60 pmol/g bw. |
2020-10-01 |
2023-08-13 |
Not clear |
| María J Delgado, José M Cerdá-Reverter, José L Soenga. Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28694769. |
as in mammals, a complex hypothalamic circuit including two populations of neurons: one co-expressing neuropeptide y (npy) and agouti-related peptide (agrp) and the second one population co-expressing pro-opiomelanocortin (pomc) and cocaine- and amphetamine-regulated transcript (cart) is involved in the integration of information relating to food intake control. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yiru Huang, Zhenyan He, Yong Gao, Linh Lieu, Ting Yao, Jia Sun, Tiemin Liu, Chris Javadi, Maria Box, Sadia Afrin, Hongbo Guo, Kevin W William. Phosphoinositide 3-Kinase Is Integral for the Acute Activity of Leptin and Insulin in Male Arcuate NPY/AgRP Neurons. Journal of the Endocrine Society. vol 2. issue 6. 2020-10-01. PMID:29850651. |
neuropeptide y (npy)/agouti-related protein (agrp) neurons in the arcuate nucleus of the hypothalamus are part of a neuroendocrine feedback loop that regulates feeding behavior and glucose homeostasis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shu-Chen Chu, Pei-Ni Chen, Ching-Han Yu, Yih-Shou Hsieh, Dong-Yih Ku. Role of hypoxia-inducible factor-1α in regulating oxidative stress and hypothalamic neuropeptides-mediated appetite control. Brain research. vol 1721. 2020-10-01. PMID:31295466. |
results revealed that feeding behavior and npy decreased, whereas hif-1α/dna binding activity and sod, pomc, pi3k, and nf-κb expression levels increased in amph-treated rats. |
2020-10-01 |
2023-08-13 |
rat |
| Kazunori Kawamura, Wakana Mori, Masayuki Fujinaga, Tomoteru Yamasaki, Yiding Zhang, Hidekatsu Wakizaka, Akiko Hatori, Lin Xie, Katsushi Kumata, Takayuki Ohkubo, Yusuke Kurihara, Masanao Ogawa, Nobuki Nengaki, Ming-Rong Zhan. Radiosynthesis and in vivo evaluation of EJNMMI radiopharmacy and chemistry. vol 4. issue 1. 2020-09-28. PMID:31659508. |
radiosynthesis and in vivo evaluation of neuropeptide y (npy) has been implicated in a wide variety of physiological processes, including feeding, learning, memory, emotion, cardiovascular homeostasis, hormone secretion, and circadian rhythms. |
2020-09-28 |
2023-08-13 |
Not clear |
| Shoichi Fujita, Kazuhisa Honda, Mika Yamaguchi, Satoshi Fukuzo, Takaoki Saneyasu, Hiroshi Kamisoyam. Role of Insulin-like Growth Factor-1 in the Central Regulation of Feeding Behavior in Chicks. The journal of poultry science. vol 56. issue 4. 2020-09-28. PMID:32055224. |
neuropeptide y (npy, a hypothalamic orexigenic neuropeptide), agouti-related protein (agrp, a hypothalamic orexigenic neuropeptide), and proopiomelanocortin (pomc, the precursor of hypothalamic anorexigenic neuropeptides) play important roles in the regulation of food intake in both mammals and chickens. |
2020-09-28 |
2023-08-13 |
Not clear |
| Wiebe Venema, Ilenia Severi, Jessica Perugini, Eleonora Di Mercurio, Marco Mainardi, Margherita Maffei, Saverio Cinti, Antonio Giordan. Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32528252. |
to gain further insights into the mechanism(s) underlying its satiety effect, we: (i) evaluated the cntf-dependent activation of the janus kinase 2 (jak2) and signal transducer and activator of transcription 3 (stat3) pathway in mouse models where neuropeptide y (npy) and pro-opiomelanocortin (pomc) neurons can be identified by green fluorescent protein (gfp); and (ii) assessed whether cntf promotes leptin signaling in hypothalamic feeding centers. |
2020-09-28 |
2023-08-13 |
mouse |
| Wiebe Venema, Ilenia Severi, Jessica Perugini, Eleonora Di Mercurio, Marco Mainardi, Margherita Maffei, Saverio Cinti, Antonio Giordan. Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32528252. |
collectively, these data suggest that exogenously administered cntf reduces food intake by exerting a leptin-like action on distinctive npy arc neurons and by promoting leptin signaling in hypothalamic feeding centers. |
2020-09-28 |
2023-08-13 |
mouse |
| Myrtille C R Gumbs, Anna H Vuuregge, Leslie Eggels, Unga A Unmehopa, Khalid Lamuadni, Joram D Mul, Susanne E la Fleu. Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats. The Journal of comparative neurology. vol 527. issue 16. 2020-09-18. PMID:30950054. |
the hypothalamic neuropeptide y (npy) circuitry is a key regulator of feeding behavior. |
2020-09-18 |
2023-08-13 |
rat |
| Myrtille C R Gumbs, Anna H Vuuregge, Leslie Eggels, Unga A Unmehopa, Khalid Lamuadni, Joram D Mul, Susanne E la Fleu. Afferent neuropeptide Y projections to the ventral tegmental area in normal-weight male Wistar rats. The Journal of comparative neurology. vol 527. issue 16. 2020-09-18. PMID:30950054. |
npy also acts in the mesolimbic dopaminergic circuitry, where it can increase motivational aspects of feeding behavior through effects on dopamine output in the nucleus accumbens (nac) and on neurotransmission in the ventral tegmental area (vta). |
2020-09-18 |
2023-08-13 |
rat |